References of "Journal of Ethnopharmacology"
     in
Bookmark and Share    
Full Text
Peer Reviewed
See detailFrom ethnobotanical uses of Strychnos henningsii to antiinflammatories, analgesics and antispasmodics
Tits, Monique ULg; Damas, Jacques ULg; Quetin-Leclercq, Joëlle et al

in Journal of Ethnopharmacology (1991), 34

Strychnos henningsii GILG is used in African traditional medicine for the treatment of various ailments, including rheumatism, gastrointestinal complaints, malaria and snake bites. Different preliminary ... [more ▼]

Strychnos henningsii GILG is used in African traditional medicine for the treatment of various ailments, including rheumatism, gastrointestinal complaints, malaria and snake bites. Different preliminary pharmacological experiments are described. The results show that some of the reported folk medicinal applications of S. henningsii can be at least partially explained by the presence of retuline-like alkaloids, whose use could lead to new antinociceptive (antiinflammatory and analgesic) and antispasmodic drugs. [less ▲]

Detailed reference viewed: 23 (3 ULg)
Full Text
Peer Reviewed
See detailSouth American Strychnos Species. Ethnobotany (except Curare) and Alkaloid Screening
Quetin-Leclercq, J.; Angenot, Luc ULg; Bisset, N. G.

in Journal of Ethnopharmacology (1990), 28(1), 1-52

The ethnobotanical uses of South American species of Strychnos L. (Loganiaceae) are reviewed, with the exception of their major role in the preparation of curare, which will be dealt with in detail ... [more ▼]

The ethnobotanical uses of South American species of Strychnos L. (Loganiaceae) are reviewed, with the exception of their major role in the preparation of curare, which will be dealt with in detail elsewhere. Medicinal uses are less common than is the case with the African and Asian species of the genus. About 140 samples, mostly of leaves, belonging to 53 species, have been screened for alkaloids. As with species from other parts of the world, the stem bark and root bark tend to be a richer source than leaves. Nor-harman is present in extracts from S. barnhartiana leaves. Pyridino-indolo-quinolizidinone (angustine-type) bases are also found in several species. The occurrence and pharmacology of the (non-curarizing) alkaloids known to be present in South American Strychnos species is reviewed. [less ▲]

Detailed reference viewed: 31 (5 ULg)
Full Text
Peer Reviewed
See detailScreening of cytotoxic activities of Strychnos alkaloids ( methods and results)
Leclercq, Joëlle; Gillet, Marie-Claire ULg; Bassleer, Roger et al

in Journal of Ethnopharmacology (1986), 15

The potential cytotoxic activities of 46 alkaloids isolated from different Strychnos species were tested on different cancer or normal cells cultured in vitro. The authors use a relatively simple ... [more ▼]

The potential cytotoxic activities of 46 alkaloids isolated from different Strychnos species were tested on different cancer or normal cells cultured in vitro. The authors use a relatively simple microtest which gives good reproducibility. Most of the active compounds belong to the usambarane skeleton but other structure-activity relationships are being discussed. [less ▲]

Detailed reference viewed: 35 (17 ULg)
Full Text
Peer Reviewed
See detailAntimitotic activity of strychnopentamine, a bisindolic alkaloid
Tits, Monique ULg; Desaive, Claude ULg; Marnette, J. M. et al

in Journal of Ethnopharmacology (1984), 12

Strychnopentamine has been tested for its cytotoxicity and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine ... [more ▼]

Strychnopentamine has been tested for its cytotoxicity and antitumor activities and compared with two other bisindolic alkaloids that possess an usambarane skeleton. The presence of a N-methylpyrrolidine group increases the antimitotic activity of this type of alkaloids. [less ▲]

Detailed reference viewed: 14 (4 ULg)