Growth hormone-binding protein (GHBP) binds prolactine in cattle plasma

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1995), 103

Localization and transmembrane topology of a new member of the mitochondrial carrier family, the yeast RIM 2 gene product

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1995)

Biodegradation of the polycyclic aromatic hydrocarbons phenanthrene, naphtalene and biphenyl by bacteria isolated from a contaminated soil.

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1994), 102(B8),

La fonction centrale du thymus dans la reconnaissance des fonctions neuroendocrines par les lymphocytes T au cours de leur développement

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1993), 101(4, Jul-Aug), 19-22

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular ... [more ▼]

The dual physiological role of the thymus in T cell positive and negative selection appears prominent in the establishment of appropriate host immune defenses. However, the cellular and molecular mechanisms underlying those thymic functions begin only to be understood. On the basis of our previous investigations about the thymic expression of different neuroendocrine-related signals, we have advanced a model which transposes at the peptide level the intervention of this primary lymphoid organ in both T cell positive and negative selective processes. There is now ample evidence that the thymic subcapsular and medullary epithelium is the site for synthesis of neurohypophysial (NHP)-related peptides (reviewed in Geenen et al., 1992a). We have also demonstrated that the epithelial component of thymic "nurse" cells (TNC) synthesizes NHP-related peptides and expresses a neuroendocrine-like phenotype (Geenen et al., 1988a). This observation was a remarkable example of the intimate neuroendocrine-immune interactions that take place during T cell ontogeny. Further immunocytochemical analyses have confirmed that one dominant NHP-related epitope belongs to the oxytocin (OT) lineage of the NHP peptide superfamily (Robert et al., 1991, 1992). The intrathymic coexpression of this OT-like epitope with a neurophysin protein domain is a strong argument for a local synthetic process similar to the hypothalamo-NHP one. However, the absence of ir-OT in secretory granules of thymic epithelial cells (TEC), as well as of NHP-related peptides in the supernatant of TEC cultures questioned the application to the thymus of the classical neurosecretory model established for hypothalamic magnocellular neurons (Scharrer [less ▲]

Modelling the Arterial Wall by Finite Elements

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1993), 101(3, May-Jun), 185-91

The mechanical behaviour of the arterial wall was determined theoretically utilizing some parameters of blood flow measured in vivo. Continuous experimental measurements of pressure and diameter were ... [more ▼]

The mechanical behaviour of the arterial wall was determined theoretically utilizing some parameters of blood flow measured in vivo. Continuous experimental measurements of pressure and diameter were recorded in anesthetized dogs on the thoracic ascending and midabdominal aorta. The pressure was measured by using a catheter, and the diameter firstly, at the same site, by a plethysmograph with mercury gauge and secondly, by a sonomicrometer with ferroelectric ceramic transducers. The unstressed radius and thickness were measured at the end of each experiment in situ. Considering that the viscous component is not important relatively to the nonlinear component of the elasticity and utilizing several equations for Young modulus calculation (thick and thin wall circular cylindrical tube formulas and Bergel's equation) the following values were obtained for this parameter: 0.6 MPa-2 MPa in midabdominal aorta and 2 MPa-6.5 MPa in thoracic ascending aorta. The behaviour of the aorta wall was modelled considering an elastic law and using the finite element program "Lagamine" working in large deformations. The discretized equilibrium equations are non-linear and a unique axi-symmetric, iso-parametric element of 1 cm in length with 8 knots was used for this bi-dimensional problem. The theoretical estimation of radius vessel, utilizing a constant 5 MPa Young modulus and also a variable one, are in good agreement with the experimental results, showing that this finite element model can be applied to study mechanical properties of the arteries in physiological and pathological conditions. [less ▲]

Identification of Three-Element Windkessel Model: Comparison of Time and Frequency Domain Techniques

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100(3, May-Jun), 295-301

The problem of the parameter identification of the three-element windkessel model is studied. Minimization by least-square technique--LSQ--in time domain and frequential techniques--FFT--are compared ... [more ▼]

The problem of the parameter identification of the three-element windkessel model is studied. Minimization by least-square technique--LSQ--in time domain and frequential techniques--FFT--are compared. Continuous pressure and flow curves were recorded in the proximal aorta of an open chest dog. Comparison shows very high correlations between the parameter estimations obtained by LSQ and FFT methods. However, systematic differences appear between the calculated values, but do not seem to endanger physiological interpretation of the results. [less ▲]

Two-dimensional study of varicella-zoster virus proteins

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100(2), 39

HIV-1 reactivation after an oxidative stress

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Varicella-zoster gene 63 encoded protein is an important regulatory factor

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100

Identification of growth-hormone binding proteins (GBBPs) in cattle

in Archives Internationales de Physiologie, de Biochimie et de Biophysique (1992), 100