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See detailA European survey on attitudes towards pain and end-of-life issues in locked-in syndrome
Demertzi, Athina ULg; Jox, Ralf J; Racine, Eric et al

in Brain Injury (in press)

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in ... [more ▼]

Objectives: Patients with locked-in syndrome often self-report a higher quality of life than generally expected. This study reports third-person attitudes towards several salient issues on locked-in syndrome. Methods: Close-ended survey among conference attendees from 33 European countries. Analysis included chi-square tests and logistic regressions. Results: From the 3332 respondents (33% physicians, 18% other clinicians, 49% other professions; 47% religious), 90% agreed that patients with locked-in syndrome can feel pain. The majority (75%) disagreed with treatment withdrawal, but 56% did not wish to be kept alive if they imagined themselves in this condition (p50.001). Religious and southern Europeans opposed to treatment withdrawal more often than non-religious (p50.001) and participants from the North (p¼0.001). When the locked-in syndrome was compared to disorders of consciousness, more respondents endorsed that being in a chronic locked-in syndrome was worse than being in a vegetative state or minimally conscious state for patients (59%) than they thought for families (40%, p50.001). Conclusions: Personal characteristics mediate opinions about locked-in syndrome. The dissociation between personal preferences and general opinions underlie the difference in perspective in disability. Ethical responses to dilemmas involving patients with locked-in syndrome should consider the diverging ethical attitudes of stakeholders. [less ▲]

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See detailOrganic Rankine Cycles including fluid selection
Lemort, Vincent ULg; Declaye, Sébastien ULg; Quoilin, Sylvain ULg

in Handbook of Clean Energy Systems (in press)

An Organic Rankine Cycle (ORC) is similar to a steam Rankine cycle, except that the working fluid is not water but an organic compound, such as a refrigerant or a hydrocarbon, characterized by a lower ... [more ▼]

An Organic Rankine Cycle (ORC) is similar to a steam Rankine cycle, except that the working fluid is not water but an organic compound, such as a refrigerant or a hydrocarbon, characterized by a lower ebullition temperature than that of water. Hence lower temperature heat sources can be exploited such as solar energy, geothermal energy and waste heat recovery from many different processes. During the design phase of an ORC system, the selection of the working fluid must be conducted in parallel with the selection and the sizing of the components (mainly the expansion machine, the pump and the heat exchangers) and with the definition of the cycle architecture. This approach allows taking into consideration all technical constraints. Relevant properties of working fluids that should be considered during their selection are listed. Major characteristics of available displacement and turbo-expander technologies are described. The impact of the pump performance on the overall performance is discussed and strategies to increase the available NPSH are proposed. Finally, improved cycle architectures are introduced. Major applications of ORC systems are described: geothermal power plants, biomass CHP plants, waste heat recovery in industry, waste heat recovery on internal combustion engines and solar power plants. All these applications differ by the nature of the heat source and heat sink, the integration of the ORC with these sources and sinks, and the range of installed capacities. These differences yield specific designs, which are described. Performance achieved by systems in operation or prototypes are presented. [less ▲]

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See detailEnjeux politiques et critiques d'une philosophie des normes
Caeymaex, Florence ULg; Pieron, Julien ULg

in Dissensus (in press), 6(printemps 2014),

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See detailSpazio scritto e spazio non scritto nelle dossografie mediche su papiro
Ricciardetto, Antonio ULg

in Spazio scritto e spazio non scritto nel libro papiraceo: esperienze a confronto (in press)

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See detailPractical management of Chronic Myeloid Leukemia in Belgium
Benghiat, FS.; Beguin, Yves ULg; Dessars, B. et al

in Belgian Journal of Hematology (in press)

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation ... [more ▼]

Imatinib has drastically changed the outcome of patients with chronic myeloid leukemia (CML), with the majority of them showing a normal life span. Recently, the development of second and third generation tyrosine kinase inhibitors (TKIs) and the possibility of treatment discontinuation made the management of these patients more challenging. In this review, practical management guidelines of CML are presented, adapted to the Belgian situation in 2014. In first line chronic phase patients, imatinib, nilotinib and dasatinib can be prescribed. While second generation TKIs give faster and deeper responses, their impact on long-term survival remain to be determined. The choice of the TKI depends on CML risk score, priority for a deep response to allow a treatment-free remission protocol, age, presence of comorbid conditions, side effect profile, drug interactions, compliance concerns and price. Monitoring the response has to be made according the 2013 ELN criteria, and is based on the bone-marrow cytogenetic response during the first months and on the blood molecular response. Molecular follow-up is sufficient in patients with a complete cytogenetic response. For patients who fail frontline therapy, nilotinib, dasatinib, bosutinib and ponatinib are an option depending of the type of intolerance or resistance. T315I patients are only sensitive to ponatinib, which has to be carefully handled due to cardiovascular toxicity. Advanced phase diseases are more difficult to handle, with treatments including allogeneic stem cell transplantation, which is also an option for patients failing at least two TKIs. The possibility of treatment-free remission and pregnancy are also discussed. [less ▲]

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See detailLe cas clinique du mois. Hémangiome épithélioïde, une tumeur osseuse rare.
Gérard, Valérie; TOMASELLA, Marco ULg; KURTH, William ULg et al

in Revue Médicale de Liège (in press)

A case of pathological hip fracture associated with an epithelioid hemangioma is reported. Epithelioid hemangioma is a benign tumor, rarely localized in a bone. When the tumor is found on the skeleton, it ... [more ▼]

A case of pathological hip fracture associated with an epithelioid hemangioma is reported. Epithelioid hemangioma is a benign tumor, rarely localized in a bone. When the tumor is found on the skeleton, it generally involves a long bone. X-ray does not permit the differenciation of epithelioid hemangioma from other,malignant, vascular tumors. Therefore,the diagnosis requires surgery. Although no consensus treatment guidelines exist, the curettage – filling is most often proposed. [less ▲]

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See detailImpacts of climate change on future flood damage on the river Meuse, with a distributed uncertainty analysis
Detrembleur, Sylvain; Stilmant, Frédéric ULg; Dewals, Benjamin ULg et al

in Natural Hazards (in press)

Flood-risk assessments are an objective and quantitative basis for implementing harmonized flood mitigation policies at the basin scale. However, the generated results are subject to different sources of ... [more ▼]

Flood-risk assessments are an objective and quantitative basis for implementing harmonized flood mitigation policies at the basin scale. However, the generated results are subject to different sources of uncertainty arising from underlying assumptions, data availability and the random nature of the phenomenon. These sources of uncertainty are likely to bias conclusions because they are irregularly distributed in space. Therefore, this paper addresses the question of the influence of local features on the expected annual damage in different municipalities. Based on results generated in the frame of a transnational flood-risk-assessment project for the river Meuse (Western Europe) taking climate change into account, the paper presents an analysis of the relative contributions of different sources of uncertainty within one single administrative region (the Walloon region in Belgium, i.e. a river reach of approximately 150 km). The main sources of uncertainty are not only found to vary both from one municipality to the other and in time, but also to induce opposite effects on the computed damage. Nevertheless, practical conclusions for policy-makers can still be drawn. [less ▲]

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See detailDescribing the ‘elusive’ : Availability, Preparation and Use of Anthocyanin Colourants in Mediaeval European Illuminators’ Workshops
Neven, Sylvie ULg; Sanyova, Jana

in Dubois, Hélène; Eyb-Green, Sigrid; Kroustallis, Stephanos (Eds.) et al Making and transforming art : changes in artists’ materials and practice (in press)

Anthocyanins are colorants which provide most of the blue, red and violet colours in numerous plants and fruits. Because of their great sensitivity to the slightest changes in pH and their instability in ... [more ▼]

Anthocyanins are colorants which provide most of the blue, red and violet colours in numerous plants and fruits. Because of their great sensitivity to the slightest changes in pH and their instability in ordinary daylight, it is generally thought that these colorants were used only to dye everyday clothes in a domestic context. However, medieval artists’ recipe books not only describe these elusive substances, but also indicate their use in illumination. This is notably the case for the texts of the so-called ‘Strasbourg Tradition’, written in the south of Germany and the north of France between 1400 and 1560, and partly composed from an older Alsatian treatise on illumination. Departing from these sources, this paper details the methods employed to prepare these colorants and (re)evaluates their diverse uses in painting and illuminating techniques. This technical data subsequently served as a basis upon which to make reconstructions. Finally, an attempt to correlate the information provided by these recipe books with specific artistic practices was carried out by collating the descriptions with the results of analyses from contemporary illuminations by an Alsatian workshop active in the same geographical area. [less ▲]

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See detailBrazil – EU Partnership: from high expectations to limited results
Santander, Sébastian ULg; Saraiva, Miriam

in European Journal of International Relations (in press)

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See detailMeteorological variation in daily travel behaviour: evidence from revealed preference data from the Netherlands
Creemers, Lieve; Wets, Geert; Cools, Mario ULg

in Theoretical & Applied Climatology (in press)

This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation ... [more ▼]

This study investigates the meteorological variation in revealed preference travel data. The main objective of this study is to investigate the impact of weather conditions on daily activity participation (trip motives) and daily modal choices in the Netherlands. To this end, data from the Dutch National Travel Household Survey of 2008 were matched to hourly weather data provided by the Royal Dutch Meteorological Institute and were complemented with thermal indices to indicate the level of thermal comfort and additional variables to indicate the seasonality of the weather conditions. Two multinomial logit–generalised estimation equations (MNL-GEE) models were constructed, one to assess the impact of weather conditions on trip motives and one to assess the effect of weather conditions on modal choice. The modelling results indicate that, depending on the travel attribute of concern, other factors might play a role. Nonetheless, the thermal component, as well as the aesthetical component and the physical component of weather play a significant role. Moreover, the parameter estimates indicate significant differences in the impact of weather conditions when different time scales are considered (e.g. daily versus hourly based). The fact that snow does not play any role at all was unexpected. This finding can be explained by the relatively low occurrence of this weather type in the study area. It is important to consider the effects of weather in travel demand modelling frameworks because this will help to achieve higher accuracy and more realistic traffic forecasts. These will in turn allow policy makers to make better long-term and short-term decisions to achieve various political goals, such as progress towards a sustainable transportation system. Further research in this respect should emphasise the role of weather conditions and activityscheduling attributes. [less ▲]

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See detailLes jugements de Dominique Lampson sur Jan Gossart et Lambert Lombard
Allart, Dominique ULg

in Delfosse, Annick; Glesener, Thomas (Eds.) Ecrire, lire et éduquer à la Renaissance, Hommage en l’honneur de Franz Bierlaire (in press)

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See detailSophistique et Philosophie: Platon, héritier de Protagoras
Gavray, Marc-Antoine ULg

Book published by Vrin (in press)

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See detailCionodendron and related lithostrotionid genera from the Mississippian of eastern Australia: systematics, stratigraphy and evolution
Denayer, Julien ULg; Webb, Gregory E.

in Alcheringa : An Australasian Journal of Paleontology (in press)

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See detailAmour tordu de la patrie. Érotique et politique dans Pompes funèbres de Jean Genet
Denis, Benoît ULg

in Dubois, Jacques (Ed.) Érotique et politique dans la prose française du XXe-XXIe siècle (in press)

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See detailDocument Kinetic study of volatile oil of Curcuma longa L. rhizome and Carum carvi L. fruits extracted by microwave-assisted techniques using the cryogrinding
Akloul, R; Benkaci-Ali, F; Eppe, Gauthier ULg

in Journal of Essential Oil Research (in press)

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the ... [more ▼]

Hydrodistillation assisted by microwave (HDAM) and steam distillation assisted by microwave (SDAM) of Curcuma longa L. rhizome (CL) and Carum carvi fruits (CC) were investigated. The effect of the cryogrinding (CG) showed differences in yields and composition of volatile oils compared with classical grinding. HDAM–CG (CL: 1.20%, CC: 1.25%) and SDAM–CG (CL: 1.45%, CC: 1.75%) allowed extraction of substantial amounts of volatile oils in less time compared with HDAM (CL: 0.6%, CC: 1.00%) and SDAM (CL: 0.90%, CC: 1.00%). In addition, the major amounts of volatile oils were globally obtained during the first 5 and 10 minutes of extraction for CL and CC, respectively. A kinetic study of essential oils extraction from CL and CC was quantitatively performed. The composition of the major components and family classes present a significant variation with the extraction time. Essential oils extracted by these two methods were quantitatively (yield) and qualitatively [aromatic profile by gas chromatography (GC) and GC–mass spectrometry (GC–MS)] analyzed. There were differences, especially in the major compounds ar-turmerone (HDAM: 46.00–57.96%, HDAM–CG: 30.85–60.32%) and β-turmerone (HDAM: 14.43–16.74%, HDAM–CG: 10.46–15.77%) for CL, and limonene (HDAM: 23.61–56.97%, HDAM–CG: 38.04–43.00%) and carvone (HDAM: 36.19–64.54%, CC–CG: 53.65–56.31%) for CC. [less ▲]

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See detailHis cognitis vs. His cognitis rebus : ordre des constituants et bornage de l’Ablatif absolu
Longrée, Dominique ULg; Philippart de Foy, Caroline ULg; Purnelle, Gérald ULg

in Haverling, Gerd (Ed.) Proceedings of the 16th Int. Coll. on Latin Linguistics, Uppsala, 6-12 juin 2011 (in press)

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See detailPortrait dévotionnel et ascension spirituelle dans la peinture flamande du XVe siècle : le cas de la Vierge d’Exeter de Petrus Christus
Falque, Ingrid ULg

in BERGMANS, Luc (Ed.) La contempplation dans la peinture flamande (14e-16e siècles). Actes de la journée d'études organisée au Centre d'études supérieures de Tours (in press)

Consacré à la célèbre Vierge d’Exeter de Petrus Christus (Berlin, Gemäldegalerie), cet article vise à montrer que le tableau – commandé par le chartreux Jan Vos qui y apparaît en prière devant la Vierge – ... [more ▼]

Consacré à la célèbre Vierge d’Exeter de Petrus Christus (Berlin, Gemäldegalerie), cet article vise à montrer que le tableau – commandé par le chartreux Jan Vos qui y apparaît en prière devant la Vierge – comporte des références au thème de l’ascension spirituelle et visualise ainsi le progrès spirituel de Jan Vos. Ce dernier est représenté à l’entrée du palais céleste, où il est introduit par sa sainte patronne et accueilli par la Vierge. Il s’apprête ainsi à délaisser le monde terrestre, symbolisé par la ville représentée en contrebas, pour rejoindre le Christ et atteindre la béatitude éternelle, comme le préconise Gérard Zerbolt van Zutphen dans son De spiritualibus ascensionibus. Les données historiques relatives au dévot m’ont permis de découvrir qu’il a eu accès à plusieurs ouvrages traitant de l’évolution de la vie intérieure et plus précisément au texte de Zerbolt pendant son séjour long de plusieurs années à la chartreuse de Nieuwlicht. Le lien entre le tableau et le traité de Gérard Zerbolt est ainsi patent. [less ▲]

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