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See detailComparison of Immune Reconstitution after Hematopoietic Stem Cell Transplantation with Flu-TBI versus TLI-ATG Conditioning
Hannon, Muriel ULg; Humblet-Baron, S.; Graux, C. et al

in Haematologica (2012), 97(Supplement 1), 180

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See detailComparison of Immune Reconstitution after Hematopoietic Stem Cell Transplantation with Flu-TBI versus TLI-ATG Conditioning
Hannon, Muriel ULg; Humblet-Baron, S.; Graux, C. et al

in Belgian Journal of Hematology (2013), Abstracts book(Supplement of 28th General Meeting of the Belgian Hematological Society), 38

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See detailComparison of Immune Reconstitution after Non-myeloablative Hematopoietic Cell Transplantation (HCT) with Flu-TBI versus TLI-ATG Conditioning
Hannon, Muriel ULg; Humblet-Baron, S.; Graux, C. et al

in Belgian Journal of Hematology (2011), Abstracts book(Supplement of 26th General Meeting of the Belgian Hematological Society), 8

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See detailComparison of impacts of dams on the annual maximum flow characteristics in three regulated hydrological regimes in Quebec (Canada).
Assani, A. A.; Stichelbout, E.; Roy, A. G. et al

in Hydrological Processes (2006)

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See detailComparison of impaired subcortico-frontal metabolic networks in normal aging, subcortico-frontal dementia, and cortical frontal demential
Garraux, Gaëtan ULg; Salmon, Eric ULg; Degueldre, Christian ULg et al

in Neuroimage (1999), 10(2), 149-162

Normal aging, progressive supranuclear palsy (PSP), and frontotemporal dementia (FTD) are characterized by different degrees of decline in frontal lobe functions. We used (18)FDG-PET and statistical ... [more ▼]

Normal aging, progressive supranuclear palsy (PSP), and frontotemporal dementia (FTD) are characterized by different degrees of decline in frontal lobe functions. We used (18)FDG-PET and statistical parametric mapping (SPM96) to compare relative subcorticofrontal metabolic impairment at rest in 21 healthy elderly subjects (HES), 20 PSP patients, and 6 FTD patients. When HES were compared to 22 healthy young subjects, widespread decrease in metabolism was observed in bilateral medial prefrontal areas including anterior cingulate cortices, in dorsolateral prefrontal areas, in left lateral premotor area, in Broca's area, and in left insula. In PSP compared to the 43 healthy subjects (HS), we observed subcorticofrontal metabolic impairment including both motor and cognitive neural networks. Impairment of functional connections between midbrain tegmentum and cerebellar, temporal and pallidal regions was demonstrated in PSP as compared to HS. When comparing FTD to HS, glucose uptake was primarily reduced in dorsolateral and ventrolateral prefrontal cortices and in frontopolar and anterior cingulate regions. There was also bilateral anterior temporal, right inferior parietal, and bilateral striatal hypometabolism. Finally, FTD showed more severe striatofrontal metabolic impairment than PSP, while mesencephalothalamic involvement was only observed in PSP. Our data suggest that subcorticofrontal metabolic impairment is distributed in distinct subcorticocortical networks in normal aging, PSP, and FTD. Subcorticofrontal dementia in PSP is related to hypometabolism in discrete frontal areas, which are probably disconnected from certain subcortical structures. The concept of subcortical dementia is reinforced by our data, which show disrupted functional connections between mesencephalon and cerebellar cortex, inferior and medial temporal regions, and pallidum. [less ▲]

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See detailComparison of inflammatory responses after off-pump and on-pump coronary surgery using surface modifying additives circuit
Quaniers, Janine ULg; Leruth, Julie ULg; Albert, Adelin ULg et al

in Annals of Thoracic Surgery (2006), 81(5), 1683-1690

Background. Cardiac surgery is followed by various degrees of inflammation, which have harmful consequences. Because of the central role of extracorporeal circulation ( EC), off- pump coronary bypass ... [more ▼]

Background. Cardiac surgery is followed by various degrees of inflammation, which have harmful consequences. Because of the central role of extracorporeal circulation ( EC), off- pump coronary bypass surgery is deemed preferable. Do different modalities of EC challenge this view? Methods. Four groups of similar patients underwent coronary surgery: ( group 1) on- pump, EC with closed surface modifying additives ( SMA) circuit and no pump suckers ( n = 20); ( group 2) on- pump, EC with open SMA circuit and pump suckers ( n = 20); ( group 3) off- pump ( beating heart) and heparin 3 mg/ kg ( n = 20); ( group 4) off- pump ( beating heart) and heparin 1 mg/ kg ( n = 20). Interleukins ( IL)- 6, IL- 8, IL- 10, myeloperoxidase, elastase, and terminal complex of the complement ( TCC) were analyzed at various times: at induction ( time I); after heparin ( time II); after complete revascularization ( time III); after protamine ( time IV); and 24 hours later ( time V). Results. The TCC was significantly higher in groups 1 and 2 at time III. The pattern of IL- 6 was the same for the four groups. No significant difference in myeloperoxydase content was noted; however, elastase was significantly higher in the two EC ( on- pump) groups. Conclusions. Except for the complement system and elastase, on- pump surgery with SMA- coated circuits did not elicit any greater inflammatory response than off-pump surgery. [less ▲]

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See detailComparison of inhibitory functioning in mild Alzheimer's disease and frontotemporal dementia
Collette, Fabienne ULg; Amieva, Hélène; Adam, Stéphane ULg et al

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2007), 43(7), 866-874

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and ... [more ▼]

Executive dysfunction is frequently reported in Alzheimer's disease (AD) and the frontal variant of frontotemporal dementia (FTD). More specifically, inhibitory dysfunction is observed early in AD and inhibitory deficits are also prominent in patients with FTD. However, few studies have simultaneously explored and compared inhibitory abilities in both degenerative diseases. Consequently, the aim of this study was to compare verbal and motor inhibitory processes in the initial stages of AD and the frontal variant of FTD. Stroop and Go/No-go tasks were administered. The results demonstrate that, on the Go/No-go task, AD and FTD patients do not produce more errors than control subjects. However, both groups are impaired on the Stroop task (mainly with regard to the error score) but do not differ from each other. These results indicate that AD and FTD patients do not present a general impairment of their inhibitory abilities. Moreover, these two kinds of dementia present similar quantitative and qualitative inhibitory impairments on the two tasks, although their patterns of structural and functional cerebral impairments are known to be different. The presence of similar inhibitory deficits despite very different patterns of brain damage is in agreement with the hypothesis that inhibitory dysfunction in the two groups of patients depends on a disconnection process between anterior and posterior cerebral areas, rather than on the presence of focal metabolism decreases in different regions. [less ▲]

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See detailComparison of insulin degludec with insulin glargine in insulin-naive subjects with Type 2 diabetes: a 2-year randomized, treat-to-target trial.
Begin once trial investigators; RADERMECKER, Régis ULg

in Diabetic Medicine : A Journal of the British Diabetic Association (2013)

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See detailComparison of insulin degludec with insulin glargine in insulin-naive subjects with Type 2 diabetes: a 2-year randomized, treat-to-target trial.
BEGIN Once Long Trial Investigators; RADERMECKER, Régis ULg

in Diabetic Medicine : A Journal of the British Diabetic Association (2013)

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See detailComparison of intense nightside shock induced aurora and substorms activity
Meurant, M.; Gérard, Jean-Claude ULg; Blockx, Caroline ULg et al

Conference (2004, December 01)

Variations of the solar wind dynamic pressure induce perturbation of magnetospheric processes. These perturbations frequently induce dayside enhancements of activity with particular features such as low ... [more ▼]

Variations of the solar wind dynamic pressure induce perturbation of magnetospheric processes. These perturbations frequently induce dayside enhancements of activity with particular features such as low latitude proton flash, low latitude arcs and aurora propagating eastward and westward from noon to the night sector. In some cases, these shocks may also induce an enhancement of the nightside activity during which the power precipitated in the night sector may reach values as high as observed during substorms. Various studies have shown that high precipitated powers are more likely during period of negative values of the North - South IMF components. Liou et al (2003) have shown that substorm-like activity is not frequent after a shock and they concluded that a shock may not be considered as a substorm trigger. The question addressed in this study is to know up to what point the substorm like nightside activity triggered by a shock is comparable to a classical substorm. For this purpose, we analyze four events presenting nightside activity morphologically similar to substorms and occurring within a short time (less than 20 minutes) after the arrival of a pressure pulse on the front of the magnetosphere. Different features of these events such as the mean energy of precipitated electrons, the motion of boundaries before and after onset and the power precipitated in the nightside region are compared to typical substorms. Except for the absence of southward motion of activity before onset, shock induced substorms appear very similar to isolated substorms. We investigate the ability of a shock to trigger a substorm during periods characterized by particular conditions. We suggest that the sign of B[SUB]z[/SUB] plays an important role as well as the history of solar wind and interplanetary magnetic field and the resulting state of the magnetosphere. [less ▲]

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See detailComparison of intense nightside shock-induced precipitation and substorm activity
Meurant, M.; Gérard, Jean-Claude ULg; Blockx, Caroline ULg et al

in Journal of Geophysical Research. Space Physics (2005), 110(A7),

[1] Sudden variations of the solar wind dynamic pressure frequently induce dayside enhancements of auroral activity with features such as high-latitude arcs, low-latitude proton flashes, and enhancement ... [more ▼]

[1] Sudden variations of the solar wind dynamic pressure frequently induce dayside enhancements of auroral activity with features such as high-latitude arcs, low-latitude proton flashes, and enhancement of auroral precipitation propagating dawnward and duskward from noon to the night sector. In some cases, these shocks also induce enhanced activity during which the power precipitated into the night sector may reach values as high as observed during substorms. Several studies have shown that the triggering of nightside-enhanced precipitation is more likely during periods of southward interplanetary magnetic field (IMF) components. Early works showed that substorm-like activity is not frequent after a shock and suggested that shocks may not be considered as substorm triggers. We examine up to what point substorm-like nightside activity triggered by a shock is comparable to an isolated substorm. For this purpose, we analyze three events morphologically similar to substorms and occurring within less than 20 min after the arrival of a pressure pulse on the front of the magnetosphere. Different features of these events such as the mean energy of precipitated electrons, the latitudinal motion of boundaries before and after onset, and the power precipitated into the nightside sector are compared with isolated substorms. We conclude that the characteristics of shock-induced substorms appear very similar to those of isolated substorms. Shocks are able to trigger substorms when they hit an unstable magnetosphere. The interpretation is that the perturbation due to the shock induces a substorm by closure of the plasma sheet magnetic field. For the events presented in this study, the instability result from a period of southward IMF or stretching of the magnetic tail induced by a previous shock. [less ▲]

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See detailComparison of intracellular and extracellular particles of the vaccinia virus
Vanderplasschen, Alain ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (1999), 154

The construction of recombinant vaccinia viruses (VV) is definitely a promising approach to develop vaccines for pets. To produce safer VV recombinant vaccines, it is necessary to understand the ... [more ▼]

The construction of recombinant vaccinia viruses (VV) is definitely a promising approach to develop vaccines for pets. To produce safer VV recombinant vaccines, it is necessary to understand the pathogenesis of VV infection. The goal of this study was to compare the biological properties of the extracellular and intracellular infectious particles of VV. Four biological properties were investigated: (i) the binding into cellular receptor(s); (ii) the mechanism of entry; (iii) the resistance to neutralisation by antibodies; (iv) the resistance to complement lysis. The results obtained in this study emphasize the differences existing between the two infectious forms of VV and demonstrate the adaptation of the extracellular particle to its role of virus dissemination in vivo. The results of this study implicate that VV strains used as expression vector in vaccinology should be deleted for genes required for EEV morphogenesis. [less ▲]

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See detailComparison of inulin to urea as dilutional marker of bronchoalveolar lavage in an animal model of asthma
Kirschvink, Nathalie; Fievez, Laurence ULg; Dogné, S. et al

in Proceedings: International Conference of the American Thoracic Society (2001)

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See detailComparison of inulin with urea as dilutional markers of bronchoalveolar lavage in healthy and heaves-affected horses.
Kirschvink, Nathalie; Fievez, Laurence ULg; Dogne, S. et al

in Veterinary Research (2001), 32(2), 145-154

Solute analysis in bronchoalveolar lavage fluid involves the use of dilutional markers to correct for variable recovery of pulmonary epithelial lining fluid (PELF). Urea is the best characterised ... [more ▼]

Solute analysis in bronchoalveolar lavage fluid involves the use of dilutional markers to correct for variable recovery of pulmonary epithelial lining fluid (PELF). Urea is the best characterised endogenous marker, whereas inulin appears to meet the requirements of an exogenous marker. In horses, the use of inulin has never been investigated and the impact of lower airway diseases such as heaves, on PELF recovery is unknown. In this study, five healthy and five heaves-affected horses underwent airway endoscopy and bronchoalveolar lavage. PELF recovery from bronchoalveolar lavage was calculated by the inulin and the urea method. The inulin method was compared to the urea method and differences between healthy and heaves-affected horses were analysed. From a technical and analytical point of view, inulin fulfilled the requirements of a marker of dilution as well as urea. When both healthy and heaves-affected horses groups were pooled together, PELF recovery calculated by the inulin method was significantly higher than by the urea method (6.43+/-4.08% versus 0.789+/-0.299%, P < 0.005). No significant differences were observed between healthy and heaves-affected horses, neither by the inulin nor by the urea method. Inulin did not present major advantages over urea, but the combined use of both markers can improve the standardisation of studies comparing PELF compounds, by providing upper limits (inulin dilution) and lower limits (urea dilution) of PELF recovery. [less ▲]

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See detailComparison of IUE and HST diagnostic of the Jovian aurorae
Thomas, Alexandre ULg; Prangé; Ballester, G. E. et al

in Bulletin of the American Astronomical Society (1994, June 01)

Not Available

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See detailComparison Of Jupiter's Infrared And Uv Aurorae With Simultaneous And Near-simultaneous HST And Ground-based Observations
Lystrup, Makenzie B; Radioti, Aikaterini ULg; Bonfond, Bertrand ULg et al

Conference (2010, October)

Jupiter's UV aurorae have been observed extensively for the last twenty years using the Hubble Space Telescope and the infrared aurorae have been investigated using ground-based telescope observations ... [more ▼]

Jupiter's UV aurorae have been observed extensively for the last twenty years using the Hubble Space Telescope and the infrared aurorae have been investigated using ground-based telescope observations. The two wavelength regimes complement each other; the UV is a tracer of inputs from the magnetosphere while the infrared emissions from the H3+ molecular ion show how the ionosphere responds to those inputs. Between 1995 and 2000 Spectroscopic, J.E.P Connerney & T. Satoh carried out observations with the NSFCAM imaging instrument at the NASA Infrared Telescope Facility. Results from this data set have been published, although the entire data set has not been examined and there has been only limited comparison with the UV. We reanalyze this data set in order to statistically characterize the infrared aurora and compare with the UV. Here we present a detailed study of simultaneous and near-simultaneous observations of the UV (STIS instrument on HST) and infrared northern aurorae made on July 26, 1998 and December 16, 2000. The comparative study addresses the main oval emissions, satellite footprints, and polar aurorae. M. Lystrup is supported by an NSF Astronomy and Astrophysics Postdoctoral Fellowship under award AST-0802021. [less ▲]

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See detailComparison of Kohonen's Self-Organizing Map algorithm and principal component analysis in the exploratory data analysis of a groundwater quality dataset
Peeters, Luk; Dassargues, Alain ULg

(2006)

Groundwater monitoring networks typically yield large, multivariate datasets. Analysis and interpretation of these datasets starts with an exploratory data analysis in order to summarize the available ... [more ▼]

Groundwater monitoring networks typically yield large, multivariate datasets. Analysis and interpretation of these datasets starts with an exploratory data analysis in order to summarize the available data, extract useful information and formulate hypotheses for further research. Exploratory data analysis is mostly focussed on finding related variables and groupings of similar observations. Traditionally multivariate statistical techniques like principal component analysis (PCA) are used for this purpose. In PCA a linear dimensionality reduction of the original, high dimensional dataset is carried out in order to identify orthogonal directions (principal components) of maximum variance in the dataset based on linear combinations of correlated variables. Projections of the original data in the subspace defined by the principal components can be used to identify groups in the data and to reveal relationships between variables (Davis, 1986). In this study, principal component analysis is compared to Kohonen's self-organizing map (SOM) algorithm. The SOM-algorithm is an artificial neural network technique designed to carry out a non-parametric regression process that is mainly used to represent high-dimensional, nonlinearly related data items in a topology-preserving, often two-dimensional display, and to perform unsupervised classification and clustering (Kohonen, 1995). Both PCA and SOM are applied to a hydrochemical dataset from a monitoring network in two sandy, phreatic aquifers in Central Belgium. The monitoring network consists of 47 monitoring wells each equipped with three filters at different depths, in which 14 variables are measured. The first aquifer, the Diest sands aquifer is of Late Miocene age and consists of coarse, glauconiferous sands and sandstones (Laga et al., 2001). The second aquifer, the Brussels sands aquifer, is of Middle Eocene age and is an heterogeneous formation consisting of an alteration of highly and poorly calcareous sands, locally silicified (Laga et al., 2001). Both techniques succeed in distinguishing between both aquifers and reveal the relationships between variables. The main advantage of PCA is the mathematical quantification of correlation between variables and the expression of the original data in the subspace defined by the principal components. The visualization of the SOM-analysis on the other hand allows a straightforward interpretation of the dataset structure in which even non-linear relationships between variables can be identified. Additionally, the SOM-algorithm can handle a limited amount of missing values in the dataset, contrary to PCA. [less ▲]

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