References of "Nutrition Clinique et Metabolisme"
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See detailOral administration of a Spirulina extract protects old mice against hepatic “ammaging”
Neyrinck, A.; Taminiau, Bernard ULg; Daube, Georges ULg et al

in Nutrition Clinique et Metabolisme (2016), 30(1), 64

Background & aims: Ageing predisposes to hepatic dysfunction and inflammation that can evolve to non-alcoholic fatty liver disease. Spirulina, a cyanobacterium used as a food additive or food supplement ... [more ▼]

Background & aims: Ageing predisposes to hepatic dysfunction and inflammation that can evolve to non-alcoholic fatty liver disease. Spirulina, a cyanobacterium used as a food additive or food supplement, has been shown to impact immune functions and to improve non-alcoholic steatohepatitis in obese mice. The aim of the present study was to test the potential hepatoprotective effects of Spirulina extract supplementation in aged mice and to determine whether these effects can be related to a modulation of the gut microbiota. Methods: Old mice of 24 months were fed a control diet supplemented with or without 5% Spirulina extract (Biores, Liège, Belgium) and were compared to young mice of 3 months during 6 weeks. Results: Combination of pyrosequencing and qPCR analyses of the 16S rRNA gene revealed a decrease in total bacteria and -among specific changes of gut microbiota composition,- an increase in Allobaculum, Blautia, Roseburia, and Lactobacillus populations by Spirulina treatment. Interestingly, parameters related to the innate immunity, especially T Regulatory cells (FoxP3), CD11b-dendritic cells, cytokines (IL6, IFN MCP-1) and antimicrobial peptides (Pla2g2, Reg3) were upregulated in the small intestine of Spirulina-treated mice. Aged mice exhibited inflammation and oxidative stress in the liver tissue as compared to young mice. The supplementation with Spirulina extract reduced several hepatic inflammatory and oxidative stress markers in old mice. Conclusions: Our study shows for the first time that the oral administration of a Spirulina is able to modulate the gut microbiota, to activate immune system in the gut, thereby improving hepatic inflammation in aged mice. Those data allow to envisagesuggest a new therapeutic tools in the management of immune and metabolic alterations in ageing, based on gut microbes-host interactions. [less ▲]

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See detailComparaison entre les dépenses énergétiques mesurées par Deltatrac II ® et celles mesurées par l’E-COVX ® chez des patients agressés : étude prospective observationnelle
FADEUR, Marjorie ULg; MALHERBE, Christian ULg; LEDOUX, Didier ULg et al

in Nutrition Clinique et Metabolisme (2016), 30

The energy intake to provide to critically ill subjects is a complex issue and the indirect calorimetry (IC) is the reference method to determine it. The energy expenditure (EE) measured by IC, with the ... [more ▼]

The energy intake to provide to critically ill subjects is a complex issue and the indirect calorimetry (IC) is the reference method to determine it. The energy expenditure (EE) measured by IC, with the Deltatrac II®, were compared to values measured by a new module coupled to a ventilator: the E-COVX Material and methods. – ICU patients on mechanical ventilation underwent measurements, simultaneously connected during 20 min to the ventilator.VO2 consumption, VCO2 production, respiratory quotient (RQ) and EE were recorded. These measures were made successively at random and during a same period. Statistics’ Student t -tests were realized to compare the results. Bland and Altman graphs were also made. Results. – Forty-four patients (29 males, aged 6 ±15 years, with a BMI 25.9±5.3 kg/m2) were included. For the Deltatrac II® ,VO2was244±69 mL/min, VCO2 189±47 mL/min, RQ 0.79±0.08 and EE 1648 ±457 kcal/day. VO2, VCO2, and EE differed significantly between the two devices despite similar RQ. By our results, the E-COVX® module significantly overestimates the EE. Conclusion. – E-COVX® is a convenient device to measure EE in ICU. However, this new module overestimates EE (234 kcal/day) compared withDeltatrac II®, gold standard method to measure EE. Significant improvements of this news devices seem mandatory before recommending theirclinical use in ICU. [less ▲]

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See detailDigestibilité et fermentation intestinale de deux sources de protéines animales, soumises ou non à un traitement thermique, chez le rat en croissance
POELAERT, Christine ULg; Despret, Xavier; Thewis, André ULg et al

in Nutrition Clinique et Metabolisme (2014, December), 28(Supplement 1), 176-177

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See detailP180: Intérêt de la modulation du microbiote intestinal par les oligosaccharides non digestibles dans le contrôle de la leucémie et de la cachexie cancéreuse
Bindels, L.B.; Neyrinck, A.M.; Salazar, N. et al

in Nutrition Clinique et Metabolisme (2014, December), 28(S1), 162

Il est à présent clairement établi que l’ensemble des bactéries présentes dans l’intestin (le microbiote intestinal) est capable d’influencer l’homéostasie énergétique et immunitaire de son hôte. Nous ... [more ▼]

Il est à présent clairement établi que l’ensemble des bactéries présentes dans l’intestin (le microbiote intestinal) est capable d’influencer l’homéostasie énergétique et immunitaire de son hôte. Nous avons testé l’hypothèse selon laquelle une modulation du microbiote intestinal par des oligosaccharides issus de la pectine (POS) ou de l’inuline (INU) permet d’interférer avec la progression de la leucémie et des désordres métaboliques associés. [less ▲]

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See detailComment gérer la nutrition artificielle chez un patient diabétique ?
PAQUOT, Nicolas ULg; DE FLINES, Jenny ULg; PREISER, Jean-Charles ULg

in Nutrition Clinique et Metabolisme (2014)

Hyperglycaemia in patients receiving enteral or parenteral nutrition is a major problem due to its high prevalence and possible consequences interms of morbidity and mortality. However, the management of ... [more ▼]

Hyperglycaemia in patients receiving enteral or parenteral nutrition is a major problem due to its high prevalence and possible consequences interms of morbidity and mortality. However, the management of diabetes/stress hyperglycaemia during artificial nutrition remains largely unknown,especially in non-critically ill patients. The indications and access routes for artificial nutrition are not different in patients with diabetes/stressdiabetes than in non-diabetics. We do not recommend using enteral formulas designed for patients with diabetes. The glycaemic objective mustbe individualized. We recommend a preprandial blood glucose levels between 100 and 140 mg/dL (5.5 and 7.8 mmol/L) and postprandial levelsbetween 140 and 180 mg/dL (7.8 and 10 mmol/L). A frequent monitoring of capillary glycaemias is mandatory. The best drug treatment for treatinghyperglycaemia/diabetes is insulin and we recommend to adapt the theoretical insulin action to the nutrition infusion regimen. The managementof these patients needs the help of a multidisciplinary experimented staff. [less ▲]

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See detailDiabète et nutrition artificielle : principes de prise en charge
Quilliot, Didier; Malgras, Aurélie; PAQUOT, Nicolas ULg et al

in Nutrition Clinique et Metabolisme (2013), 27(4), 230-235

At home as in the hospital, the diabetic patients are at high risk of malnutrition. In patients with hyperglycemia in artificial nutrition, the primary objective is to to cover their protein needs and ... [more ▼]

At home as in the hospital, the diabetic patients are at high risk of malnutrition. In patients with hyperglycemia in artificial nutrition, the primary objective is to to cover their protein needs and their caloric needs and to optimize accordingly the antidiabetic treatment. Insulin therapy is the treatment of choice. The use of low glycaemic index is probably better, especially for oral supplementation. An equivalent parenteral carbohydrate intake has a hyperglycaemic effect more important than with the oral or enteral way. The management of hyperglycemia in artificial nutrition requires defining glycemic goals, tailored to the patient, to the type and the sequences of artificial nutrition, establishing patterns of insulin therapy and providing accurate adaptation rules. Above the basal requirement, insulin therapy sufficient to meet caloric exposure must be prescribed appropriate in timing with the artificial nutrition. The use of sliding scale as monotherapy is ineffective. This management requires forming the nurse team. The acute phase has passed, the disease stabilized, it is sometimes possible to introduce oral antidiabetic drugs and stop insulin. In this case, we apply the same prescription rules to these drugs as for the patient fed orally. [less ▲]

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See detailObésité et carences préopératoires
DE FLINES, Jenny ULg; BRUWIER, Laurent; DE ROOVER, Arnaud ULg et al

in Nutrition Clinique et Metabolisme (2013), 27(2), 82-86

It is a common belief that nutritional deficiencies are rare in the Western world due to a wide variety of food supply. However, obese people usually consume dense-energy food but of poor nutritional ... [more ▼]

It is a common belief that nutritional deficiencies are rare in the Western world due to a wide variety of food supply. However, obese people usually consume dense-energy food but of poor nutritional value that lacks proteins, vitamins, minerals and fiber; consequently, a high prevalence of micronutrient deficiencies in obese subjects has been reported. Moreover, bariatric surgery has been proven the most effective treatment of morbid obesity, but micronutrient deficiency following bariatric surgery is a major concern, worsening pre-operative nutritional deficiencies. In this article, we reviewed the litterature and highlighted the prevalence of nutritional deficiencies in the morbidly obese population prior to bariatric surgery, clinical consequences of these deficiencies and practical recommendations for these subjects. [less ▲]

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See detailEvaluation d'un protocole de prise en charge nutritionnelle interdisciplinaire chez des patients brulés
MALHERBE, Christian ULg; VERBRUGGE, Anne-Marie ULg; MAGNETTE, André ULg et al

in Nutrition Clinique et Metabolisme (2012, December), 26-Supp1

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See detailGestion de l'hyperglycémie au cours de la nutrition parentérale
DE FLINES, Jenny ULg; PAQUOT, Nicolas ULg; PREISER, Jean-Charles ULg

in Nutrition Clinique et Metabolisme (2012), 26(3), 143-147

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See detailLes régimes d’épargne protéique dans le traitement de l’obésité
PAQUOT, Nicolas ULg

in Nutrition Clinique et Metabolisme (2001), 15

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