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See detailChanging of blood culture isolates in a referral neonatal intensive care unit.
Battisti, Oreste ULg; Mitchison, R.; Davies, P. A.

in Archives of Disease in Childhood (1981), 56

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See detailChanging of blood culture isolates in neonates
Battisti, Oreste ULg; Oto, A.; Mitchison, R. et al

in Early Human Development (1980)

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See detailChanging pattern of bacterial susceptibility to antibiotics in hematopoietic stem cell transplant recipients.
Frere, Pascale ULg; Hermanne, J.-P.; Debouge, M.-H. et al

in Bone Marrow Transplantation (2002), 29(7), 589-94

Adequate infection prophylaxis and empirical antibiotic therapy are of critical importance after hematopoietic stem cell transplantation (HSCT). We examined the evolution of bacterial susceptibility to ... [more ▼]

Adequate infection prophylaxis and empirical antibiotic therapy are of critical importance after hematopoietic stem cell transplantation (HSCT). We examined the evolution of bacterial susceptibility to antibiotics in 492 patients (198 allografts and 294 autografts) transplanted between 1982 and 1999 and evaluated whether ciprofloxacin prophylaxis and an empirical antibiotic regimen (glycopeptide + third-generation cephalosporin) were still valid. We collected all susceptibility tests performed during the initial hospitalization on blood cultures as well as routine surveillance cultures and analyzed susceptibility to ciprofloxacin and to major antibiotics used in our unit. Gram-positive cocci rapidly became resistant to ciprofloxacin (susceptibility around 70% in 1990 to less than 20% in 1998) but sensitivity to glycopeptides remained unaltered. There was a rapid decline in the number of patients colonized with Gram-negative bacilli in the early years of ciprofloxacin prophylaxis. However, susceptibility to ciprofloxacin fell sharply from around 90% in 1990 to around 30% in 1999. In parallel, susceptibility to ceftazidime also decreased to less than 80% in recent years. Piperacillin (+/- tazobactam) did not show any variation over time and its efficacy remained too low (about 60%). Imipenem as well as recently introduced cefepim and meropenem showed stable and excellent profiles (>90% susceptibility). In conclusion: (1) quinolone prophylaxis has now lost most of its value; (2) the choice of a third-generation cephalosporin for empirical antibiotic therapy may no longer be the best because of the emergence of Gram-negative strains resistant to beta-lactamases, such as Enterobacter sp. More appropriate regimens of empirical antibiotic therapy in HSCT recipients may be based on the use of a carbapenem or fourth-generation cephalosporin. [less ▲]

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See detailChanging Patterns of Political Participation of Citizens of Immigrant Origin in the Brussels Capital Region. The October 2000 Elections
Martiniello, Marco ULg; Rea, Andrea; Jacobs, Dirk

in Journal of International Migration & Integration (2003), 3(2), 201-221

The October 2000 elections did constitute a landmark for the political participation of immigrant origin citizens in the Brussels Capital Region. There was a remarkable increase of elected Belgian ... [more ▼]

The October 2000 elections did constitute a landmark for the political participation of immigrant origin citizens in the Brussels Capital Region. There was a remarkable increase of elected Belgian politicians of non-EU–mainly Moroccan–origin. In this contribution we want to discuss the changing patterns of political participation of immigrant origin citizens in the Brussels Capital Region as seen in the most recent local elections. We contextualize the electoral success of Turkish and (mainly) Moroccan politicians and the poor involvement of EU citizens in the recent elections. To this purpose, we also discuss the political situation in the bilingual region of Brussels, Belgian citizenship law and regulations for political participation of foreign residents. [less ▲]

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See detailChanging public viewpoints on wind energy development in Belgium
Vanderheyden, Vincent ULg; Schmitz, Serge ULg

in Abstracts. Energy Landscapes: Perception, Planning, Participation and Power. European Conference of the Landscape Research Group, Dresden, 16‐18 September 2015 (2015, September)

The amount of wind turbines has increased exponentially in Belgium in the last eight years (175 in 2007, 771 in 2015). During this period, especially in the last two years, critics of this energy have ... [more ▼]

The amount of wind turbines has increased exponentially in Belgium in the last eight years (175 in 2007, 771 in 2015). During this period, especially in the last two years, critics of this energy have become more organised, virulent, and active in delaying or stopping many projects. The landscape impact of wind energy is central to their arguments. We wonder if people’s attitudes towards wind turbines and landscape changed in the last years in Belgium and how they changed. This paper compares public perception of wind energy in two researches about landscape perception. The two studies used slightly different methodologies but with similarities in the designs, allowing some comparisons. The first research (2007‐2009) aimed to study the perceived landscape impact and the social acceptance of wind turbines in Belgium. 1542 Belgians were surveyed about their landscape preferences using a photo‐questionnaire, including some pictures with wind turbines. 75 stakeholders of wind energy projects were also interviewed. The second research (2012‐2014) aimed to examine deeper the landscape preferences among 54 residents in three areas in Wallonia where wind turbines are present, using the previous photographs. During the conduct of the first research, changing attitudes were already observed. People had become more familiar with wind turbines and were less reluctant. The symbolic positive aspect of wind energy was highlighted seven years ago. This view continues. However, people seem more categorical in their viewpoint. All respondents have now been confronted to wind energy, which was not the case seven years ago. Some persons are not against wind farms but their increase in number start to overwhelm them. Others point they get used to the turbines, as long as they are not too many and too close. The huge increase in wind farms in the last seven years has changed the acceptance of wind energy. Some doubts about the real efficiency of this energy also shaped the attitudes. [less ▲]

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See detailChanging sensitivity to duration in human scalar timing: An experiment, a review, and some possible explanations
Ferrara, André ULg; Lejeune, Helga ULg; Wearden, J. H.

in Quarterly Journal of Experimental Psychology. B, Comparative & Physiological Psychology (1997), 50B

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See detailChanging species diversities in Pennsylvanian tropical wetland communities
Cleal, Christopher J.; King, Sara C.; Cascales - Miñana, Borja ULg et al

Conference (2010, October)

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See detailThe changing spectrum of coma
Laureys, Steven ULg; Boly, Mélanie ULg

in Nature Clinical Practice Neurology (2008), 4(10), 544-546

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See detailThe changing spectrum of TSH-secreting pituitary adenomas: diagnosis and management in 43 patients.
Valdes Socin, Hernan Gonzalo ULg; Chanson, Philippe; Delemer, B. et al

in European Journal of Endocrinology (2003), 148(4), 433-442

OBJECTIVE: Our aim was to report the recent changes in diagnosis and management of TSH-secreting pituitary adenomas. METHODS: We retrieved 43 consecutive patients with TSH-secreting pituitary tumors (23 ... [more ▼]

OBJECTIVE: Our aim was to report the recent changes in diagnosis and management of TSH-secreting pituitary adenomas. METHODS: We retrieved 43 consecutive patients with TSH-secreting pituitary tumors (23 male and 20 female) among 4400 pituitary adenomas followed between 1976 and 2001 in six Belgian and French centers. RESULTS: TSH was elevated in 18/43 and alpha subunit in 13/32 patients. In patients with intact thyroid (n=30), mean free tri-iodothyronine was 13.1 pmol/l (range 3.5-23) and mean free thyroxine was 38.4 pmol/l (range 10.2-62.7). Hyperprolactinemia and acromegaly were associated in 9/43 and 8/43 cases. The number of associated hypersecretions was higher in macroadenomas than in microadenomas (Chi square = 11.2, P<0.01). Two women had sporadic multiple endocrine neoplasia type 1-associated syndrome. The proportion of microadenomas versus macroadenomas was 1/11 (period 1974-1986) and 8/32 (period 1987-2001). Bilateral petrosal sinus sampling, (111)In-pentreotide scintigraphy and ((11)C)-l-methionine positron emission tomography scan confirmed diagnosis in four questionable microadenomas. Macroadenomas with extrasellar extension (31 cases) had a tendency to be medially located. Medical treatment with somatostatin analogs was initiated as first-line treatment in 26 patients. TSH levels were reduced by more than 50% in 23/26 cases. A tumoral shrinkage of more than 20% was observed in 5/13 cases. Surgery was performed in 36 patients. After 1 year, 21 of them (58.3%) met the criteria of surgical favorable outcome. Pituitary radiotherapy (n=8) and somatostatin analogs allowed normalization in cases not cured by surgery. CONCLUSION: Ultrasensitive methods for TSH measurement led to an earlier recognition of TSH-secreting pituitary tumors. In this series, we observed that TSH-secreting pituitary tumors are today more frequently found at the stage of microadenomas, medially located, without associated hypersecretions and needing new exploration methods as compared with older series. This changing spectrum in the presentation of TSH-secreting pituitary tumors and the excellent response to somatostatin analogs has been accompanied by an improvement in the prognosis of the disease. [less ▲]

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See detailCHANGING THE ELECTRONIC DENSITY OF THE DISTAL PHENYL RING OF 4-ARYL-1,2,3,6-TETRAHYDROPYRIDINE DERIVATIVES TO INFLUENCE THE AFFINITY FOR 5-HT1A RECEPTORS
Liégeois, Jean-François ULg; Lespagnard, Marc; Meneses-Salas, Elsa et al

Poster (2013, July)

4-Phenyl-1,2,3,6-tetrahydropyridine(THP) moiety was shown to be favourable compared to the classical 4-phenyl-piperazine in terms of affinity for 5-HT1A receptors in a series of 4-arylpiperazine-ethyl ... [more ▼]

4-Phenyl-1,2,3,6-tetrahydropyridine(THP) moiety was shown to be favourable compared to the classical 4-phenyl-piperazine in terms of affinity for 5-HT1A receptors in a series of 4-arylpiperazine-ethyl carboxamides. The almost planar orientation found in the 4-phenyl-1,2,3,6-THP compounds appeared to be an important spatial requirement for an optimal interaction with the 5-HT1A receptor in this series. This orientation tends to stabilize the ligand binding by an edge-to-face CH-Π interaction between the phenyl ring of the 4-phenyl-1,2,3,6-THP compounds and the side chain of the Phe 6.52 residue in the binding pocket .In the present study, the electronic distribution of the distal benzene ring is modified by introducing substituents with different electronic and/or physicochemical characteristics to explore the impact on this interaction on the affinity for 5-HT1A receptors. These substituents were placed either in 4 or 3 and 5 position of the distal ring in order to avoid a sterical constraint if present in 2 or 6 position. In a quinoxalinamide series, the 3,5-dimethyl substituted analogue has the highest affinity for 5-HT1A receptors as expected. A reinforced interaction with the Phe 6.52 residue might explain this affinity but increased basicity and lipophilicity might also have a role. [less ▲]

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See detailThe changing UV and X-ray properties of the Of?p star CPD -28°2561
Nazé, Yaël ULg; Sundqvist, Jon O.; Fullerton, Alex W. et al

in Monthly Notices of the Royal Astronomical Society (2015), 452

The Of?p star CPD -28°2561 was monitored at high energies with XMM-Newton and HST. In X-rays, this magnetic oblique rotator displays bright and hard emission that varies by ~55 per cent with rotational ... [more ▼]

The Of?p star CPD -28°2561 was monitored at high energies with XMM-Newton and HST. In X-rays, this magnetic oblique rotator displays bright and hard emission that varies by ~55 per cent with rotational phase. These changes occur in phase with optical variations, as expected for magnetically confined winds; there are two maxima and two minima in X-rays during the 73 d rotational period of CPD -28°2561. However, contrary to previously studied cases, no significant hardness variation is detected between minima and maxima, with the exception of the second minimum which is slightly distinct from the first one. In the UV domain, broad-band fluxes remain stable while line profiles display large variations. Stronger absorptions at low velocities are observed when the magnetic equator is seen edge-on, which can be reproduced by a detailed 3D model. However, a difference in absorption at high velocities in the C IV and N V lines is also detected for the two phases where the confined wind is seen nearly pole-on. This suggests the presence of strong asymmetries about the magnetic equator, mostly in the free-flowing wind (rather than in the confined dynamical magnetosphere). [less ▲]

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See detailChannel catfish virus gene 50 encodes a secreted, mucin-like glycoprotein
Vanderheijden, Nathalie; Hanson, Larry A.; Thiry, Etienne ULg et al

in Virology (1999), 257(1), 220-7

Cells infected with the wild-type (WT) strain of channel catfish virus (CCV) secreted a glycoprotein with an apparent molecular mass (MM) superior to 200 kDa into the culture medium. This protein ... [more ▼]

Cells infected with the wild-type (WT) strain of channel catfish virus (CCV) secreted a glycoprotein with an apparent molecular mass (MM) superior to 200 kDa into the culture medium. This protein, designated gp250, was the sole viral glycoprotein detected in the culture medium after [3H]mannose labeling of the infected cells. When cells were infected with the attenuated V60 strain, a glycoprotein of 135 kDa (designated gp135) was detected instead of gp250. Because WT gene 50 is predicted to encode a secreted, mucin-type glycoprotein, we expressed this gene transiently and detected a glycoprotein of the same apparent MM as gp250 in the culture medium of transfected catfish cells. The increased mobility in SDS-PAGE of the secreted V60 glycoprotein correlated with the presence of a major deletion in V60 gene 50. Therefore, we concluded that gp250 in the WT and gp135 in the V60 strains are both likely encoded by gene 50. An important shift in the relative mobility of gp250 in SDS-PAGE was observed after tunicamycin treatment of infected cells labeled with [3H]glucosamine, confirming the presence of N-linked sugars on gp250. We observed variations in the size of PCR products derived from gene 50 amplification in three different field isolates. Such genetic variations are a characteristic feature of mucin genes and are linked to crossing-over events between internal repeated sequences, such as those present in gene 50. [less ▲]

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See detailChannel development in two streams of contrasting bedload and regime
Petit, François ULg

in River Channel Dynamics, International Geomorphology (1986)

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See detailLa Chanson du mal-aimé : un triste et mélodieux délire au seuil de la modernité
Purnelle, Gérald ULg

Article for general public (2011)

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See detailChansons liégeoises de conscrits. La mise en page de la voix populaire
Droixhe, Daniel ULg

in Leclerc, M.-D.; Robert, A. (Eds.) Chansons de colportage (2002)

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See detailLe chant comme support à l’acquisition du langage : Effets de l’expertise musicale ou linguistique
Larrouy, Pauline ULg

Master's dissertation (2009)

Le chant, omniprésent dans notre vie, constitue également un matériel écologique et multidimensionnel qui allie les dimensions musicale et linguistique. Il offre ainsi un outil privilégié pour observer ... [more ▼]

Le chant, omniprésent dans notre vie, constitue également un matériel écologique et multidimensionnel qui allie les dimensions musicale et linguistique. Il offre ainsi un outil privilégié pour observer les relations entre la musique et le langage. Afin d’examiner la spécificité du traitement des informations langagières et musicales dans le chant, nous avons étudié l’influence de l’expertise musicale ou langagière sur l’utilisation des probabilités transitionnelles, un type d’apprentissage statistique implicite particulièrement important dans le développement langagier. Dans le but d’étudier l’intervention de modulations fréquentielles dans l’utilisation des propriétés statistiques des syllabes, Schön, Boyer, Moreno, Besson, Peretz et Kolinsky (2008) avaient mis au point une méthode astucieuse et ont ouvert la voie à l’expérimentation du bénéfice du chant dans l’acquisition du langage. Grâce à leur matériel et à la conception d’une expérience exploratoire, nous avons comparé les performances de sujets non-experts, experts en musique et experts en langage dans l’utilisation des probabilités transitionnelles d’un matériel linguistique et musical. Schön et al (2008) avaient mis en évidence le bénéfice des propriétés structurales et motivationnelles de la musique contenues dans le chant. Nos résultats ne répliquent pas cette étude chez des non-experts mais une interaction significative apparaît entre les expériences proposées et le type d’expertise. Les experts en musique semblent bénéficier des informations musicales et linguistiques pour l’apprentissage statistique lorsqu’elles sont présentées de manière congruente. Par ailleurs, une incongruité entre l’information linguistique et musicale aiderait les experts en langage à utiliser des probabilités transitionnelles de la parole. Les différentes analyses ont guidé notre réflexion sur la spécificité du traitement des paroles et de la mélodie contenues dans le chant. La discussion relative aux effets observés permet d’envisager de futures recherches dans ce domaine et l’exploration de la musicalité de la parole dans une perspective de clinique logopédique. [less ▲]

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See detailLe chant des Belges en 1914-18- l'élan d'une nation
Peere, Isabelle ULg

in B.A.S.I.S Ballads and Songs -- International Studies (2008), B.A.S.I.S 4

La recherche porte sur un corpus inédit de quelque 200 textes de chants populaires 'belges', en langue française et wallonne, provenant de cahiers de chansons ou de feuilles volantes, et se rapportant ... [more ▼]

La recherche porte sur un corpus inédit de quelque 200 textes de chants populaires 'belges', en langue française et wallonne, provenant de cahiers de chansons ou de feuilles volantes, et se rapportant directement à la guerre de 1914-18. [less ▲]

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See detailLe chantier B : résultats de six campagnes de fouilles (1998-2004)
Van der Stede, Véronique ULg

Scientific conference (2005, April 15)

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