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See detailChauve-souris des traditions d’Europe de l’Ouest : le vol sombre
Strivay, Lucienne ULg

Conference (2002, March 23)

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See detailLa chauve-souris et l’hirondelle, le lait et le sang.
Strivay, Lucienne ULg

in Dounias, Edmond; Motte-Florac, Elisabeth; Dunham, Margaret (Eds.) Animals, keystone in the relationship between Man and Nature (2007)

Detailed reference viewed: 52 (2 ULg)
See detailCheap Biofuels Expensive Food: Insights Gained with Global Balances
Pfennig, Andreas ULg

Conference (2009, September 21)

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See detailCheatgrass is favored by warming but not CO2 enrichment in a semi-arid grassland
Blumenthal, Dana; Kray, Julie; Ortmans, William ULg et al

in Global Change Biology (2016), Early view

Elevated CO2 and warming may alter terrestrial ecosystems by promoting invasive plants with strong community and ecosystem impacts. Invasive plant responses to elevated CO2 and warming are difficult to ... [more ▼]

Elevated CO2 and warming may alter terrestrial ecosystems by promoting invasive plants with strong community and ecosystem impacts. Invasive plant responses to elevated CO2 and warming are difficult to predict, however, because of the many mechanisms involved, including modification of phenology, physiology, and cycling of nitrogen and water. Understanding the relative and interactive importance of these processes requires multifactor experiments under realistic field conditions. Here, we test how free-air CO2 enrichment (to 600 ppmv) and infrared warming (+1.5 °C day/3 °C night) influence a functionally and phenologically distinct invasive plant in semi-arid mixed-grass prairie. Bromus tectorum (cheatgrass), a fast-growing Eurasian winter annual grass, increases fire frequency and reduces biological diversity across millions of hectares in western North America. Across 2 years, we found that warming more than tripled B. tectorum biomass and seed production, due to a combination of increased recruitment and increased growth. These results were observed with and without competition from native species, under wet and dry conditions (corresponding with tenfold differences in B. tectorum biomass), and despite the fact that warming reduced soil water. In contrast, elevated CO2 had little effect on B. tectorum invasion or soil water, while reducing soil and plant nitrogen (N). We conclude that (1) warming may expand B. tectorum's phenological niche, allowing it to more successfully colonize the extensive, invasion-resistant northern mixed-grass prairie, and (2) in ecosystems where elevated CO2 decreases N availability, CO2 may have limited effects on B. tectorum and other nitrophilic invasive species. [less ▲]

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See detailCHECK : Manuel d'utilisation
Denis, Brigitte ULg

Learning material (1994)

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See detailChecking the internal pedagogical consistency of a game learning situation: the Leclercq’s triple consistency triangle
Castaigne, J.-L.; Petit, L; Verpoorten, Dominique ULg

in Targamadze, A (Ed.) Proceedings of the Advanced Learning Technologies and Applications (ALTA) conference (2007, September 20)

Leclercq’s triangle is a conceptual tool used for securing the pedagogical validity of learning situations. It materializes the sound pedagogy principle which commands to establish a triple consistency ... [more ▼]

Leclercq’s triangle is a conceptual tool used for securing the pedagogical validity of learning situations. It materializes the sound pedagogy principle which commands to establish a triple consistency between objectives, methods and evaluation in any given learning situation. The ELEKTRA adventure game provides a practical illustration of its relevance. [less ▲]

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See detailChecklist of Aphidiinae (Hymenoptera: Braconidae) and Aphelinus (Hymenoptera: Aphelinidae) species from Belgium with respectively four and three new records
Chevalier Mendes Lopes, Thomas ULg; Libert, Pierre-Nicolas; Starý, Petr et al

in Zootaxa (2016), 4092(4)

Aphid parasitoids have good potential for crop protection. However, they have been poorly studied in Belgium, especially in terms of species diversity. Therefore, the aim of this work was to establish the ... [more ▼]

Aphid parasitoids have good potential for crop protection. However, they have been poorly studied in Belgium, especially in terms of species diversity. Therefore, the aim of this work was to establish the first checklist for the country. To complete the list, aphid parasitoids were sampled in wheat and pea fields near Gembloux (Belgium), in 2013 and 2014. Among the identified species, Aphelinus asychis Walker, Aphelinus daucicola Kurdjumov, Aphelinus fusciscapus (Förster), Aphidius asteris Haliday, Aphidius eadyi Starý, Gonzalez & Hall, Praon barbatum Mackauer, and Trioxys auctus (Haliday) were recorded for the first time in Belgium. Thirty-two Aphidiinae and seven Aphelinus species were included in the checklist. It is hoped this study will stimulate further research, as species diversity is still low compared with neighbouring countries. [less ▲]

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See detailA checklist of the bryophytes of Corsica (France): new records and a review of the literature
Sotiaux, André ULg; Pioli, A.; Royaud, A. et al

in Journal of Bryology (2007), 29(Part 1), 41-53

Based on a thorough review of the literature as well as floristic surveys undertaken over 20 years, a checklist of the bryophytes of Corsica, a mountainous western Mediterranean island, is presented. The ... [more ▼]

Based on a thorough review of the literature as well as floristic surveys undertaken over 20 years, a checklist of the bryophytes of Corsica, a mountainous western Mediterranean island, is presented. The occurrence of 17 liverwort and 44 moss species is documented for the first time from Corsica. As a result, the Corsican bryoflora includes 540 species: 148 liverworts, three hornworts and 389 mosses. Among the species reported, seven liverwort and 17 moss species are red-listed in Europe. By contrast with angiosperms, no bryophyte is endemic to the island based on traditional, phenetic species concepts. The number of new species reported here indicates that Corsica is exceedingly under-recorded bryologically. A better knowledge of the distribution, frequency and ecology of bryophyte species on the island is thus an absolute prerequisite in order to propose appropriate conservation measures in this Mediterranean environment that is, at least locally, severely threatened. [less ▲]

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See detailCheckpoints modulation by Human T-Lymphotropic Virus Type 1 (HTLV-1) Tax protein
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

Conference (2013, December 13)

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See detailCheckpoints modulation by the human T-lymphotropic virus type 1 (HTLV-1) Tax protein : towards new therapeutic approaches
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

Poster (2015, February 11)

HTLV-1 infects approximately 20 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is ... [more ▼]

HTLV-1 infects approximately 20 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is currently no satisfactory treatment for these diseases. Among the proteins encoded by HTLV-1, Tax appears to play an important role in the mechanisms leading to pathogenicity. We are interested in the mechanisms of cell transformation by HTLV-1 and more particularly in the interplay between the viral Tax oncoprotein and the DNA damage response (DDR). We demonstrate that transient expression of Tax results in DNA damage, cell cycle arrest and activation of the ATM-Chk2-p53 axis of the DDR. In fibroblasts, cell cycle arrest occurs at the G1 and G2 phases depending on the p53 background. Despite Tax expression hampers cell cycle progression, neither pro-apoptotic nor pro-senescent effects are observed. In contrast, HTLV-1 infected lymphocytes proliferate continuously and appear to be adapted to the checkpoints. This mechanism allows infected lymphocytes to proliferate despite the presence of genomic lesions. Those cells might thus rely on effective DNA repair mechanisms. Indeed, we show that Tax expressing cells activate the error free repair mechanism homologous recombination (HR). Inhibition of ATM, involved in DDR and DNA repair by HR, impedes Tax-mediated cellular transformation. Depending on these observations, we propose a novel therapeutic approach based on the principle of synthetic lethality. [less ▲]

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See detailCheckpoints modulation by the human T-lymphotropic virus type 1 (HTLV-1) Tax protein : towards new therapeutic approaches
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

Poster (2015, May 13)

HTLV-1 infects approximately 15 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is ... [more ▼]

HTLV-1 infects approximately 15 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is currently no satisfactory treatment for these diseases. Among the proteins encoded by HTLV-1, Tax appears to play an important role in the mechanisms leading to pathogenicity. We are interested in the mechanisms of cell transformation by the Tax viral oncoprotein. In particular, we aim at understanding the interplay between Tax and the DNA damage response (DDR). We show that transient expression of Tax results in DNA damage, cell cycle arrest and activation of the DDR. In fibroblasts, cell cycle arrest occurs at the G1 and G2 phases depending on the p53 background. In contrast, HTLV-1 infected lymphocytes proliferate continuously and appear to be adapted to the checkpoints. This mechanism of checkpoint adaptation thus allows ongoing proliferation despite the presence of genomic lesions. Quantification of the rates of NHEJ and homologous recombination indicates that HTLV-1 infected cells require very efficient DNA repair for survival. Therefore, we propose a novel therapeutic approach based on the principle of synthetic lethality using inhibitors of DNA repair. [less ▲]

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See detailCheckpoints modulation by the human T-lymphotropic virus type 1 (HTLV-1) Tax protein : towards new therapeutic approaches
Carpentier, Alexandre ULg; Willems, Luc

Poster (2012, June 22)

HTLV-1 infects approximately 20 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is ... [more ▼]

HTLV-1 infects approximately 20 million people worldwide and causes several diseases. This virus is responsible for the adult T-cell leukemia (ATL) and for a chronic neuropathology (TSP/HAM). There is currently no satisfactory treatment for these diseases. Among the proteins encoded by HTLV-1, Tax appears to play an important role in the mechanisms leading to pathogenicity. We are interested in the mechanisms of cell transformation by HTLV-1 and more particularly in the interplay between the viral Tax oncoprotein and the DNA damage response (DDR). We demonstrated that transient expression of Tax results in DNA damage, cell cycle arrest and activation of the ATM-Chk2-p53 axis of the DDR. In fibroblasts, cell cycle arrest occurs at the G1 and G2 phases depending on the p53 background. In contrast, HTLV-1 infected lymphocytes proliferate continuously and appear to be adapted to Chk2 and p53 checkpoints. This mechanism allows infected lymphocytes to proliferate despite the presence of genomic lesions. Our data shows that HTLV-1 infected cells use an alternative DNA repair pathway controlled by ATM and Chk1. This particularity may be used as novel therapeutic approach based on the principle of synthetic lethality. [less ▲]

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See detailCheckpoints modulation by the Human T-lymphotropic virus type 1 Tax protein
Carpentier, Alexandre ULg; Barez, Pierre-Yves ULg; Boxus, Mathieu et al

in Retrovirology (2014), 11(S1), 90

HTLV-1 is responsible for two main diseases, Adult T-cell Leukemia/Lymphoma and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis, for which there is currently no satisfactory treatment. Among the ... [more ▼]

HTLV-1 is responsible for two main diseases, Adult T-cell Leukemia/Lymphoma and HTLV-1 Associated Myelopathy/Tropical Spastic Paraparesis, for which there is currently no satisfactory treatment. Among the proteins encoded by HTLV-1, Tax appears to play an important role in the mechanisms leading to pathogenicity. We are interested in the mechanisms of cell transformation by Tax and more particularly in the interplay between the viral Tax oncoprotein and the DNA damage response (DDR). We demonstrated that transient expression of Tax results in DNA damage, cell cycle arrest and activation of the DDR. In fibroblasts, cell cycle arrest occurs at the G1 and G2 phases depending on the p53 background. Although Tax induces apoptosis and senescence in fibroblasts, HTLV-1 infected lymphocytes proliferate continuously and appear to be adapted to the checkpoint control. This mechanism allows infected lymphocytes to proliferate despite the presence of genomic lesions. With these observations, we propose a novel therapeutic approach based on the principle of synthetic lethality. [less ▲]

Detailed reference viewed: 68 (29 ULg)
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See detailLe "cheetah-look". Le phénotype guépart, face cachée de la pigmentation mélanique innée du visage.
Hermanns-Lê, Trinh ULg; AL RUSTOM, Kamil; FRANCHIMONT, Claudine ULg et al

in Dermatologie Actualité (2012), 131

Detailed reference viewed: 19 (3 ULg)
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See detail"Le chef de saint Jean Baptiste sur un plat", Jan van Steffeswert, 1508
Van den Bossche, Benoît ULg

in Delfosse, Annick; Glesener, Thomas (Eds.) Lire, écrire et éduquer à la Renaissance. Mélanges en l'honneur de Franz Bierlaire (2013)

Rédigé dès 2010 pour faire honneur au professeur Franz Bierlaire, cet article a été publié une première fois en 2012 sous une forme légèrement amendée à l'occasion d'une exposition consacrée au patrimoine ... [more ▼]

Rédigé dès 2010 pour faire honneur au professeur Franz Bierlaire, cet article a été publié une première fois en 2012 sous une forme légèrement amendée à l'occasion d'une exposition consacrée au patrimoine déposé au Musée Curtius (Liège) par la COmpagnie de Charité pour le Secours des Pauvres et des Prisonniers (Liège). [less ▲]

Detailed reference viewed: 55 (7 ULg)
See detailChefs-d'oeuvre de la Renaissance italienne. La collection de peintures de François Ier
Fagnart, Laure ULg

Scientific conference (2006, March 01)

Detailed reference viewed: 17 (1 ULg)