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See detailA capillary Archimedes’ screw
Darbois-Texier, Baptiste ULg; Dorbolo, Stéphane ULg

Conference (2014, November 23)

As used by Egyptians for irrigation and reported by Archimedes, a screw turning inside a hollow pipe can pull out a fluid againt gravity. At a centimetric scale, an analagous system can be found with a ... [more ▼]

As used by Egyptians for irrigation and reported by Archimedes, a screw turning inside a hollow pipe can pull out a fluid againt gravity. At a centimetric scale, an analagous system can be found with a drop pending on a rotating spiral which is tilted toward the horizontal. The ascent of the drop to the top of the spiral is considered and a theoretical model based on geometrical considerations is proposed. The climb of the drop is limited by the fluid deposition on the screw at high capillary number and by a centrifugation phenomenon. We find out the range of fluid proprities and spiral characteristics for which an ascending motion of the drop is possible. Finally we discuss the efficiency of such system to extract a fluid from a bath at a centrimetric scale. [less ▲]

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See detailCapillary electrophoresis in the context of drug discovery.
Farcas, Elena ULg; Pochet, Lionel; Crommen, Jacques ULg et al

in Journal of Pharmaceutical & Biomedical Analysis (2017)

Capillary Electrophoresis is a very efficient and resolutive separation technique used for many years in the analytical field. Despite all its assets, CE remains poorly used in drug discovery. This can be ... [more ▼]

Capillary Electrophoresis is a very efficient and resolutive separation technique used for many years in the analytical field. Despite all its assets, CE remains poorly used in drug discovery. This can be explained by the relatively low number of experienced CE practitioners, the maturity of HPLC in the pharmaceutical industry and some intrinsic limitations of the technique. The objective of this review is to focus our attention on recent developments of this technique in three different drug discovery areas: bioassays, drug-plasma interactions and drug metabolism studies. These developments were based on two important abilities of CE: the capacity to measure non-covalent interactions in solution and the ability to use a portion of the capillary as a reactor while the rest of the capillary is used for the separation of the product of the reaction. [less ▲]

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See detailCapillary electrophoresis method to determine siRNA complexation with cationic liposomes
Furst, Tania ULg; Bettonville, Virginie ULg; Farcas, Elena ULg et al

in Electrophoresis (2016)

Small interfering RNA (siRNA) inducing gene silencing has great potential to treat many human diseases. To ensure effective siRNA delivery, it must be complexed with an appropriate vector, generally ... [more ▼]

Small interfering RNA (siRNA) inducing gene silencing has great potential to treat many human diseases. To ensure effective siRNA delivery, it must be complexed with an appropriate vector, generally nanoparticles. The nanoparticulate complex requires an optimal physiochemical characterization and the complexation efficiency has to be precisely determined. The methods usually used to measure complexation are gel electrophoresis and RiboGreen® fluorescence-based assay. However, those approaches are not automated and present some drawbacks such as the low throughput and the use of carcinogenic reagents. The aim of this work is to develop a new simple and fast method to accurately quantify the complexation efficiency. In this research, capillary electrophoresis (CE) was used to determine the siRNA complexation with cationic liposomes. The short-end injection mode applied enabled siRNA detection in less than 5 min. Moreover, the CE technique offers many advantages compared to the other classical methods. It is automated, does not require sample preparation and expensive reagents. Moreover, no mutagenic risk is associated to CE approach since no carcinogenic product is used. Finally, this methodology can also be extended to the characterization of other types of nanoparticles encapsulating siRNA, such as cationic polymeric nanoparticles. [less ▲]

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See detailCapillary electrophoresis-mass spectrometry, an attractive tool for drug bioanalysis and biomarker discovery
Servais, Anne-Catherine ULg; Crommen, Jacques ULg; Fillet, Marianne ULg

in Electrophoresis (2006), 27(13), 2616-2629

The coupling of CE with MS detection, a relatively recent hyphenated technique, has gained increasing respect in the field of bioanalytical applications over the past few years. The first part of this ... [more ▼]

The coupling of CE with MS detection, a relatively recent hyphenated technique, has gained increasing respect in the field of bioanalytical applications over the past few years. The first part of this review presents CE-MS applications dealing with drug bioanalysis, including forensic analysis and metabolism studies. Practical considerations to achieve a robust and sensitive CE-MS coupling are also presented. It is indeed essential to strictly control some critical electrospray parameters, such as the sheath liquid composition and flow rate, the nebulizing gas pressure as well as the capillary outlet position. The second part of the review critically describes the applications of CE coupled on-line to MS for the identification of biomarkers in body fluids for diagnostic purposes. Since the sample preparation procedures strongly differ according to the intended use (drug bioanalysis or biomarker discovery), they are discussed separately, taking into account the particular properties of plasma and urine matrices. [less ▲]

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See detailCapillary electrophoretic and nuclear magnetic resonance studies on the opposite affinity pattern of propranolol enantiomers towards various cyclodextrins
Servais, Anne-Catherine ULg; Rousseau, Anne ULg; Fillet, Marianne ULg et al

in Journal of Separation Science (2010), 33

In the present study the migration order of the propranolol enantiomers with various native CDs and neutral and charged CD derivatives was examined in capillary electrophoresis (CE). The reversal of the ... [more ▼]

In the present study the migration order of the propranolol enantiomers with various native CDs and neutral and charged CD derivatives was examined in capillary electrophoresis (CE). The reversal of the enantiomer migration order was observed due to sulfation of β-CD on its primary hydroxy groups. The structures of intermolecular selector-selectand temporary diastereomeric associates in solution were elucidated based on 1D rotating frame nuclear Overhauser effect spectroscopy (1D ROESY) experiments. Major structural differences were observed between the propranolol complexes with native β-CD and heptakis(6-O-sulfo)-β-CD. [less ▲]

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See detailCapillary rise in foams under microgravity
Caps, Hervé ULg; Cox, S. J.; Decauwer, H. et al

in Colloids and Surfaces A : Physicochemical and Engineering Aspects (2005), 261(1-mars Sp. Iss. SI), 131-134

The motion of liquid into a foam under low-gravity conditions is studied both experimentally and theoretically. The foam is confined to two dimensions in a Hele-Shaw cell and the liquid fraction measured ... [more ▼]

The motion of liquid into a foam under low-gravity conditions is studied both experimentally and theoretically. The foam is confined to two dimensions in a Hele-Shaw cell and the liquid fraction measured by image analysis. The foam imbibition is shown to be a diffusive process. Two models are analysed, corresponding to the limits of rigid and mobile interfaces in the Plateau borders. Liquid fraction profiles are compared to experimental ones. (c) 2004 Elsevier B.V. All rights reserved. [less ▲]

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See detailCapillary-driven two-dimensional buoyancy in vertical soap films
Adami, Nicolas ULg; Caps, Hervé

in Europhysics Letters [=EPL] (2014)

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See detailCapire gli attegiamenti nei confronti degli omogenitori in Belgio
Scali, Thérèse ULg

Scientific conference (2014, April 10)

La situazione sociale per i genitori gay e lesbiche in Belgio. I predittori degli atteggiamenti positivi e negativi verso l’omogenitorialità. Le famiglie Rainbow in Belgio: cosa permette la legge? Miti e ... [more ▼]

La situazione sociale per i genitori gay e lesbiche in Belgio. I predittori degli atteggiamenti positivi e negativi verso l’omogenitorialità. Le famiglie Rainbow in Belgio: cosa permette la legge? Miti e stereotipi sulle famiglie omogenitoriali. Perché alcuni Belgi non sostengono gli omogenitori? Il ruolo del « benessere » del bambino. Cosa si può fare? [less ▲]

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See detailCapital formation in Belgium 1900-1995.
Geerkens, Eric ULg

in Revue Belge de Philologie et d'Histoire (2005), 83(2), 519-523

Detailed reference viewed: 41 (8 ULg)
See detailCapital humain et dualisme sur le marché du travail
De La Croix, David; Docquier, Frédéric; Guyot, Jean-Luc et al

Book published by De Boeck (2002)

L'objectif de cet ouvrage est d'explorer les interactions économiques majeures entre le capital humain, le fonctionnement du marché du travail et la croissance régionale. La première partie traite du ... [more ▼]

L'objectif de cet ouvrage est d'explorer les interactions économiques majeures entre le capital humain, le fonctionnement du marché du travail et la croissance régionale. La première partie traite du dualisme sur le marché du travail en Belgique et dans les pays développés. La deuxième aborde les liens fondamentaux entre capital humain et emploi. La troisième explore les implications macroéconomiques en matière de croissance et de convergence régionale. Une annexe statistique illustre l'état du marché du travail et de l'offre de qualifications en Belgique et dans les régions européennes. Cet ouvrage intéressera tout particulièrement les professeurs et étudiants en sciences économiques, les décideurs politiques, les institutions publiques, les collectivités locales. [less ▲]

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See detailCapital humain, emploi et revenus du travail: Belgique, 1992
Docquier, Frédéric; Laurent, Sébastien; Perelman, Sergio ULg

in Cahiers Economiques de Bruxelles (1999), (161), 77-103

L’objet de ce papier est de mettre en évidence, pour un échantillon de travailleurs salariés masculins, le rôle de l’éducation et, de façon plus large, du capital humain sur l’emploi et la formation des ... [more ▼]

L’objet de ce papier est de mettre en évidence, pour un échantillon de travailleurs salariés masculins, le rôle de l’éducation et, de façon plus large, du capital humain sur l’emploi et la formation des salaires en Belgique. A partir de données individuelles, on estime économétriquement les relations entre d’une part, le diplôme obtenu et, d’autre part, le fait d’avoir un emploi ainsi que le niveau de rémunération correspondant. Les résultats obtenus confirment de manière statistiquement significative ces relations en mettant en évidence non seulement le rôle du niveau des études mais également celui du type d’enseignement (général, technique, professionnel) poursuivie sur le rendement en capital humain. On montre aussi que la dimension régionale a une importance non négligeable sur le taux d’occupation; par contre, elle s’avère être totalement inopérante sur la formation des salaires. [less ▲]

Detailed reference viewed: 53 (17 ULg)
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See detailCapital income taxation when inherited wealth is not observable
Cremer, H.; Pestieau, Pierre ULg; Rochet, J. C.

in Journal of Public Economics (2003), 87(11), 2475-2490

This paper extends the Atkinson-Stiglitz model of direct and indirect taxation to a dynamic setting with two unobservable characteristics: productive ability and inherited wealth. Bequests are motivated ... [more ▼]

This paper extends the Atkinson-Stiglitz model of direct and indirect taxation to a dynamic setting with two unobservable characteristics: productive ability and inherited wealth. Bequests are motivated by the 'joy of giving'. A child's inheritance is a random variable with a probability distribution that depends on his parent's investment in a 'bequest technology'. Public borrowing is assumed and implies the modified golden rule. We study the optimal tax policy when two instruments are available: a non-linear (wage) income tax and a proportional tax on capital income. We show that the second instrument ought, in general, to be used but that the tax rate is not necessarily positive. However, a positive tax rate is more likely when there is a positive correlation between inherited wealth and innate ability. (C) 2002 Elsevier B.V. All rights reserved. [less ▲]

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See detailCapital social
Dozo, Björn-Olav ULg

in Glinoer, Anthony; Saint-Amand, Denis (Eds.) Lexique Socius (2013)

Detailed reference viewed: 54 (0 ULg)
See detailLe capital social : essai de cartographie wallonne
Jacquemain, Marc ULg

Scientific conference (2006, October)

The conference synthesizes what different survey shows about the nature and amount of social capital across Wallonia

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See detailLe capital social : essai de cartographie wallonne
Jacquemain, Marc ULg

in Fédéralisme - Régionalisme (2006), 6

The paper tries to assess how various measures of social capital vary locally within Wallonia

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See detailLe capital social : une introduction
Jacquemain, Marc ULg

in Houard, Jean; Jacquemain, Marc (Eds.) Capital social et dynamique régionale (2006)

The text presents the main articulations within social capital theory : formal and informal, thin and thick, bonding, bridging and linking social capital, with a word about the theory of the "dark side ... [more ▼]

The text presents the main articulations within social capital theory : formal and informal, thin and thick, bonding, bridging and linking social capital, with a word about the theory of the "dark side". It also adresses the question of what is at stake in this theory. Then, the text introduces the main themes of the book : the links between social capital and social cohesion, gender, education, media, entrepeneurship [less ▲]

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See detailLe capital social est-il soluble dans les médias : le rôle de la télévision, d'Internet et des modes d'information
Jacquemain, Marc ULg

in Houard, Jean; Jacquemain, Marc (Eds.) Capital social et dynamique régionale (2006)

The chapter explores the way various kinds of media consuming may affect the main dimensions of social capital : network of social relations, political involment (and among it electoral turnout ... [more ▼]

The chapter explores the way various kinds of media consuming may affect the main dimensions of social capital : network of social relations, political involment (and among it electoral turnout), socializing. What appears is a difference between the media : while an intensive use of television tends to deter social capital (but the certainly not in the huge proportion sometimes assumed), reading newspapers acts exactly in the opposite way. As for Internet, it seems that it depends of the kind of use, but, on the whole it is mainly a support to polititical involvement. The models control effects of age, education and gender. [less ▲]

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See detailCapital social et dynamique régionale
Houard, Jean; Jacquemain, Marc ULg

Book published by De Boeck Université (2006)

After broadly introducing the various concepts around the notion of social capital, the book explores rather deeply five related fields through survey data collected at the level of frenchspeaking belgium ... [more ▼]

After broadly introducing the various concepts around the notion of social capital, the book explores rather deeply five related fields through survey data collected at the level of frenchspeaking belgium : education, media, social cohesion, gender, entrepreneurship [less ▲]

Detailed reference viewed: 47 (10 ULg)