References of "Brain and Cognition"
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See detailComparison of three learning methods in a patient with early Alzheimer's disease
Bier, N.; Gagnon, L.; Van der Linden, Martial et al

in Brain and Cognition (2004, October), 56(1), 116

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See detailLeft inferior frontal cortex is involved in probabilistic serial reaction time learning
Peigneux, Philippe ULg; Maquet, Pierre ULg; Van der Linden, Martial ULg et al

in Brain and Cognition (1999), 40(1), 215-219

Cerebral blood flow was estimated using positron emission tomography and H2O15 infusions in 12 volunteers while they were trained on the probabilistic serial reaction time task developed by Jimenez ... [more ▼]

Cerebral blood flow was estimated using positron emission tomography and H2O15 infusions in 12 volunteers while they were trained on the probabilistic serial reaction time task developed by Jimenez, Mender, and Cleeremans (1996). Participants' reaction rimes to predictable and nonpredictable stimuli showed increasing sensitivity to the: probabilistic constraints set by previous elements of the sequence. Analysis by statistical parametric mapping showed a significant interaction between participants' performance and time effect in the left inferior frontal cortex. Our results provide the first evidence of this cerebral area being involved in the processing of contextual information in a probabilistic sequence learning task. [less ▲]

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See detailWorking memory deficits in Alzheimer's disease
Collette, Fabienne ULg; Van der Linden, Martial ULg; Bechet, Sophie ULg et al

in Brain and Cognition (1998), 37(1), 147-149

The phonological loop and central executive components of working memory were examined in patients with Alzheimer's disease (AD patients) and elderly controls. Patients with Alzheimer's disease showed ... [more ▼]

The phonological loop and central executive components of working memory were examined in patients with Alzheimer's disease (AD patients) and elderly controls. Patients with Alzheimer's disease showed reduced verbal spans, with smaller phonological similarity and word length effects. They also showed a decreased performance in tasks examining processing speed and articulation rate. However, phonological analysis was normal. With regard to the central executive, AD patients showed deficits in an alphabetical span task in which subjects were asked to recall a random series of words in their alphabetical order, while they performed normally on a dual task in which they had to perform simultaneously a digit repetition and a visuomotor task. These results suggests that Alzheimer's disease may affect several components of working memory but all aspects of the central executive mechanism are not necessarily affected. [less ▲]

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