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Peer Reviewed
See detailCellular and molecular aspects of thymic T-cell education to neurohypophysial peptides
Geenen, Vincent ULg; Martens, Henri ULg; Vandersmissen, Eric et al

in Excerpta Medica (1995), 1098

Detailed reference viewed: 8 (1 ULg)
See detailCellular and molecular evidence for an evolutionary continuum of neuroendocrine-immune interactions
Geenen, Vincent ULg

Conference given outside the academic context (1994)

Detailed reference viewed: 5 (0 ULg)
Peer Reviewed
See detailCellular and molecular mechanisms involved in thymic T-cell education to neuroendocrine self principles
Geenen, Vincent ULg; Benhida, Abdellah; Kecha, Ouafae et al

in International Journal of Thymology (1996), 4

Detailed reference viewed: 13 (1 ULg)
Peer Reviewed
See detailCellular and nervous environment of mouse mesenteric lymph node germinal centres
Wenders, Frédéric ULg; Dorban, G.; Piret, Joëlle ULg et al

Conference (2005, April)

Detailed reference viewed: 23 (0 ULg)
Peer Reviewed
See detailCellular Aspects of the Pathogenesis of Radiation--Induced Thymic Lymphomas in C57 Bl Mice (Review)
Boniver, Jacques ULg; Humblet, Chantal ULg; Rongy, A. M. et al

in In Vivo (Athens, Greece) (1990), 4(1, Jan-Feb), 41-3

Radiation-induced thymic lymphomas in C57Bl/Ka mice are interesting models for studying the successive steps of carcinogenesis. Irradiation initiates "preleukemic" cells, which are promoted to become ... [more ▼]

Radiation-induced thymic lymphomas in C57Bl/Ka mice are interesting models for studying the successive steps of carcinogenesis. Irradiation initiates "preleukemic" cells, which are promoted to become neoplastic. Studies in mice in which lymphoma development is inhibited by a bone marrow transplantation after irradiation suggest that radiation--induced alterations to the T cell lineage, and particularly to thymic microenvironment, are critical for the promotion of preleukemic cells. It is proposed that the lack of physiological differentiation signals within the thymus, as a result of irradiation, allows these cells to escape the normal controls of thymocyte production and pushes them towards neoplastic transformation. A disturbance in the production of cytokines may be involved, since exogenous cytokines, such as Interferon gamma or Tumor Necrosis Factor a, can inhibit radiation-induced lymphomagenesis, reproducing the effects of bone marrow transplantation. The model is thus suitable for studying the mechanisms of carcinogenesis and designing biological manipulation devoted to cancer prevention in individuals who have been exposed to oncogenic agents. [less ▲]

Detailed reference viewed: 37 (3 ULg)
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Peer Reviewed
See detailCellular automata urban expansion model based on support vector machines
El Saeid Mustafa, Ahmed Mohamed ULg; Rienow, Andreas; Saadi, Ismaïl ULg et al

in Mostafavi, Mir‐Abolfazl; Pinto, Nuno (Eds.) PROCEEDINGS of Second International Symposium on Cellular Automata Modeling for Urban and Spatial Systems (2016, October 30)

Land-use change models are used to explore the dynamics and drivers of land-use/landcover change and to inform policies affecting such change. A broad array of applications and modeling methods are ... [more ▼]

Land-use change models are used to explore the dynamics and drivers of land-use/landcover change and to inform policies affecting such change. A broad array of applications and modeling methods are available and each type has certain advantages and disadvantages depending on the objective of the research. This work presents an approach combining cellular automata (CA) model and supported vector machine (SVM) and binary logistic regression model (Logit) for simulating urban expansion in Wallonia (Belgium). This article emphasizes the interest in comparing combining CA with conventional Logit versus combining CA with SVM method as a base of CA model transition rule. Relative operating characteristic (ROC) and spatial matrices are used to validate the model. Model validation shows that the allocation performance of CA-SVM outperformed CALogit approach. [less ▲]

Detailed reference viewed: 33 (5 ULg)
Peer Reviewed
See detailCellular composition of bronchial brushings obtained from dogs with experimental chronic bronchitis
Bolognin, M.; Tual, Charlotte ULg; Day, M. J. et al

in 18th ECVIM Meeting - Gent - Belgique - 2-5 septembre 2008 (2008, September 02)

Detailed reference viewed: 11 (0 ULg)
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Peer Reviewed
See detailCellular context regulates magnitude and direction of Ets-mediated transcriptional regulation of collagen
Czuwara-Ladykowska, Joanna; Shirasaki, Fumiaki; Jackers, Pascale ULg et al

Poster (2000, December 09)

Detailed reference viewed: 10 (4 ULg)
See detailCellular distribution of NSP in normal pituitary and in pituitary adenomas. Comparison with pituitary hormone expression.
Dukers, N.; Senden, N.; Timmer, E. et al

in 4th Euregional oncology meeting - abstract book (1997)

Detailed reference viewed: 4 (1 ULg)
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Peer Reviewed
See detailCellular engineering of Bacillus subtilis to enhance the biosynthesis of highly active anti fungal lipopeptides
Guy, J.; Guez, Jean-Sébastien; Coucheny, F. et al

Poster (2010)

Detailed reference viewed: 14 (4 ULg)
Peer Reviewed
See detailCellular Events in Radiation-Induced Lymphomagenesis
Boniver, Jacques ULg; Humblet, Chantal ULg; Rongy, A. M. et al

in International Journal of Radiation Biology (1990), 57(4), 693-8

Fractionated whole-body irradiation induces thymic lymphomas in most of treated C57Bl/Ka mice. The cellular events occurring during the latency period consist of the emergence of preleukaemic cells and of ... [more ▼]

Fractionated whole-body irradiation induces thymic lymphomas in most of treated C57Bl/Ka mice. The cellular events occurring during the latency period consist of the emergence of preleukaemic cells and of marked alterations to the T-cell lineage and the microenvironment within the thymus. The proportions of the various thymocyte subsets are modified, suggesting a blockage in the normal differentiation process. Thymic epithelial cells are functionally modified, leading to decreased interactions with immature thymocytes. Interestingly, bone marrow grafting early after irradiation, which inhibits the development of lymphomas, induces the disappearance of preleukaemic cells from the thymus, whereas thymocyte subpopulations and thymic epithelium are restored. Interferon gamma and tumor necrosis factor alpha also prevent the onset of lymphomas. Studies on the effect of bone marrow transplantation and cytokine inoculation in split-dose irradiated mice should allow characterization of the factors that modulate the progression of preleukaemic cells towards the neoplastic state. [less ▲]

Detailed reference viewed: 22 (3 ULg)
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Peer Reviewed
See detailCellular immunotherapy in multiple myeloma : lessons from preclinical models
Binsfeld, Marilène ULg; Fostier, K.; Muller, Joséphine ULg et al

in Biochimica et Biophysica Acta - Reviews on Cancer (2014), 1846

The majority of multiple myeloma patients relapse with the current treatment strategies, raising the need for alternative therapeutic approaches. Cellular immunotherapy is a rapidly evolving field and ... [more ▼]

The majority of multiple myeloma patients relapse with the current treatment strategies, raising the need for alternative therapeutic approaches. Cellular immunotherapy is a rapidly evolving field and currently being translated into clinical trials with encouraging results in several cancer types, including multiple myeloma. Murine multiple myeloma models are of critical importance for the development and refinement of cellular immunotherapy. In this review,we summarize the immune cell changes that occur inmultiplemyelomapatients and we discuss the cell-based immunotherapies that have been tested in multiple myeloma, with a focus on murine models. [less ▲]

Detailed reference viewed: 64 (10 ULg)
Peer Reviewed
See detailCellular localization of IGF-I and IGF-II mRNAs in immature hypophysectomized rat testis and epididymis after in vivo hormonal treatment.
Dombrowicz, D.; Hooghe-Peters, E. L.; GOTHOT, André ULg et al

in Archives internationales de physiologie, de biochimie et de biophysique (1992), 100(5), 303-8

IGF-I and II genes expression has been localized by in situ hybridization in testis and epididymis of immature hypophysectomized rats treated in vivo with either pFSH, hLH, bGH, hPRL or with saline. IGF-I ... [more ▼]

IGF-I and II genes expression has been localized by in situ hybridization in testis and epididymis of immature hypophysectomized rats treated in vivo with either pFSH, hLH, bGH, hPRL or with saline. IGF-I mRNA expression was found in both Sertoli and Leydig cells after treatment with either FSH or LH. IGF-I mRNA was highly expressed in germ cells after FSH stimulation and to a lesser extent after GH or LH treatments. However, its expression was very low in hypophysectomized control or PRL treated rats. IGF-I mRNA was also expressed in stromal cells of epididymis after LH treatment and to a lesser extent after GH stimulation. In contrast, IGF-II mRNA expression was detected in all testicular cell types whatever the hormonal treatment (FSH, LH, GH, PRL). For each hormonal treatment testicular sections were examined after immunohistochemical staining with specific antisera against IGF-I and IGF-II. Both in situ hybridization and immunohistochemical data were examined in order to determine the testicular sites of synthesis of IGF-I and IGF-II. [less ▲]

Detailed reference viewed: 13 (1 ULg)
See detailCellular mechanisms controlling rapid changes in brain aromatase activity
Charlier, Thierry; Cornil, Charlotte ULg; Ball, Gregory et al

in Balthazart, Jacques; Ball, Gregory (Eds.) Brain aromatase, estrogens and behavior (2012)

Detailed reference viewed: 18 (1 ULg)
Peer Reviewed
See detailCellular origin of HPV-related (pre)cancer
Herfs, Michael ULg

Conference (2016, May)

Detailed reference viewed: 18 (0 ULg)