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See detailEndometrial thickness in different cut-off points for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding
To, Hong ULg

in Ultrasound in Medicine & Biology (2011, August 26), 37(8S), 118

Purpose: The aim of this study is to find the suitable cutoff point of endometrial thickness (ET) for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding (PMB). Material ... [more ▼]

Purpose: The aim of this study is to find the suitable cutoff point of endometrial thickness (ET) for predicting abnormal endometrium in Vietnamese women with postmenopausal bleeding (PMB). Material & Methods: A prospective study was carried out during 2 years. 308 women, who did not use any hormone therapy, were suffered from PMB. All of them were measured ET by transvaginal sonography before an endometrial biopsy. Dilation and curettage (D&C) was indicated in women with ET ≥ 3 mm to diagnose an abnormal endometrium (hyperplasia atypia or cancer). We compared the sensitivity and false-negative rate at each 1-mm interval cutoff point of ET for detecting these histopathologies. Results: 292 women gave their consent to perform an endometrial biopsy (D&C). Their mean age was 59.4 ± 9.3 years. The median time of amenorrhea was 5 years (range 2-13 years); 12.67% (95%CI 9.10-17.04) of cases were diagnosed an abnormal ET in which the mean of endometrial thickness found was 4.0±1.7 mm (95% CI 3.8-11.8). In comparison to seven cutoff points, the ET at 4 mm showed the highest detection rate of abnormal endometrium in women with PMB (95% of sensitivity for 4% false-negative rate) Conclusion: The ET at 4 mm is the most suitable cutoff point for predicting an abnormal endometrium in Vietnamese women with PMB. [less ▲]

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