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See detailConsultations in molecular diagnostics - A case of FIP1L1-PDGFRA-positive chronic eosinophilic leukemia with a rare FIP1L1 breakpoint
Lambert, Frédéric ULg; Heimann, Pierre; Herens, Christian ULg et al

in Journal of Molecular Diagnostics (2007), 9(3), 414-419

The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HES and the related chronic eosinophilic leukemia (CEL) relied on ... [more ▼]

The idiopathic hypereosinophilic syndrome (HES) has remained for a long time a diagnosis of exclusion. Differential diagnosis between the HES and the related chronic eosinophilic leukemia (CEL) relied on the identification of signs of clonality that allowed, when present, the reclassification of patients as CEL. Recently, a new acquired mutation was described in approximately 50% of the HES/CEL patients: a cryptic deletion on chromosome band 4q12 generating a FIP1IL1-PDGFRA fusion gene. According to the World Health Organization classification, this clonal abnormality has been proposed as a new surrogate marker for chronic eosinophilic leukemia diagnosis. Fluorescence in situ hybridization and reverse transcriptase-polymerase chain reaction protocols were developed for an accurate del(4)(q12q12) and FIP1L1-PDGFRA fusion gene detection. Here, we report a patient with a rare FIP1L1 intron 16 breakpoint located outside of the reported FIP1L1 breakpoint region (ie, from FIP1L1 introns 9 to 13). This case illustrates the risk of false-negative results with diagnostic procedures that do not take into account the occurrence of rare FIP1L1 breakpoints. As targeted therapy with tyrosine kinase inhibitors has dramatically changed the prognosis of FIP1L1-PDGFRA (+) CEL, false-negative results could hamper accurate diagnosis and treatment. [less ▲]

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See detailConsumer acceptance of insect-based meat substitutes
Caparros Megido, Rudy ULg; Gierts, Chloé; Blecker, Christophe ULg et al

Conference (2014)

Meat plays an important role in the consumption pattern of most European and North American consumers. Meat production is responsible for a well known environmental pressure due to the inefficient ... [more ▼]

Meat plays an important role in the consumption pattern of most European and North American consumers. Meat production is responsible for a well known environmental pressure due to the inefficient conversion of plant protein to meat protein and alternatives sources, such as insects or algae, will be rapidly required. In a recent theorical study, de Boer et al. (2013) show that consumers prefer to eat a hybrid meat product (i.e. a mix of meat and its substitute) rather than a pure meat substitute [3]. Based on these preliminary results, hedonic tests were realized to assess the acceptability of insect-based burgers in a target population composed of people from 15 to 25 years old, considered as the future insect consumers. Isolated in a tasting booth, each participant was invited to taste four burger samples containing a ratio of 20 gr of protein by 100 gr of burger. The first burger was prepared with 95% of grounded beef (1), the second with 95% of green lentil (2), the third with 45% of green lentil and 50% of mealworms (Tenebrio molitor L.; Coleoptera, Tenebrionidae) and the fourth with 45% of grounded beef burger and 50% of mealworms. The last 5% of each burger consists of an aromatization portion containing onions, carrots, tomato paste and garlic. Participants were asked to rate each sample on a 9-point hedonic scale, where extreme sides were noted from “extremely dislike” (left) to “extremely like” (right). Tukey post-hoc comparisons on the appreciation results showed that beef-based products (with or without mealworms) were relatively preferred to lentil-based products (with or without mealworms), probably because hybrid meat burgers seem more familiar to the consumers than vegetable burgers, and that no liking differences were noticed between the two beef-based burgers and between the two insect-based burgers. These results confirm that shape and appearance are key criteria in the acceptation of meat substitute by non-vegetarian consumers and that insects will preferentially be consumed, in the future, if they are presented in an invisible way and associated with familiar flavors. [less ▲]

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See detailConsumer Evaluations of Brand Extensions: Differences between Goods and Services
Van Riel, Allard ULg; Lemmink, Jos; Ouwersloot, Hans

in Journal of Service Research (2001), 3(3), 220-231

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See detailConsumer valuation of improved rice parboiling technologies in Benin
Matty, Demont; Zossou, Enangnon ULg; Pieter, Rutsaert et al

in Food Quality & Preference (2012), 23(1), 63-70

In Benin, traditional parboiling is still widely practiced among rice processors, resulting in inferior grain quality. A new parboiler was introduced to improve the milling yield and intrinsic quality of ... [more ▼]

In Benin, traditional parboiling is still widely practiced among rice processors, resulting in inferior grain quality. A new parboiler was introduced to improve the milling yield and intrinsic quality of local rice. We conducted Vickrey second price auctions to elicit rural Beninese consumers’ willingness to pay for rice obtained through the new parboiler and two locally innovated parboilers. The individual auctions were followed by a group discussion during which consensus was reached on socially acceptable prices. Relative to traditionally parboiled rice, consumers were willing to pay price premiums of 9–13% for rice obtained through a local parboiler using a container of which the bottom is a perforated metal, 27% for rice obtained through a local parboiler using wooden sticks at the bottom of the pot, and 25–34% for rice parboiled through the improved parboiler. Bids were influenced by the presentation order of the products according to perceived quality. Bids were also higher when participants had been informed on the benefits of improved parboiling techniques, which is a crucial insight for developing marketing and communication strategies for this improved quality product. Group bids were not significantly different from individual bids which suggests that the latter are within the range of socially acceptable prices defined through group consensus. [less ▲]

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See detailConsumption of Immature Stages of Colorado Potato Beetle by Chrysoperla Carnea (Neuroptera: Chrysopidae) Larvae in the Laboratory
Sablon, Ludovic ULg; Haubruge, Eric ULg; Verheggen, François ULg

in American Journal of Potato Research (2013), 90(1), 51-57

The Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say), has been an important defoliator of potatoes for 150 years. Although the use of insecticides allowed drastic reductions of CPB ... [more ▼]

The Colorado potato beetle (CPB), Leptinotarsa decemlineata (Say), has been an important defoliator of potatoes for 150 years. Although the use of insecticides allowed drastic reductions of CPB populations, resistance development against active substances has been observed. In this context, biological control using predatory larvae of the lacewing may represent a good alternative. CPB egg and larval consumption rates have been evaluated for all Chrysoperla carnea (Stephens) instars for 24 h. While first and second C. carnea instars only consumed eggs (1.3 and 1.8), first (1.5 and 2.4) and second (0.6 and 0.8) CPB instars, third instar of lacewing consumed all CPB immature stages: 6.8 CPB eggs, 8.5 first, 4 s, 0.5 third and 0.1 fourth CPB instars. This third instar killed 4-fold more CPB larvae than other larval stages. Handling time for third instar lacewing has been evaluated at 52 min on first instar CPB, 102 min on second instar and 164 min on third instar. Our laboratory assays highlight a potential for lacewing larvae to control CPB immature stages with a greater efficiency on young CPB larval stages. Fields assays are however needed to confirm efficiency of this CPB natural enemy under field conditions. [less ▲]

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See detailConsumptive and nonconsumptive effects of cannibalism in fluctuating age-structured populations
Wissinger, Scott A.; Whiteman, Howard H.; Denoël, Mathieu ULg et al

in Ecology (2010), 91(2), 549-599

Theory and empirical studies suggest that cannibalism in age-structured populations can regulate recruitment depending on the intensity of intraspecific competition between cannibals and victims and the ... [more ▼]

Theory and empirical studies suggest that cannibalism in age-structured populations can regulate recruitment depending on the intensity of intraspecific competition between cannibals and victims and the nature of the cannibalism window, i.e., which size classes interact as cannibals and victims. Here we report on a series of experiments that quantify that window for age-structured populations of salamander larvae and paedomorphic adults. We determined body size limits on cannibalism in microcosms and then the consumptive and nonconsumptive (injuries, foraging and activity, diet, growth) effects on victims in mesocosms with seminatural levels of habitat complexity and alternative prey. We found that cannibalism by the largest size classes (paedomorphs and >age 3+yr larvae) occurs mainly on young-of-the-year (YOY) victims. Surviving YOY and other small larvae had increased injuries, reduced activity levels, and reduced growth rates in the presence of cannibals. Data on YOY survival in an experiment in which we manipulated the density of paedomorphs combined with historical data on the number of cannibals in natural populations indicate that dominant cohorts of paedomorphs can cause observed recruitment failures. Dietary data indicate that ontogenetic shifts in diet should preclude strong intraspecific competition between YOY and cannibals in this species. Thus our results are consistent with previous empirical and theoretical work that suggests that recruitment regulation by cannibalism is most likely when YOY are vulnerable to cannibalism, but have low dietary overlap with cannibals. Understanding the role of cannibalism in regulating recruitment in salamander populations is timely given the widespread occurrences of amphibian decline. Previous studies have focused on extrinsic (including anthropogenic) factors that affect amphibian population dynamics, whereas the data presented here combined with long-term field observations suggest the potential for intrinsically driven population cycles. [less ▲]

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See detailConsumpton as a Solidarity-based Commitment : The Case of Oxfam Worldshops' Customers
Pirotte, Gautier ULg

in Zaccaï, Edwin (Ed.) Sustainable consumption: What Role for Consumers? Ecology and Fair Trade (2007)

Detailed reference viewed: 29 (4 ULg)
See detailThe Contact & the Culmination : Essays in Honour of Hena Maes-Jelinek
Delrez, Marc ULg; Ledent, Bénédicte ULg

Book published by Liège Language and Literature (L3) (1997)

Detailed reference viewed: 36 (18 ULg)
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See detailContact Algorithms for Numerical Modeling of Tribological Devices
CHABRAND, P.; DUBOIS, F.; GRAILLET, D. et al

in Proceedings of "First ESAFORM Conference on Material Forming (1998)

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See detailContact and photocontact allergy to ketoprofen. The Belgian experience.
Matthieu, L.; Meuleman, L.; Van Hecke, E. et al

in Contact Dermatitis (2004), 50(4), 238-241

Topical ketoprofen (KP) is widely used because of its anti-inflammatory effect. However, photocontact dermatitis is a side-effect. Between May 2001 and June 2002, the Belgian Contact & Environmental ... [more ▼]

Topical ketoprofen (KP) is widely used because of its anti-inflammatory effect. However, photocontact dermatitis is a side-effect. Between May 2001 and June 2002, the Belgian Contact & Environmental Dermatitis Group conducted a prospective, open patch and photopatch test study in 20 patients suspected of KP dermatitis. Severe skin symptoms requiring systemic corticotherapy occurred in 47%. 5 patients were hospitalized. 1 patient showed prolonged photosensitivity. All patients were tested with KP and the other constituents of KP gel. Attribution to KP was demonstrated in all cases. Patch and photopatch tests with KP 2% in petrolatum showed contact photoallergy in 17 patients, contact allergy in 1 patient and photoaggravated contact allergy in 2 patients. 5 patients also reacted to the fragrance components lavender (Lavandula augustifolia) oil and/or neroli (Citrus aurantium dulcis) oil 5% in alcohol. However, in 4 of these, irritant reactions to the ethanolic dilutions could not be ruled out. Additional tests with 3 non-steroidal anti-inflammatory drugs without benzophenone structure ibuprofen, naproxen and diclofenac identified only 1 contact allergic reaction to diclofenac. Cross-reactivity to the substituted benzophenones, oxybenzone and sulisobenzone occurred only to the first in less than 30% of the patients. A high frequency (69%) of contact allergy to fragrance mix was found. Dermatologists should be aware of the severity of photoallergic reactions to KP and the risk of cross-sensitization. [less ▲]

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See detailContact between deformable solids, the fully coupled approach
Habraken, Anne ULg; Cescotto, Serge ULg

in Mathematical & Computer Modelling (1998), 28(4-8), 153-169

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See detailContact center as new forms of work organization: the triangular relationship between worker, contact center and contractors and well-being at work
DE CIA, Julie ULg; Naedenoen, Frédéric ULg; Pichault, François ULg et al

Conference (2013, May)

Purpose The new forms of work organization are characterized by different evolutions: multiple workers status, fragmentation of collective work, etc. Among these evolutions, the triangular relationship ... [more ▼]

Purpose The new forms of work organization are characterized by different evolutions: multiple workers status, fragmentation of collective work, etc. Among these evolutions, the triangular relationship between worker, employer and contractors and the intervention of contractors in work organization (Marchington et al., 2004) may be particularly affecting the well-being of workers. This research focus on contact center as a new form of work organization to investigate the influence of the triangular employment relationship on well-being at work. Methodology A quantitative and qualitative approach was used. A survey based on Job Demand-Resources Model (Bakker, Demerouti & Schaufeli, 2003) was conducted among 400 operators from Belgian contact centers to compare internal, outsourced and external contact centers. Three case studies allowed exploring more deeply the influence of triangular employment relationship on well-being. Finally, focus-groups with unions and management representatives helped us to design some practical recommendations. Results Quantitative results indicate that operators from outsourced and external contact centers have a poorer perception of demands and resources at work. They are consequently more likely to report high levels of perceived stress and burnout and low satisfaction with their work. The case studies give us more information about the role of the strategy and the management style of contact centers in coping with triangular employment relationships. Limitations Beyond this explorative research, quantitative data can be further used in multi-sample modeling approach. Research/Practical Implications Recommendations for well-being at work regarding the triangular employment relationship, on which both employers and unions converge, will be highlighted at the conference. Originality This research combines organizational psychology and management theory. [less ▲]

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See detailContact model between superelements in dynamic multibody systems
Virlez, Geoffrey ULg; Bruls, Olivier ULg; Sonneville, Valentin ULg et al

in Proceedings of ASME2013 International Design Engineering Technical Conference & Computers and Information in Engineering Conference IDETC/CIE 2013 (2013, August)

In this paper, a new contact formulation defined between flexible bodies modeled as superelements is investigated. Unlike rigid contact models, this approach enables to study the deformation and vibration ... [more ▼]

In this paper, a new contact formulation defined between flexible bodies modeled as superelements is investigated. Unlike rigid contact models, this approach enables to study the deformation and vibration phenomena induced by hard contacts. Compared with full-scale finite element models of flexible bodies, the proposed method is computationally more efficient, especially in case of a large number of bodies and contact conditions. The compliance of each body is described using a reduced-order elastic model which is defined in a corotational frame that follows the gross motion of the body. The basis used to reduce the initial finite element model relies on the Craig-Bampton method which uses both static boundary modes and internal vibration modes. The formulation of the contact condition couples all degrees of freedom of the reduced model in a nonlinear way. The relevance of the approach is demonstrated by simulation results first on a simple example, and then on a gear pair model. [less ▲]

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See detailContact-killing polyelectrolyte microcapsules based on chitosan derivatives
Cui, Di; Szarpak, Anna; Pignot-Paintrand, Isabelle et al

in Advanced Functional Materials (2010), 20(19), 3303-3312

A new type of multilayer capsules is designed for use as antibacterial vehicles by taking advantage of the properties of natural polysaccharides. These capsules, prepared by layer-by-layer assembly of ... [more ▼]

A new type of multilayer capsules is designed for use as antibacterial vehicles by taking advantage of the properties of natural polysaccharides. These capsules, prepared by layer-by-layer assembly of hyaluronic acid (HA; see graphic) and quaternized chitosan (QCHI) derivatives onto sacrificial colloidal particles, show distinct killing activities depending on the nature of the polysaccharide on the surface. [less ▲]

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See detailA contactin-receptor-like protein tyrosine phosphatase beta complex mediates adhesive communication between astroglial cells and gonadotropin-releasing hormone neurons
Parent, Anne-Simone ULg; Mungenast, Alison; Lomniczi, Alejandro et al

in Journal of Neuroendocrinology (2007), 19

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See detailContagion inside the Credit Default Swaps markets in the light of 2008 crisis
Sougné, Danielle ULg; Mattar, Jamal ULg

in Journal of Business and Economics (2012)

Detailed reference viewed: 94 (10 ULg)
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See detailThe containment strategy of extreme right wing parties : a failure ?
Italiano, Patrick ULg; Pieters, Jérôme ULg; Kovincic, Petar ULg et al

Conference (2012, November)

When confronted to data from European social Survey, there seems to be no link between the acceptance of immigration by public opinion in a sample of western Europe countries and the presence of extreme ... [more ▼]

When confronted to data from European social Survey, there seems to be no link between the acceptance of immigration by public opinion in a sample of western Europe countries and the presence of extreme right parties in those countries. This contradicts various political analysis and some other data. The paper states this possible discrepancy and tries to find explanations [less ▲]

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See detailUn contaminant envahissant : nouveau regard sur le thigmotropisme fongique.
Quatresooz, Pascale; Blaise, Géraldine; Henry, Frédérique ULg et al

in Dermatologie Actualité (2008), 107

Detailed reference viewed: 50 (8 ULg)