Design of perfluorinated macroligands for the implementation of atom transfer radical polymerization in supercritical carbon dioxideGrignard, Bruno ![]() Doctoral thesis (2007) Detailed reference viewed: 74 (49 ULg) The design of performance monitoring systems in healthcare organizations : a stakeholder perspective; Van Caillie, Didier ![]() in European Journal of Public Health (n.d.) Monitoring the hospital’s performance is evolving over time in search of more efficiency by integrating additional levels of care, reducing costs and keeping stuff up-to-date. To fulfill these three ... [more ▼] Monitoring the hospital’s performance is evolving over time in search of more efficiency by integrating additional levels of care, reducing costs and keeping stuff up-to-date. To fulfill these three potentially divergent aspects and to monitor performance, healthcare administrators are using dissimilar management control tools. To explain why, we suggest to go beyond traditional contingent factors to assess the role of the different stakeholders (governments, patients, authorities, personnel and administrators) that are at the heart of any healthcare organization. So, the main interest of our empirical study is to appraise how healthcare managers can foster strategic “alignment” in chaotic environments. To investigate this subject, we rely first on seminal studies to appraise the role of the main healthcare players and their influence on some organizational attributes (essentially size, lifecycle, structure, climate and technology in use). We then consider the managerial awareness and the perception of a suitable management control system (MCS) to promote a strategy-focused organization. Our methodology is based on a qualitative approach of twenty-two case studies, lead in two heterogeneous environments (Belgium and Lebanon). This method allows to illustrate, for each healthcare player, its positioning within the healthcare systems. Thus, we define how its role, its perception and its responsiveness manipulate the organization’s internal climate and shape the design of the performance monitoring systems. Our findings are expected to add knowledge on the reasons of the choice of adequate management systems, within three different healthcare organizational structures: university, general/university and general hospitals. [less ▲] Detailed reference viewed: 29 (2 ULg) Design of photochemical materials for carbohydrate production via the immobilisation of whole plant cells into a porous silica matrix; ; Léonard, Alexandre et alin Journal of Materials Chemistry (2010), 20(5), 929-936 Photochemical materials that act as bioreactors by exploiting the photosynthesis mechanism have been fabricated by entrapping whole plant cells within a porous silica matrix. The immobilisation step has ... [more ▼] Photochemical materials that act as bioreactors by exploiting the photosynthesis mechanism have been fabricated by entrapping whole plant cells within a porous silica matrix. The immobilisation step has been achieved via the in situ co-polymerisation of an aqueous silica precursor and a biocompatible trifunctional silane directly around cells. The cells remain undivided whilst the photochemical activity of the cells is well preserved over time. The design of a photochemical material that can act like a leaf, converting water into O2 and produce valuable organic compounds from CO2 under light irradiation is described. In particular, the increased excretion of polysaccharides by this photochemical material has been highlighted. The organic compounds formed have been extracted and analysed. The success of this work could open the door to new exciting photochemical materials with long-term photosynthetic activity and stability and to new green chemical processes for the conversion of solar energy into chemical energy with a concomitant reduction in CO2. © 2010 The Royal Society of Chemistry. [less ▲] Detailed reference viewed: 1 (0 ULg) Design of Photoreactive Orthosteric GABAA Ligands Potentially Useful for Studying Localization and Function of GABAA ReceptorsFrancotte, Pierre ; ; et alPoster (2011, May 08) Detailed reference viewed: 1 (0 ULg) Design of polymer blend rheology: 4. Effect of polymethacrylic ionomers on the melt viscosity of polyamide m x D,6; ; et al in Polymer (1997), 38(15), 3861-3867 Rheological properties of blends of polyamide m x D,6 (PA) with random copolymers of methyl methacrylate and methacrylic acid (P(MMA-co-MAA)) and the related ionomers (P(MMA-co-metal MA)), respectively ... [more ▼] Rheological properties of blends of polyamide m x D,6 (PA) with random copolymers of methyl methacrylate and methacrylic acid (P(MMA-co-MAA)) and the related ionomers (P(MMA-co-metal MA)), respectively, have been investigated at 260°C. Addition of small amounts of suitable ionomers (up to 5 wt%) remarkably increases the melt viscosity of PA. At low shear rates and depending on the metal cation of the ionomer, the rheofluidity of PA is reduced by at least two orders of magnitude. The PA melt viscosity increases with the cation as follows: Ni2+ < Ba2+ < Mg2+ < Li+ < Na+ < K+ < Cs+. The major effect is believed to occur when the polymer compatibility is improved to the point where a finely dispersed two-phase system with a low interfacial tension is reached, as a result of strong ion-dipole interactions. Polyblends show a rheothinning behaviour which agrees with the reversibility of H-bonding and dipolar interactions. [less ▲] Detailed reference viewed: 32 (2 ULg) Design of polymers by cobalt-mediated radical polymerization and coupling reactionDebuigne, Antoine ; Hurtgen, Marie ; Jérôme, Christine et alConference (2010, July 19) Detailed reference viewed: 14 (3 ULg) Design of reversibly core cross-linked micelles sensitive to reductive environmentCajot, Sébastien ; ; et alin Journal of Controlled Release (2011), 152(1), 30-36 Azido-functional amphiphilic macromolecules based on a biodegradable aliphatic polyester (poly-epsilon-caprolactone, PCL) and a bioeliminable hydrophilic poly(ethylene oxide) (PEO) block have been used in ... [more ▼] Azido-functional amphiphilic macromolecules based on a biodegradable aliphatic polyester (poly-epsilon-caprolactone, PCL) and a bioeliminable hydrophilic poly(ethylene oxide) (PEO) block have been used in order to build micellar drug delivery systems. Such azido groups being able to react by alkyne-azide 1,3 Huisgens cycloaddition (a click reaction) have been used further in order to cross-link the micelles via redox-sensitive disulfide bridges. This reversible cross-linking allows to prevent micelles dissociation at high dilution upon injection and to trigger their dissociation in more reductive environment, such as the cytosol. Copolymers having three different architectures, i.e. able to crosslink either the core or the shell of core-shell-corona system have been used to investigate their micellization, cross-linking and cross-linking reversibility. The stealthiness of these micelles crosslinked in the hydrophobic segment has also been studied in vitro. [less ▲] Detailed reference viewed: 60 (25 ULg) Design of reversibly disulfide core cross-linked polymer micellesCajot, Sébastien ; Schol, Daureen ; et alPoster (2011, November 21) Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block ... [more ▼] Over the last decade, polymer micelles attracted an increasing interest in drug pharmaceutical research because they could be used as efficient drug delivery systems. Micelles of amphiphilic block copolymers are supramolecular core-shell type assemblies of tens of nanometers in diameter. An accumulation of polymer nanocarriers to solid tumours is possible due to the EPR effect. Even if micelles get a high stability in aqueous media, the dissociation of micelles is not always preserved when they are injected in the blood compartment. This work aims at reporting on the design of reversibly cross-linked micelles based on PEO-b-PCL copolymers by introducing disulfide bridges in the micelle core to provide higher stability. Different kinds of macromolecular architectures are employed to study their impact on the micelles and their biological behavior. These new functional copolymers were all successfully micellized, reversibly cross-linked and are stealthy, which show the efficiency of the developed cross-linking process and offer a set of nanocarriers to be tested further, as shown on the first biological tests. [less ▲] Detailed reference viewed: 22 (4 ULg) Design of reversibly disulfide core cross-linked polymer micellesCajot, Sébastien ; Schol, Daureen ; et alPoster (2011, December 07) Detailed reference viewed: 17 (8 ULg) Design of River Navigation weirs and Flood Protection BarriersRigo, Philippe ; ; Herbillon, Vincent et alin 78th ICOLD Annual Meeting - Hanoi 2010 (2010, May 23) The aim of the WG (Working Group) was to conduct a comprehensive review (state-of-the-art) of the modern technologies, design tools and recent research used to design and build structures controlling ... [more ▼] The aim of the WG (Working Group) was to conduct a comprehensive review (state-of-the-art) of the modern technologies, design tools and recent research used to design and build structures controlling water level and flow in rivers, waterways and ports (for navigation & flood protection). The WG considered regulatory structures such as: - Gates controlling water level and flow in rivers (even non navigable) and waterways (lifting gate, tilting gate, radial gate, sector, etc.; designed in one piece or with an upper flap). These are referred to as WEIRS. - Gates controlling water level and flow in estuaries with regards to high tides and storms (lifting gate, articulated, tilting, rolling, floating, sliding, etc.). These structures are referred to as BARRIERS. [less ▲] Detailed reference viewed: 126 (6 ULg) Design of smart polymer micelles for pH triggered drug delivery systemsJérôme, Christine ![]() Conference (2009, April 02) Detailed reference viewed: 17 (6 ULg) Design of smart SPM probes by electrograftingGabriel, Sabine ; Jérôme, Christine ; Duwez, Anne-Sophie ![]() Conference (2007, May 11) Detailed reference viewed: 14 (2 ULg) Design of statistical measures for the assessment of image segmentation schemesVan Droogenbroeck, Marc ; Barnich, Olivier ![]() in Lecture Notes in Computer Science (2005), 3691 Image segmentation is discussed for years in numerous papers, but assessing its quality is mainly dealt with in recent works. Quality assessment is a primary concern for anyone working towards better ... [more ▼] Image segmentation is discussed for years in numerous papers, but assessing its quality is mainly dealt with in recent works. Quality assessment is a primary concern for anyone working towards better segmentation tools. It both helps to objectively improve segmentation techniques and to compare performances with respect to other similar algorithms. In this paper we use a statistical framework to propose statistical measures capable to describe the performances of a segmentation scheme. All the measures rely on a ground-truth segmentation map that is supposed to be known and that serves as a reference when qualifying the results of any segmentation tool. We derive the analytical expression of several transition probabilities and show how to calculate them. An important conclusion from our study, often overlooked, is that performances can be content dependent, which means that one should adapt a measure to the content of an image. [less ▲] Detailed reference viewed: 217 (10 ULg) Design of stealth nanoparticles for drug delivery based on new amphiphilic copolymersRieger, Jutta ; ; et alConference (2006, May 18) Detailed reference viewed: 29 (1 ULg) Design of Steel Connections according ENV 1993-1Jaspart, Jean-Pierre ![]() in Proceedings of the 15th IABSE Congress on Structural Engineering (1996) Detailed reference viewed: 7 (0 ULg) Design of steel connections according ENV 1993-1Jaspart, Jean-Pierre ![]() in Proceedings of the IABSE Congress on Structural Engineering in Consideration of Economy, Environment, Energy, Workshop on Structural Connections and Assembly Techniques (1996) Detailed reference viewed: 23 (0 ULg) Design of steel I-girders in bending and shear stiffened by one or two trapezoidal longitudinal stiffeners; Degée, Hervé ; Maquoi, René et alin Proceedings of the 5th Conference on Advances in Steel Structures (2007) Present paper focuses on the design of stiffened plates under bending and shear that are used in steel or composite bridges. Special attention is paid to situations involving one or two stiffeners, where ... [more ▼] Present paper focuses on the design of stiffened plates under bending and shear that are used in steel or composite bridges. Special attention is paid to situations involving one or two stiffeners, where Eurocode 3 Part 1.5 provides specific rules. First, the paper describes briefly the FEM numerical models used in parametric studies. Then, comparisons between results obtained respectively from numerical simulations and from application of the code clauses are presented. Also, some proposals for improved rules are made. [less ▲] Detailed reference viewed: 29 (1 ULg) Design of Steel Structures subjected to Fire. Background and Design Guide to Eurocode 3.Franssen, Jean-Marc ; Book published by Les Éditions de l'Université de Liège (2005) The information that is necessary to perform the fire design of a structure made of a particular material, say a steel structure, is: a) The bases of design, stated in EN 1990. b) The mechanical actions ... [more ▼] The information that is necessary to perform the fire design of a structure made of a particular material, say a steel structure, is: a) The bases of design, stated in EN 1990. b) The mechanical actions, i.e. the forces, acting on the structure in the fire situation. Some information is found in EN 1991-1-2, but explicit reference is also made to EN 1991-1-1 that is therefore also necessary. c) The thermal actions, i.e. the fire and the heat flux induced in the elements by the fire. The information is in EN 1991-1-2. d) The rules for determining the temperatures in the structure during the course of the fire. They are given in the fire part of the relevant material eurocode, e.g. EN 1993-1-2 for a steel structure. e) The rules for determining the structural stability. They are given in the fire part of the relevant material Eurocode, e.g. EN 1993-1-2 for a steel structure, but reference is often made to the cold part of the same material Eurocode, EN 1993-1-1 for a steel structure. This layout is valid in general but some exceptions do exist: the structural stability of timber elements, for example, does not necessarily require the determination of the temperatures in the element and step d) may be omitted; the same holds if the fire resistance is determined from tabulated data, for concrete elements for example. The rest of this book is organised according to this layout, see Fig. 1-2: Chapter 2 deals with bases of design and mechanical loads. Chapter 3 deals with thermal attack from the fire. Chapter 4 deals with thermal analysis by simple calculation model. Chapter 5 deals with mechanical analysis by simple calculation model. Chapter 6 deals with the design of joints. Chapter 7 deals with thermal and mechanical analysis by the advanced calculation model. Chapter 8 gives four design examples showing how a complete and sometimes complex structure can be designed using the concept of element or substructure analysis. [less ▲] Detailed reference viewed: 131 (2 ULg) Design of Steel Structures according to the General Model of Eurocode 3Franssen, Jean-Marc ![]() Scientific conference (2003, April 25) Detailed reference viewed: 14 (0 ULg) Design of Steel Structures subjected to Fire. Background and Design Guide to Eurocode 3. 2nd éditionFranssen, Jean-Marc ; Book published by Les édtions de l'Université de Liège (2006) The information that is necessary to perform the fire design of a structure made of a particular material, say a steel structure, is: a) The bases of design, stated in EN 1990. b) The mechanical actions ... [more ▼] The information that is necessary to perform the fire design of a structure made of a particular material, say a steel structure, is: a) The bases of design, stated in EN 1990. b) The mechanical actions, i.e. the forces, acting on the structure in the fire situation. Some information is found in EN 1991-1-2, but explicit reference is also made to EN 1991-1-1 that is therefore also necessary. c) The thermal actions, i.e. the fire and the heat flux induced in the elements by the fire. The information is in EN 1991-1-2. d) The rules for determining the temperatures in the structure during the course of the fire. They are given in the fire part of the relevant material eurocode, e.g. EN 1993-1-2 for a steel structure. e) The rules for determining the structural stability. They are given in the fire part of the relevant material Eurocode, e.g. EN 1993-1-2 for a steel structure, but reference is often made to the cold part of the same material Eurocode, EN 1993-1-1 for a steel structure. This layout is valid in general but some exceptions do exist: the structural stability of timber elements, for example, does not necessarily require the determination of the temperatures in the element and step d) may be omitted; the same holds if the fire resistance is determined from tabulated data, for concrete elements for example. The rest of this book is organised according to this layout, see Fig. 1-2: Chapter 2 deals with bases of design and mechanical loads. Chapter 3 deals with thermal attack from the fire. Chapter 4 deals with thermal analysis by simple calculation model. Chapter 5 deals with mechanical analysis by simple calculation model. Chapter 6 deals with the design of joints. Chapter 7 deals with thermal and mechanical analysis by the advanced calculation model. Chapter 8 gives four design examples showing how a complete and sometimes complex structure can be designed using the concept of element or substructure analysis. [less ▲] Detailed reference viewed: 89 (1 ULg) |
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