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See detailDescribing the ‘elusive’ : Availability, Preparation and Use of Anthocyanin Colourants in Mediaeval European Illuminators’ Workshops
Neven, Sylvie ULg; Sanyova, Jana

in Dubois, Hélène; Eyb-Green, Sigrid; Kroustallis, Stephanos (Eds.) et al Making and transforming art : changes in artists’ materials and practice (in press)

Anthocyanins are colorants which provide most of the blue, red and violet colours in numerous plants and fruits. Because of their great sensitivity to the slightest changes in pH and their instability in ... [more ▼]

Anthocyanins are colorants which provide most of the blue, red and violet colours in numerous plants and fruits. Because of their great sensitivity to the slightest changes in pH and their instability in ordinary daylight, it is generally thought that these colorants were used only to dye everyday clothes in a domestic context. However, medieval artists’ recipe books not only describe these elusive substances, but also indicate their use in illumination. This is notably the case for the texts of the so-called ‘Strasbourg Tradition’, written in the south of Germany and the north of France between 1400 and 1560, and partly composed from an older Alsatian treatise on illumination. Departing from these sources, this paper details the methods employed to prepare these colorants and (re)evaluates their diverse uses in painting and illuminating techniques. This technical data subsequently served as a basis upon which to make reconstructions. Finally, an attempt to correlate the information provided by these recipe books with specific artistic practices was carried out by collating the descriptions with the results of analyses from contemporary illuminations by an Alsatian workshop active in the same geographical area. [less ▲]

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See detailBrazil – EU Partnership: from high expectations to limited results
Santander, Sébastian ULg; Saraiva, Miriam

in European Journal of International Relations (in press)

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See detailMeteorological variation in daily travel behaviour: evidence from revealed preference data from the Netherlands
Creemers, Lieve; Wets, Geert; Cools, Mario ULg

in Theoretical & Applied Climatology (in press)

This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation ... [more ▼]

This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation (trip motives) and daily modal choices in the Netherlands. To this end, data from the Dutch National Travel Household Survey of 2008 were matched to hourly weather data provided by the Royal Dutch Meteorological Institute and were complemented with thermal indices to indicate the level of thermal comfort and additional variables to indicate the seasonality of the weather conditions. Two multinomial logit–generalised estimation equations (MNL-GEE) models were constructed, one to assess the impact of weather conditions on trip motives and one to assess the effect of weather conditions on modal choice. The modelling results indicate that, depending on the travel attribute of concern, other factors might play a role. Nonetheless, the thermal component, as well as the aesthetical component and the physical component of weather play a significant role. Moreover, the parameter estimates indicate significant differences in the impact of weather conditions when different time scales are considered (e.g. daily versus hourly based). The fact that snow does not play any role at all was unexpected. This finding can be explained by the relatively low occurrence of this weather type in the study area. It is important to consider the effects of weather in travel demand modelling frameworks because this will help to achieve higher accuracy and more realistic traffic forecasts. These will in turn allow policy makers to make better long-term and short-term decisions to achieve various political goals, such as progress towards a sustainable transportation system. Further research in this respect should emphasise the role of weather conditions and activityscheduling attributes. [less ▲]

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See detailVascular calcification: from pathophysiology to biomarkers
EVRARD, Séverine ULg; DELANAYE, Pierre ULg; Kamel, S et al

in Clinica Chimica Acta (in press)

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have ... [more ▼]

The link between vascular calcification (VC) and increased mortality is now well established. Over time, as clinical importance of this phenomenon has begun to be fully considered, scientists have highlightedmore and more physiopathological mechanisms and signaling pathways that underlie VC. Several conditions such as diabetes, dyslipidemia and renal diseases are undoubtedly identified as predisposing factors. But even if the process is better understood,many questions still remain unanswered. This reviewbriefly develops the various theories that attempt to explain mineralization genesis. Nonetheless, the main purpose of the article is to provide a profile of the various existing biomarkers of VC. Indeed, in the past years, a lot of inhibitors and promoters, which form a dense and interconnected network, were identified. Given importance to assess and control mineralization process, a focusing on accumulated knowledge of each marker seemed to be necessary. Therefore, we tried to define their respective role in the physiopathology and how they can contribute to calcification risk assessment. Among these, Klotho/fibroblast growth factor-23, fetuin-A, Matrix Gla protein, Bone morphogenetic protein-2, osteoprotegerin, osteopontin, osteonectin, osteocalcin, pyrophosphate and sclerostin are specifically discussed. [less ▲]

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See detailLes jugements de Dominique Lampson sur Jan Gossart et Lambert Lombard
Allart, Dominique ULg

in Delfosse, Annick; Glesener, Thomas (Eds.) Ecrire, lire et éduquer à la Renaissance, Hommage en l’honneur de Franz Bierlaire (in press)

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See detailSophistique et Philosophie: Platon, héritier de Protagoras
Gavray, Marc-Antoine ULg

Book published by Vrin (in press)

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See detailAmour tordu de la patrie. Érotique et politique dans Pompes funèbres de Jean Genet
Denis, Benoît ULg

in Dubois, Jacques (Ed.) Érotique et politique dans la prose française du XXe-XXIe siècle (in press)

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See detailDramatic osteonecrosis of the jaw associated with oral bisphosphonates, periodontitis and dental implant removal
Ayora, A F; HERION, Francine ULg; ROMPEN, Eric ULg et al

in Journal of Clinical Periodontology (in press)

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these ... [more ▼]

Osteoporosis affects millions of elderly patients, and anti-resorptive drugs (ARD) such as bisphosphonates (BP) represent the first-line therapy. Despite the benefits related to the use of these medications, osteonecrosis of the jaw is a significant complication in a subset of patients receiving these drugs. CASE PRESENTATION: This report documents a case of dramatic bisphosphonate-related osteonecrosis associated with periodontitis and dental implant removal in an osteoporotic patient treated with per os bisphosphonates for an uninterrupted period of 15 years. CONCLUSION: The aim of this report was to discuss the administration period of BP in the treatment of osteoporosis, the decision-making and clinical management of severe MRONJ and the indications for dental implant placement in these specific patients. [less ▲]

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See detailDocument Kinetic study of volatile oil of Curcuma longa L. rhizome and Carum carvi L. fruits extracted by microwave-assisted techniques using the cryogrinding
Akloul, R; Benkaci-Ali, F; Eppe, Gauthier ULg

in Journal of Essential Oil Research (in press)

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the ... [more ▼]

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the cryogrinding (CG) showed differences in yields and composition of volatile oils compared with classical grinding. HDAM–CG (CL: 1.20%, CC: 1.25%) and SDAM–CG (CL: 1.45%, CC: 1.75%) allowed extraction of substantial amounts of volatile oils in less time compared with HDAM (CL: 0.6%, CC: 1.00%) and SDAM (CL: 0.90%, CC: 1.00%). In addition, the major amounts of volatile oils were globally obtained during the first 5 and 10 minutes of extraction for CL and CC, respectively. A kinetic study of essential oils extraction from CL and CC was quantitatively performed. The composition of the major components and family classes present a significant variation with the extraction time. Essential oils extracted by these two methods were quantitatively (yield) and qualitatively [aromatic profile by gas chromatography (GC) and GC–mass spectrometry (GC–MS)] analyzed. There were differences, especially in the major compounds ar-turmerone (HDAM: 46.00–57.96%, HDAM–CG: 30.85–60.32%) and β-turmerone (HDAM: 14.43–16.74%, HDAM–CG: 10.46–15.77%) for CL, and limonene (HDAM: 23.61–56.97%, HDAM–CG: 38.04–43.00%) and carvone (HDAM: 36.19–64.54%, CC–CG: 53.65–56.31%) for CC. [less ▲]

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See detailHis cognitis vs. His cognitis rebus : ordre des constituants et bornage de l’Ablatif absolu
Longrée, Dominique ULg; Philippart de Foy, Caroline ULg; Purnelle, Gérald ULg

in Haverling, Gerd (Ed.) Proceedings of the 16th Int. Coll. on Latin Linguistics, Uppsala, 6-12 juin 2011 (in press)

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See detailPortrait dévotionnel et ascension spirituelle dans la peinture flamande du XVe siècle : le cas de la Vierge d’Exeter de Petrus Christus
Falque, Ingrid ULg

in BERGMANS, Luc (Ed.) La contempplation dans la peinture flamande (14e-16e siècles). Actes de la journée d'études organisée au Centre d'études supérieures de Tours (in press)

Consacré à la célèbre Vierge d’Exeter de Petrus Christus (Berlin, Gemäldegalerie), cet article vise à montrer que le tableau – commandé par le chartreux Jan Vos qui y apparaît en prière devant la Vierge – ... [more ▼]

Consacré à la célèbre Vierge d’Exeter de Petrus Christus (Berlin, Gemäldegalerie), cet article vise à montrer que le tableau – commandé par le chartreux Jan Vos qui y apparaît en prière devant la Vierge – comporte des références au thème de l’ascension spirituelle et visualise ainsi le progrès spirituel de Jan Vos. Ce dernier est représenté à l’entrée du palais céleste, où il est introduit par sa sainte patronne et accueilli par la Vierge. Il s’apprête ainsi à délaisser le monde terrestre, symbolisé par la ville représentée en contrebas, pour rejoindre le Christ et atteindre la béatitude éternelle, comme le préconise Gérard Zerbolt van Zutphen dans son De spiritualibus ascensionibus. Les données historiques relatives au dévot m’ont permis de découvrir qu’il a eu accès à plusieurs ouvrages traitant de l’évolution de la vie intérieure et plus précisément au texte de Zerbolt pendant son séjour long de plusieurs années à la chartreuse de Nieuwlicht. Le lien entre le tableau et le traité de Gérard Zerbolt est ainsi patent. [less ▲]

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See detailDevelopment and validation of the French version of a tool assessing patient's expectations in lower limb osteoarthritis
NEUPREZ, Audrey ULg; Delcour, JP; Fatemi, F et al

in Journal of Orthopaedics (in press)

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See detaileffects of cholecaciferol supplementation and optimized calcium intakes on vitamin D status, muscle strength and bone haelth: a one-year pilot randomized controlled trial in adults with severe burns
ROUSSEAU, Anne-Françoise ULg; FOIDART-DESSALLE, Marguerite ULg; LEDOUX, Didier ULg et al

in Burns : Journal of the International Society for Burn Injuries (in press)

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess ... [more ▼]

Objective: Burn patients are at risk of hypovitaminosis D and osteopenia or sarcopenia. Vitamin D pleiotropic effects may influence bone and muscle health. The aim of this pilot study was to assess effects of a cholecalciferol (VD3) supplementation and an optimized calcium (Ca) regimen on vitamin D (VD) status, bone and muscle health during sequelar stage of burn injury. Design: Monocentric randomized controlled trial. Methods: Fifteen adults with thermal burns dating from 2 to 5 years were randomized into two groups. For 12 months, they either received a quarterly IM injection of 200,000 IU VD3 and daily oral Ca (Group D) or placebo (Group P). VD status and bone remodeling markers were assessed every 3 months. Knee muscle strength and bone mineral density were, respectively, assessed using isokinetic dynamometry and dual X-ray absorptiometry at initiation (M0) and completion (M12) of the protocol. Results: Of all the patients, 66% presented with VD deficiency and 53% (with 3 men <40 y) were considered osteopenic at inclusion. After one year, calcidiol levels significantly increased in Group D to reach 40 (37–61) ng/ml. No significant change in bone health was observed in both groups while Group D significantly improved quadriceps strength when tested at high velocity. Conclusions: This VD3 supplementation was safe and efficient to correct hypovitaminosis D in burn adults. When combined with optimized Ca intakes, it demonstrated positive effects on muscle health but not on bone health. A high prevalence of hypovitaminosis D and osteopenia in these patients, as well as their wide range of muscle performances, seem to be worrying when considering rehabilitation and quality of life. [less ▲]

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See detailAn atomistic view of DNA dynamics and its interaction with small binders: insights from Molecular Dynamics and Principal Component Analysis
Fresch, Barbara ULg; Remacle, Françoise ULg

in Joachim, Christian (Ed.) Advances in Atom and Single Molecule Machines (in press)

DNA oligomers are promising building blocks for the development of bottom-up nano-devices and molecular logic machines. To control and exploit their unique capabilities of self-assembling and molecular ... [more ▼]

DNA oligomers are promising building blocks for the development of bottom-up nano-devices and molecular logic machines. To control and exploit their unique capabilities of self-assembling and molecular recognition a deep understanding of their dynamical properties is essential. We theoretically investigate the dynamics of a DNA dodecamer and its complexes with two common ligands, Hoechst33258 and the ethidium cation, by means of classical Molecular Dynamics (MD) simulations and Principal Component Analysis (PCA). We study the structural relation between the flexibility of the double helix and the binding process. The dynamics of a terminal base pair unbinding is also analysed as an example of process that involves multiple energy minima in the underlying free energy landscape. [less ▲]

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See detailLa bataille de (la) Ptérie. La Lydie face à la Perse (ca. 547 av. J.-C.)
Leloux, Kevin ULg

in Actes du 9e Congrès de l'Association des Cercles Francophones d'Histoire et d'Archéologie de Belgique (23-26 août 2012) (in press)

Chacun sait que chez les anciens Grecs, Crésus passait pour un roi richissime à la tête d’un des plus puissants royaumes de son temps. En apportaient la preuve ses nombreuses offrandes consacrées au ... [more ▼]

Chacun sait que chez les anciens Grecs, Crésus passait pour un roi richissime à la tête d’un des plus puissants royaumes de son temps. En apportaient la preuve ses nombreuses offrandes consacrées au sanctuaire de Delphes, visibles de tous. L’épisode de sa mort sur un bûcher, un des moments les plus dramatiques de son existence, fut évoqué par nombre d’auteurs anciens et elle a fait l’objet de représentations figurées tout au long de l’Antiquité. Enfin, il ne faut pas oublier que pour un Grec du VIe siècle, l’homme passait pour constituer comme un rempart infranchissable protégeant les cités grecques de la côte d’Asie Mineure contre la puissance montante des Perses de Cyrus II le Grand. Ainsi la défaite inattendue du roi lydien face aux troupes perses en Ptérie constitue-t-elle un épisode décisif de l’époque archaïque grecque dans la mesure où elle signe la fin prochaine du royaume lydien et de son formidable maître. Les cités grecques d’Asie Mineure allaient vite devoir face à leur destin : une soumission aux Perses puis leur révolte entraînant les terribles guerres médiques. Dans notre exposé, on mettra l’accent sur les causes de cette bataille décisive perdue par Crésus à Ptérie, sur son déroulement et ses enjeux à la lumière des sources à notre disposition. On sera amené à analyser le tracé de la Route royale empruntée par le dernier descendant de Gygès pour se rendre en Cappadoce ; on aura ainsi l’occasion de voir que son existence est bien antérieure à l’arrivée des Perses en Anatolie occidentale. Enfin notre exposé présentera la localisation exacte de la ville de Ptérie, une question débattue depuis longtemps mais que des fouilles archéologiques récentes ont permis d’éclairer. [less ▲]

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See detailLes maisons de Jeanne Susplugas
Bawin, Julie ULg

in Jeanne Susplugas (monographie) (in press)

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