Probing Peptide-Membrane Interactions Using Afm

in Surface and Interface Analysis [=SIA] (2008), 40(3-4), 151-156

Atomic force microscopy (AFM) has become a powerful addition to the range of instruments available to probe the organization of lipid monolayers and bilayers. Currently, AFM is the only tool that can ... [more ▼]

Atomic force microscopy (AFM) has become a powerful addition to the range of instruments available to probe the organization of lipid monolayers and bilayers. Currently, AFM is the only tool that can provide nanoscale topographic images of supported lipid membranes under physiological conditions, enabling researchers to resolve their detailed structure and to monitor their interaction with drugs, peptides and proteins. Here, we survey recent data obtained by our research groups that demonstrate the power of the technique for exploring peptide–membrane interactions, with an emphasis on microbial lipopeptides and on tilted peptides. [less ▲]

XPS data analysis via Wavelets and Fourier Transform.

in Surface and Interface Analysis [=SIA] (2004), 36