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See detailLe clair-obscur des socialistes liégeois
Verjans, Pierre ULg

in Politique : Revue de Débats (2009), 62

Les résultats électoraux du parti socialiste à Liège en 2009 illustre une double tendance, l'une tournée vers la médiatisation d'une personnalité populaire, l'autre axée sur une volonté d'utiliser les ... [more ▼]

Les résultats électoraux du parti socialiste à Liège en 2009 illustre une double tendance, l'une tournée vers la médiatisation d'une personnalité populaire, l'autre axée sur une volonté d'utiliser les outils publics comme moyens d'attirer les investisseurs de capitaux. [less ▲]

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See detailClairs-obscurs Tensions du regard au XIXe siècle
Havelange, Carl ULg

in Havelange, Carl (Ed.) Cultures visuelles au XIXe siècle (1) (2000)

Detailed reference viewed: 14 (1 ULg)
See detailLes clandestins de l’Eurégio. Quelques contrefaçons de Liège et de Maestricht conservées à Luxembourg
Droixhe, Daniel ULg

in Deitz, L. (Ed.) Tempus edax rerum : Le bicentenaire de la Bibliothèque nationale de Luxembourg (1798 – 1998) (2001)

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See detailCLANIMAE:Climatic and Anthropogenic Impacts on African Ecosystems. Final Report Phase 1 (2007-2008)
Verschuren, Dirk; Plisnier, Pierre-Denis; Hugues, Harold et al

Report (2009)

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See detailCLARA WARD & THE FAMOUS WARD SINGERS ( CD sleeve notes)
Sacré, Robert ULg

in GOSPEL FRIEND (Ed.) CLARA WARD & THE FAMOUS WARD SINGERS In Memory of Willa-Ward-Royster PN-1508 (2013)

The Ward Singers are considered as one of the best -if not the best- female gospel group ever. Gospel Friend and Per Notini gathered 25 rare tracks recorded between 1949-1958. The notes tell the story of ... [more ▼]

The Ward Singers are considered as one of the best -if not the best- female gospel group ever. Gospel Friend and Per Notini gathered 25 rare tracks recorded between 1949-1958. The notes tell the story of the group and of the recordings. [less ▲]

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See detailClarifier les dimensions socio-économiques et politiques de l'agroécologie : au delà des principes, des compromis
Dumont, Antoinette; Stassart, Pierre M ULg; Vanloqueren, Gaetan et al

Conference (2014)

Le concept d’agroécologie est de plus en plus mobilisé en Europe. Toutefois, les dimensions socio-économiques et politiques de cette alternative au modèle productiviste restent encore peu qualifiées dans ... [more ▼]

Le concept d’agroécologie est de plus en plus mobilisé en Europe. Toutefois, les dimensions socio-économiques et politiques de cette alternative au modèle productiviste restent encore peu qualifiées dans le monde académique. La présente étude contribue à clarifier les principes socio-économiques et politiques de l’agroécologie, en mettant les principes identifiés dans la littérature grise et scientifique à l’épreuve de l’étude qualitative de deux systèmes alimentaires belges : Agribio, une coopérative céréalière ; les Grosses Légumes un réseau de ménages, producteurs et citoyens membres qui organisent la production et la distribution de paniers de légumes. Des entretiens semi-directifs ont été effectués auprès des différents acteurs de ces systèmes alimentaires. Ils ont été analysés à la lumière de la théorie de la justification de Boltanski et Thévenot afin de mettre en évidence les principes que les acteurs rencontrés se donnent et tentent de mettre en application dans les différents projets qu’ils réalisent. Les principaux résultats obtenus sont explicités par l’analyse de quatre compromis (qui concernent les systèmes de commercialisation des deux systèmes alimentaires, un Système de Garantie Participative mis en place par les Grosses Légumes et la meunerie d’Agribio), plus spécifiquement étudiés via les objets qui matérialisent ces compromis et les controverses qui les remettent en question. Les deux études de cas illustrent l’écart qui existe entre les principes qui décrivent un horizon vers lequel l’agroécologie tend et les principes mis concrètement en oeuvre par les acteurs de terrain au travers des différentes trajectoires de transition. [less ▲]

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See detailCLASIFICACIÓN ACÚSTICA DE PAVIMENTOS PARA CAPAS DE RODADURA CON CÁMARA SEMIANECOICA
Paje, S.E.; Luong, Jeanne ULg

in XV Congreso Ibero Latino Americano do Asfalto (2010)

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See detailThe CLASS (CLinical and Angiographic analysis with a cobalt alloy coronary Stent (Driver(TM)) in stable and unstable angina pectoris) study
Legrand, Victor ULg; Kelbaek, H.; Hauptmann, K. E. et al

in European Heart Journal (2004), 25(Suppl. S), 669-670

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See detailClass A β -Lactamases as Versatile Scaffolds to Create Hybrid Enzymes: Applications from Basic Research to Medicine
Huynen, Céline ULg; Filée, Patrice; Matagne, André ULg et al

in BioMed Research International (2013), 2013

Designing hybrid proteins is a major aspect of protein engineering and covers a very wide range of applications frombasic research to medical applications. This review focuses on the use of class A 𝛽 ... [more ▼]

Designing hybrid proteins is a major aspect of protein engineering and covers a very wide range of applications frombasic research to medical applications. This review focuses on the use of class A 𝛽-lactamases as versatile scaffolds to design hybrid enzymes (referred to as 𝛽-lactamase hybrid proteins, BHPs) in which an exogenous peptide, protein or fragment thereof is inserted at various permissive positions.We discuss how BHPs can be specifically designed to create bifunctional proteins, to produce and to characterize proteins that are otherwise difficult to express, to determine the epitope of specific antibodies, to generate antibodies against nonimmunogenic epitopes, and to better understand the structure/function relationship of proteins. [less ▲]

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See detailClass II histone deacetylases: versatile regulators.
Verdin, Eric; Dequiedt, Franck ULg; Kasler, Herbert G

in Trends in Genetics (2003), 19(5), 286-93

Histone acetylation and deacetylation play essential roles in modifying chromatin structure and regulating gene expression in eukaryotes. Histone deacetylases (HDACs) catalyze the deacetylation of lysine ... [more ▼]

Histone acetylation and deacetylation play essential roles in modifying chromatin structure and regulating gene expression in eukaryotes. Histone deacetylases (HDACs) catalyze the deacetylation of lysine residues in the histone N-terminal tails and are found in large multiprotein complexes with transcriptional co-repressors. Human HDACs are grouped into three classes based on their similarity to known yeast factors: class I HDACs are similar to the yeast transcriptional repressor yRPD3, class II HDACs to yHDA1 and class III HDACs to ySIR2. In this review, we focus on the biology of class II HDACs. These newly discovered enzymes have been implicated as global regulators of gene expression during cell differentiation and development. We discuss their emerging biological functions and the molecular mechanisms by which they are regulated. [less ▲]

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See detailClass IIa histone deacetylases: conducting development and differentiation.
Martin, Maud ULg; Kettmann, Richard ULg; Dequiedt, Franck ULg

in International Journal of Developmental Biology (2009), 53(2-3), 291-301

The emergence of specialized cell types and their organisation into organs and tissues involve the temporal modulation of many genes that are essential for coordinating the correct timing of instructive ... [more ▼]

The emergence of specialized cell types and their organisation into organs and tissues involve the temporal modulation of many genes that are essential for coordinating the correct timing of instructive signals. These transcriptional changes are orchestrated with a precision that reminds that of a classical symphony. Extracellular signals are transmitted to key integrators, which then orchestrate activation or repression of specific genes. In the last decade, class IIa HDACs have emerged as crucial regulators in various developmental and differentiation processes. This review focuses on the latest studies that have provided new insights into the biological functions of class IIa HDACs and discusses important aspects of their regulation. Elucidating cellular and molecular mechanisms by which functions of class IIa HDACs are modulated could potentially lead to new therapeutic opportunities for various diseases. [less ▲]

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See detailClass IIa histone deacetylases: regulating the regulators.
Martin, Maud ULg; Kettmann, Richard ULg; Dequiedt, Franck ULg

in Oncogene (2007), 26(37),

n the last decade, the identification of enzymes that regulate acetylation of histones and nonhistone proteins has revealed the key role of dynamic acetylation and deacetylation in various cellular ... [more ▼]

n the last decade, the identification of enzymes that regulate acetylation of histones and nonhistone proteins has revealed the key role of dynamic acetylation and deacetylation in various cellular processes. Mammalian histone deacetylases (HDACs), which catalyse the removal of acetyl groups from lysine residues, are grouped into three classes, on the basis of similarity to yeast counterparts. An abundance of experimental evidence has established class IIa HDACs as crucial transcriptional regulators of various developmental and differentiation processes. In the past 5 years, a tremendous effort has been dedicated to characterizing the regulation of these enzymes. In this review, we summarize the latest discoveries in the field and discuss the molecular and structural determinants of class IIa HDACs regulation. Finally, we emphasize that comprehension of the mechanisms underlying class IIa HDAC functions is essential for potential therapeutic applications. [less ▲]

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See detailA Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part I: Theoretical Development
Gallego-Garrido, Jon; Dimitriadis, Grigorios ULg; Wright, Jan Robert

in International Journal of Rotating Machinery (2007), 2007

Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of ... [more ▼]

Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. Although the fundamentals of the technique are simple, the analysis of data obtained in the presence of simultaneously occurring synchronous resonances is problematic. A class of autoregressive-based methods for the analysis of blade tip timing data from assemblies undergoing two simultaneous resonances has been developed. It includes approaches that assume both sinusoidal and general blade tip responses. The methods can handle both synchronous and asynchronous resonances. An exhaustive evaluation of the approaches was performed on simulated data in order to determine their accuracy and sensitivity. One of the techniques was found to perform best on asynchronous resonances and one on synchronous resonances. Both methods yielded very accurate vibration frequency estimates under all conditions of interest. [less ▲]

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See detailA Class of Methods for the Analysis of Blade Tip Timing Data from Bladed Assemblies Undergoing Simultaneous Resonances—Part II: Experimental Validation
Gallego-Garrido, Jon; Dimitriadis, Grigorios ULg; Carrington, Ian B. et al

in International Journal of Rotating Machinery (2007), 2007

Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. In Part I of this work a class of methods for the analysis of blade tip timing data from bladed assemblies ... [more ▼]

Blade tip timing is a technique for the measurement of vibrations in rotating bladed assemblies. In Part I of this work a class of methods for the analysis of blade tip timing data from bladed assemblies undergoing two simultaneous synchronous resonances was developed. The approaches were demonstrated using data from a mathematical simulation of tip timing data. In Part II the methods are validated on an experimental test rig. First, the construction and characteristics of the rig will be discussed. Then, the performance of the analysis techniques when applied to data from the rig will be compared and analysed. It is shown that accurate frequency estimates are obtained by all the methods for both single and double resonances. Furthermore, the recovered frequencies are used to calculate the amplitudes of the blade tip responses. The presence of mistuning in the bladed assembly does not affect the performance of the new techniques. [less ▲]

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See detailClass V β Tubulin during the development of the organ of Corti in rat
Renauld, Justine ULg; Thelen, Nicolas ULg; Johnen, Nicolas ULg et al

Poster (2013, September 13)

In eutherian mammals, the organ responsible for the transduction of sound waves into nerve impulses is called the organ of Corti. This structure located within the cochlea, a portion of the inner ear, is ... [more ▼]

In eutherian mammals, the organ responsible for the transduction of sound waves into nerve impulses is called the organ of Corti. This structure located within the cochlea, a portion of the inner ear, is composed by two types of cells: sensory hair cells and non-sensory supporting cells. All these cells are distributed according to a specific arrangement along the whole length of the cochlea. A feature of the organ of Corti’s supporting cell is the presence of an abundant cytoskeleton. This one is mainly composed of microtubules, structures make up by tubulin heterodimers. The heterodimers consist of one molecule of α tubulin and one molecule of β tubulin. β tubulin isotypes are highly conserved in evolution and differ by only a few amino acid residues, implying that the isotypes may have functional significance. Organ of Corti’s supporting cells are constituted by class V β-tubulin, a minor mammalian tubulin (Bhattacharya et al., 2008). Moreover, their microtubules are formed by 15 protofilaments instead of the canonical 13, a unique fact among vertebrates (Banerjee et al., 2008). Such a configuration of protofilaments has been observed in C. elegans’ neurons which are responsible for the mechanosensory sense of touch (Bounoutas et al., 2009). It was also shown that these 15 protofilaments microtubules were essential to the proper functioning of these mechanosensory neurons (Bounoutas et al., 2009). Here we present the spatiotemporal localization of class V β-tubulin during the development of the organ of Corti in rats from embryonic day 18 (E18) until P25 (25th postnatal day). For this purpose, we have used immunolabelings on cryosections of whole cochlea. Our preliminary results demonstrate that class V β-tubulin has a unique distribution in the cochlea, being restricted to supporting cells, especially in pillar cells. [less ▲]

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See detailLa classe de langue comme observatoire et laboratoire d'un apprentissage expérientiel des langues étrangères à travers la pédagogie par projet
Simons, Germain ULg

in Etudes & Travaux (1999), (3), 67-84

G. Simons begins by pointing out the difficulties encountered by many language teachers in trying to provide students with real communication situations. According to the author, the methodological ... [more ▼]

G. Simons begins by pointing out the difficulties encountered by many language teachers in trying to provide students with real communication situations. According to the author, the methodological approach which consists in asking students to "imagine they are Mr Smith" hardly conceals its formal interest. Furthemore, it should be completed with an experiential approach aiming at an articulation of the active experimentation of the foreign language in the here and now as well as the analysis of the functioning of the language as a system. The preparation and exploitation of a pedagogical project for a linguistic stay provides the foreign language course with a concrete aim and a real linguistic material, which it often lacks. In analysing and comparing the linguistic data from students and native speakers in real and identical communication situations, the language teacher can test the interlanguage of his students. Moreover, this process of comparison enables the language teacher to make students "notice the gap" between their language production and that of native speakers. This "notice the gap" technique transforms the traditional language class into an observatory and laboratory of the foreign language and of the interlanguage. [less ▲]

Detailed reference viewed: 49 (7 ULg)