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Peer Reviewed
See detailThe case sensitivity function approach to diagnostic and robust computation: a relaxation strategy
Critchley, Frank; Schyns, Michael ULiege; Haesbroeck, Gentiane ULiege et al

in Antoch, Jaromir (Ed.) COMPSTAT 2004: Proceedings in Computational Statistics (2004)

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See detailA case series: Evaluation of the metabolic safety of aripiprazole
De Hert, M.; Hanssens, L.; van Winkel, R. et al

in Schizophrenia Bulletin (2007), 33(3), 823-830

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic ... [more ▼]

Metabolic abnormalities occur frequently in patients treated with antipsychotics and are of growing concern to clinicians. This study sought to determine whether antipsychotic-associated metabolic abnormalities identified through intensive monitoring can be reversed by switching to aripiprazole. Recent evidence suggests that aripiprazole may exhibit a favorable metabolic safety profile. The study population is a subset of a large (n > 500) ongoing prospective cohort. Thirty-one consecutive patients with schizophrenia who were started on aripiprazole were included in the study. All patients underwent an extensive metabolic evaluation, including an oral glucose tolerance test, at baseline, at 6 weeks, and at 3 months post switch. Metabolic abnormalities were defined as any of the following: new onset diabetes, impaired fasting glucose, impaired glucose tolerance, metabolic syndrome (MetS) according to various definitions, and dyslipidemia. After 3 months of treatment with aripiprazole (mean daily dose 16.3 mg), there was a significant decrease in body weight, body mass index, and waist circumference. There was a significant reduction in fasting glucose, fasting insulin, insulin resistance index, and serum lipids levels (cholesterol, triglycerides, low-density lipoprotein (LDL), LDL/HDL, Chol/HDL, and non-HDL cholesterol). There was also a significant reduction in prolactin levels. All 7 cases of recent onset diabetes were reversed at 3 months follow-up. The MetS was reversed in 50% of patients at 3 months follow-up. Our results support the reversibility of recent onset diabetes on antipsychotic medication when detected early and followed by a switch to aripiprazole. [less ▲]

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See detailCase studies in measurement of random incidence scattering coefficients
Vorländer, Michael; Embrechts, Jean-Jacques ULiege; De Geetere, Lieven et al

in Acta Acustica United With Acustica (2004), 90(5, SEP-OCT), 858-867

In this work measurements of random-incidence scattering coefficients in three laboratories are compared. The sample geometry is sinusoidal. These surfaces are geometrically identical, but they were ... [more ▼]

In this work measurements of random-incidence scattering coefficients in three laboratories are compared. The sample geometry is sinusoidal. These surfaces are geometrically identical, but they were constructed in different scales. So far, measurements of this kind were performed only in scale models. Using turntables in real sample size was hardly considered possible. One result of general importance is that measurements are indeed possible in real-scale reverberation rooms with turntables of 3 m diameter. There are only small differences between the real-scale and model-scale results. Some variations of the standard procedure were tested and the uncertainties identified: mounting of the sample, connection or sealing between sample and base plate, way of rotating the sample, air absorption and time variances. The results presented can be regarded as guidelines for application of ISO/DIS 17497-1. [less ▲]

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See detailCase studies of incorporation of prior information in electrical resistivity tomography: comparison of different approaches
Caterina, David ULiege; Hermans, Thomas ULiege; Nguyen, Frédéric ULiege

in Near Surface Geophysics (2014), 12(4), 451-465

Many geophysical inverse problems are ill-posed and their solution non-unique. It is thus important to reduce the amount of mathematical solutions to more geologically plausible models by regularizing the ... [more ▼]

Many geophysical inverse problems are ill-posed and their solution non-unique. It is thus important to reduce the amount of mathematical solutions to more geologically plausible models by regularizing the inverse problem and incorporating all available prior information in the inversion process. We compare three different ways to incorporate prior information for electrical resistivity tomography (ERT): using a simple reference model or adding structural constraints to Occam's inversion and using geostatistical constraints. We made the comparison on four real cases representing different field applications in terms of scales of investigation and level of heterogeneities. In those cases, when electromagnetic logging data are available in boreholes to control the solution, it appears that incorporating prior information clearly improves the correspondence with logging data compared to the standard smoothness constrain. However, the way to incorporate it may have a major impact on the solution. A reference model can often be used to constrain the inversion; however, it can lead to misinterpretation if its weight is too strong or the resistivity values inappropriate. When the computation of the vertical and/or horizontal correlation length is possible, the geostatistical inversion gives reliable results everywhere in the section. However, adding geostatistical constraints can be difficult when there is not enough data to compute correlation lengths. When a known limit between two layers exists, the use of structural constrain seems to be more indicated particularly when the limit is located in zones of low sensitivity for ERT. This work should help interpreters to include their prior information directly into the inversion process through an appropriate way. [less ▲]

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See detailCase Studies: The Cathedral of Saint-Pierre in Beauvais
Taupin, Jean-Louis; Hoffsummer, Patrick ULiege

in Hoffsummer, Patrick (Ed.) Roof Frames from the 11th to the 19th Century: Typology and Development in Northern France and in Belgium: Analysis of CRMH Documentation (2009)

Detailed reference viewed: 54 (1 ULiège)
See detailCase Studies: The Tie Rods and Timber Roof of Notre-Dame Cathedral in Amiens
Hoffsummer, Patrick ULiege; Lambert, Georges-Noël

in Hoffsummer, Patrick (Ed.) Roof Frames from the 11th to the 19th Century: Typology and Development in Northern France and in Belgium: Analysis of CRMH Documentation (2009)

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See detailCase Study "Compensation and Livelihood Restoration at Nam Theun 2 Hydropower Project"
Kouangpalath, Phimthong ULiege; Sacklokham, Silinthone; Kousonsavath, Chitpasong

Report (2014)

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See detailCase study 2: Groundwater – surface water interaction in limestone areas of the GWB BE_Meuse_RWM021 (Belgium)
Brouyère, Serge ULiege; Briers, Pierre ULiege; Schmit, Flore et al

in Hinsby, Klaus; Schutten, Johan; Craig, Matt (Eds.) et al Technical Report on Groundwater Associated Aquatic Ecosystems (2015)

The achievement of good status in groundwater bodies involves meeting a series of conditions, which are defined in the Water Framework Directive (WFD) and, in the case of good chemical status, are given ... [more ▼]

The achievement of good status in groundwater bodies involves meeting a series of conditions, which are defined in the Water Framework Directive (WFD) and, in the case of good chemical status, are given further detail in the Groundwater Directive (GWD). One of these conditions is to ensure that groundwater inputs to associated surface waters do not result in failure to meet the environmental objectives of those waters or result in significant diminution in status/ecological or chemical quality of those waters. GWAAE (Groundwater Associated Aquatic Ecosystems) are those surface water bodies (SWBs), including rivers, standing waters and transitional waters where the surface water ecology and hydrology is dependent on contributions from groundwater in order to meet their environmental objectives under the WFD. These environmental objectives may vary, and therefore the associated environmental quality standards (EQS) or flow/level requirements of GWAAEs may differ between high status and good status SWBs. As noted in the Blueprint for Water, analysis of the first River Basin Management Plans has shown that Member States (MS) have experienced difficulties in understanding the interactions between groundwater and surface water and undertaking the necessary status assessments. This was highlighted in a survey carried out by Working Group Groundwater (WGGW) in 2014/15, which indicated that only half of the MS had assessed quantitative interactions and very few had addressed chemical pressures, including the derivation of threshold values (TVs) that were appropriate to the WFD objectives for GWAAEs. This report aims to further knowledge on what GWAAE are, how they are aligned to WFD processes, and support Member States to properly include the needs of these ecosystems in river basin management planning. The report clarifies the categories of GWAAE and their relative dependence on groundwater and collates current available knowledge and experience via a number of examples and case studies. Terminology and status assessment procedures are explained and pragmatic approaches are proposed which leave some flexibility for MS to adapt to their own specific needs. This technical report, which is not a "guidance document", makes use of and complements existing CIS documents, including existing technical reports on groundwater dependent terrestrial ecosystems (GWDTEs) and Guidance Document 18 (Guidance on Groundwater Status and Trend Assessment). A number of recommendations for technical users of the report are highlighted in boxes in each Chapter. The common themes from these recommendations are collated in Chapter 8, as issues and questions to WGGW and MS in general. The key message from this is the need for closer interaction between scientific disciplines, practitioners and Working Groups in developing conceptual understanding for GWAAEs and implementation of WFD requirements, including identification of GWAAEs, their characterisation and monitoring, and adopting appropriate status assessment methodologies. [less ▲]

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See detailCase study at Attapeu: chicken model
Andres, Ludovic ULiege

Learning material (2015)

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See detailCase study concerning the opportunity of installing cogeneration system in an existing industrial site
Dumont, Marie-Noëlle ULiege

in Proceedings ECCE-1, Volume 3 (1997, May 04)

The combined production of heat and power using cogeneration systems is one of the investigated area to reduce the global CO2 production of the industrial activities in Europe. Due to the time scale of ... [more ▼]

The combined production of heat and power using cogeneration systems is one of the investigated area to reduce the global CO2 production of the industrial activities in Europe. Due to the time scale of the investment, the appropriate sizing of a cogeneration unit is critical for defining the financial feasibility of the project. The possible efforts that could be made during this time scale for improving the enorgy efficiency of the process can make the cogeneration system oversized or even useless. In this paper, we present two methods that we applied to compute the appropriate size of a cogeneration system to be integrated to an industrial site. The first is directly based ôn the present steam consumption figures. This approach is easier and simpler but the solution is not sure for the future, it leads to a 5.6 MW gas turbine but without reducing the overall energy requirements of the plant. The second is based on energy integration including the optimal use of the steam network for CHP. This approach has the advantage to provide a reliable solution for the future. Using this approach, we have computed an energy savings potential of 60Vo, the energy requirements being satisfied by a 4.6 MW gas turbine, and the possibility of producing a complementary 3 MW with steam turbines. [less ▲]

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See detailA Case Study for a Zero Impact Building in Belgium: Mondo Solar-2002
Attia, Shady ULiege

in International Journal of Sustainable Building Technology and Urban Development (2012), 2(2), 137-142

This paper presents the Solar-2002 zero impact renovation project in Belgium. Its characteristics are based on fundamental principles taking advantage of natural resources by diverting the sun shine and ... [more ▼]

This paper presents the Solar-2002 zero impact renovation project in Belgium. Its characteristics are based on fundamental principles taking advantage of natural resources by diverting the sun shine and rain in the building design. The building has been renovated aiming to achieve principals of occupant health and comfort, energy efficiency, renewable energy production, resource conservation and reduction of environmental impacts. The paper reviews the design concepts including the passive and active strategies and compare building actual performance to actual monitoring results. Innovations related to architectural design, building system performance and simulation are presented. Results show that the house achieved energy and carbon neutral balance, closed water cycle and almost a cradle to cradle building material cycle. However, monitoring results shows the difficulty to maintain optimal thermal comfort during extreme summer and winter periods. Achieving the environmental zero impact objectives is not economically feasible without the subsidies from the federal and regional government. [less ▲]

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See detailA case study of anthropogenic impact on the CO2 levels in low-volume profile of the Balcarka Cave (Moravian Karst, Czech Republic)
Lang, Marek; Faimon, Jiri; Ek, Camille ULiege

in Acta Carsologica (2015), 44(1), 71-80

Anthropogenic impact on CO2 levels was studied in the low-volume chamber connected with the low-profile corridor in Balcarka Cave, the show cave in Moravian Karst, during the period of limited ventilation ... [more ▼]

Anthropogenic impact on CO2 levels was studied in the low-volume chamber connected with the low-profile corridor in Balcarka Cave, the show cave in Moravian Karst, during the period of limited ventilation. Modeling showed that the natural CO2 levels were controlled by the CO2 fluxes (up to ~ 3.14 × 10-2 mol s-1) from adjacent spaces. These fluxes changed with cave airflows and ventilation modes. Two main components of anthropogenic impact were recognized: (1) visitor breathing and (2) visitor movement. The CO2 input derived from individual visitor groups varied from 1.96 × 10-4 to 2.45 × 10-3 mol s-1, which was the significant part of the CO2 fluxes from adjacent spaces. The visitor movement induced the airflows up to 0.2 m3 s-1. They exceeded the natural airflows (up to 3.2 × 10-3 m3 s-1) by factor of more than 60. These airflows caused cave ventilation mode’s switching and, significant drop of CO2 fluxes/levels due to changed ventilation. The study therefore indicates that various anthropogenic influences in show cave can balance and neutralize each other, in dependence on cave morphology and seasonal conditions. [less ▲]

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See detailCase study of contamination by Listeria monocytogenes in raw goat milk cheese: development of a quantitative risk assessment model of the production chain
Korsak Koulagenko, Nicolas ULiege; Delhalle, Laurent ULiege; Daube, Georges ULiege

Conference (2011, August 03)

Introduction: Quantitative Risk assessment could be applied in industries as a tool to control and manage the safety of food products. Purpose: A contamination by Listeria monocytogenes of cheeses made ... [more ▼]

Introduction: Quantitative Risk assessment could be applied in industries as a tool to control and manage the safety of food products. Purpose: A contamination by Listeria monocytogenes of cheeses made from raw milk was reported by the Belgian food agency. This contamination was caused by the presence of an asymptomatic “shedder” goat in the herd. With field and laboratory collected data, a quantitative risk assessment model of the production chain was developed. Methods: A modular risk model was built to simulate the food production pathway covering the milking of goats until the final product for the customers. A dynamic square root model was used to predict the growth rate in relation with the temperature, the pH and the water activity along the production chain with predictive microbiology modules. Results: The shedder goat was identified from the herd and milk samples were taken from the two different parts of the mammary gland with 2.6 log cfu (colonies forming units) Listeria monocytogenes/ml for the right part and absence in 25 ml for the left part of the mammary gland. Numbering of Listeria monocytogenes was carried out on the final products with 3.6 log cfu/g in the fresh not ripened cheeses. The modular risk assessment shows a significant growth of Listeria monocytogenes during chilling and storage of the milk collected the day before the cheese production (increase of 0.6 log cfu/ml) and during adjunction of ferment and rennet to milk (increase of 0.8 log cfu/ml). The model confirms the results obtained in the final products. Significance: The modular risk model gives valuable informations to identify and to control critical steps in the food production chain of goat cheese made from raw milk. Only one shedder goat can cause a high risk to become ill for the consumers of contaminated products. [less ▲]

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Peer Reviewed
See detailA case study of flexible reconnection over expansion joints in a buildings
Plumier, André ULiege; Warnotte, V.; Van Alboom, W.

in Proceedings of the 9th World Seminar on Seismic Isolation, Energy Dissipation and Active Vibration Control of Structures (2005)

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See detailCase study of mixed-use high-rise location at the Greater Paris scale
Saint-Pierre, Claire; Becue, Vincent; Diab, Youssef et al

in Brebbia, C. A.; Hernandez, S.; Tiezzi, E. (Eds.) The Sustainable City VI (2010)

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See detailCase study: Control systems for capacitive inertial sensors
Kraft, Michael ULiege

in Gaura, Elena; Newman, Robert (Eds.) Smart MEMS and Sensor Systems (2006)

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See detailCasein kinase 2 inhibition modulates the DNA damage response but fails to radiosensitize malignant glioma cells.
KROONEN, Jérôme ULiege; Artesi, Maria ULiege; CAPRARO, Valérie ULiege et al

in International Journal of Oncology (2012), 41(2), 776-82

Inhibitors of casein kinase 2 (CK2), a regulator of cell proliferation and mediator of the DNA damage response, are being evaluated in clinical trials for the treatment of cancers. Apigenin was capable of ... [more ▼]

Inhibitors of casein kinase 2 (CK2), a regulator of cell proliferation and mediator of the DNA damage response, are being evaluated in clinical trials for the treatment of cancers. Apigenin was capable of inhibiting the activation of CK2 following gamma irradiation in LN18 and U87 malignant glioma cells. Apigenin and siRNA-mediated CK2 protein depletion further inhibited NF-kappaB activation and altered the Tyr68 phosphorylation of Chk2 kinase, a DNA damage response checkpoint kinase, following irradiation. However, CK2 inhibition did not decrease the ability of these glioma cells to repair double-strand DNA breaks, as assessed by COMET assays and gamma-H2Ax staining. Likewise, apigenin and siRNA-induced depletion of CK2 failed to sensitize glioma cells to the cytotoxic effect of 2 to 10 G-rays of gamma irradiation, as assessed by clonogenic assays. These results contrast with those found in other cancer types, and urge to prudence regarding the inclusion of malignant glioma patients in clinical trials that assess the radiosensitizing role of CK2 inhibitors in solid cancers. [less ▲]

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See detailLa Caserne Cavalier Fonck
Folville, Xavier ULiege

in Duchesne, Jean-Patrick; Henrion, Pierre (Eds.) Patrimoine et réaffectation en Wallonie (2005)

Ancien couvent des Écoliers (14e s.) transformé en caserne de cavalerie (19e s.), le site a été réaménagé en 2.000 pour les écoles supérieures Saint-Luc (architecte E. Moureau, groupe AUSE). Le grand ... [more ▼]

Ancien couvent des Écoliers (14e s.) transformé en caserne de cavalerie (19e s.), le site a été réaménagé en 2.000 pour les écoles supérieures Saint-Luc (architecte E. Moureau, groupe AUSE). Le grand manège est reconverti en théâtre par la Communauté française (architecte. D. Dethier) [less ▲]

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See detailCases en cut-up: une lecture grammatextuelle de Last Look de Charles Burns
Crucifix, Benoît ULiege

Conference (2017, October 18)

Detailed reference viewed: 16 (2 ULiège)