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See detailClinical and Radiological Aspects of Dysplastic Gangliocytoma (Lhermitte-Duclos Disease): A Report of Two Cases with Review of the Literature
Milbouw, G.; Born, J. D.; Martin, Didier ULg et al

in Neurosurgery (1988), 22(1, Pt 1), 124-8

Two cases of Lhermitte-Duclos disease confirmed by biopsy are reported. Review of the 58 published cases shows that the disease can manifest itself only by signs of increased intracranial pressure ... [more ▼]

Two cases of Lhermitte-Duclos disease confirmed by biopsy are reported. Review of the 58 published cases shows that the disease can manifest itself only by signs of increased intracranial pressure. Cerebellar symptoms are not constant. Computed tomographic (CT) scans suggest the diagnosis by showing a posterior fossa lesion, iso- and hypodense, partially calcified, and not enhanced by contrast medium. Magnetic resonance imaging (MRI) seems to define limits of the lesion better than CT scanning and could improve the surgical approach. Surgical excision of the lesion is the only satisfactory treatment. The postoperative prognosis is usually favorable. [less ▲]

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See detailClinical and ultrasonographic predictors of joint replacement for knee osteoarthritis: results from a large, 3-year, prospective EULAR study
Conaghan, P. G.; D'Agostino, M. A.; Le Bars, M. et al

in Annals of the Rheumatic Diseases (2010), 69

OBJECTIVES: To determine clinical and ultrasonographic predictors of joint replacement surgery across Europe in primary osteoarthritis (OA) of the knee. METHODS: This was a 3-year prospective study of a ... [more ▼]

OBJECTIVES: To determine clinical and ultrasonographic predictors of joint replacement surgery across Europe in primary osteoarthritis (OA) of the knee. METHODS: This was a 3-year prospective study of a painful OA knee cohort (from a EULAR-sponsored, multicentre study). All subjects had clinical evaluation, radiographs and ultrasonography (US) at study entry. The rate of knee replacement surgery over the 3-year follow-up period was determined using Kaplan-Meier survival data analyses. Predictive factors for joint replacement were identified by univariate log-rank test then multivariate analysis using a Cox proportional-hazards regression model. Potential baseline predictors included demographic, clinical, radiographic and US features. RESULTS: Of the 600 original patients, 531 (88.5%), mean age 67+/-10 years, mean disease duration 6.1+/-6.9 years, had follow-up data and were analysed. During follow-up (median 3 years; range 0-4 years), knee replacement was done or required for 94 patients (estimated event rate of 17.7%). In the multivariate analysis, predictors of joint replacement were as follows: Kellgren and Lawrence radiographic grade (grade > or =III vs <III, hazards ratio (HR) = 4.08 (95% CI 2.34 to 7.12), p<0.0001); ultrasonographic knee effusion (> or =4 mm vs <4 mm) (HR = 2.63 (95% CI 1.70 to 4.06), p<0.0001); knee pain intensity on a 0-100 mm visual analogue scale (> or =60 vs <60) (HR = 1.81 (95% CI 1.15 to 2.83), p=0.01) and disease duration (> or =5 years vs <5 years) (HR=1.63 (95% CI 1.08 to 2.47), p=0.02). Clinically detected effusion and US synovitis were not associated with joint replacement in the univariate analysis. CONCLUSION: Longitudinal evaluation of this OA cohort demonstrated significant progression to joint replacement. In addition to severity of radiographic damage and pain, US-detected effusion was a predictor of subsequent joint replacement. [less ▲]

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See detailClinical application of a noninvasive multi-electrode array EMG for the recording of single motor unit activity.
RAMAEKERS, Vincent ULg; Disselhorst-Klug, C.; Schneider, J. et al

in Neuropediatrics (1993), 24(3), 134-8

Using a recently developed noninvasive EMG recording technique with multi-electrode arrays we investigated the pattern and distribution of motor unit action potentials (MUAP) following maximal voluntary ... [more ▼]

Using a recently developed noninvasive EMG recording technique with multi-electrode arrays we investigated the pattern and distribution of motor unit action potentials (MUAP) following maximal voluntary contraction of the musculus abductor pollicis brevis. An additional parameter, i.e. muscular conduction velocity (CV) in single motor units, was calculated from the multi-electrode array EMG recordings. From 63 healthy children of various age the normal EMG pattern and CV were derived and compared to the EMG of diagnosed patients known to suffer from Duchenne muscular dystrophy and from spinal muscular atrophy. In normal individuals the muscular CV in neonates was lowest at 1-2 m/s and gradually reached a plateau of 2.9-4 m/s from the age of 4 years onwards. The EMG in 31 children with Duchenne muscular dystrophy showed an abnormal pattern with low amplitude action potentials. In 30 out of 31 patients a significantly lower muscular CV was found. In 10 children with spinal muscular atrophy the EMG showed action potentials of abnormally large amplitude and a reduced recruitment of firing motor units. The muscular CV remained within the normal range. Compared to classical needle EMG the application of this new noninvasive EMG technique in children is painless and offers an easy-to-handle diagnostic tool to differentiate between neuromuscular diseases of denervating or of myopathic origin. [less ▲]

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See detailClinical application of the heterogeneity of creatine kinase isoenzyme MM
Chapelle, Jean-Paul ULg

Conference (1985, October)

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See detailClinical applications of assessment of airway inflammation using induced sputum
Pavord, I. D.; Sterk, P. J.; Hargreave, F. E. et al

in European Respiratory Journal (2002), 20(Suppl. 37), 40-43

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See detailClinical applications of cardiac troponins
Chapelle, Jean-Paul ULg

in Acta Clinica Belgica (2001), 56

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See detailClinical applications of cardiac troponins
Chapelle, Jean-Paul ULg

Conference (2001, October 27)

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See detailClinical applications of microspheres in embolization and chemoembolization: a comprehensive review and perspectives
Flandroy, P. M. J.; Grandfils, Christian ULg; Jérôme, Robert ULg

in Rolland, A (Ed.) Pharmaceutical Particulate Carriers in Medical Applications (1993)

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See detailClinical applications of pinhole single photon emission tomography
Seret, Alain ULg; Hustinx, Roland ULg

in Current Medical Imaging Reviews (2006), 2(3), 347-352

For some planar scintigraphic explorations, like thyroid or hip, the pinhole collimator is usually preferred to the usual parallel hole collimators because it allows a superior resolution. Progress in 3D ... [more ▼]

For some planar scintigraphic explorations, like thyroid or hip, the pinhole collimator is usually preferred to the usual parallel hole collimators because it allows a superior resolution. Progress in 3D tomography reconstruction methods allows single photon emission tomography (SPET) to be today performed using the-pinhole collimator with again the advantage of a higher resolution. Pinhole collimator imposes a short distance (a few centimetres) to the target area and a restricted field of view. Over the last ten years, the potential of pinhole SPET has been essentially investigated for the ankle and the hind foot, the detection of thyroid nodules or abnormal parathyroid glands, the exploration of axillary lymph nodes. The technique was usually compared to planar scintigraphy performed with parallel hole or pinhole collimator. Sometimes a comparison to standard (with parallel hole collimator) SPET or to a morphologic imaging technique was also available. All studies highlight the improvement in resolution afforded by the use of the pinhole collimator. In bone scintigraphy, the delineation of the structures was largely superior allowing the visualisation of significant details usually never seen on scintigraphic images. In thyroid scintigraphy, the better resolution allowed to detect more nodules (essentially infra-centimetre nodules), and to reduce the number of equivocal cases. For abnormal parathyroid gland detection, the number of false negative cases decreased, with a concomitant increase of true positive cases; the glands were more sharply delineated on the images. Pinhole SPET with Tc-99m-tetrofosmin was the only scintigraphic method able to successfully reveal the number of involved lymph nodes in patients with breast cancer. In conclusion pinhole single photon appears as a promising new scintigraphic method allowing to explore small areas with a high resolution. [less ▲]

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See detailClinical aspects of alfaxalone use in rabbits. Partial results.
Tutunaru, Alexandru-Cosmin ULg; Sonea, P; Drion, Pierre ULg et al

in BCLAS, ESLAV (Ed.) Proceedings BCLAS, ESLAV & ECLAM Scientific Meeting (2012, October 15)

Alfaxalone, a synthetic neuroactive steroid, has been shown to induce smooth general anesthesia in wild and companion rabbits. The aim of the study was to test the effect of alfaxolone in experimental ... [more ▼]

Alfaxalone, a synthetic neuroactive steroid, has been shown to induce smooth general anesthesia in wild and companion rabbits. The aim of the study was to test the effect of alfaxolone in experimental rabbits without concomitant oxygen supplementation.Respiratory status was assessed by measuring the duration of the post-induction apnea, the respiratory rate, the oxygen saturation of hemoglobin in the peripheral blood (SpO2) and the end-tidal CO2 (EtCO2) Cardiac function was assessed by monitoring heart rate using a pulse oximeter. The degree of anesthesia was monitored by evaluating ear and paw pinch reflex, as well as ocular signs such as nystagmus, exophtalmia and the loss of palpebral and corneal reflexes. [less ▲]

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See detailClinical aspects of bluetongue in ruminants
Guyot, Hugues ULg; Mauroy, Axel ULg; Kirschvink, N. et al

in Bluetongue in northern Europe (2008)

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See detailClinical Assessment of alfaxolone in rabbits
Tutunaru, Alexandru-Cosmin ULg; Sonea, Alexandru; Drion, Pierre ULg et al

Poster (2012, October 19)

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See detailClinical biliary complications after adult liver transplantation: a prospective study
Detry, Olivier ULg; Maweja, Sylvie ULg; Delwaide, Jean ULg et al

in Acta Gastro-Enterologica Belgica (2000, March), 63(1), 56

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See detailA clinical case of congenital tremors in piglets without evidence of PCV-1 and PCV-2
wavreille; Simon, Fanny (Co-first author); Servais, Vincent et al

Poster (2013, May 22)

Congenital tremor (CT) is a disease of newborn pigs characterized by spontaneous clonic contractions of one or more groups of voluntary muscles. Besides suspected or confirmed etiologies of CT such as ... [more ▼]

Congenital tremor (CT) is a disease of newborn pigs characterized by spontaneous clonic contractions of one or more groups of voluntary muscles. Besides suspected or confirmed etiologies of CT such as classical swine fever virus, pseudorabies virus, Japanese encephalomyelitis virus, hereditary disorders in Landrace or Saddleback pigs, organophosphorus poisoning etc., porcine circovirus (PCV) has been described as a potential cause of CT. The type AII seems to be the most common form of CT. Although a potential association between PCV1 or PCV2 and CT-AII has been observed, about 50% CT cases described up till now are caused by unknown reasons. In a PCV-seropositive 108-sow, farrow-to-finish Belgian pig farm breeding hyperprolific Landrace, 42 litters with shaking piglet(s) were reported since June 2006. On March 2012, piglets born from four sows of a 27 sow batch demonstrated CT. After exclusion of main etiologies of CT from these CT-affected piglets, it was hypothesized that PCV1 or PCV2 could be the reason. Necropsies (n=8) and histopathology (n=3) were performed and no evidence of macroscopic or microscopic lesions were seen in cerebrum, cerebellum and spinal cord. Pre-suckled and post-suckled (after 3 days of colostrum uptake) serum samples were also collected from 9 piglets to determine PCV1- and PCV2-specific Ab titres by an immuno-peroxidase monolayer assay (IPMA). No PCV-specific Ab titres were observed in pre-suckled serum samples (≤40), whereas IPMA Ab titres of ≥640 were observed in post-suckled serum samples. Both PCV1 and PCV2 could not be isolated (<101.7 TCID50/g tissue) from 4 tested piglets (in heart, brain and lungs). The present results do not support the hypothesis that PCV1 or PCV2 are linked to CT in newborn piglets. [less ▲]

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See detailClinical Case of the Month. Cerebrovascular Accident Related to Arterial Brachiocephalic Trunk Stenosis
Pirard, Laurence ULg; Belachew, Shibeshih ULg; Trotteur, Geneviève ULg et al

in Revue Médicale de Liège (2006), 61(7-8, Jul-Aug), 553-8

The authors report the case of a 47-year old man, admitted for syncope and left-sided motor deficit. Diagnostic investigations revealed a right middle cerebral artery embolic stroke, secondary to a ... [more ▼]

The authors report the case of a 47-year old man, admitted for syncope and left-sided motor deficit. Diagnostic investigations revealed a right middle cerebral artery embolic stroke, secondary to a critical stenosis of the arterial brachiocephalic trunk, harboring a floating thrombus. The treatment options for occlusive lesions of the brachiocephalic trunk are discussed, as well as the optimal delay between stroke and brain revascularization. [less ▲]

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See detailClinical Cases : use of a low fat diet in hyperlipidaemic dogs
Diez, Marianne ULg; Doneux, B.; Schobyn, P. et al

in Congress Proceedings 10th Congress of the ESVCN (2006)

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See detailClinical cases of anemia
Amory, Hélène ULg

in In proceedings of the II Encontro de Formação da Ordem dos Médicos Veterinários (2011, October 08)

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See detailClinical cases of icterus
Amory, Hélène ULg

in In proceedings of the II Encontro de Formação da Ordem dos Médicos Veterinários (2011, October 08)

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