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See detailChronic tension-type headache
Fumal, Arnaud ULg; Schoenen, Jean ULg

in Decker, B. C. (Ed.) Chronic daily headaches for clinicians (2005)

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See detailChronic tension-type headache: a multifactorial analysis suggesting disturbance of "limbic pathways" to the brain stem
Schoenen, Jean ULg; Bottin, D.; Juprelle, M. et al

in Clifford Rose, F. (Ed.) New Advances in Headache Research (1991)

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See detailChronic tension-type headache: what is new?
Fernandez-de-las-Penas, Cesar; Schoenen, Jean ULg

in Current Opinion in Neurology (2009), 22(3), 254-61

PURPOSE OF REVIEW: This review discusses current data on nosological boundaries related to diagnosis, pathophysiology and therapeutic strategies in chronic tension-type headache (CTTH). RECENT FINDINGS ... [more ▼]

PURPOSE OF REVIEW: This review discusses current data on nosological boundaries related to diagnosis, pathophysiology and therapeutic strategies in chronic tension-type headache (CTTH). RECENT FINDINGS: Diagnostic criteria of CTTH should be adapted to improve its sensitivity against migraine. It seems that mechanical pain sensitivity is a consequence and not a causative factor of CTTH. Recent evidence is modifying previous knowledge about relationships between muscle tissues and CTTH, suggesting a potential role of muscle trigger points in the genesis of pain. An updated pain model suggests that headache perception can be explained by referred pain from trigger points in the craniocervical muscles, mediated through the spinal cord and the trigeminal nucleus caudalis rather than only tenderness of the muscles themselves. Different therapeutic strategies, pharmacological, physical therapy, psychological and acupuncture, are generally used. The therapeutic efficacy of nonsteroidal anti-inflammatory drugs remains incomplete. The tricyclic antidepressants are the most used first-line therapeutic agents for CTTH. Surprisingly, few controlled studies have been performed and not all of them have found an efficacy superior to placebo. Further, there is insufficient evidence to support/refute the efficacy of physical therapy in CTTH. SUMMARY: Although there is an increasing scientific interest in CTTH, future studies incorporating subgroups of patients who will likely to benefit from a specific treatment (clinical prediction rules) should be conducted. [less ▲]

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See detailChronic tolerance to ethanol-induced sedation: Implication for age-related differences in locomotor sensitization
Quoilin, Caroline; Didone, Vincent ULg; Tirelli, Ezio ULg et al

in Alcohol (2013), 47(4), 317-322

The adolescent brain has been suggested to be particularly sensitive to ethanol-induced neuroadaptations, which in turn could increase the risk of youths for alcohol abuse and dependence. Sensitization to ... [more ▼]

The adolescent brain has been suggested to be particularly sensitive to ethanol-induced neuroadaptations, which in turn could increase the risk of youths for alcohol abuse and dependence. Sensitization to the locomotor stimulant effects of ethanol has often been used as an animal model of ethanol-induced neuroadaptations. Previously, we showed that young mice were more sensitive than adults to the locomotor sensitization induced by high ethanol doses. However, this effect could be due to age-related differences in chronic tolerance to the sedative effects of ethanol. The aim of the present study is to assess chronic tolerance to the sedative effects of ethanol in weaning 21-day-old (P21), adolescent 35-day-old (P35) and adult 63-day-old (P63) female Swiss mice. After a daily injection of saline or 4 g/kg ethanol during 6 consecutive days, all P21, P35 and P63 mice were injected with 4 g/kg ethanol and submitted to the loss of righting reflex procedure. Our results confirm that the sensitivity to the acute sedative effects of ethanol gradually increases with age. Although this schedule of ethanol injections induces significant age-related differences in ethanol sensitization, it did not reveal significant differences between P21, P35 and P63 mice in the development of a chronic ethanol tolerance to its sedative effects. The present results show that age-related differences in the development of ethanol sensitization cannot be explained by differences in chronic ethanol tolerance to its sedative effects. More broadly, they do not support the idea that ethanol-induced sensitization is a by-product of chronic ethanol tolerance. [less ▲]

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See detailChronic Toxic Hepatitis in Beef Calves due to Mycotoxins in Mixed Feed
Theron, Léonard ULg; Callebaut, Alfons; Bayrou, Calixte ULg et al

in Zemljic, Borut; Podpecan, Ozbalt; Zmljic-Jokhadar, Spela (Eds.) Proceedings of the XV middle European Buiatric Congress (2015, June 10)

Mycotoxins intoxination is an emerging disorder in Belgium, due to evolution of cultural practices and harvesting weather conditions. These intoxinations are difficult to diagnose for the vet practioners ... [more ▼]

Mycotoxins intoxination is an emerging disorder in Belgium, due to evolution of cultural practices and harvesting weather conditions. These intoxinations are difficult to diagnose for the vet practioners, since unspecific clinical signs, and their impact on ruminant disorder remains controversial. Although legal concentrations have been established for mycotoxins in the EU, farm forages are most of the time not tested (EU 2006/576/EC). In January 2015, a 500 calvings cross-bred Belgian blue cattle herd (BVDV free) referred a second (the first was directly sent to the rendering-plant) unexplained fatal case of jaundice on a 2 months-old calf to the Clinic for Ruminants of the University of Liège for necropsy. In 2013, a case of jaundice due to a Salmonella dublin hepatocholecystitis had previously diagnosed in this farm (Ronzoni et al., 2014), but so far preventions measures were implemented. Necropsy revealed generalized icterus, mild bilirubinuria, splenomegaly, but no precise etiology. On February a second 2 month old calf with jaundice is referred, lethargic, normothermic with a mild diarrhea, Calf shown generalized jaundice, anemia, elevation of leukocytes (neutrophils, eosinophils and monocytes), TGO, bilirubinemia, total biliary acids and Globulins (alpha2). He had also diminished erythrocytes and albuminemia. Copraemia, leptospirosis serology, leademia, hemoculture and pancreatic enzymes were within normal ranges, ruling out classic causes of jaundice in calf. Abdomen ultrasonography revealed a mild hyperechogenicity of the liver but no gall bladder modifications. Symptomatic treatment was based on symptoms, with fluidotherapy and choleretics. A third calf was referred three days after in a worst clinical condition, with also a severely modified liver enzymes, but no anemia. Three days after, this calf died and a necropsy revealed petechiae and hemorrhages in the abomasum, congestive mucosae in the distal bowel, white depot in the kidney medulla, modified urine and splenomegaly. Bile bacteriology and leptospirosis PCR was negative and liver histopathology revealed a severe histopathological liver degeneration associated with a disruption of the parenchyma and marked hyperplasia of the bile ducts compatible with chronic metabolic disorder. Meanwhile, the anemic calf recovered from anemia without any treatment after 4 days and was discharged from the Clinic for Ruminants. Considering the weird clinical patterns of these jaundice cases, and the fact that only calves from 2 to 3 months were affected, a nutritional origin as etiology was suspected. To test it, eight clinically healthy two to three months-old calves, of two different pens were sampled. TGO, GLDH, GGT or biliary acids were either modified and the values tended to increase with the age of the calves. The water was analyzed for classic toxics, and cultured for total germ content and everything were within recommended values. The calves fed with a milk replacer (30 % milk powder), and a commercial calf starter until one month of age. Then, they were given a mixed feed (containing cereal mix, cocoa, beet pulp, soja, maize), made at the farm from primary product/byproducts bought from different sources. The mix was tested for mycotoxins presence and ranged from 0.8 to 1.5 ppm of Desoxynivalenone (DON), and 115-215 ppb of Zearalenone (ZEA). The principal source of DON was maize (3.1 to 6.2 ppm), as for ZEA (0.3-0.6 ppm), but several compounds contained small dose of DON (0.2-0.7 ppm) for Barley feed, Tanned soja. Cacao contained 2.7 to 5.9 ppb of Ochratoxine (OTA). Nutritionnal recommendations were immediately given with a change in the source of maize and an addition of clay and yeast at 40g/calf/day and hay. Since, any other hypothetic origin to this progressive hepatic intoxination was demostrated, and that the doses founded, even if barely legal in the mix, are not accounted for toxic in the EU regulation, we believe that the calves were chronically exposed to these toxins. However, some mycotoxins experts still claim that various clinical signs would be observed in ruminants, if the rumen is partially defaunated, like in our case with the lake of forage. We propose that monitoring of subclinical liver health could be a key to screen DON effects. [less ▲]

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See detailChronic Toxicity Of Essential Oils Of 3 Local Aromatic Plants Towards Sitophilus Zeamais Motsch (Coleoptera : Curculionidae)
Ngamo, Tinkeu L.S.; Goudoum, A.; Ngassoum, Martin B. et al

in African Journal of Agricultural Research (2007), 2(4), 164-167

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See detailChronic varicella-zoster virus skin lesions in patients with human immunodeficiency virus are related to decreased expression of gE and gB
Nikkels, Arjen ULg; Rentier, Bernard ULg; Pierard, Gérald ULg

in Journal of Infectious Diseases (1997), 176(1), 261-264

The pathogenesis of chronic, verrucous varicella-zoster virus (VZV) cutaneous lesions in human immunodeficiency virus (HIV)-infected persons is unknown. It has been hypothesized that these lesions are due ... [more ▼]

The pathogenesis of chronic, verrucous varicella-zoster virus (VZV) cutaneous lesions in human immunodeficiency virus (HIV)-infected persons is unknown. It has been hypothesized that these lesions are due to an altered pattern of virus gene expression. Immediate early and late (L) gene expression in five chronic verrucous VZV lesions, four full-blown herpes zoster vesicular lesions in HIV-infected persons, and eight vesicular herpes zoster lesions in immunocompetent individuals was semiquantitatively assessed immunohistochemically using specific antibodies to the IE63, gE (L), and gB (L) proteins. All patients had evidence of IE63 expression in keratinocytes; however, gE expression was either weak or absent in keratinocytes of three verrucous lesions, and gB was either weak or absent in two. These results suggest that chronic VZV skin lesions are associated with diminished gE and gB expression. It is inferred that the VZV behavior in keratinocytes may vary from a latency-like state to a fully developed, productive infection. [less ▲]

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See detailChronic verrucous varicella zoster virus skin lesions: clinical, histological, molecular and therapeutic aspects
Nikkels, Arjen ULg; Snoeck, Robert; Rentier, Bernard ULg et al

in Clinical & Experimental Dermatology (1999), 24(5), 346-353

The outbreak of HIV infection introduced a new phenomenon in varicella zoster virus (VZV) pathology, namely the long-standing wart-like skin lesions that are frequently associated with resistance to ... [more ▼]

The outbreak of HIV infection introduced a new phenomenon in varicella zoster virus (VZV) pathology, namely the long-standing wart-like skin lesions that are frequently associated with resistance to thymidine kinase (TK)-dependent antiviral agents. This paper reviews the clinical, histological, and molecular aspects and the therapeutic management of these verrucous lesions. The majority of lesions are characterized by chronically evolving, unique or multiple wart-like cutaneous lesions. The main histopathological features include hyperkeratosis, verruciform acanthosis and VZV-induced cytopathic changes with scant or absent cytolysis of infected keratinocytes. The mechanism that establishes the chronic nature of the lesions appears to be associated with a particular pattern of VZV gene expression exhibiting reduced or nondetectable gE and gB synthesis. Drug resistance to TK-dependent antiviral agents is a result of nonfunctional or deficient viral TK. This necessitates alternative therapeutic management using antiviral agents that target the viral DNA polymerase. [less ▲]

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See detailChronic vertebral osteomyelitis in an adult draft horse
Amory, Hélène ULg; Vandenput, Sandrina ULg; Godisiabois, Y et al

in Proceedings of the XXVth Congress of the World Veterinary Association, Yokohama, Japan (1995)

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See detailChronically injured corticospinal axons do not cross large spinal lesion gaps after a multifactorial transplantation strategy using olfactory ensheathing cell/olfactory nerve fibroblast-biomatrix bridges
Deumens, R.; Koopmans, G. C.; Honig, W. M. M. et al

in Journal of Neuroscience Research (2006), 83(5), 811-820

Transplantation of mixed cultures containing olfactory ensheathing cell (OEC) and olfactory nerve fibroblasts (ONF) has been shown to stimulate regrowth of both acutely and chronically injured ... [more ▼]

Transplantation of mixed cultures containing olfactory ensheathing cell (OEC) and olfactory nerve fibroblasts (ONF) has been shown to stimulate regrowth of both acutely and chronically injured corticospinal (CS) axons across small spinal cord lesion gaps. Here, we used a multifactorial transplantation strategy to stimulate regrowth of chronically injured CS axons across large spinal cord lesion gaps. This strategy combined the transplantation of aligned OEC/ONF-biomatrix complexes, as described previously (Deumens et al. [2004] Neuroscience 125:591-604), within the lesion gap with additional OEC/ONF injections rostral and caudal to the lesion site. We show an enhanced presence of injured CS axons directly rostral to the lesion gap, with no effects on injured CS axons at or caudal to the lesion gap. Furthermore, injured CS axons did not penetrate the OEC/ONF-biomatrix complex within the lesion gap. The enhanced presence of CS axons rostral to the lesion gap was not accompanied by any recovery of behavioral parameters assessed with the BBB locomotor rating scale or CatWalk gait analysis. We conclude that our multifactorial transplantation strategy should be optimized to create an OEC/ONF continuum in the injured spinal cord and thereby stimulate regrowth of injured CS axons across large spinal lesion gaps. [less ▲]

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See detailChronicle of a superficial pigmented basal cell carcinoma.
CAUCANAS, Marie ULg; FRANCHIMONT, Claudine ULg; PIERARD, Gérald ULg

in Case Reports in Dermatological Medicine (2012), 2012(693041),

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See detailChronique - Cour de Justice et Tribunal de l'Union européenne - Concurrence
Petit, Nicolas ULg; Lousberg, Charlotte ULg

in Journal du Droit International - Clunet (2012), (2), 747-759

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See detailChronique archéologique de la religion grecque 2011 - Dodécanèse
Paul, Stéphanie ULg; Massar, Natacha; D'Hautcourt, Alexis

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (2011), 24

Detailed reference viewed: 12 (3 ULg)
See detailChronique bibliographique - 2005-2008
Veymiers, Richard ULg; Bricault, Laurent; Budischovsky, Marie-Christine et al

in Bricault, Laurent; Veymiers, Richard (Eds.) Bibliotheca Isiaca II (2011)

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications ... [more ▼]

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications touchant aux cultes isiaques entre 2005 et 2008. [less ▲]

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See detailChronique bibliographique - 2009-2012
Veymiers, Richard ULg; Bricault, Laurent; Malaise, Michel et al

in Bricault, Laurent; Veymiers, Richard (Eds.) Bibliotheca Isiaca III (2014)

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications ... [more ▼]

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications touchant aux cultes isiaques entre 2009 et 2012. [less ▲]

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See detailChronique bibliographique - Supplément 2000-2004
Veymiers, Richard ULg; Bricault, Laurent; Budischovsky, Marie-Christine et al

in Veymiers, Richard; Bricault, Laurent (Eds.) Bibliotheca Isiaca II (2011)

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications ... [more ▼]

Chronique bibliographique qui, sur le modèle de "l’Inventaire Bibliographique des Isiaca" (IBIS), publié dans les "ÉPRO" entre 1972 et 1991, recense, avec un commentaire critique, les publications touchant aux cultes isiaques entre 2000 et 2004. [less ▲]

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See detailChronique bibliographique - Supplément 2005-2008
Veymiers, Richard ULg; Bricault, Laurent; Malaise, Michel et al

in Bricault, Laurent; Veymiers, Richard (Eds.) Bibliotheca Isiaca III (2014)

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See detailChronique d'actualités en droit commercial
Thirion, Nicolas ULg

Book published by Larcier (2013)

Cet ouvrage fait le point sur les principales nouveautés en droit commercial apparues depuis 2010

Detailed reference viewed: 106 (14 ULg)
See detailChronique de compétence
Grella, Vanessa ULg

in BOULARBAH H. et GEORGES F. (Ed.) Actualités en droit judiciaire - CUP (2010)

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See detailChronique de criminologie: Quels supporters pour l'an 2000?
Kellens, Georges ULg; Comeron, Manuel ULg

in Revue de Droit Pénal et de Criminologie (1996), (3), 306-312

Detailed reference viewed: 18 (3 ULg)