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See detailComparison of the Heart-type fatty acid-binding protein (H-FABP) with the high sensitive cardiac troponin T in healthy runners
LE GOFF, Caroline ULg; Kaux, Jean-François ULg; BREVERS, Eric ULg et al

in Biochimica Clinica (2013, May), 37(SS), 544

Background: Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight protein involved in the intracellular uptake and buffering of long chain fatty in the myocardium. It is an early marker ... [more ▼]

Background: Heart-type fatty acid-binding protein (H-FABP) is a low molecular weight protein involved in the intracellular uptake and buffering of long chain fatty in the myocardium. It is an early marker for acute coronary syndrome. Troponin T (TnT) is a component of the contractile apparatus of the striated musculature. Cardiac TnT is a cardio-specific, highly sensitive marker for myocardial damage. The aim of our study was to compare the results obtained with the H-FABP and the highly sensitive cardiac troponins (hsTnT) and to test their cardiospecificity in healthy runners. Methods: Twenty three runners (marathon) were enrolled. We drowned samples at three times: just before (T0), just after (T1), and three hours after the end of the race (T3). H-FABP was determined with a Randox immunoturbidimetric assay and hs-TnT with a Roche electrochemiluminescence immunoassay, both on Cobas 6000. A linear regression was calculated to observe if there is any correlation between the two biomarkers. Values above the 95th percentile for H-FABP (2.5ng/mL) and the 99th percentile for hsTnT (14ng/L) were considered as positive. Results: At T0, none of the subjects were positive for hsTnT but 35% were positive for H-FABP; at T1, 83% for hsTnT and 100% for H-FABP; at T3, 83% for hsTnT and 96% for H-FABP. At T0, the regression equation was H-FABP T0 = 3.9454 – 0.1001 x hsTnT T0; at T1: H-FABP T1 = 51.838 – 1.7026 x hsTnT T1; at T3: H-FABP T3 = 47.977 – 1.6193 x hsTnT T3. No correlation was observed between the two biomarkers at the different time. Conclusions: We observed a significant increase of H-FABP and hsTnT in runners. These markers are independent to each other. These values could biologically correspond to a heart ischemia. However, we suggested that exercise-induced cardiac hsTnT and H-FABP release is not a marker of exercise-induced pathology but likely a physiologic response to effort or an exercise-induced cardiac remodelling. [less ▲]

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See detailComparison of the Huygens mission and the SM2 test flight for Huygens attitude reconstruction
Sarlette, Alain ULg; Perez-Ayucar, Miguel; Witasse, Olivier et al

Conference (2005, June)

The Huygens probe is the ESA’s main contribution to the Cassini/Huygens mission, carried out jointly by NASA, ESA and ASI. It was designed to descend into the atmosphere of Titan on January 14, 2005 ... [more ▼]

The Huygens probe is the ESA’s main contribution to the Cassini/Huygens mission, carried out jointly by NASA, ESA and ASI. It was designed to descend into the atmosphere of Titan on January 14, 2005, providing surface images and scientific data to study the ground and the atmosphere of Saturn’s largest moon. In the framework of the reconstruction of the probe’s motions during the descent based on the engineering data, additional information was needed to investigate the attitude and an anomaly in the spin direction. Two years before the launch of the Cassini/Huygens spacecraft, in May 1995, a test probe called SM2 (Special Model 2) was dropped in the Earth’s atmosphere from the balloon launch site of Kiruna, Sweden, to verify proper operation during the descent and especially the parachute deployment sequence. It featured a flight standard structure and DCSS (Descent Control SubSystem) and, unlike the Huygens probe, was fully instrumented to monitor the orientation of the descent module (3-axes accelerometers and gyroscopes). We describe how a comparison between the SM2 test flight and the Huygens mission provides some useful information about the Huygens probe’s behavior. After discussing the spin direction, we focus on the tip and tilt. The final conclusions of this comparison at the time of writing are still of qualitative nature, but the results are a starting point for better interpretation of the engineering data in terms of attitude to derive the probe’s orientation. [less ▲]

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See detailComparison of the interactions of a specific neurotoxin (alpha-bungarotoxin) with the acetylcholine receptor in Torpedo californica and Electrophorus electricus membrane preparations.
Leprince, Pierre ULg; Noble, R. L.; Hess, G. P.

in Biochemistry (1981), 20(19), 5565-70

alpha-Bungarotoxin, a snake neurotoxin, binds irreversibly and specifically to the acetylcholine receptor isolated from the electroplax of Electrophorus electricus and Torpedo species and has been an ... [more ▼]

alpha-Bungarotoxin, a snake neurotoxin, binds irreversibly and specifically to the acetylcholine receptor isolated from the electroplax of Electrophorus electricus and Torpedo species and has been an important tool in the study of the receptor-ligand binding mechanism. Two distinct kinetic processes have been observed in studies with membranes from E. electricus. A minimum mechanism for the toxin reaction involves (i) the reversible binding of two toxin molecules to the receptor prior to the irreversible formation of toxin receptor complexes and (ii) a toxin-induced conformational change of the receptor which leads to an increase in the affinity of the receptor binding sites for toxin [Hess, G. P., Bulger, J. E., Fu, J.-j. L., Hindy, E. F., & Silberstein, R. J. (1975) Biochem. Biophys. Res. Commun. 64, 1018-1027]. Only one process has been detected in Torpedo membranes. Here, we determine whether the receptors in Torpedo californica and E. electricus membranes have different properties or whether the measurements and their interpretation were responsible for the different results. Two methods which are frequently used in binding studies to separate free and bound toxin, a CM-52 cellulose minicolumn assay and DE-81 filter disk assay, have been compared. The results obtained indicate that the interaction of toxin with receptor from T. californica is similar to that observed with receptor from E. electricus. The apparent differences which have been reported in the literature are shown to have arisen from the design of the experiments in which T. californica membranes were used. [less ▲]

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See detailComparison of the Internal Energy Distributions of Ions Produced by Different Electrospray Sources
Collette, Caroline ULg; Drahos, Laszlo; De Pauw, Edwin ULg et al

in Rapid Communications in Mass Spectrometry : RCM (1998), 12

The internal energies of the emitted ions can be modulated in an electrospray source through different experimental conditions. However, the fragmentation pattern depends also on conditions that cannot be ... [more ▼]

The internal energies of the emitted ions can be modulated in an electrospray source through different experimental conditions. However, the fragmentation pattern depends also on conditions that cannot be controlled by the operator. These differences make difficult the comparison of the electrospray mass spectra obtained with different mass spectrometers. A method for the calibration of the internal energies of ions produced by an electrospray source has been presented previously to study the influence of experimental conditions on the internal energies of the ions. In this work, new results were obtained with modified values of fragmentation energy taking into account the kinetic shift of thermometer ions. [less ▲]

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See detailComparison of the Iv Pharmacokinetics in Sheep of Miconazole-Cyclodextrin Solutions and a Micellar Solution
Piel, Géraldine ULg; Evrard, Brigitte ULg; Van Hees, Thierry ULg et al

in International Journal of Pharmaceutics (1999), 180(1), 41-5

The pharmacokinetics of miconazole were studied after intravenous administration to six sheep (4 mg/kg) of three aqueous solutions: a marketed micellar solution containing polyoxyl-35 castor oil (Daktarin ... [more ▼]

The pharmacokinetics of miconazole were studied after intravenous administration to six sheep (4 mg/kg) of three aqueous solutions: a marketed micellar solution containing polyoxyl-35 castor oil (Daktarin IV(R)) was compared with two solutions both containing 50 mM lactic acid and a cyclodextrin derivative (100 mM HP-betaCD or 50 mM SBE7-betaCD). The aim of this work was to demonstrate that these cyclodextrin derivatives (CDs) have no effect on the pharmacokinetics of miconazole by comparison with the micellar solution. The plasma concentration time curves have shown that there is no significant difference between the three solutions. [less ▲]

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See detailComparison of the magnetic susceptibility of Belgian and Canadian Frasnian carbonate platforms: Implications for stratigraphic correlation in carbonate strata
Da Silva, Anne-Christine ULg; Weissenberger, John; Potma, KEn et al

in Abstract book - 22th IAS meeting, Opatija, Portugal (2003)

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See detailComparison of the Na and N2+ flashes at Twilight and Dawn.
Swings, Polydore ULg; Nicolet, M.

in Astrophysical Journal (1949), 109

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See detailComparison of the O2-evolving complexes of oscillatoria chalybea with that of different greening stages of higher plant chloroplasts: an amperometric and mass spectrometric study
Bader, K. P.; Franck, Fabrice ULg; Schmid, G. H.

in Argyroudi-Akoyunoglou, J. H. (Ed.) Regulation of Chloroplast Biogenesis (1992)

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See detailComparison of the open-closed field line boundary location inferred using IMAGE-FUV SI12 images and EISCAT radar observations
Hubert, Benoît ULg; Aikio, A. T.; Amm, O. et al

in Annales Geophysicae (2010), 28

We compare the location of the polar cap boundary (PCB) determined using two different techniques, and use them as proxies for the open-closed field line boundary (OCB). Electron temperatures from ... [more ▼]

We compare the location of the polar cap boundary (PCB) determined using two different techniques, and use them as proxies for the open-closed field line boundary (OCB). Electron temperatures from observations of the EISCAT radar facility are used to estimate the latitude of the PCB along the meridian of the EISCAT VHF beam. The second method utilizes global images of proton aurora obtained by the IMAGE satellite FUV SI12 instrument. These methods are applied to three different intervals. In two events, the agreement between the methods is good and the mean of the difference is within the resolution of the observations. In a third event, the PCB estimated from EISCAT data is located several degrees poleward of that obtained from the IMAGE FUV SI12 instrument. Comparison of the reconnection electric field estimated from the two methods shows that high-resolution measurements both in time and space are needed to capture the variations in reconnection electric field during substorm expansion. In addition to the two techniques introduced above to determine the PCB location, we also use a search for the location of the reversal of the east-west component of the equivalent current known as the magnetic convection reversal boundary (MCRB). The MCRB from the MIRACLE magnetometer chain mainly follows the motion of the polar cap boundary during different substorm phases, but differences arise near the Harang discontinuity. [less ▲]

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See detailComparison of the osteorisk, an osteoporosis risk assessment tool in latin america, with the osteoporosis self-assessment tool (OST)
Sen, S. S.; Geling, O.; Messina, O. D. et al

in Osteoporosis International (2002, November), 13(Suppl.3), 27-28

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See detailComparison of the performance of linear resistance and ultrasonic pneumotachometers at rest and during lobeline-induced hyperpnoea
Kästner, S. B. R.; Marlin, D. J.; Roberts, C. A. et al

in Research in Veterinary Science (2000), 68(2), 153-9

The performance of a Fleisch No. 5 pneumotachometer (F), and two commercial ultrasonic pneumotachometers, the BRDL (B) and the Spiroson (S) systems were compared in respect to their use for determination ... [more ▼]

The performance of a Fleisch No. 5 pneumotachometer (F), and two commercial ultrasonic pneumotachometers, the BRDL (B) and the Spiroson (S) systems were compared in respect to their use for determination of ventilatory parameters at rest and during lobeline-induced hyperpnoea. Five clinically healthy Thoroughbred horses were tested with the three pneumotachometers in random order. Respiratory airflow, respired gas concentrations, oesophageal pressures, pressures within the mask systems and arterial blood gases were determined before and during lobeline-induced hyperpnoea. Because measured peak expiratory airflow rates exceeded the stated linear range of the Fleisch pneumotachometer ( approximately +/- 25 l s(-1)) differential pressure-flow curves were determined in vitro over the range of flows recorded in vivo. Expired flows greater than the linear range were corrected according to the derived regression equation. No differences in any of the measured variables among the three systems were present at rest. At peak ventilation of lobeline-induced hyperpnoea mask pressures [Delta P(mask)(mean (SEM)): F: 9.6 (2.8) cm H(2)O, B: 0.8 (0.4) cm H(2)O, S: 1.4 (0.8) cm H(2)O] and end tidal carbon dioxide [ ET CO(2)(mean (SEM)): F: 2. 6 (0.1)%, B: 2.1 (0.2)%, S: 2.1 (0.1)%] were significantly higher in system F. Despite a tendency for respiratory frequency and peak inspired and expired flows, to be lower with system F, no significant differences in the measurements of ventilatory mechanics were detected. In conclusion, the ultrasonic flowmeters pose significantly lower resistive loads onto the respiratory system during ventilation above resting levels than Fleisch No 5 pneumotachometers. However, at the flowrates achieved during lobeline-induced hyperpnoea an in vitro calibration of the differential pressure-flow relationship allows correction for expiratory alinearity in system F. In addition, the performance of the Spiroson flowmeter is accurate in determining ventilatory mechanics at rest and during lobeline-induced hyperpnoea. [less ▲]

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See detailComparison of the performances of different fermentation strategies on cell growth and bacteriocin production by Lactobacillus curvatus CWBI-B28
Ghalfi, Hakim; Benkerroum, Noreddine; Doguiet, Dalié et al

in Journal of the Science of Food and Agriculture (2007), 87

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See detailA comparison of the physical activity promotion strategies adopted by selected secondary schools in three European regions
Van Hoye, Aurélie ULg; Motter, Pascale ULg; Cloes, Marc ULg

in Rossi, T.; Hay, P.; McCuaig, L. (Eds.) et al Proceedings of the 2008 AIESEP World Congress «Sport pedagogy research, policy and practice: International perspectives in physical education and sports coaching. North meets South, East meets West» (2009)

The concept of the ‘active school’ emerged a decade ago as the role with increasing recognition of the role of schools in the promotion of physical activity. The purpose of this paper is to present the ... [more ▼]

The concept of the ‘active school’ emerged a decade ago as the role with increasing recognition of the role of schools in the promotion of physical activity. The purpose of this paper is to present the findings of a study which, drawing on Cale’s ‘Active School’ model, aimed to compare the nature and extent of physical activity promotion in secondary schools in three European regions. In so doing, it aimed to establish whether there were cultural differences in the strategies and approaches adopted by schools. [less ▲]

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See detailComparison of the physicochemical behavior of model oil-in-water emulsions based on different lauric vegetal fats
Anihouvi, Prudent; Danthine, Sabine ULg; Kegelaers, Yves et al

in Food Research International (2013), 53

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See detailComparison of the platelet concentrations obtained in platelet-rich plasma (PRP) between the GPS™ II and GPS™ III systems
Kaux, Jean-François ULg; Le Goff, Caroline ULg; Renouf, Julien et al

in Pathologie Biologie (2011), 59(5), 275-277

Introduction Platelet growth factors are known for their ability to speed up tissue healing (bone, skin, tendons, muscle). Various techniques make it possible to collect this platelet-rich plasma or PRP ... [more ▼]

Introduction Platelet growth factors are known for their ability to speed up tissue healing (bone, skin, tendons, muscle). Various techniques make it possible to collect this platelet-rich plasma or PRP. Methods This study compares the platelet concentrations obtained from five patients using GPS™ III, which has recently come onto the market, with those obtained using GPS™ II. Results and conclusion We obtain a platelet concentration that is six to nine times greater with GPS ™ II and GPS™ III, but there is no significant difference between the concentrations of PRP obtained with the two systems. [less ▲]

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See detailComparison of the proportion of patients potentially treated with an anti-osteoporotic drug using the current criteria of the Belgian national social security and the new suggested FRAX criteria
Bruyère, Olivier ULg; Fossi, Martin; Zegels, Brigitte ULg et al

in Rheumatology International (2013), 33(4), 973-8

To assess the number of anti-osteoporosis treatments that would be reimbursed by the Belgian social security if either FRAX or the current criteria were used to determine access to reimbursement. This is ... [more ▼]

To assess the number of anti-osteoporosis treatments that would be reimbursed by the Belgian social security if either FRAX or the current criteria were used to determine access to reimbursement. This is a retrospective study based on data from 1,000 women randomly selected from an outpatient hospital specialized in bone metabolism in Belgium. Proportions of potentially refunded treatments between FRAX and current criteria were compared. Out of the 1,000 women files, 890 have sufficient information to assess FRAX . In Belgium, current criteria include a bone mineral density (BMD) T score below -2.5 at the lumbar spine, the femoral neck or the total hip and/or at least a prevalent vertebral fracture. Using these criteria, 167 women (18.8 %) would have access to reimbursement. Using the criteria based on the validated Belgian FRAX tool, only 116 women (13.0 %) would have access to reimbursement, meaning that access to reimbursement based on FRAX criteria would reduce by 30 % the anti-osteoporosis drug expenses covered by the national social security. Interestingly, only 65 women out of the 116 (56.0 %) selected with the FRAX criteria were also selected with the current criteria of the national social security. A substantial proportion of individuals that would potentially receive a reimbursement for their treatment using the FRAX criteria do not have access to any refund for their treatment with the current criteria. Since patients identified with the FRAX tool are those with the highest risk profile for future fractures, reappraisals of treatment reimbursement guidelines are expected in Belgium. [less ▲]

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