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See detailLa césarienne chez la vache : entre théorie et pratique
Hanzen, Christian ULg

in Proceedings des journées nationales vétérinaires (2012, May 23)

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See detailLa césarienne dans l'espèce bovine
Hanzen, Christian ULg; Lourtie, O; Ectors, Francis

in Annales de Médecine Vétérinaire (1999), 143

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See detailLa césarienne dans l'espèce bovine. Protocole de réalisation.
Hanzen, Christian ULg

Conference (2004, March)

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See detailLa césarienne dans l’espèce bovine. Résultats d’une enquête internationale relative aux indications, modalités techniques et thérapeutiques de réalisation et conséquences.
Hanzen, Christian ULg; Gauthier, Bernard; Paindavenne, Pierre et al

in Comptes-rendus des journées nationales des groupements techniques vétérinaires (2010, May 27)

Le texte présente les résultats d’une enquête sur les indications les circonstances et techniques opératoires de la césarienne chez la vache.508 vétérinaires de différents pays ont répondu au ... [more ▼]

Le texte présente les résultats d’une enquête sur les indications les circonstances et techniques opératoires de la césarienne chez la vache.508 vétérinaires de différents pays ont répondu au questionnaire proposé (www.upv/cesarienne/. Dans la majorité des cas, la césarienne est pratiquée en race charolaise(32.3%) ou Blanc Bleu Belge (29.9%) pour cause de disproportion foeto pelvienne(64.6% des cas) sans tranquilisation générale( (80%) , sous anesthésie locale ou loco régionale ,en position debout sur le flanc gauche (98.5%). La désinfection se fait dans 74.5% des cas à la chlorhexidine, 99% des confrères ont recours à un traitement anti microbien post opératoire, 85 % n’utilisent pas de traitement anti inflammatoire après l’intervention. Les vétérinaires estiment à 5.6% la fréquence moyenne des complications dans les trois premières semaines suivant la césarienne .A ce stade il s’agit d’une enquête purement descriptive appelée à être complétée. Un appel est lancé aux praticiens pour réfléchir aux avantages et inconvénients des différentes pratiques . La publication d’un cahier des charges de nature à aider les confrères est envisagé . [less ▲]

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See detailCésarienne urgente: quel délai, quelle organisation?
Brichant, Jean-François ULg

Conference (2006, June 10)

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See detailCésarienne urgente: quel délai, quelle organisation?
Brichant, Jean-François ULg

in 24e Journées Internationales de Mises Au Point en Anesthésie-Réanimation. Communications scientifiques MAPAR 2006 (2006)

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See detailCesàrolite, a possible member of the birnessite group of minerals
Perchiazzi, Natale; Hatert, Frédéric ULg; Merlino, Stefano et al

Poster (2008)

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See detailCessation of intensive treatment with recombinant human erythropoietin is followed by secondary anemia.
Piron, Maude ULg; Loo, Martine; Gothot, André ULg et al

in Blood (2001), 97(2), 442-8

Little information is available on the evolution of erythropoiesis after interruption of recombinant human erythropoietin (rHuEpo) therapy. Iron-overloaded rats received 20 daily injections of rHuEpo ... [more ▼]

Little information is available on the evolution of erythropoiesis after interruption of recombinant human erythropoietin (rHuEpo) therapy. Iron-overloaded rats received 20 daily injections of rHuEpo. During treatment, reticulocytes, soluble transferrin receptor (sTfR), and hematocrit increased progressively. This was accompanied by a substantial expansion of spleen erythropoiesis but a decrease in the bone marrow. Five weeks after treatment, rats developed a significant degree of a regenerative anemia. Erythropoietic activity, as assessed by reticulocytes, sTfR, erythroid cellularity, iron incorporation into heme, and the number of erythroid colonies, was severely depressed 3 weeks after cessation of rHuEpo. This was followed by regeneration of erythroblasts and reticulocytes at weeks 6 to 7 post-Epo, but erythroid progenitors recovered only partially by that time. The anemia was definitely corrected 2 months after cessation of rHuEpo treatment. Serum Epo levels remained elevated for several weeks, but the sensitivity of marrow erythroid precursors to Epo was preserved. No rat antibodies to rHuEpo were detected, and serum from post-Epo animals did not exert any inhibitory activity on erythropoiesis. In conclusion, after cessation of intensive rHuEpo therapy, there was a strong inhibition of erythropoietic activity with secondary anemia followed by late recovery. This was not due to antibodies or other soluble inhibitory factors, a defect in endogenous Epo production, or a loss of sensitivity to Epo. This may rather represent intrinsic erythroid marrow exhaustion, mostly at the level of erythroid progenitors but also at later stages of erythropoiesis. [less ▲]

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See detailCessation versus continuation of 6-month migraine preventive therapy with topiramate (PROMPT): a randomised, double-blind, placebo-controlled trial
Diener, Hans-Christoph; Agosti, Reto; Allais, Gianni et al

in Lancet Neurology (2007), 6(12), 1054-1062

Background Use of preventive therapy for migraine is often recommended for only 6-9 months, but no randomised, placebo-controlled trials have investigated migraine frequency after the end of prophylaxis ... [more ▼]

Background Use of preventive therapy for migraine is often recommended for only 6-9 months, but no randomised, placebo-controlled trials have investigated migraine frequency after the end of prophylaxis. We assessed the effects of discontinuation of topiramate after a treatment period of 6 months. Methods 818 patients who have migraines were enrolled from 88 clinics in 21 countries. After a 4-8-week lead-in period, patients received topiramate in a 26-week open-label phase. Daily dose was increased from 25 mg to 100 mg in steps of 25 mg every week; the dose could be adjusted further in the range 50-200 mg/day, but was stable for the final 4 weeks. Patients were randomly assigned to continue this dose or switch to placebo for a 26-week double-blind phase. The primary endpoint was the difference in number of days with migraine during the last 4 weeks of the double-blind phase compared with the last 4 weeks of the open-label phase. Analysis was by intention to treat. This trial is registered with EudraCT, number 2005-000321-29. Findings 559 patients (68.3%) completed the open-label phase; 514 entered the double-blind phase and were assigned to topiramate (n=255) or placebo (n=259). The mean increase in number of migraine days was greater in the placebo group (1.19 days in 4 weeks, 95% CI 0.71 to 1.66; p < 0.0001) than in the topiramate group (0.10, -0.36 to 0.56; p=0.5756; mean difference between groups -1.09, -1.75 to -0.43). Patients in the placebo group had a greater number of days on acute medication than did those in the topiramate group (mean difference between groups -0.95, -1.49 to -0.41; p=0.0007). Quality of life, as assessed by the MIDAS questionnaire, fell in the placebo group but remained stable in the topiramate group. Patients were more satisfied with the efficacy of topiramate than with that of placebo, whereas satisfaction with tolerability was similar in both treatment groups. Interpretation Sustained benefit was reported after discontinuation of topiramate, although number of migraine days did increase. These findings suggest that patients should be treated for 6 months, with the option to continue to 12 months in some patients. [less ▲]

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See detailLa cession du fonds de commerce
Thirion, Nicolas ULg

Book published by Larcier (2005)

Ouvrage collectif visant à élucider les principales questions juridiques liées à la cession d'un fonds de commerce (à la fois du point de vue du droit civil, du droit commercial, du droit social et du ... [more ▼]

Ouvrage collectif visant à élucider les principales questions juridiques liées à la cession d'un fonds de commerce (à la fois du point de vue du droit civil, du droit commercial, du droit social et du droit fiscal) [less ▲]

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See detailCestodes and Acanthocephalans parasitizing small mammals from Benin
Houemenou, Gualbert; Martin-Alonso, A.; Sanchez, S. et al

Conference (2012, September)

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See detail« Cet obscur objet du désir ». La nudité féminine entre Orient et Grèce
Pirenne-Delforge, Vinciane ULg; Bonnet, Corinne

in Mélanges de l'École Française de Rome. Antiquité (2004), 116

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See detailCette île est mienne... et tu me l'as prise: Shakespeare au XXe siècle
Maes-Jelinek, Hena ULg

in Bulletin de la Classe des Lettres et des Sciences Morales et Politiques (2004), 15(1-6), 23-41

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See detailCette télévision qui cache en montrant
Jamin, Jérôme ULg

Article for general public (2001)

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See detailCFD application : Green Building Design
Reiter, Sigrid ULg

Scientific conference (2012, January 17)

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See detailCFD Comparison of hydrodynamics between BIOSTAT® Cultibag STR and standard Stirred Cell Culture Bioreactors
Calvo, Sébastien ULg; Delafosse, Angélique ULg; Crine, Michel ULg et al

Poster (2014, September 10)

Single-use bioreactors have been increasingly used for animal cell cultures on microcarriers in screening experiments. Because of their manufacturing process, the shape of these kinds of vessels such as ... [more ▼]

Single-use bioreactors have been increasingly used for animal cell cultures on microcarriers in screening experiments. Because of their manufacturing process, the shape of these kinds of vessels such as the BIOSTAT® Cultibag STR one, is limited. For example, technical constraints on weld seams limit angles to 30° and no baffle may be installed. The shape of standard re-usable vessels may thus not be exactly reproduced and the flow structure may thus significantly differs from the flow structure in standard bioreactors. [less ▲]

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See detailCFD Large Eddy Simulation of the hydrodynamics of stirred mini-bioreactors operating with stem cell culture mixing conditions
Collignon, Marie-Laure ULg; Martin, Céline; Toye, Dominique ULg et al

Poster (2015, January 18)

The expansion of hMSC adhered on microcarriers is a proven technology to allow the production of quantitatively (cell density and growth rate) and qualitatively (preservation of cell stemness) the amounts ... [more ▼]

The expansion of hMSC adhered on microcarriers is a proven technology to allow the production of quantitatively (cell density and growth rate) and qualitatively (preservation of cell stemness) the amounts of cells required for clinical applications. In that context of process optimization, a platform of 6 parallel 250 mL stirred minibioreactors have been designed and fully equipped for hMSC cultivation on microcarriers. The local hydrodynamics in these bioreactors have been characterized using CFD simulations and experimental measurements. GOALS: 1) Evaluation of the flexibility of the platform for extensively studying the coupling between hydrodynamics and hMSC physiological response (growth, stemness) by changing agitation conditions. 2) Evaluation of the scale down ability of platform as prediction tool of the hMSC behavior in larger bioreactor scale. [less ▲]

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See detailCFD Modelisation of homogeneous distribution of solid particles in a stirred tank
Calvo, Sébastien ULg; Delafosse, Angélique ULg; Collignon, Marie-Laure ULg et al

Poster (2013, April 24)

In this work, we study the conditions needed to reach homogeneous distribution of solid particles of aluminium salts in water inside a torospherical bottom shaped stirred tank reactor of 70L equipped with ... [more ▼]

In this work, we study the conditions needed to reach homogeneous distribution of solid particles of aluminium salts in water inside a torospherical bottom shaped stirred tank reactor of 70L equipped with a Pfaudler RCI type impeller and three equi-spaced vertical baffles. The aim of the present study is to develop a CFD model describing the quality of particle distribution in industrial scale tanks. This model, validated with experimental data, is afterward used to developed scale-up and scale-down correlations to predict the minimum impeller speed needed to reach homogeneous solid distribution Nhs. The commercial CFD software Fluent 14 is used to model the fluid flow and the solid particle distribution in the tank. The 3D geometry of the tank and the associated mesh are respectively realized by Ansys 14 DesignModeler and Meshing. The Sliding-Mesh approach is used to take the impeller motion into account. Assuming that the discrete solid phase has no influence on the continuous liquid phase behaviour, the fluid flow dynamics may be simulated independently using the well-known k-ε turbulence model. The behaviour of the liquid-solid mixture is then described by implementing the Eulerian Mixture model. Liquid velocity fields simulated by CFD have been validated by comparison with PIV (Particle Image Velocimetry) measurements. Computed values of Nhs are compared with good agreement to experimental data obtained with a nephelometric probe. Results obtained at different scales allowed correlating the Nhs value to the volumetric power consumption. [less ▲]

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See detailCFD-based Compartment model for description of mixing in bioreactors
Delafosse, Angélique ULg; Calvo, Sébastien ULg; Collignon, Marie-Laure ULg et al

in Chemical Engineering Science (2014), 106

In most bioprocesses, it is fundamental to accurately predict the hydrodynamics behavior of bioreactors of different size and its interaction with the biological reaction. Computational Fluid Dynamics can ... [more ▼]

In most bioprocesses, it is fundamental to accurately predict the hydrodynamics behavior of bioreactors of different size and its interaction with the biological reaction. Computational Fluid Dynamics can provide detailed modeling about hydrodynamics and mixing. However, it is computationally intensive, especially when reactions are taken into account. Another way to predict hydrodynamics is the use of “Compartment” or “Network-of-zones” model which are much less demanding in computation time than CFD. However, compartments and fluxes between them are often defined by considering global quantities not representative of the flow complexity. To overcome the limitations of these two methods, a solution is to combine compartment modeling and CFD simulations. The aim of this study is to propose a compartment model where the flow rates between two adjacent compartments are easily computed from the velocity fields obtained by CFD. The mixing evolution predicted by the CFD-based compartment model have been then compared with mixing experiment results. Unlike a CFD mixing simulation and a classical compartment model, the CFD-based compartment model proposed in this work reproduces with a good accuracy the spatial distribution of concentrations during the mixing process and this, without any adjustable parameters. [less ▲]

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