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See detailContinuous stroke volume estimation from aortic pressure using zero dimensional cardiovascular model: proof of concept study from porcine experiments.
Kamoi, Shun; Pretty, Christopher; Docherty, Paul et al

in PloS one (2014), 9(7), 102476

INTRODUCTION: Accurate, continuous, left ventricular stroke volume (SV) measurements can convey large amounts of information about patient hemodynamic status and response to therapy. However, direct ... [more ▼]

INTRODUCTION: Accurate, continuous, left ventricular stroke volume (SV) measurements can convey large amounts of information about patient hemodynamic status and response to therapy. However, direct measurements are highly invasive in clinical practice, and current procedures for estimating SV require specialized devices and significant approximation. METHOD: This study investigates the accuracy of a three element Windkessel model combined with an aortic pressure waveform to estimate SV. Aortic pressure is separated into two components capturing; 1) resistance and compliance, 2) characteristic impedance. This separation provides model-element relationships enabling SV to be estimated while requiring only one of the three element values to be known or estimated. Beat-to-beat SV estimation was performed using population-representative optimal values for each model element. This method was validated using measured SV data from porcine experiments (N = 3 female Pietrain pigs, 29-37 kg) in which both ventricular volume and aortic pressure waveforms were measured simultaneously. RESULTS: The median difference between measured SV from left ventricle (LV) output and estimated SV was 0.6 ml with a 90% range (5th-95th percentile) -12.4 ml-14.3 ml. During periods when changes in SV were induced, cross correlations in between estimated and measured SV were above R = 0.65 for all cases. CONCLUSION: The method presented demonstrates that the magnitude and trends of SV can be accurately estimated from pressure waveforms alone, without the need for identification of complex physiological metrics where strength of correlations may vary significantly from patient to patient. [less ▲]

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See detailContinuous subcutaneous insulin infusion with short-acting insulin analogues or human regular insulin: efficacy, safety, quality of life, and cost-effectiveness.
Radermecker, Régis ULg; Scheen, André ULg

in Diabetes/Metabolism Research & Reviews (2004), 20(3), 178-88

Portable insulin infusion devices are effective and safe insulin delivery systems for managing diabetes mellitus, especially type 1 diabetes. Rapidly absorbed insulin analogues, such as insulin lispro or ... [more ▼]

Portable insulin infusion devices are effective and safe insulin delivery systems for managing diabetes mellitus, especially type 1 diabetes. Rapidly absorbed insulin analogues, such as insulin lispro or insulin aspart, may offer an advantage over regular human insulin for insulin pumps. Several open-label randomised crossover trials demonstrated that continuous subcutaneous insulin infusion (CSII) with insulin lispro provided a better control of postprandial hyperglycaemia and a slightly but significantly lower glycated haemoglobin level, with lower daily insulin requirement and similar or even less hypoglycaemic episodes. A CSII study comparing insulin lispro and insulin aspart demonstrated similar results with the two analogues, and better results than those with regular insulin. Because these analogues have a quicker onset and a shorter duration of action than regular insulin, one might expect an earlier and greater metabolic deterioration in case of CSII interruption, but a more rapid correction of metabolic abnormalities after insulin boluses when reactivating the pump. These expectations were confirmed in randomised protocols comparing the metabolic changes occurring during and after CSII interruption of various durations when the pump infused either insulin lispro or regular insulin. The extra cost resulting from the use of CSII and insulin analogues in diabetes management should be compensated for by better metabolic control and quality of life. In conclusion, CSII delivering fast-acting insulin analogues may be considered as one of the best methods to replace insulin in a physiological manner by mimicking meal and basal insulin requirements, without higher risk of hypoglycaemia or ketoacidosis in well-educated diabetic patients. [less ▲]

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See detailContinuous Surface-point Distributions for 3D Object Pose Estimation and Recognition
Detry, Renaud ULg; Piater, Justus ULg

in Asian Conference on Computer Vision (2010)

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See detailContinuous synthesis of porous carbon xerogel beads.
Eskenazi, David ULg; Kreit, Patrick ULg; Compère, Philippe ULg et al

in Proceedings of the International Carbon Conference 2012 (2012, June 17)

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See detailContinuous-flow production of alkyl nitrites
Monbaliu, Jean-Christophe ULg; Jorda, Jeremy; Chevalier, Bérengère et al

in Chimica Oggi = Chemistry Today (2011), 29

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See detailContinuous-state reinforcement learning with fuzzy approximation
Busoniu, Lucian; Ernst, Damien ULg; De Schutter, Bart et al

in Tuyls, K.; Nowé, A.; Guessoum, Z. (Eds.) et al Adaptive Agents and Multi-Agent Systems III, Adaptation and Multi-Agent Learning (2008)

Reinforcement learning (RL) is a widely used learning paradigm for adaptive agents. There exist several convergent and consistent RL algorithms which have been intensively studied. In their original form ... [more ▼]

Reinforcement learning (RL) is a widely used learning paradigm for adaptive agents. There exist several convergent and consistent RL algorithms which have been intensively studied. In their original form, these algorithms require that the environment states and agent actions take values in a relatively small discrete set. Fuzzy representations for approximate, model-free RL have been proposed in the literature for the more difficult case where the state-action space is continuous. In this work, we propose a fuzzy approximation architecture similar to those previously used for Q-learning, but we combine it with the model-based Q-value iteration algorithm. We prove that the resulting algorithm converges. We also give a modified, asynchronous variant of the algorithm that converges at least as fast as the original version. An illustrative simulation example is provided. [less ▲]

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See detailContinuous-state reinforcement learning with fuzzy approximation
Busoniu, Lucian; Ernst, Damien ULg; Babuska, Robert et al

in Proceedings of the 7th European Symposium on Adaptive Learning Agents and Multi-Agent Systems (ALAMAS-07) (2007)

Reinforcement learning (RL) is a widely used learning paradigm for adaptive agents. Well-understood RL algorithms with good convergence and consistency properties exist. In their original form, these ... [more ▼]

Reinforcement learning (RL) is a widely used learning paradigm for adaptive agents. Well-understood RL algorithms with good convergence and consistency properties exist. In their original form, these algorithms require that the environment states and agent actions take values in a relatively small discrete set. Fuzzy representations for approximate, model-free RL have been proposed in the literature for the more difficult case where the state-action space is continuous. In this work, we propose a fuzzy approximation structure similar to those previously used for Q-learning, but we combine it with the model-based Q-value iteration algorithm. We show that the resulting algorithm converges. We also give a modif ed, serial variant of the algorithm that converges at least as fast as the original version. An illustrative simulation example is provided. [less ▲]

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See detailContinuous-time susbspace flows related to the symmetric eigenvalue problem
Absil, Pierre-Antoine; Sepulchre, Rodolphe ULg; Mahony, Robert

in Pacific Journal of Optimization (2008), 4(2), 179--194

The classes of continuous-time flows on Rn×p that induce the same flow on the set of p-dimensional subspaces of Rn are described. The power flow is briefly reviewed in this framework, and a subspace ... [more ▼]

The classes of continuous-time flows on Rn×p that induce the same flow on the set of p-dimensional subspaces of Rn are described. The power flow is briefly reviewed in this framework, and a subspace generalization of the Rayleigh quotient flow [Linear Algebra Appl. 368C, 2003, pp. 343–357] is proposed and analyzed. This new flow displays a property akin to deflation in finite time. [less ▲]

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See detailA Continuum Damage Mechanics based bone remodelling model in a finite strain framework
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg

in ECCM 2010, 4th European Conference on Computational Mechanics (2010)

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See detailA Continuum Damage Mechanics Model for the Analysis of the Crashworthiness of Composite Structures: A work in progress
Chiu, Louis N S; Falzon, Brian G; Boman, Romain ULg

in Proceedings of the 15th Australian Aeronautical Conference (2013, February)

The crashworthiness capability of an aircraft structure is dependent on its ability to attenuate crash loading via the controlled deformation of energy absorbing devices. An energy-based constitutive ... [more ▼]

The crashworthiness capability of an aircraft structure is dependent on its ability to attenuate crash loading via the controlled deformation of energy absorbing devices. An energy-based constitutive relation was employed to model the behaviour of carbon fibre reinforced epoxy resin composite material under crush loading. Each of the damage modes in the fibre and matrix was treated separately with its own damage initiation and progression relationships as well as a damage parameter that tracks damage progression. Each damage parameter dictates the reduction in stiffness in the respective principal loading directions. This model was implemented for a 3D solid brick element in contrast to shell-based formulations currently available. Crushing composite structures were modelled and the results validated against experimental data. The force-displacement response / specific energy absorption and the failure modes obtained from the simulation show that the underlying physics of the crushing have been captured by the proposed model but that further work is required for reliable quantitative correlation. [less ▲]

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See detailA continuum damage model for alveolar bone remodeling
Mengoni, Marlène ULg; Ponthot, Jean-Philippe ULg

in Fourth International Conference on Advance COmputational Methods in ENgineering - ACOMEN 2008 (2008, May)

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See detailThe continuum of cytokine involvement in the physiology of reproduction
Geenen, Vincent ULg; Hazee, Marie-Thérèse ULg; Goxe, Béatrice et al

in GENESIS (1995), 14

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See detailThe continuum of cytokine involvement in the reproductive process
Geenen, Vincent ULg

Conference (1995, September)

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See detailThe Continuum of Grief: From Scandinavian Mythology to Zen Buddhism: JanetFrame’s Intertextual Strategies in Snowman, Snowman
Gabrielle, Cindy ULg

in Sino-USEnglish Teaching (2012), 9(10), 1627-1636

In the wake of Richards Benton’s “Keats and Zen” (published in Philosophy East and West (1966)), this paper sets out to examine Janet Frame’s appropriation of Buddhist philosophy in Snowman, Snowman (1962 ... [more ▼]

In the wake of Richards Benton’s “Keats and Zen” (published in Philosophy East and West (1966)), this paper sets out to examine Janet Frame’s appropriation of Buddhist philosophy in Snowman, Snowman (1962). The novella’s allusions to a Buddhist-like epistemology, together with its subtle references to Scandinavian myths, however, have so far remained uncovered and are therefore best approached in the light of what has been called “the suppressed intertextuality in post-colonial writing”. The author’s intention in this paper is twofold: On the one hand, the author will suggest that post-colonial writers do not necessarily write against the Western canon and that maintaining the contrary amounts to vindicating the centrality of imperial texts in the contemporary literary scene—an endeavour which is hardly post-colonial. On the other hand, the author will go some way towards shifting eastward the core of Frame’s ontology by suggesting that her poetics is anchored not only in Western thinking, but also, perhaps more importantly so, in Eastern philosophy. The author’s primary impulse, however, in examining the interplay between canonical and peripheral intertextualities, is to illuminate in fundamental fashion the haunting beauty of the writer’s universe and the lyricism of Snowman, Snowman. [less ▲]

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See detailContinuum-level modelling of cellular adhesion and matrix production in aggregates.
Geris, Liesbet ULg; Ashbourn, Joanna M A; Clarke, Tim

in Computer Methods in Biomechanics & Biomedical Engineering (2011), 14(5), 403-10

Key regulators in tissue-engineering processes such as cell culture and cellular organisation are the cell-cell and cell-matrix interactions. As mathematical models are increasingly applied to investigate ... [more ▼]

Key regulators in tissue-engineering processes such as cell culture and cellular organisation are the cell-cell and cell-matrix interactions. As mathematical models are increasingly applied to investigate biological phenomena in the biomedical field, it is important, for some applications, that these models incorporate an adequate description of cell adhesion. This study describes the development of a continuum model that represents a cell-in-gel culture system used in bone-tissue engineering, namely that of a cell aggregate embedded in a hydrogel. Cell adhesion is modelled through the use of non-local (integral) terms in the partial differential equations. The simulation results demonstrate that the effects of cell-cell and cell-matrix adhesion are particularly important for the survival and growth of the cell population and the production of extracellular matrix by the cells, concurring with experimental observations in the literature. [less ▲]

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See detailLes contours de l'entreprise sociale
Marée, Michel ULg; Mertens de Wilmars, Sybille ULg

in Mertens de Wilmars, Sybille (Ed.) La gestion des entreprises sociales (2010)

Ce chapitre décrit d'abord successivement les éléments fondateurs du concept d'entreprise sociale, en précisant en quoi ce type d'entreprise constitue un "choix d'entreprendre" différent. Il passe ensuite ... [more ▼]

Ce chapitre décrit d'abord successivement les éléments fondateurs du concept d'entreprise sociale, en précisant en quoi ce type d'entreprise constitue un "choix d'entreprendre" différent. Il passe ensuite en revue les formes juridiques choisies par les entreprises sociales et donne un aperçu statistique de leur poids dans l'économie belge. Il présente également les grandes finalités qu'elles poursuivent et le modèle d'entreprise qu'elles mettent en oeuvre. Enfin, il énonce les questions de gestion que pose a priori ce modèle d'entreprise. [less ▲]

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See detailContours de la nouvelle mesure générale anti-abus
Bourgeois, Marc ULg

Report (2011)

Detailed reference viewed: 29 (7 ULg)