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See detailComparison of inhibitory functioning in mild Alzheimer's disease and frontotemporal dementia
Collette, Fabienne ULg; Amieva, Hélène; Adam, Stéphane ULg et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2007), 43(7), 866-874

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and ... [more ▼]

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and inhibitory deficits are also prominent in patients with FTD. However, few studies have simultaneously explored and compared inhibitory abilities in both degenerative diseases. Consequently, the aim of this study was to compare verbal and motor inhibitory processes in the initial stages of AD and the frontal variant of FTD. Stroop and Go/No-go tasks were administered. The results demonstrate that, on the Go/No-go task, AD and FTD patients do not produce more errors than control subjects. However, both groups are impaired on the Stroop task (mainly with regard to the error score) but do not differ from each other. These results indicate that AD and FTD patients do not present a general impairment of their inhibitory abilities. Moreover, these two kinds of dementia present similar quantitative and qualitative inhibitory impairments on the two tasks, although their patterns of structural and functional cerebral impairments are known to be different. The presence of similar inhibitory deficits despite very different patterns of brain damage is in agreement with the hypothesis that inhibitory dysfunction in the two groups of patients depends on a disconnection process between anterior and posterior cerebral areas, rather than on the presence of focal metabolism decreases in different regions. [less ▲]

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See detailComparison of insulin degludec with insulin glargine in insulin-naive subjects with Type 2 diabetes: a 2-year randomized, treat-to-target trial.
Begin once trial investigators; RADERMECKER, Régis ULg

in Diabetic Medicine : A Journal of the British Diabetic Association (2013)

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See detailComparison of insulin degludec with insulin glargine in insulin-naive subjects with Type 2 diabetes: a 2-year randomized, treat-to-target trial.
BEGIN Once Long Trial Investigators; RADERMECKER, Régis ULg

in Diabetic Medicine : A Journal of the British Diabetic Association (2013)

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See detailComparison of intense nightside shock induced aurora and substorms activity
Meurant, M.; Gérard, Jean-Claude ULg; Blockx, Caroline ULg et al

Conference (2004, December 01)

Variations of the solar wind dynamic pressure induce perturbation of magnetospheric processes. These perturbations frequently induce dayside enhancements of activity with particular features such as low ... [more ▼]

Variations of the solar wind dynamic pressure induce perturbation of magnetospheric processes. These perturbations frequently induce dayside enhancements of activity with particular features such as low latitude proton flash, low latitude arcs and aurora propagating eastward and westward from noon to the night sector. In some cases, these shocks may also induce an enhancement of the nightside activity during which the power precipitated in the night sector may reach values as high as observed during substorms. Various studies have shown that high precipitated powers are more likely during period of negative values of the North - South IMF components. Liou et al (2003) have shown that substorm-like activity is not frequent after a shock and they concluded that a shock may not be considered as a substorm trigger. The question addressed in this study is to know up to what point the substorm like nightside activity triggered by a shock is comparable to a classical substorm. For this purpose, we analyze four events presenting nightside activity morphologically similar to substorms and occurring within a short time (less than 20 minutes) after the arrival of a pressure pulse on the front of the magnetosphere. Different features of these events such as the mean energy of precipitated electrons, the motion of boundaries before and after onset and the power precipitated in the nightside region are compared to typical substorms. Except for the absence of southward motion of activity before onset, shock induced substorms appear very similar to isolated substorms. We investigate the ability of a shock to trigger a substorm during periods characterized by particular conditions. We suggest that the sign of B[SUB]z[/SUB] plays an important role as well as the history of solar wind and interplanetary magnetic field and the resulting state of the magnetosphere. [less ▲]

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See detailComparison of intense nightside shock-induced precipitation and substorm activity
Meurant, M.; Gérard, Jean-Claude ULg; Blockx, Caroline ULg et al

in Journal of Geophysical Research. Space Physics (2005), 110(A7),

[1] Sudden variations of the solar wind dynamic pressure frequently induce dayside enhancements of auroral activity with features such as high-latitude arcs, low-latitude proton flashes, and enhancement ... [more ▼]

[1] Sudden variations of the solar wind dynamic pressure frequently induce dayside enhancements of auroral activity with features such as high-latitude arcs, low-latitude proton flashes, and enhancement of auroral precipitation propagating dawnward and duskward from noon to the night sector. In some cases, these shocks also induce enhanced activity during which the power precipitated into the night sector may reach values as high as observed during substorms. Several studies have shown that the triggering of nightside-enhanced precipitation is more likely during periods of southward interplanetary magnetic field (IMF) components. Early works showed that substorm-like activity is not frequent after a shock and suggested that shocks may not be considered as substorm triggers. We examine up to what point substorm-like nightside activity triggered by a shock is comparable to an isolated substorm. For this purpose, we analyze three events morphologically similar to substorms and occurring within less than 20 min after the arrival of a pressure pulse on the front of the magnetosphere. Different features of these events such as the mean energy of precipitated electrons, the latitudinal motion of boundaries before and after onset, and the power precipitated into the nightside sector are compared with isolated substorms. We conclude that the characteristics of shock-induced substorms appear very similar to those of isolated substorms. Shocks are able to trigger substorms when they hit an unstable magnetosphere. The interpretation is that the perturbation due to the shock induces a substorm by closure of the plasma sheet magnetic field. For the events presented in this study, the instability result from a period of southward IMF or stretching of the magnetic tail induced by a previous shock. [less ▲]

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See detailComparison of intracellular and extracellular particles of the vaccinia virus
Vanderplasschen, Alain ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1999), 154

The construction of recombinant vaccinia viruses (VV) is definitely a promising approach to develop vaccines for pets. To produce safer VV recombinant vaccines, it is necessary to understand the ... [more ▼]

The construction of recombinant vaccinia viruses (VV) is definitely a promising approach to develop vaccines for pets. To produce safer VV recombinant vaccines, it is necessary to understand the pathogenesis of VV infection. The goal of this study was to compare the biological properties of the extracellular and intracellular infectious particles of VV. Four biological properties were investigated: (i) the binding into cellular receptor(s); (ii) the mechanism of entry; (iii) the resistance to neutralisation by antibodies; (iv) the resistance to complement lysis. The results obtained in this study emphasize the differences existing between the two infectious forms of VV and demonstrate the adaptation of the extracellular particle to its role of virus dissemination in vivo. The results of this study implicate that VV strains used as expression vector in vaccinology should be deleted for genes required for EEV morphogenesis. [less ▲]

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See detailComparison of inulin to urea as dilutional marker of bronchoalveolar lavage in an animal model of asthma
Kirschvink, Nathalie; Fievez, Laurence ULg; Dogné, S. et al

in Proceedings: International Conference of the American Thoracic Society (2001)

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See detailComparison of inulin with urea as dilutional markers of bronchoalveolar lavage in healthy and heaves-affected horses.
Kirschvink, Nathalie; Fievez, Laurence ULg; Dogne, S. et al

in Veterinary Research (2001), 32(2), 145-154

Solute analysis in bronchoalveolar lavage fluid involves the use of dilutional markers to correct for variable recovery of pulmonary epithelial lining fluid (PELF). Urea is the best characterised ... [more ▼]

Solute analysis in bronchoalveolar lavage fluid involves the use of dilutional markers to correct for variable recovery of pulmonary epithelial lining fluid (PELF). Urea is the best characterised endogenous marker, whereas inulin appears to meet the requirements of an exogenous marker. In horses, the use of inulin has never been investigated and the impact of lower airway diseases such as heaves, on PELF recovery is unknown. In this study, five healthy and five heaves-affected horses underwent airway endoscopy and bronchoalveolar lavage. PELF recovery from bronchoalveolar lavage was calculated by the inulin and the urea method. The inulin method was compared to the urea method and differences between healthy and heaves-affected horses were analysed. From a technical and analytical point of view, inulin fulfilled the requirements of a marker of dilution as well as urea. When both healthy and heaves-affected horses groups were pooled together, PELF recovery calculated by the inulin method was significantly higher than by the urea method (6.43+/-4.08% versus 0.789+/-0.299%, P < 0.005). No significant differences were observed between healthy and heaves-affected horses, neither by the inulin nor by the urea method. Inulin did not present major advantages over urea, but the combined use of both markers can improve the standardisation of studies comparing PELF compounds, by providing upper limits (inulin dilution) and lower limits (urea dilution) of PELF recovery. [less ▲]

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See detailComparison of IUE and HST diagnostic of the Jovian aurorae
Thomas, Alexandre ULg; Prangé; Ballester, G. E. et al

in Bulletin of the American Astronomical Society (1994, June 01)

Not Available

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See detailComparison Of Jupiter's Infrared And Uv Aurorae With Simultaneous And Near-simultaneous HST And Ground-based Observations
Lystrup, Makenzie B; Radioti, Aikaterini ULg; Bonfond, Bertrand ULg et al

Conference (2010, October)

Jupiter's UV aurorae have been observed extensively for the last twenty years using the Hubble Space Telescope and the infrared aurorae have been investigated using ground-based telescope observations ... [more ▼]

Jupiter's UV aurorae have been observed extensively for the last twenty years using the Hubble Space Telescope and the infrared aurorae have been investigated using ground-based telescope observations. The two wavelength regimes complement each other; the UV is a tracer of inputs from the magnetosphere while the infrared emissions from the H3+ molecular ion show how the ionosphere responds to those inputs. Between 1995 and 2000 Spectroscopic, J.E.P Connerney & T. Satoh carried out observations with the NSFCAM imaging instrument at the NASA Infrared Telescope Facility. Results from this data set have been published, although the entire data set has not been examined and there has been only limited comparison with the UV. We reanalyze this data set in order to statistically characterize the infrared aurora and compare with the UV. Here we present a detailed study of simultaneous and near-simultaneous observations of the UV (STIS instrument on HST) and infrared northern aurorae made on July 26, 1998 and December 16, 2000. The comparative study addresses the main oval emissions, satellite footprints, and polar aurorae. M. Lystrup is supported by an NSF Astronomy and Astrophysics Postdoctoral Fellowship under award AST-0802021. [less ▲]

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See detailComparison of Kohonen's Self-Organizing Map algorithm and principal component analysis in the exploratory data analysis of a groundwater quality dataset
Peeters, Luk; Dassargues, Alain ULg

(2006)

Groundwater monitoring networks typically yield large, multivariate datasets. Analysis and interpretation of these datasets starts with an exploratory data analysis in order to summarize the available ... [more ▼]

Groundwater monitoring networks typically yield large, multivariate datasets. Analysis and interpretation of these datasets starts with an exploratory data analysis in order to summarize the available data, extract useful information and formulate hypotheses for further research. Exploratory data analysis is mostly focussed on finding related variables and groupings of similar observations. Traditionally multivariate statistical techniques like principal component analysis (PCA) are used for this purpose. In PCA a linear dimensionality reduction of the original, high dimensional dataset is carried out in order to identify orthogonal directions (principal components) of maximum variance in the dataset based on linear combinations of correlated variables. Projections of the original data in the subspace defined by the principal components can be used to identify groups in the data and to reveal relationships between variables (Davis, 1986). In this study, principal component analysis is compared to Kohonen's self-organizing map (SOM) algorithm. The SOM-algorithm is an artificial neural network technique designed to carry out a non-parametric regression process that is mainly used to represent high-dimensional, nonlinearly related data items in a topology-preserving, often two-dimensional display, and to perform unsupervised classification and clustering (Kohonen, 1995). Both PCA and SOM are applied to a hydrochemical dataset from a monitoring network in two sandy, phreatic aquifers in Central Belgium. The monitoring network consists of 47 monitoring wells each equipped with three filters at different depths, in which 14 variables are measured. The first aquifer, the Diest sands aquifer is of Late Miocene age and consists of coarse, glauconiferous sands and sandstones (Laga et al., 2001). The second aquifer, the Brussels sands aquifer, is of Middle Eocene age and is an heterogeneous formation consisting of an alteration of highly and poorly calcareous sands, locally silicified (Laga et al., 2001). Both techniques succeed in distinguishing between both aquifers and reveal the relationships between variables. The main advantage of PCA is the mathematical quantification of correlation between variables and the expression of the original data in the subspace defined by the principal components. The visualization of the SOM-analysis on the other hand allows a straightforward interpretation of the dataset structure in which even non-linear relationships between variables can be identified. Additionally, the SOM-algorithm can handle a limited amount of missing values in the dataset, contrary to PCA. [less ▲]

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See detailComparison of learning curves and skill transfer between classical and robotic laparoscopy according to the viewing conditions: implications for training
Blavier, Adelaïde ULg; Gaudissart, Quentin; Cadière, Guy-Bernard et al

in American Journal of Surgery (2007), 194(1), 115-121

BACKGROUND: The purpose of this study was to evaluate the perceptual (2-dimensional [2D] vs. 3-dimensional [3D] view) and instrumental (classical vs. robotic) impacts of new robotic system on learning ... [more ▼]

BACKGROUND: The purpose of this study was to evaluate the perceptual (2-dimensional [2D] vs. 3-dimensional [3D] view) and instrumental (classical vs. robotic) impacts of new robotic system on learning curves. METHODS: Forty medical students without any surgical experience were randomized into 4 groups (classical laparoscopy with 3D-direct view or with 2D-indirect view, robotic system in 3D or in 2D) and repeated a laparoscopic task 6 times. After these 6 repetitions, they performed 2 trials with the same technique but in the other viewing condition (perceptive switch). Finally, subjects performed the last 3 trials with the technique they never used (technical switch). Subjects evaluated their performance answering a questionnaire (impressions of mastery, familiarity, satisfaction, self-confidence, and difficulty). RESULTS: Our study showed better performance and improvement in 3D view than in 2D view whatever the instrumental aspect. Participants reported less mastery, familiarity, and self-confidence and more difficulty in classical laparoscopy with 2D-indirect view than in the other conditions. CONCLUSIONS: Robotic surgery improves surgical performance and learning, particularly by 3D view advantage. However, perceptive and technical switches emphasize the need to adapt and pursue training also with traditional technology to prevent risks in conversion procedure. [less ▲]

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See detailComparison of less lethal 40 mm sponge projectile and the 37 mm projectile for injury assessment on human thorax
Nsiampa Ndompetelo, ULg; Robbe, Cyril ULg

in 10th International Conference on the mechanical and physical behaviour of materials under dynamic loading, Freiburg 2-7 September 2012 (2012)

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See detailComparison of levels of cytosol estrogen receptors with "arterial" and "venous" concentrations of gonadic steroids in mammary tumors.
Duvivier, Joseph; Colin, Claude; Hustin, Jean et al

in Clinica Chimica Acta (1981), 112(1), 21-32

Plasma steroid concentrations measured in the post-menopausal women with breast cancer showed a close correlation between the various androgens. The post-menopausal women exhibited a correlation between ... [more ▼]

Plasma steroid concentrations measured in the post-menopausal women with breast cancer showed a close correlation between the various androgens. The post-menopausal women exhibited a correlation between estrogen receptors (ER) and "arterial" 17 alpha-hydroxyprogesterone levels in the breast. ER levels expressed as a function of plasma (arterial) steroid (P/17 P) molar concentration ratio were distributed within a hyperbola, suggesting the existence of a control mechanism for breast cell ER levels. [less ▲]

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See detailComparison of liaison N-tact PTH (diasorin) and N-tact PTH SPIRMA (diasorin) in hemodialyzed patients
Cavalier, Etienne ULg; Delanaye, Pierre ULg; Krzesinski, Jean-Marie ULg et al

in Clinical Chemistry & Laboratory Medicine (2005), 43(8), 890-891

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See detailComparison of linkage and association strategies for quantitative traits using the COGA dataset
McQueen, M. B.; Murphy, A.; Kraft, P. et al

in Genetic Epidemiology. Supplement (2005), 29(Suppl I), 1-9

Genome scans using dense single-nucleotide polymorphism ( SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser ... [more ▼]

Genome scans using dense single-nucleotide polymorphism ( SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser scans will help refine previously identified linkage regions and possibly identify new regions not identifiable using the sparser, microsatellite scans. In the context of the dense SNP scans, it is also possible to consider association strategies to provide even more information about potential regions of interest. To circumvent the multiple-testing issues inherent in association analysis, we use a recently developed strategy, implemented in PBAT, which screens the data to identify the optimal SNPs for testing, without biasing the nominal significance level. We compare the results from the PBAT analysis to that of quantitative linkage analysis on chromosome 4 using the Collaborative Study on the Genetics of Alcoholism data, as released through Genetic Analysis Workshop 14. [less ▲]

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See detailComparison of linkage and association strategies for quantitative traits using the COGA dataset.
McQueen, M. B.; Murphy, A.; Kraft, P. et al

in BMC Genetics (2005), 6 Suppl 1

ABSTRACT : Genome scans using dense single-nucleotide polymorphism (SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the ... [more ▼]

ABSTRACT : Genome scans using dense single-nucleotide polymorphism (SNP) data have recently become a reality. It is thought that the increase in information content for linkage analysis as a result of the denser scans will help refine previously identified linkage regions and possibly identify new regions not identifiable using the sparser, microsatellite scans. In the context of the dense SNP scans, it is also possible to consider association strategies to provide even more information about potential regions of interest. To circumvent the multiple-testing issues inherent in association analysis, we use a recently developed strategy, implemented in PBAT, which screens the data to identify the optimal SNPs for testing, without biasing the nominal significance level. We compare the results from the PBAT analysis to that of quantitative linkage analysis on chromosome 4 using the Collaborative Study on the Genetics of Alcoholism data, as released through Genetic Analysis Workshop 14. [less ▲]

Detailed reference viewed: 16 (6 ULg)