References of "Revue Médicale de Liège"
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See detailComment je traite ... une obesite severe et ses anomalies metaboliques par une gastroplastie.
Luyckx, Françoise ULg; Scheen, André ULg; Letiexhe, Michel ULg et al

in Revue Médicale de Liège (1999), 54(3), 138-42

Severe obesity, defined as a body mass index > or = 35 kg/m2, is frequently associated with various biological abnormalities, particularly in the presence of intra-abdominal adiposity. The most important ... [more ▼]

Severe obesity, defined as a body mass index > or = 35 kg/m2, is frequently associated with various biological abnormalities, particularly in the presence of intra-abdominal adiposity. The most important disorders belong to the so-called insulin resistance syndrome, metabolic syndrome or syndrome X: hyperinsulinaemia, impaired glucose tolerance or type 2 diabetes, dyslipidaemias, hyperuricaemia, hyperfibrinogenaemia. All these metabolic abnormalities are considered as cardiovascular risk factors. They are also correlated with the severity of the liver steatosis which is commonly observed in individuals with severe obesity. We report our experience of the evolution of these metabolic abnormalities after a marked weight loss induced by gastroplasty. We will analyse the favourable effects of bariatric surgery on insulin sensitivity, biological components of the metabolic syndrome, type 2 diabetes and liver steatosis. [less ▲]

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See detailPharma-clinics le medicament du mois. L'orlistat (xenical).
Scheen, André ULg; Ernest, Philippe ULg; Letiexhe, Michel ULg

in Revue Médicale de Liège (1999), 54(3), 192-6

Orlistat (tetrahydrolipstatin), launched by Roche under the trade name Xenical, is a selective inhibitor of pancreatic and gastro-intestinal lipases. It reduces the digestion of dietary fat and its ... [more ▼]

Orlistat (tetrahydrolipstatin), launched by Roche under the trade name Xenical, is a selective inhibitor of pancreatic and gastro-intestinal lipases. It reduces the digestion of dietary fat and its resorption through digestive mucosa by around 30%. It is indicated, at a dose of 3 x 120 mg/day (one dose with each meal) and together with a moderately low-calorie and low-fat diet, for the treatment of obesity. It has been shown, in placebo-controlled two-year trials, to almost double the number of obese subjects who succeed in loosing at least 10% of initial body weight. Independently, it contributes to decrease serum cholesterol levels by 6-10%. Because of its mechanism of action, this drug can induce intestinal side-effects which tend to decrease with time and with the reduction of fat intake, thus improving diet compliance. [less ▲]

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See detailLe diabete gestationnel: physiopathologie et signification pronostique pour la mere.
Geronooz, I.; Scheen, André ULg; Lefebvre, Pierre ULg

in Revue Médicale de Liège (1999), 54(5), 434-9

Pregnancy is associated with important changes in mother metabolism, especially in late gestation, among which a decreased glucose tolerance caused by insulin resistance. In some of these women, glucose ... [more ▼]

Pregnancy is associated with important changes in mother metabolism, especially in late gestation, among which a decreased glucose tolerance caused by insulin resistance. In some of these women, glucose intolerance is increased by a defect in B-cell function and diabetes mellitus occurs. These women who develop a gestational diabetes need a close follow-up because they are at high risk for further development of diabetes, especially type 2 diabetes. [less ▲]

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See detailComment j'explore ... le risque coronarien individuel extrapole a 10 ans.
Scheen, André ULg; Rorive, Georges ULg; Kulbertus, Henri ULg

in Revue Médicale de Liège (1999), 54(2), 118-21

The European Societies of Cardiology. Atherosclerosis and Hypertension agreed upon a table allowing to evaluate the coronary risk after 10 years according to five parameters (sex, age, smoking, total ... [more ▼]

The European Societies of Cardiology. Atherosclerosis and Hypertension agreed upon a table allowing to evaluate the coronary risk after 10 years according to five parameters (sex, age, smoking, total cholesterol, arterial blood pressure) and aggravating factors (familial history, diabetes mellitus, low HDL cholesterol, hypertriglyceridaemia). The risk level is based upon the equations of the prospective US study of Framingham. The calculation of such a risk is mainly interesting before considering intensified primary prevention in an individual free of any cardiovascular disease. The efforts should first focus on individuals with a high coronary risk, i.e. > 20% after 10 years. As far as secondary prevention is concerned, the patients should always be considered at high risk and beneficiate of all available therapeutic means. [less ▲]

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See detailLe risque cardio-vasculaire lie a l'hypercholesterolemie: d'un continuum a la notion de normalite, de seuil d'intervention et d'objectif therapeutique.
Scheen, André ULg

in Revue Médicale de Liège (1999), 54(1), 17-21

There appears to be a continuum between the cardiovascular risk and the level of blood cholesterol, which hinders the definition of normal values, intervention threshold and therapeutic goals. The more ... [more ▼]

There appears to be a continuum between the cardiovascular risk and the level of blood cholesterol, which hinders the definition of normal values, intervention threshold and therapeutic goals. The more and more convincing evidences provided by the "Evidence-Based Medicine" should be confronted to the pharmaco-economical constraints in order to first focus the essential of the efforts and resources on the target population with the highest risk. Unfortunately, the therapeutic strategy concerns a rather high percentage of the population of industrialized countries. [less ▲]

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See detailTraitement antimigraineux: présent et avenir
Schoenen, Jean ULg

in Revue Médicale de Liège (1999), 54(2), 79-86

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See detailL'abus de prescription des substances soporifiques, stupéfiantes ou psychotropes
Boxho, Philippe ULg

in Revue Médicale de Liège (1999), 54

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See detailPrise en charge médico-chirurgicale des enfants cardiopathes: résultats de l'expérience liégeoise
Massin, M.M.; RADERMECKER, Marc ULg; Jalali, H. et al

in Revue Médicale de Liège (1999), 54(2), 95-9

OBJECTIVE: Evaluation of the results obtained in the management of congenital heart diseases in Liege. MATERIAL AND METHODS: We evaluated the results, the mortality and the morbidity of diagnostic and ... [more ▼]

OBJECTIVE: Evaluation of the results obtained in the management of congenital heart diseases in Liege. MATERIAL AND METHODS: We evaluated the results, the mortality and the morbidity of diagnostic and interventional cardiac catheterization, and of the cardiac surgery in the 123 cardiac children who were referred to us during the three first years of operation of our medico-surgical team. RESULTS: 89 children underwent a catheterization, including 12 therapeutic interventions, whereas 68 were operated. In the two domains, the results are completely comparable with those of the established centers. CONCLUSIONS: The widening of the activity of paediatric cardiology and the creation of an activity of pediatric cardiac surgery in Liege appeared important to us for the quality of management of the cardiac children. This goal could be reached only if our results were comparable with those of the literature. The bet seems to be held. The ultimate objective is to contribute by an adequate policy of management to the quality of life and the health of the cardiac children. [less ▲]

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See detailLa dysplasie fibromusculaire
VAN DAMME, Hendrik ULg; Quaniers, Janine ULg; Limet, Raymond ULg

in Revue Médicale de Liège (1999), 54(12), 935-42

Fibromuscular dysplasia is a rare non-atherosclerotic, non-inflammatory arterial disease. It concerns less than 1% of all occlusive artery lesions, but is more common in young female patients, with a ... [more ▼]

Fibromuscular dysplasia is a rare non-atherosclerotic, non-inflammatory arterial disease. It concerns less than 1% of all occlusive artery lesions, but is more common in young female patients, with a prevalence of 3 to 5% of the arterial lesions in that age group. It mainly attains renal and carotid arteries. The authors discuss the etiopathogeny, the prevalence and treatment of fibromuscular dysplasia. Their own surgical experience with 21 renal and 10 carotid lesions of fibromuscular is exposed. [less ▲]

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See detailActualisation de la prise en charge de l'hypertension artérielle
Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1999), (54), 683-687

The International Society of Hypertension and the World Heath Organisation have recently published new guidelines for the management of hypertension. Epidemiologic studies have shown that management of ... [more ▼]

The International Society of Hypertension and the World Heath Organisation have recently published new guidelines for the management of hypertension. Epidemiologic studies have shown that management of hypertension still remains insatisfactory. The aim of the treatment is to reduce the cardiovascular morbidity and mortality by normalizing blood pressure. The target blood pressure under treatment must be less than 140/90 mmHg, and even lower for diabetic or chronic renal failure patients. In parallel, all cardio-vascular risk factors have to be corrected to decrease the global cardio-vascular risk. [less ▲]

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See detailPharma clinics. Comment je traite ... la sténose d'artère rénale
Krzesinski, Jean-Marie ULg; Turatzinze, Léopold

in Revue Médicale de Liège (1999), 54(9), 719-721

Renal artery stenosis is mainly due to atherosclerosis, but also to fibromuscular dysplasia. Treatment can consist eisther of angioplasty (± stent) or of surgical revascularization. Hypertension induced ... [more ▼]

Renal artery stenosis is mainly due to atherosclerosis, but also to fibromuscular dysplasia. Treatment can consist eisther of angioplasty (± stent) or of surgical revascularization. Hypertension induced by atherosclerotic disease is rarely cured, but more easily controlled. The renal function is often improved and thus this disease must be searched in the presence of renal insufficiency of unknown cause or refractory hypertension. [less ▲]

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See detailPharma clinics. Comment je traite ... les troubles de la calcémie
Janssens, Lise; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1999), 54(10), 782-785

Treatment of both hypercalcemia and hypocalcemia depends on the underlying disorder, the magnitude of the calcium abnormalities and the severity of symptoms. In the case of hypercalcemia, there is a broad ... [more ▼]

Treatment of both hypercalcemia and hypocalcemia depends on the underlying disorder, the magnitude of the calcium abnormalities and the severity of symptoms. In the case of hypercalcemia, there is a broad selection of effective medications, especially the biphosphonates. Treatment of hypocalcemia relies on the calcium intake and often vitamin D supplementation. For both abnormalities, the underlying cause must be treated, if possible, to definitively restore normocalcemia. [less ▲]

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See detailComment j'explore ... un trouble de la kaliémie
Neven, Ingrid; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1999), 54(12), 943-947

Potassium is the most important intracellular cation,playing a role in neuromuscular excitability. Dyskaliema is common. The consequence of this ionic perturbation could be serious related to its ... [more ▼]

Potassium is the most important intracellular cation,playing a role in neuromuscular excitability. Dyskaliema is common. The consequence of this ionic perturbation could be serious related to its magnitude. Thus a quick etiological approach and a medical intervention are needed to rapidly correct this potentially lethal ionic disturbance and prevent its recurrence. [less ▲]

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See detailComment j'explore ... les troubles de la calcémie
Janssens, Lise; Krzesinski, Jean-Marie ULg

in Revue Médicale de Liège (1999), 54(9), 764-769

Mechanisms for calcium homeostasis are complex but their understanding is important before investigating the calcium disorders. Hypercalcaemia is often due to hyperparathyroidism or cancers. The ... [more ▼]

Mechanisms for calcium homeostasis are complex but their understanding is important before investigating the calcium disorders. Hypercalcaemia is often due to hyperparathyroidism or cancers. The diagnostis must thus be rapid and a treatment decided in a global approach. Hypocalcaemia, more frequently noted, is often due to a general disorder with hypoalbuminemia or chronic renal failure. [less ▲]

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See detailComment j'explore ... une suspicion de sténose d'artère rénale
Krzesinski, Jean-Marie ULg; Turatzinze, Léopold

in Revue Médicale de Liège (1999), 54(8), 702-704

Renal artery stenosis can present 2 clinical pictures, sometimes associated and potentially treatable, due mainly to atherosclerosis, but also to fibromuscular dysplasia. The first possible presentation ... [more ▼]

Renal artery stenosis can present 2 clinical pictures, sometimes associated and potentially treatable, due mainly to atherosclerosis, but also to fibromuscular dysplasia. The first possible presentation is renovascular hypertension which represents 1% of unselected hypertensive populations. The second possible presentation is ischemic renal disease, which represent 10% of the new indications for dialysis therapy and has a 50% mortality rate at 3 years. To explore this disease, arteriography, the gold standard, must be reserved for confirmation and treatment. Hypertension induced by the stenosis is best approached by captopril renal MAG 3 scintigraphy. Measurement of the stenosis severity can be performed either by duplex ultrasonography, magnetic resonance angiography or spinal CT angiography according to patients'characteristics, local experience and facilities. This disease must be searched in the presence of renal insufficiency of unknown cause or refractory hypertension. [less ▲]

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See detailL'anorexie mentale, une maladie grave specifique de la femme jeune.
Scheen, André ULg

in Revue Médicale de Liège (1999), 54(4), 255-61

Anorexia nervosa is characterized by a triad comprising anorexia, weight loss, and amenorrhoea. It is typically present in adolescent or young adult women and its prevalence appears to increase in our ... [more ▼]

Anorexia nervosa is characterized by a triad comprising anorexia, weight loss, and amenorrhoea. It is typically present in adolescent or young adult women and its prevalence appears to increase in our society. Eating disorders may lead to cachexia and various severe complications. This disease, which appears to be associated to a particular psychological background, is triggered by conflictual relationships, usually within the family. The anorectic patient should be carefully evaluated, as soon as possible, from a somatic, dietetic and psychological point of view. A specific therapeutic approach should be rapidly proposed in a specialized centre, if possible by a multidisciplinary team. The treatment is most often difficult and of long duration. Prognosis remains uncertain in most cases, especially when appropriate care is delayed. [less ▲]

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See detailLe quiproquo de la consommation medicale de la femme.
Gillet, Pierre ULg; Tellier, V.

in Revue Médicale de Liège (1999), 54(4), 214-23

By analysing three different Belgian databases, we could demonstrate that whereas women subjectively declare a higher number of diseases, a worse functional state and a higher trend to use medical ... [more ▼]

By analysing three different Belgian databases, we could demonstrate that whereas women subjectively declare a higher number of diseases, a worse functional state and a higher trend to use medical resources, they are, from an objective point of view, less frequently hospitalized and cause a lower cost, at certain ages, for the Social Security. [less ▲]

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See detailHypertension arterielle et diabete de type 2.
Scheen, André ULg; Estrella, F.; Weekers, Laurent ULg

in Revue Médicale de Liège (1999), 54(10), 789-95

Diabetes mellitus is frequently associated with arterial hypertension and the combination of both entities markedly increases the vascular risk. In type 2 diabetes, hypertension appears very early ... [more ▼]

Diabetes mellitus is frequently associated with arterial hypertension and the combination of both entities markedly increases the vascular risk. In type 2 diabetes, hypertension appears very early, especially in the presence of obesity, is part of the insulin resistance syndrome, and contributes to high cardiovascular morbidity and mortality rates in this population. Appropriate regulation of blood pressure is crucial in order to reduce not only microangiopathy (nephropathy and retinopathy) but also macroangiopathy (coronary heart disease and stroke) in hypertensive type 2 diabetic patients. Target blood pressure values have been decreased in recent years and should be < 130/85 mmHg, and may be even lower according to recent data. The optimal modalities of pharmacological treatment remain controversial, but obviously several medications are required to reach such objectives in most hypertensive patients with type 2 diabetes. [less ▲]

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See detailLe cas clinique du mois. Diagnostic et traitement du kyste adventitiel de l'artere poplitee.
Zeaiter, R.; SakalihasanN, Natzi ULg; VAN DAMME, Hendrik ULg et al

in Revue Médicale de Liège (1999), 54(6), 514-6

The authors report the case of a 66-year-old patient with unilateral intermittent claudication, in whom no evidence of intravascular occlusive disease was found. Surgical approach revealed an ... [more ▼]

The authors report the case of a 66-year-old patient with unilateral intermittent claudication, in whom no evidence of intravascular occlusive disease was found. Surgical approach revealed an intraparietal cystic adventitial disease of the popliteal artery. An excision of the affected segment and bypass grafting with the internal saphenous vein was done. [less ▲]

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See detailLe cas clinique du mois. Rupture couverte d'un anevrysme infectieux post-typhique de l'aorte abdominale sous-renale.
SCHILS, Fabian ULg; SakalihasanN, Natzi ULg; Sente, J. M. et al

in Revue Médicale de Liège (1999), 54(10), 786-8

Mycotic aneurysms are uncommon but remain one of the most challenging clinical problems for the vascular surgeon. They are associated with high morbidity and mortality, and the clinical signs and symptoms ... [more ▼]

Mycotic aneurysms are uncommon but remain one of the most challenging clinical problems for the vascular surgeon. They are associated with high morbidity and mortality, and the clinical signs and symptoms are non specific. We report here the case of an abdominal aorta mycotic aneurysm due to salmonellosis treated by insertion of an arterial homograft. [less ▲]

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