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See detailVagus nerve stimulation in awake rats reduces formalin-induced nociceptive behaviour and fos-immunoreactivity in trigeminal nucleus caudalis
Bohotin, C.; Scholsem, M.; Multon, Sylvie ULiege et al

in Pain (2003), 101(1-2), 3-12

Besides its well-established efficacy in epilepsy, vagus nerve stimulation (VNS) may be of potential interest in pain treatment. It has, however, not yet been assessed in animal pain models with the ... [more ▼]

Besides its well-established efficacy in epilepsy, vagus nerve stimulation (VNS) may be of potential interest in pain treatment. It has, however, not yet been assessed in animal pain models with the devices and stimulation protocols used in humans. We have therefore studied in awake rats the effects of left cervical VNS on trigeminal nociception using an implantable electrode and stimulator (NCP-Cyberonics((R)). VNS was applied for 24 h at 2 mA intensity, 20 Hz frequency, 0.5 ms pulse width and a duty cycle of 20 s ON/18 s OFF. As a nociceptive stimulus, we injected formalin into the left mystacial vibrissae, assessed behaviour for 45 min and sacrificed the animals 45 min later. Fos-immunoreactive (Fos-Ir) neurons were counted in laminae I-II of trigeminal nucleus caudalis (TNC on both sides. We used three groups of control animals: VNS without formalin, formalin without VNS and sham VNS (implanted without stimulation or formalin). Whereas sham VNS had no significant effect, VNS alone increased Fos expression in ipsilateral TNC in addition to the expected increase in nucleus tractus solitarius. It also significantly attenuated the increase of Fos-Ir neurons observed in ipsilateral TNC laminae I-II after formalin injection. If the proper VNS effect on Fos-expression was subtracted, the reduction of formalin-induced nociceptor activation was 55%. VNS also reduced nociceptive behaviour on average by 96.1% during the early phase (0-6 min) and by 60.7% during the late phase (6-45 min) after the formalin injection. These results suggest that VNS applied with a device used in human therapy may have in awake rats a significant antinociceptive effect in a model of trigeminal pain. (C) 2002 International Association for the Study of Pain. Published by Elsevier Science B.V. All rights reserved. [less ▲]

Detailed reference viewed: 54 (1 ULiège)
See detailVaincre le mal de dos.
Henrotin, Yves ULiege

Article for general public (2011)

Detailed reference viewed: 28 (4 ULiège)
See detailVaincre le Stapylococcus aureus : antibiothérapie ou vaccination?
Jolois, Olivier ULiege

Scientific conference (2009, January 08)

Detailed reference viewed: 35 (14 ULiège)
See detailLa vaisselle du Piano della Civita / Artena (Italie) : le témoignage du verre
Dienst, Simon ULiege

Scientific conference (2016, October 27)

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See detailVajon depolitizalhato-e a jogdogmatika avagy nem, es ne is remenykedjunk benne?
Paksy, Máté ULiege

in Hegyi, Szabolcs; Vinnai, Edina; Ződi, Zsolt (Eds.) Orbis Iuris. Ünnepi tanulmánykötet Szabó Miklós 65. születésnapjára (2016)

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See detailLe Val-Benoît, témoignage majeur du Modernisme à Liège
Housen, Jean ULiege

in Cahiers de l'Urbanisme (Les) (2009), 73

The Val-Benoît mini-campus, in a dilapidated state due to neglect, is currently under threat. Apart from its undoubtedly aesthetic qualities, most of the buildings also have an exceptional potential for ... [more ▼]

The Val-Benoît mini-campus, in a dilapidated state due to neglect, is currently under threat. Apart from its undoubtedly aesthetic qualities, most of the buildings also have an exceptional potential for redevelopment. Furthermore, their simple and resistant structure has enabled them to survive complete neglect over several years without any major damage. Nowadays, designated as a site for redevelopment by the Walloon Region, Val-Benoît deserves a great deal more than its current fate. Le « mini-campus du Val-Benoît, aujourd’hui fragilisé par l’abandon, est aujourd’hui en danger. Au delà de leurs qualités esthétiques indiscutables, la plupart des bâtiments possèdent aussi un exceptionnel potentiel de réaffectation. En outre, leur structure simple et résistante leur a permis de passer sans trop de dégâts majeurs quelques années d’abandon complet. Aujourd’hui reconnu comme Site à Réaménager par la Région wallonne, le Val-Benoît mérite beaucoup mieux que son sort actuel. [less ▲]

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See detailVal-Dieu et le Trésor de la Cathédrale de Liège, p. 26-31.
George, Philippe ULiege

in Patrimoine de l'abbaye Notre-Dame du Val-Dieu (1992)

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See detailVal-Dieu, abbaye cistercienne des anciens Pays-Bas
Henneau, Marie-Elisabeth ULiege

in Hubert, Jean-Christophe; Eeckhout, Jérôme (Eds.) Notre-Dame du Val-Dieu. Une abbaye, un Ordre, une histoire (1998)

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See detailVALAPODYN: A new systems biology approach to develop predictive dynamic models of complex intracellular networks for neurological disease
Sanoudou, Despina; Depaulis, Antoine; Vafiadaki, Elizabeth et al

Poster (2008, August 22)

Objective: VALAPODYN, a European Commission funded research network, is using an original systems biology approach for the development of an innovative dynamic model of molecular interaction networks (MIN ... [more ▼]

Objective: VALAPODYN, a European Commission funded research network, is using an original systems biology approach for the development of an innovative dynamic model of molecular interaction networks (MIN) in relation to cell death and survival for the detection of new therapeutic targets for human neurological diseases. To this end, a comprehensive multidisciplinary strategy has been established combining functional genomics, proteomics and bioinformatics. Results: Using a mouse model of induced hippocampal sclerosis associated with focal epilepsy, dynamic expression analyses are conducted at different time points. Proteomic databases are being used along with advanced microarray and proteomics platform systems to investigate protein-protein interactions and regulation networks, identify and validate biological targets in complex intracellular pathways. The first phase involves whole genome and proteome analysis, integrating biological and statistical data in order to functionally annotate genes and proteins. Using Affymetrix microarrays, 2D-DIGE and MALDI/TOF-TOF, we are evaluating whole genome and proteome expression profiles bringing to light critical new pathways and molecular targets implicated in neurodegeneration. Conclusion: VALAPODYN develops a dynamic and quantitative analysis method for new therapeutic targets through MIN dynamic models and specifically addresses the systems biology of complex cellular pathways and transcriptional networks. Novel predictive dynamic models will be validated by testing the selected drug targets on innovative in vivo and in vitro models of CNS pathologies. VALAPODYN will provide a cutting-edge highly accurate in silico tool for identifying novel and effective therapeutic targets in a faster, more efficient and more economical way than it is possible today. [less ▲]

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See detailVALAPODYN: VALIDATED PREDICTIVE DYNAMIC MODEL OF COMPLEX INTRACELLULAR PATHWAYS RELATED TO CELL DEATH AND SURVIVAL
Depaulis, Antoine; Vafiadaki, Elizabeth; Jackers, Pascale ULiege et al

Poster (2007, May 17)

VALAPODYN is a research network funded by the European Commission (6th Framework Program) which is developing an original systems biology approach focused on the development of multidisciplinary ... [more ▼]

VALAPODYN is a research network funded by the European Commission (6th Framework Program) which is developing an original systems biology approach focused on the development of multidisciplinary functional genomics related to complex biological processes and cellular networks. The aim is to generate an innovative approach to model the dynamics of molecular interaction networks (MIN) in relation to cell death and survival to detect new therapeutic targets to treat human brain diseases. The project consists of fundamental genomics research which is integrating statistical data analysis with real biological data in order to functionally annotate genes and proteins. Specialized genomics and proteomics databases for MIN modeling are being used along with leading microarray and proteomics platform systems to investigate protein-protein interactions and regulation networks. This will help to identify and validate biological targets in complex intracellular pathways to cure multifactorial diseases. Dynamic modeling specifically addresses the systems biology of complex cellular pathways and transcriptional networks. The novel dynamic models will be validated by testing the selected drug targets on innovative in vivo and in vitro models of CNS pathologies. As opposed to most current biological data analysis methods, VALAPODYN develops a dynamic and quantitative analysis method for new therapeutic targets through MIN dynamic models. It will provide a cutting-edge highly accurate in silico tool for identifying novel and effective therapeutic targets in a much faster, more efficient and more economical way than it is possible today. (www.valapodyn.eu). [less ▲]

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See detailVALAPODYN: Validated Predictive Dynamic Model of Complex Intracellular Pathways Related to Cell Death and Survival
Depaulis, Antoine; Vafiadaki, Elizabeth; Jackers, Pascale ULiege et al

in European Journal of Human Genetics (2007, June 16), 15(Supp 1), 307

VALAPODYN is a research network funded by the European Commission (6th Framework Program) which is developing an original systems biology approach focused on the development of multidisciplinary ... [more ▼]

VALAPODYN is a research network funded by the European Commission (6th Framework Program) which is developing an original systems biology approach focused on the development of multidisciplinary functional genomics related to complex biological processes and cellular networks. The aim is to generate an innovative approach to model the dynamics of molecular interaction networks (MIN) in relation to cell death and survival to detect new therapeutic targets to treat human brain diseases. The project consists of fundamental genomics research which is integrating statistical data analysis with real biological data in order to functionally annotate genes and proteins. Specialized genomics and proteomics databases for MIN modeling are being used along with leading microarray and proteomics platform systems to investigate protein-protein interactions and regulation networks. This will help to identify and validate biological targets in complex intracellular pathways to cure multifactorial diseases. Dynamic modeling specifically addresses the systems biology of complex cellular pathways and transcriptional networks. The novel dynamic models will be validated by testing the selected drug targets on innovative in vivo and in vitro models of CNS pathologies. As opposed to most current biological data analysis methods, VALAPODYN develops a dynamic and quantitative analysis method for new therapeutic targets through MIN dynamic models. It will provide a cutting-edge highly accurate in silico tool for identifying novel and effective therapeutic targets in a much faster, more efficient and more economical way than it is possible today. (www.valapodyn.eu). [less ▲]

Detailed reference viewed: 44 (10 ULiège)
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See detailValdeblore (06) Le Clouté
Pagès, Gaspard ULiege

in Archéologie Médiévale (2010), 40

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See detailValdeblore (06) Le Clouté
Pagès, Gaspard ULiege

in D.R.A.C., S.R.A. (Ed.) Bilan scientifique de la région Provence-Alpes-Côte d’Azur 2010 (2011)

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See detailValdeblore (06) Le Clouté
Pagès, Gaspard ULiege

in D.R.A.C., S.R.A. (Ed.) Bilan scientifique de la région Provence-Alpes-Côte d’Azur 2009 (2010)

Detailed reference viewed: 14 (0 ULiège)
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See detailValdem Project : From building waste LCA to buildings circular economy
Groslambert, Sylvie ULiege; Roy, Aubin

Conference (2017, November 09)

From resource prospective, building and construction sector is responsible for more than third of global resource consumption, including 12% of the fresh water use and its generation of solid waste is ... [more ▼]

From resource prospective, building and construction sector is responsible for more than third of global resource consumption, including 12% of the fresh water use and its generation of solid waste is estimated to be 40% of the total waste volume. At European level, construction and demolition waste is the largest waste stream representing one third of all waste produced in EU. Therefore the resource efficiency and management is crucial in building construction. A very significant part of the Construction and Demolition Waste (CDW) is not recycled today. Also a very limited part is used as a recycled content in the construction and building products and materials. This lack is mainly due to heterogeneity and dispersion of waste flows decreasing efficiency and economic viability of recycling. To address this issue, VALDEM project (funded by Interreg FWVL European Fund) aims to overcome barriers to increase up-cycling applications. The project focuses its activities in North of France, Flanders and Walloon regions (Belgium), and stands out from usual approaches by its cross-border view of circular economy. VALDEM aims, on one hand, to optimize buildings end of life management by developing new deconstruction, sorting and recycling processes to produce uniform and accessible material flows. On the other hand, the project aims at increasing recycling and generating high quality secondary materials (concrete and other flows) to be used in future buildings within an up cycling prospective. And finally it aims at validating the solutions from technical, scientific, economic and environmental point of view. The Environmental assessment, based on LCA, consists of identifying hotspots and key aspects to prioritize the efforts of different economic actors. As a first step, an LCA meta-analysis is conducted to provide an environmental picture for different potential activities within the scope of the project. As a next step, a comparative LCA is conducted to assess the environmental benefits and impacts of different solutions proposed in the framework of the project in a decision making context, and to limit the impact transfer and to generate the maximum value for all the stakeholders. Finally, results will be transferred to main actors (recycling operators, buildings contractors, product manufacturers …) in the three regions in order to consolidate future key aspects to eco-design a building in light of circular economy. [less ▲]

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See detailValence des verbes et interdépendances entre lexique et syntaxe en kirundi
Tuyubahe, Pascal ULiege

Doctoral thesis (2017)

Ce travail de recherche a pour objet de décrire des phénomènes lexicaux et syntaxiques du kirundi peu examinés précédemment. Il est subdivisé en deux principales parties : la première partie est consacrée ... [more ▼]

Ce travail de recherche a pour objet de décrire des phénomènes lexicaux et syntaxiques du kirundi peu examinés précédemment. Il est subdivisé en deux principales parties : la première partie est consacrée à l’élaboration d’un lexique valenciel des verbes avec un ou plusieurs compléments, en prenant comme points de départ la liste de lexèmes de de Samie (2008) ainsi que le dictionnaire rundi-français de Rodegem (1970). Il s’avère que beaucoup de verbes peuvent apparaître dans différents schémas de construction, ce qui implique plusieurs unités lexicales pour ces verbes dans le lexique valenciel. La deuxième partie, composée de sept chapitres, consiste en la recherche de généralisations pouvant être faites à partir de ce lexique ; ces généralisations reposant sur une large base empirique, elles sont assez fréquemment accompagnées d’exceptions. Le chapitre 1 concerne le comportement syntaxique des groupes nominaux et groupes prépositionnels dans la valence des verbes et leur caractérisation par des tests; il y est question des objets directs, des objets prépositionnels, des circonstants et des attributs. Un chapitre est consacré au passif impersonnel (chapitre 2) car cette construction fournit une justification purement empirique à la catégorie « objet prépositionnel » en kirundi, permettant de distinguer les objets prépositionnels (locatif ou non) des autres compléments (y compris les circonstants valenciels de lieu). Le chapitre 3 montre l’importance quantitative des objets directs par rapport aux autres objets du lexique valenciel des verbes en kirundi et montre comment cette importance est encore accrue par l’existence en kirundi d’objets directs non valenciels, en particulier les objets introduits par l’intermédiaire d’un suffixe verbal (suffixe applicatif -ir- ou suffixe causatif -i- ou -iish-) et les possesseurs inaliénables introduits sans intermédiaire. Après avoir fait une présentation générale des temps et aspects et de la concordance des temps en kirundi (chapitre 4), les chapitres 5, 6 et 7 montrent comment cela se manifeste dans les propositions subordonnées valencielles et les propositions avec auxiliaire, en distinguant celles qui ont un verbe conjugué et celles qui ont un infinitif. Les conclusions générales sont suivies des propositions prospectives permettant d’effectuer des recherches approfondies en vue de compléter le lexique valenciel, d’une part et, d’autre part, de déterminer les conditions d’emploi des suffixes causatifs -i- et -iish-. [less ▲]

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See detailThe Valence Quark Distribution of the Pion
Lansberg, Jean-Philippe ULiege; Bissey, F.; Cudell, Jean-René ULiege et al

in Dong Su; Burchat, Patricia (Eds.) XXII Physics in Collision Conference (PIC02) (2002)

Detailed reference viewed: 32 (5 ULiège)
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See detailValence transversities: the collinear extraction
Courtoy, Aurore ULiege; Bacchetta, Alessandro; Radici, Marco

in PoS - Proceedings of Science (2013)

Detailed reference viewed: 9 (1 ULiège)