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See detailCombinaison fixe perindopril-amlodipine (Coveram®) dans le traitement de l'hypertension artérielle et de l'insuffisance coronaire.
Scheen, André ULg; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (2009), 64(4), 223-227

Coveram® is a new fixed combination of an angiotensin converting enzyme inhibitor, perindopril, and a calcium antagonist, amlodipine. This new medication is indicated for the treatment of arterial ... [more ▼]

Coveram® is a new fixed combination of an angiotensin converting enzyme inhibitor, perindopril, and a calcium antagonist, amlodipine. This new medication is indicated for the treatment of arterial hypertension and/or stable coronary heart disease. Such fixed combination of two molecules that have been extensively evaluated according to evidence-based medicine offers the advantage of an excellent efficacy, associated with a good tolerance profile, and favours patient’s compliance. The marketing of different formulations of Coveram® combining various dosages allows easy adjustment and titration of each of the components according to the individual patient’s characteristics. [less ▲]

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See detailCombination of actor’s play training and assertiveness program to reduce difficulties in self-affirmation: A preliminary study.
Wagener, Aurélie ULg; Delvaux, Muriel ULg; Sarto, Danielle et al

in 2013 BAPS Annual Meeting : Conference booklet (2013, May 28)

BACKGROUND. Difficulties in assertiveness are often reported by individuals suffering from various psychological problems involving anxiety, depression. Cognitive and behavioral therapeutic procedures ... [more ▼]

BACKGROUND. Difficulties in assertiveness are often reported by individuals suffering from various psychological problems involving anxiety, depression. Cognitive and behavioral therapeutic procedures have already proven their effectiveness in helping these patients. The aim of our study was to test the efficacy of new therapeutic procedure, inspired by the third wave of behavioral and cognitive psychotherapies. METHOD. Our study used an actor’s play training combined with an assertiveness program which comprised ten sessions: five of which were animated by an actress and five by a psychologist-psychotherapist. Each actor play’s session was given alternatively with a psychoeducation’s session. Twenty subjects participated in this program. They fulfilled these pre and post-test assessments: social self-efficacy questionnaire, self-affirmation scales, self-esteem scale, communication scale, anxiety and depression scales. Repeated measures’ ANOVAs have been used to compare pre and post-test results. RESULTS. Results showed statistically significant improvements on each dependent variable, except for the Communication Scale. The higher effects appeared for Beck Depression Inventory and Social Self-efficacy Questionnaire which presented an effect size of 0,74 and 0,56, respectively. Scores on STAI-A and B and on Self-affirmation Scale were over the effect size’s threshold. However, these improvements don’t attain control group’s scores reported in the scientific literature. DISCUSSION. The results highlighted that our program is effective in reducing difficulties in assertiveness. [less ▲]

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See detailCombination of actor's play training and assertiveness program to reduce difficulties in self-affirmation: A preliminary study.
Wagener, Aurélie ULg; Delvaux, Muriel ULg; Sarto, Danielle et al

Poster (2013, May 28)

BACKGROUND. Difficulties in assertiveness are often reported by individuals suffering from various psychological problems involving anxiety, depression. Cognitive and behavioral therapeutic procedures ... [more ▼]

BACKGROUND. Difficulties in assertiveness are often reported by individuals suffering from various psychological problems involving anxiety, depression. Cognitive and behavioral therapeutic procedures have already proven their effectiveness in helping these patients. The aim of our study was to test the efficacy of new therapeutic procedure, inspired by the third wave of behavioral and cognitive psychotherapies. METHOD. Our study used an actor’s play training combined with an assertiveness program which comprised ten sessions: five of which were animated by an actress and five by a psychologist-psychotherapist. Each actor play’s session was given alternatively with a psychoeducation’s session. Twenty subjects participated in this program. They fulfilled these pre and post-test assessments: social self-efficacy questionnaire, self-affirmation scales, self-esteem scale, communication scale, anxiety and depression scales. Repeated measures’ ANOVAs have been used to compare pre and post-test results. RESULTS. Results showed statistically significant improvements on each dependent variable, except for the Communication Scale. The higher effects appeared for Beck Depression Inventory and Social Self-efficacy Questionnaire which presented an effect size of 0,74 and 0,56, respectively. Scores on STAI-A and B and on Self-affirmation Scale were over the effect size’s threshold. However, these improvements don’t attain control group’s scores reported in the scientific literature. DISCUSSION. The results highlighted that our program is effective in reducing difficulties in assertiveness. [less ▲]

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See detailCombination of capillary electrophoresis, molecular modelling and nuclear magnetic resonance to study the interaction mechanisms between single-isomer anionic cyclodextrin derivatives and basic drug enantiomers in a methanolic background electrolyte.
Servais, Anne-Catherine ULg; Rousseau, Anne; Dive, Georges ULg et al

in Journal of Chromatography. A (2012), 1232

In order to improve our knowledge of the mechanisms of enantiomer recognition pattern in nonaqueous systems, an approach combining nonaqueous CE (NACE), molecular modelling and NMR was undertaken ... [more ▼]

In order to improve our knowledge of the mechanisms of enantiomer recognition pattern in nonaqueous systems, an approach combining nonaqueous CE (NACE), molecular modelling and NMR was undertaken. Bupivacaine and propranolol were selected as model compounds and their interactions with two single-isomer highly charged beta-CD derivatives, namely heptakis(2,3-di-O-methyl-6-O-sulfo)-beta-CD (HDMS-beta-CD) and heptakis(2,3-di-O-acetyl-6-O-sulfo)-beta-CD (HDAS-beta-CD), were studied. The CD-bupivacaine complexes were evaluated by 2-D Rotating-frame Overhauser Effect SpectroscopY (ROESY) experiments. From these experiments, it can be assumed that inclusion complexes are not formed, whatever the CD derivative used. Molecular modelling was performed at the RHF/MINI-1 or B3LYP/6-31G(d) level. External as well as inclusion type complexes with the alkyl chain of propranolol into both CD cavities were located. Interaction energies calculated for bupivacaine and propranolol correlated with the enantiomer migration order observed in the NACE experiments using both anionic CD derivatives. The interaction of propranolol with HDMS-beta-CD or HDAS-beta-CD gives rise to a family of external and inclusion complexes in which some are more probably obtained. [less ▲]

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See detailCombination of different techniques and multi-scale approach to understand CO2 budget in a temperate beech forest
Longdoz, Bernard; Epron, Daniel; Goffin, Stéphanie ULg et al

Conference (2010, November)

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See detailCombination of electrografting and atom-transfer radical polymerization for making the stainless steel surface antibacterial and protein antiadhesive
Ignatova, Miléna; Voccia, Samuel; Gilbert, Bernard ULg et al

in Langmuir (2006), 22(1), 255-262

A two-step "grafting from" method has been successfully carried out, which is based on the electrografting of polyacrylate chains containing an initiator for the atom transfer radical polymerization (ATRP ... [more ▼]

A two-step "grafting from" method has been successfully carried out, which is based on the electrografting of polyacrylate chains containing an initiator for the atom transfer radical polymerization (ATRP) of 2-(tert-butylamino)ethyl methacrylate (TBAEMA) or copolymerization of TBAEMA with either monomethyl ether of poly(ethylene oxide) methacrylate (PEOMA) or acrylic acid (AA) or styrene. The chemisorption of this type of polymer brushes onto stainless steel surfaces has potential in orthopaedic surgery. These films have been characterized by ATR-FTIR, Raman spectroscopy, atomic force microscopy (AFM), and measurement of contact angles of water. The polymer formed in solution by ATRP and that one detached on purpose from the surface have been analyzed by size exclusion chromathography (SEC) and H-1 NMR spectroscopy. The strong adherence of the films onto stainless steel has been assessed by peeling tests. AFM analysis has shown that addition of hydrophilic comonomers to the grafted chains decreases the surface roughness. According to dynamic quartz crystal microbalance experiments, proteins (e.g., fibrinogen) are more effectively repelled whenever copolymer brushes contain neutral hydrophilic (PEOMA) co-units rather than negatively charged groups (PAA salt). Moreover, a 2- to 3-fold decrease in the fibrinogen adsorption is observed when TBAEMA is copolymerized with either PEOMA or AA rather than homopolymerized or copolymerized with styrene. Compared to the bare stainless steel surface, brushes of polyTBAEMA, poly (TBAEMA-co-PEOMA) and poly(TBAEMA-co-AA) decrease the bacteria adhesion by 3 to 4 orders of magnitude as revealed by Gram-positive bacteria S. aureus adhesion tests. [less ▲]

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See detailCombination of electrografting and layer-by-layer deposition: an efficient way to tailor polymer coatings of (semi)-conductors
Charlot, Aurélia; Gabriel, Sabine ULg; Detrembleur, Christophe ULg et al

in Chemical Communications (2007), (44), 4656-4658

This communication reports on a novel, simple and highly versatile concept, which consists in combining the advantages of two complementary and relevant techniques (i) electrografting and (ii) layer-by ... [more ▼]

This communication reports on a novel, simple and highly versatile concept, which consists in combining the advantages of two complementary and relevant techniques (i) electrografting and (ii) layer-by-layer deposition process with the goal to tailor strongly adhering coatings to (semi)-conducting surfaces imparting them with tunable specific properties. [less ▲]

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See detailCombination of Electrografting and Ring-Opening Metathesis Polymerization: An Efficient Way to Prepare Polynorbornene Brushes on Conducting Substrates
Detrembleur, Christophe ULg; Jérôme, Christine ULg; Claes, Michaël et al

in Angewandte Chemie (International ed. in English) (2001), 40(7), 1268-1271

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See detailCombination of electrografting with controlled polymerization: building of anti-bacterial surfaces
Voccia, Samuel; Ignatova, Miléna; Gilbert, Bernard ULg et al

Conference (2005, June 01)

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See detailCombination of experimental and simulated small scale solar air-conditioning system
Thomas, Sébastien ULg; Hennaut, Samuel ULg; Andre, Philippe ULg

in EUROSUN 2010, International conference on solar heating, cooling and buildings, 28 September - 1 October 2010, Graz, Austria (2010, October 01)

It is now clearly assumed that solar assisted air conditioning is able to decrease CO2 production of building operation. One way to evaluate the energy savings potential is the simulation of ... [more ▼]

It is now clearly assumed that solar assisted air conditioning is able to decrease CO2 production of building operation. One way to evaluate the energy savings potential is the simulation of airconditioning systems. On the other hand, it is also crucial to assess system performance by experimentations. The operation of a solar cooling system in its real environment is considered here. The objective is to evaluate if sun radiation in our region (Western Europe – Belgium) in summer 2009 is enough for feeding an adsorption chiller, in other words to find experimentally the solar fraction of a solar air-conditioning system in our region. Residential application suits with equipment available in our laboratory. A combination of experimentation and simulation is used because of the lack of sorption chiller in our laboratory facilities. Hot loops are measured while cold and rejection loops are simulated. Thirty-one days were measured; energy flows analysis on the whole period reveals a theoretical solar fraction of nearly 100% but a real solar fraction of 31%. Issues related to the test implementation are emphasized and explained in this paper. [less ▲]

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See detailCombination of FMdC, Tirapazamine (SR4233) and irradiation in vitro
COUCKE, Philippe ULg; Cottin, E; Stern, S et al

in International Journal of Radiation, Oncology, Biology, Physics (2000), 46(3),

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See detailCombination of Genomic and Proteomic Approaches to Characterize the Symbiotic Population of the Banana Aphid (Hemiptera: Aphididae)
De Clerck, Caroline ULg; Tsuchida, Tsutomu; Massart, Sébastien ULg et al

in Environmental Entomology (2014)

Aphids are known to live in symbiosis with speciÞc bacteria called endosymbionts that have positive or negative impacts on their hosts. In this study, six banana aphid (Pentalonia nigronervosa Coquerel ... [more ▼]

Aphids are known to live in symbiosis with speciÞc bacteria called endosymbionts that have positive or negative impacts on their hosts. In this study, six banana aphid (Pentalonia nigronervosa Coquerel) strains from various geographical origins (Gabon, Madagascar, and Burundi) were screened to determine their symbiotic content, using complementary genomic (16S rDNA sequencing and speciÞc polymerase chain reaction) and proteomic (two-dimensional difference gel electrophoresis coupled with protein identiÞcation by matrix assisted laser desorption-ionization time-of-ßight mass spectrometry) approaches. Despite the geographical heterogeneity, the combined methods allowed us to identify the same two symbionts in the six aphids strains tested: Buchnera aphidicola and Wolbachia. Although B. aphidicola is found in almost all aphid species, the systematic presence of Wolbachia in banana aphids is particularly interesting, as this bacterium usually has a low prevalence in aphid species. Phylogenetic analyses showed that the Wolbachia sp. strain found in P. nigronervosa was very similar to the strain present in aphids of the genus Cinara, known to have developed a strong and long-term symbiotic association with Wolbachia. The high level of asexual reproduction in P. nigronervosa could be linked to the presence of Wolbachia, but its prevalence also suggests that this symbiotic bacterium could play a more essential role in its aphid host. [less ▲]

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See detailCombination of genotype, pedigree, local and foreign information
Vandenplas, Jérémie ULg; Colinet, Frédéric ULg; Gengler, Nicolas ULg

in Book of Abstracts of the 64th Annual Meeting of the European Federation of Animal Science (2013, August)

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See detailCombination of illuminants and its effect on colour rendering
Embrechts, Jean-Jacques ULg

in Lighting Research & Technology (1988), 20(1)

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