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See detailComorbidity and disease status based risk stratification of outcomes among patients with acute myeloid leukemia or myelodysplasia receiving allogeneic hematopoietic cell transplantation.
Sorror, Mohamed L; Sandmaier, Brenda M; Storer, Barry E et al

in Journal of Clinical Oncology (2007), 25(27), 4246-54

PURPOSE: Retrospective studies have shown similar survival among patients with acute myeloid leukemia (AML) and myelodysplasia (MDS) after nonmyeloablative compared with myeloablative conditioning ... [more ▼]

PURPOSE: Retrospective studies have shown similar survival among patients with acute myeloid leukemia (AML) and myelodysplasia (MDS) after nonmyeloablative compared with myeloablative conditioning. Refined risk stratification is required to design prospective trials. PATIENTS AND METHODS: We stratified outcomes among patients with AML (n = 391) or MDS (n = 186) who received either nonmyeloablative (n = 125) or myeloablative (n = 452) allogeneic hematopoietic cell transplantation (HCT) based on comorbidities, as assessed by a HCT-specific comorbidity index (HCT-CI), as well as disease status. Patients receiving nonmyeloablative conditioning were older, more frequently pretreated, more often received unrelated grafts, and more often had HCT-CI scores of 3 compared with patients who received myeloablative conditioning. RESULTS: Patients with HCT-CI scores of 0 to 2 and either low or high disease risks had probabilities of overall survival at 2 years of 70% and 57% after nonmyeloablative conditioning compared with 78% and 50% after myeloablative conditioning, respectively. Patients with HCT-CI scores of 3 and either low or high disease risks had probabilities of overall survival of 41% and 29% with nonmyeloablative conditioning compared with 45% and 24% with myeloablative regimens, respectively. After adjusting for pretransplantation differences, stratified outcomes were not significantly different among patients receiving nonmyeloablative compared with myeloablative conditioning, with the exception of lessened nonrelapse mortality (hazard ratio, 0.50; P = .05) in the highest risk group. CONCLUSION: Patients with low comorbidity scores could be candidates for prospective randomized trials comparing nonmyeloablative and myeloablative conditioning regardless of disease status. Additional data are required for patients with low-risk diseases and high comorbidity scores. Novel antitumor agents combined with nonmyeloablative HCT should be explored among patients with high comorbidity scores and advanced disease. [less ▲]

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See detailComorbidity in Autism Spectrum
Philippe, Paule ULg; Scholl, Jean-Marc ULg; Jacques, Jessica ULg

in Psychiatria Danubina (2010), 22(S1), 158-60

Detailed reference viewed: 39 (6 ULg)
See detailComorbidity in migraine
Schoenen, Jean ULg; Dodick, DW; Sándor, P

Book published by Wiley-Blackwell Publishing Ltd (2011)

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See detailCompact Air Separation Technology For In-Flight Oxygen Collection
Bizzarri, Didier; Hendrick, Patrick; Heintz, N. et al

in 15th AIAA International Space Planes and Hypersonic Systems and Technologies Conference (2008, April)

In the context of an ESA-funded study on an air separation device intended to provide in-flight Oxygen Collection capability to future launchers, experimental and system level investigations are performed ... [more ▼]

In the context of an ESA-funded study on an air separation device intended to provide in-flight Oxygen Collection capability to future launchers, experimental and system level investigations are performed. The project consortium is run by the Université Libre de Bruxelles and includes the Belgian Defence, Techspace Aero (Safran Group) and Liège university among others. In-flight Oxygen Collection has already been described in previous publications, mainly as a conceptual approach. The improvement potentials have been studied and possible uses of the technology go beyond the concept presented here. That is in the aerospace field and also outside, in a much wider range of applications. Hardware work on compact separation are seldom described. As the setup was nearing completion, design know how improved. The last problems were solved and the setup was made fully operational and subject to testing. The following review summarizes the work with latest information on the technological and experimental aspects. In the vehicles using air separation and collection, the cooling capacity of the fuel, liquid hydrogen, is used during a first air breathing phase of the flight to enrich in oxygen and liquefy a fraction of the incoming air. Compact and light weight heat exchanger, coupled to the separator, perform that task. The main advantages of the concept, applied in our preferred concept to TSTO’s, are a much reduced take off mass, a reduced mass for the liquid rocket engines and a much increased operational flexibility in terms of reachable orbit and launch window. Moreover, unlike scramjet propulsion, separation does not rely on high technology material but on readily available material and hardware used with proper design know how and appropriate expertise. The experimental setup development follows a somewhat different route. Liquid and saturated gaseous air are prepared in special heat exchangers before the separator can be fed, the cold source used being liquid nitrogen. The experimental separator itself is, in reality, a 'section' of a real separator. Disposing of the fluids in this machine deserves special care, since pressure has to be controlled while a liquid seal has to be kept stable in most of the operating conditions. Some workarounds had to be developed for that last problem and different solutions were kept available during the testing. Separating is an aspect, interactively measuring -required to tune to proper performance- is another. The operating fluids, that are supposed to be liquid or gaseous in the simple modeling, are in practice often two phase, which is difficult to asses during test and which can strongly impact flow and concentration measurements. High temperature gradients, low temperatures had to be considered for mechanical, sealing and bearing design, nevertheless, strong uncertainty remained before separation results are presented and demonstrate the concept. Most result went above expectations and much further compactification potentials are present. The know how gathered from testing experience allows to foresee improvement directions, both in the global concept and the detail design of a real unit. Those results will allow to extrapolate the real potentials of the separator design developed by our laboratory to the bigger units required for a real concept. [less ▲]

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See detailCompact and portable holographic camera using photorefractive crystals. Application in various metrological problems
Georges, Marc ULg; Scauflaire, Véronique; Lemaire, Philippe

in Applied Physics B : Lasers & Optics (2001), 72

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See detailCompact and Portable Photorefractive Holographic Camera in View of High Accuracy and Dynamic Objects Displacements and Deformations Measurement
Georges, Marc ULg; Lemaire, Philippe

in Proceedings of the PHOTOMEC'99-ETE'99 European Workshop (1999, November)

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See detailCompact holographic camera based on photorefractive crystals and application in interferometry
Georges, Marc ULg; Scauflaire, Véronique; Lemaire, Philippe

in Optical Materials (2001), 18

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See detailCompact integrated surface plasmon resonance spectroscopic sensor platform with on-chip self-referencing
Hastanin, Juriy ULg; Fleury-Frenette, Karl ULg; Lenaerts, Cedric ULg et al

in Proceeding of the International Conference on Surface Plasmon Photonics (SPP6): Ottawa, Canada, May 2013 (2013, May)

We present the SPR_CD spectroscopic biosensor design experimentally investigated by our research group. The implemented sensor platform is dedicated to droplet biochemical analysis involving multichannel ... [more ▼]

We present the SPR_CD spectroscopic biosensor design experimentally investigated by our research group. The implemented sensor platform is dedicated to droplet biochemical analysis involving multichannel detection format. [less ▲]

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See detailCompact photorefractive holographic camera and its applications in interferometry
Georges, Marc ULg; Scauflaire, Véronique; Lemaire, Philippe ULg

in Nolte, D.; Salamo, G.; Siahmakoun, A. (Eds.) et al Photorefractive Effects, Materials, and Devices (2001, July)

A compact holographic interferometer that uses a photorefractive crystal of the sillenite family as holographic recording medium is presented. It was developed to provide high accuracy displacement ... [more ▼]

A compact holographic interferometer that uses a photorefractive crystal of the sillenite family as holographic recording medium is presented. It was developed to provide high accuracy displacement measurements of scattering objects, together with a high degree of flexibility, portability and versatility in function of the application. We briefly discuss the main technical aspects leading to a compact device. We present a couple of recent applications, among which the coefficient of thermal expansion of composite structures is measured, piezosheets calibration and fingerprint detection. [less ▲]

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See detailCompact quadratizations of nonlinear binary optimization problems
Crama, Yves ULg; Rodriguez Heck, Elisabeth ULg

Conference (2014, March 25)

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See detailCompact star clusters of the LMC H ii region N11 C
Heydari-Malayeri, Mohammad; Royer, Pierre; Rauw, Grégor ULg et al

in Astronomy and Astrophysics (2000), 361

Based on imaging and spectroscopy obtained at the ESO NTT telescope and using an efficient image analysis algorithm, we study the core of the LMC OB association LH 13, particularly the two compact stellar ... [more ▼]

Based on imaging and spectroscopy obtained at the ESO NTT telescope and using an efficient image analysis algorithm, we study the core of the LMC OB association LH 13, particularly the two compact stellar clusters Sk-66[SUP]deg[/SUP]41, and HNT in the H ii, region N 11C. We resolve Sk-66[SUP]deg[/SUP]41, into 15 components and for the first time the HNT cluster into 70 stars, and derive photometry for the members. Moreover, from medium resolution spectroscopy we determine the spectral types for sixteen stars in N 11C. We compare the color-magnitude diagrams of the clusters with that of the field stars and discuss the cluster ages. With an age of ~ ,100 Myr, the HNT cluster appears significantly older than the very young (<= 5 Myr) Sk-66[SUP]deg[/SUP]41, starburst. We suggest that most of the `field' O-stars in the core of N 11C have actually been ejected from Sk-66[SUP]deg[/SUP]41, through dynamical interactions in the compact cluster. The properties of the Sk-66[SUP]deg[/SUP]41, and HNT clusters suggest that we are viewing different star formation regions lying at different distances along the same line of sight. Based on observations obtained at the European Southern Observatory, La Silla, Chile [less ▲]

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See detailA compact system of small planets around a former red giant star
Charpinet, Stéphane; Fontaine, Gilles; Brassard, Pierre et al

in Nature (2011), 480

Planets that orbit their parent star at less than about one astronomical unit (1AU is the Earth-Sun distance) are expected to be engulfed when the star becomes a red giant. Previous observations have ... [more ▼]

Planets that orbit their parent star at less than about one astronomical unit (1AU is the Earth-Sun distance) are expected to be engulfed when the star becomes a red giant. Previous observations have revealed the existence of post-red-giant host stars with giant planets orbiting as close as 0.116AU or with brown dwarf companions in tight orbits, showing that these bodies can survive engulfment. What has remained unclear is whether planets can be dragged deeper into the red-giant envelope without being disrupted and whether the evolution of the parent star itself could be affected. Here we report the presence of two nearly Earth-sized bodies orbiting the post-red-giant, hot B subdwarf star KIC 05807616 at distances of 0.0060 and 0.0076AU, with orbital periods of 5.7625 and 8.2293 hours, respectively. These bodies probably survived deep immersion in the former red-giant envelope. They may be the dense cores of evaporated giant planets that were transported closer to the star during the engulfment and triggered the mass loss necessary for the formation of the hot B subdwarf, which might also explain how some stars of this type did not form in binary systems. [less ▲]

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See detailLa compaction des sols agricoles en Wallonie
Destain, Marie-France ULg

Book published by SPW (2014)

Dans nos pays industrialisés, l’agriculture fait appel à des machines de plus en plus lourdes. Lorsque des charges élevées sont appliquées sur des sols sensibles, une compaction du sol peut se produire ... [more ▼]

Dans nos pays industrialisés, l’agriculture fait appel à des machines de plus en plus lourdes. Lorsque des charges élevées sont appliquées sur des sols sensibles, une compaction du sol peut se produire conduisant à des diminutions de rendements suite aux difficultés que rencontrent les racines pour prélever l’eau et les nutriments et à la perturbation de l’activité de la pédofaune. Au niveau environnemental, du fait de la compaction, l’infiltration de l’eau dans le sol est réduite, principalement dans l’horizon superficiel. Une accumulation de l’eau à la surface du sol avec un accroissement des écoulements latéraux et du ruissellement peut apparaître. Il en résulte une augmentation des risques d’inondation et de pollution de surface provenant de l’application d’intrants. Le risque d’érosion sur des sols en pente, même faible, est également accru. En Europe, on estime que 32 % des couches profondes de sol sont largement dégradées. A l’inverse de l’érosion ou de la salinisation qui montrent des signes visibles de dégradation, les effets néfastes de la compaction ne sont pas immédiatement perceptibles. Du fait que la compaction des horizons profonds (au-delà de 30 cm) est un phénomène difficilement réversible par régénération naturelle et que les méthodes de restauration artificielles ne sont pas toujours couronnées de succès, l’Union Européenne considère la compaction comme l’un des facteurs majeurs de la dégradation physique des sols. Le projet de Directive européenne COM(2006)232 amendé par la note 16157/07 du 14 décembre 2007 établit un cadre général pour la protection des sols. Ce projet prévoit notamment que les Etats membres, dont fait partie la Belgique, identifient sur leur territoire les zones susceptibles de présenter des processus de dégradation du sol (érosion, perte de matière organique, compaction, salinisation, contamination et perte de biodiversité). Une fois les zones à risque identifiées, les Etats membres doivent proposer des objectifs de réduction des risques ainsi que des mesures concrètes permettant de les atteindre. Ils sont libres de fixer leurs propres objectifs et de décider comment et quand les atteindre. Le projet SoCo a établi une cartographie de la sensibilité des sols européens à la compaction. Cependant, étant donné sa faible résolution, cette carte ne permet pas de se faire une idée précise de la situation en Wallonie. La Direction générale opérationnelle Agriculture, Ressources naturelles et Environnement du SPW a donc décidé de mettre en œuvre une étude pour analyser de manière plus précise les risques de compaction des sols en Wallonie. [less ▲]

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See detailLa compaction des sols forestiers en Wallonie
Destain, Marie-France ULg

Book published by SPW (2014)

Dans nos pays industrialisés, l’exploitation forestière fait appel à des machines de plus en plus lourdes pour assurer la vidange des coupes et le débardage des grumes. Lorsque des charges élevées sont ... [more ▼]

Dans nos pays industrialisés, l’exploitation forestière fait appel à des machines de plus en plus lourdes pour assurer la vidange des coupes et le débardage des grumes. Lorsque des charges élevées sont appliquées sur des sols sensibles, une compaction du sol peut se produire entraînant une réduction de porosité, avec des conséquences néfastes sur la vitalité des peuplements. Au niveau environnemental, du fait de la compaction, l’infiltration de l’eau dans le sol est réduite, principalement dans l’horizon superficiel. Une accumulation de l’eau à la surface du sol avec un accroissement des écoulements latéraux et du ruissellement peut apparaître. Il en résulte une augmentation des risques d’inondation et de pollution de surface provenant de l’application d’intrants. Le risque d’érosion sur des sols en pente, même faible, est également accru. En Europe, on estime que 32 % des couches profondes de sol sont largement dégradées. A l’inverse de l’érosion ou de la salinisation qui montrent des signes visibles de dégradation, les effets néfastes de la compaction ne sont pas immédiatement perceptibles. Du fait que la compaction des horizons profonds (au-delà de 30 cm) est un phénomène difficilement réversible par régénération naturelle et que les méthodes de restauration artificielles ne sont pas toujours couronnées de succès, l’Union Européenne considère la compaction comme l’un des facteurs majeurs de la dégradation physique des sols. Le projet de Directive européenne COM(2006)232 amendé par la note 16157/07 du 14 décembre 2007 établit un cadre général pour la protection des sols. Ce projet prévoit notamment que les Etats membres, dont fait partie la Belgique, identifient sur leur territoire les zones susceptibles de présenter des processus de dégradation du sol (érosion, perte de matière organique, compaction, salinisation, contamination et perte de biodiversité). Une fois les zones à risque identifiées, les Etats membres doivent proposer des objectifs de réduction des risques ainsi que des mesures concrètes permettant de les atteindre. Ils sont libres de fixer leurs propres objectifs et de décider comment et quand les atteindre. Le projet SoCo a établi une cartographie de la sensibilité des sols européens à la compaction. Cependant, étant donné sa faible résolution, cette carte ne permet pas de se faire une idée précise de la situation en Wallonie. Par ailleurs, le Code Forestier Wallon entré en vigueur le 13 septembre 2008 prévoit explicitement l’interdiction d’occasionner des dégâts au sol qui pourraient avoir des conséquences à long terme sur la vitalité des peuplements. Dans ce cadre, la Direction générale opérationnelle Agriculture, Ressources naturelles et Environnement du SPW a décidé de mettre en œuvre une étude pour analyser de manière plus précise les risques de compaction des sols en Wallonie. [less ▲]

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See detailcompaction dynamics of magnetized powder
Lumay, Geoffroy ULg; Dorbolo, Stéphane ULg; Vandewalle, Nicolas ULg

in Physical Review. E : Statistical, Nonlinear, and Soft Matter Physics (2009), 80

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See detailCompaction Dynamlics of Wet Granular Assemblies
Fiscina, J. E.; Lumay, Geoffroy ULg; Ludewig, François ULg et al

in Physical Review Letters (2010), 105

The extremely slow compaction dynamics of wet granular assemblies is studied experimentally. The cohesion, due to capillary bridges between neighboring grains, is tuned using different liquids having ... [more ▼]

The extremely slow compaction dynamics of wet granular assemblies is studied experimentally. The cohesion, due to capillary bridges between neighboring grains, is tuned using different liquids having specific surface tension values. The compaction dynamics of a cohesive packing obeys an inverse logarithmic law, like most dry random packings. However, the characteristic relaxation time 􏰌 grows strongly with cohesion. A model, based on free volume kinetic equations and the presence of a capillary energy barrier, is able to reproduce quantitatively the experimental curves. [less ▲]

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See detailCompaction of anisotropic granular materials: Experiments and simulations
Lumay, Geoffroy ULg; Vandewalle, Nicolas ULg

in Physical Review E (2004), 70(5, Pt 1), 51314

We present both experimental and numerical investigations of compaction in granular materials composed of rods. As a function of the particles size and with respect to the container diameter, we have ... [more ▼]

We present both experimental and numerical investigations of compaction in granular materials composed of rods. As a function of the particles size and with respect to the container diameter, we have observed large variations of the asymptotic packing volume fraction. The relevant parameter is the ratio between the rod length l and the tube diameter D. Even the compaction dynamics remains unchanged for various particle lengths, and a transition between 3d and 2d ordering for grain orientations is observed for l/D= 1. A toy model for the compaction of needles on a lattice is also proposed. This toy model gives a complementary view of our experimental results and leads to behaviors similar to experimental ones. [less ▲]

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See detailCompaction of granular materials: experiments and contact dynamics simulations
Lumay, Geoffroy ULg; Ludewig, François ULg; Vandewalle, Nicolas ULg

in Journal of Physics: Conference Series (2006), 40

We present an original experimental study of the slow compaction dynamics for two- dimensional isotropic granular systems. Compaction dynamics is measured at three different scales : the macroscopic scale ... [more ▼]

We present an original experimental study of the slow compaction dynamics for two- dimensional isotropic granular systems. Compaction dynamics is measured at three different scales : the macroscopic scale through the normalized packing fraction ˜ ρ, the mesoscopic scale through the normalized fraction ˜ φ of domains ideally ordered in the system, and the microscopic scale through the grain mobility μ. The domains ideally ordered are found to obey a growth process dominated by the displacement of domain boundaries. We present also preliminary results of three-dimensional simulations with a model of contact dynamics. These results allow to discuss the difference between the two-dimensional and the three-dimensional cases. [less ▲]

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See detailCompaction of granular mixtures
Ludewig, François ULg; Vandewalle, Nicolas ULg; Dorbolo, Stéphane ULg

in Granular Matter (2006), 8(2), 87-91

We propose a lattice model for studying the compaction of granular mixtures under taps. Two granular species are considered: small grains with low mobilities and T-shaped grains characterized by a larger ... [more ▼]

We propose a lattice model for studying the compaction of granular mixtures under taps. Two granular species are considered: small grains with low mobilities and T-shaped grains characterized by a larger ability to move. When those grains are mixed together, the compaction dynamics is mainly controlled by the volume fraction x of the small grains. Segregation have been found on the top layers of the pile. The grain mobilities have been studied for different values of the volume fraction x. An effective grain mobility has been defined for the mixture. This mobility is given by the linear combination of the mobility of both pure species minus a non-linear interaction term. Finally, the compaction speed depends on the fraction of the anisotropic grains. [less ▲]

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See detailCompactly supported wavelets in Sobolev spaces of integer order
Bastin, Françoise ULg; Laubin, P.

in Applied & Computational Harmonic Analysis (1997), 4(1), 51-57

We present a construction of regular compactly supported wavelets in any Sobolev space of integer order. It is based on the existence and suitable estimates of filters defined from polynomial equations ... [more ▼]

We present a construction of regular compactly supported wavelets in any Sobolev space of integer order. It is based on the existence and suitable estimates of filters defined from polynomial equations. We give an implicit study of these filters and use the results obtained to construct scaling functions leading to multiresolution analysis and wavelets. Their regularity increases linearly with the length of their supports as in the L(2) case. One technical problem is to prove that the intersection of the scaling spaces is reduced to 0. This is solved using sharp estimates of Littlewood-Paley type. (C) 1997 Academic Press, Inc. [less ▲]

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