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See detailRobust transformation procedure for the production of transgenic farmer-preferred cassava landraces.
Zainuddin, Ima M.; Schlegel, Kim; Gruissem, Wilhelm et al

in Plant methods (2012), 8(1), 24

Recent progress in cassava transformation has allowed the robust production of transgenic cassava even under suboptimal plant tissue culture conditions. The transformation protocol has so far been used ... [more ▼]

Recent progress in cassava transformation has allowed the robust production of transgenic cassava even under suboptimal plant tissue culture conditions. The transformation protocol has so far been used mostly for the cassava model cultivar 60444 because of its good regeneration capacity of embryogenic tissues. However, for deployment and adoption of transgenic cassava in the field it is important to develop robust transformation methods for farmer- and industry-preferred landraces and cultivars. Because dynamics of multiplication and regeneration of embryogenic tissues differ between cassava genotypes, it was necessary to adapt the efficient cv. 60444 transformation protocol to genotypes that are more recalcitrant to transformation. Here we demonstrate that an improved cassava transformation protocol for cv. 60444 could be successfully modified for production of transgenic farmer-preferred cassava landraces. The modified transformation method reports on procedures for optimization and is likely transferable to other cassava genotypes reportedly recalcitrant to transformation provided production of high quality FEC. Because the three farmer-preferred cassava landraces selected in this study have been identified as resistant or tolerant to cassava mosaic disease (CMD), the adapted protocol will be essential to mobilize improved traits into cassava genotypes suitable for regions where CMD limits production. [less ▲]

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See detailFP6 PROHITECH project: Volume 1: Intervention strategies for the seismic protection of historical building heritage in the Mediterranean basin
Aleksievska, Jasmina Hadzieva; Altay Askar, Gülay; Arion, Cristian et al

Book published by Polimetrica (2012)

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See detailSirtuin inhibition attenuates the production of inflammatory cytokines in lipopolysaccharide-stimulated macrophages.
Fernandes, Claudia A.; Fievez, Laurence ULg; Neyrinck, Audrey M. et al

in Biochemical and Biophysical Research Communications (2012), 420(4), 857-861

In several inflammatory conditions such as rheumatoid arthritis or sepsis, the regulatory mechanisms of inflammation are inefficient and the excessive inflammatory response leads to damage to the host ... [more ▼]

In several inflammatory conditions such as rheumatoid arthritis or sepsis, the regulatory mechanisms of inflammation are inefficient and the excessive inflammatory response leads to damage to the host. Sirtuins are class III histone deacetylases that modulate the activity of several transcription factors that are implicated in immune responses. In this study, we evaluated the impact of sirtuin inhibition on the activation of lipopolysaccharide (LPS)-stimulated J774 macrophages by assessing the production of inflammatory cytokines. The pharmacologic inhibition of sirtuins decreased the production of tumour necrosis factor-alpha (TNF-alpha) interleukin 6 (IL-6) and Rantes. The reduction of cytokine production was associated with decreased nuclear factor kappa B (NF-kappaB) activity and inhibitor kappa B alpha (IkappaBalpha) phosphorylation while no impact was observed on the phosphorylation status of p38 mitogen-activated kinase (p38 MAPK). This work shows that sirtuin pharmacologic inhibitors are a promising tool for the treatment of inflammatory conditions. [less ▲]

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See detailIndustrial Policy and Competition Enforcement: Is There, Could There and Should There Be a Nexus?
Petit, Nicolas ULg; Neyrinck, Norman ULg

Conference (2012)

This paper muses on whether there can be, there is, and there should exist a nexus between European Union (“EU”) competition law and industrial policy. A well-known, long lasting grievance in the history ... [more ▼]

This paper muses on whether there can be, there is, and there should exist a nexus between European Union (“EU”) competition law and industrial policy. A well-known, long lasting grievance in the history of EU competition law is indeed that the European Commission (“the Commission”) has allegedly enforced the competition rules dogmatically, and turned a blind eye on industrial policy considerations. Lately, this policy debate has revived. With the current economic debacle in the Western world, decades of free-market economic policies – including competition policies – inherited from the so-called “Washington consensus” are called into question. In contrast, thriving economic models like Brazil, China, or India where the State interferes with the market at the expense of free competition, are increasingly looked by the “old world” as a possible source of inspiration. Those new developments justify devoting another paper to the question whether industrial policy considerations could and should inform EU competition enforcement. To address it, we follow a four steps methodology. We first solve definitional issues by describing the various possible meanings of “industrial policy” (I). Second, we follow a legalistic approach to review whether such considerations can, as a matter of positive law, play a role (II). Third, we turn to empirical analysis, to examine if there has been some industrial policy influence in the Commission’s case-law (III). Fourth, we review consequentialist arguments to assess whether industrial policy considerations should play a stronger role in EU competition enforcement (IV). [less ▲]

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See detailAntiproliferative effect of the arboreal and medicinal species Luehea divaricata on the Allium cepa cell cycle
Frescura, VDS; Laughinghouse IV, Haywood ULg; Tedesco, SB

in Caryologia : Giornale di Citologia, Citosistematica, e Citogenetica (2012), 65(1), 27-33

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See detailWater stress drastically reduces root growth and inulin yield in Cichorium intybus (var. sativum) independently of photosynthesis
Vandoorne, Bertrand; Mathieu, Anne-Sophie; Van den Ende, Wim et al

in Journal of Experimental Botany (2012), 63(12), 4359-4373

Root chicory (Cichorium intybus var. sativum) is a cash crop cultivated for inulin production in Western Europe. This plant could be exposed to severe water stress during the three last months of their ... [more ▼]

Root chicory (Cichorium intybus var. sativum) is a cash crop cultivated for inulin production in Western Europe. This plant could be exposed to severe water stress during the three last months of their six months growing period. The aim of this study was to quantify the effect of a progressive decline in water availability on plant growth, photosynthesis and sugar metabolism and to determine its impact on inulin production. Water stress drastically decreased root fresh and dry weight, leaf number, total leaf area and stomatal conductance. Stressed plants, however, increased their water use efficiency, decreased the shoot to root ratio and lowered their osmotic potential through soluble sugar accumulation. Despite a decrease in photosynthetic pigments, the light phase of the photosynthesis remained unaffected under water stress. Water stress increased sucrose phosphate synthase (SPS) activity in the leaves, but not in the roots. Water stress inhibited sucrose:sucrose 1-fructosyltransferase (1-SST) and fructan:fructan 1 fructosyltransferase (1—FFT) after 19 weeks of culture and slightly increased fructan 1-exohydrolase activities (1-FEH). The root inulin concentration and the mean degree of polymerisation (DP) of the inulin chain remained however unaffected by water stress. It is concluded that root chicory displayed resistance to water stress, but that such a resistance is obtained at the expense of growth which, in turn, leads to significant decrease in inulin production. [less ▲]

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See detailRevue des revues
Paul, Stéphanie ULg

in Kernos : Revue Internationale et Pluridisciplinaire de Religion Grecque (2012), 25

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See detailAspects formels de la poésie de Rose-Marie François
Purnelle, Gérald ULg

in Pagnoulle, Christine (Ed.) Rose-Marie François : des mots et des langues (2012)

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See detailFamilial Pituitary Adenomas
Auriemma, RS; Vasilev, V; Daly, Adrian ULg et al

in Endocrinologia Clinica (2012)

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See detailChapter 17: Thiamin (E-book)
Bettendorff, Lucien ULg

in Erdman, Jr, John W.; MacDonald, Ian A.; Zeisel, Steven H. (Eds.) Present Knowledge in Nutrition (E-book) (2012)

Thiamin (vitamin B1) was the first vitamin characterized and its discovery was at the origin of the concept of vitamin. Thiamin deficiency mainly affects the nervous system and causes two classical ... [more ▼]

Thiamin (vitamin B1) was the first vitamin characterized and its discovery was at the origin of the concept of vitamin. Thiamin deficiency mainly affects the nervous system and causes two classical diseases, beriberi (a polyneuritic syndrome) and Wernicke-Korsakoff syndrome (anterograde amnesia resulting from brain lesions in alcoholics). Thiamin transport through the membranes of intestinal and other cells requires specific carriers. As the process is rather slow, various lipid-soluble thiamin precursors with better bioavailability have been developed. In the cytosol, thiamin is pyrophosphorylated to thiamin diphosphate (ThDP), an indispenable cofactor in cell energy metabolism. Therefore, thiamin deficiency causes decreased cofactor function, leading to neuronal death. In addition, non-cofactor roles of the triphosphorylated derivatives thiamin triphosphate (ThTP) and adenosine thiamin triphosphate (AThTP) may play a role in metabolic regulation and may contribute to the pathology of thiamin deficiency-induced brain lesions. Current research interests are focused on the metabolism and role of thiamin derivatives (especially in catalysis by ThDP-dependent enzymes) and the biochemical and pathophysiological mechanisms by which thiamin deficiency induces specific brain lesions and may be implicated in other disorders such as Alzheimer’s disease and diabetes. [less ▲]

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See detailAdiabatic Solar-Like Oscillations in Red Giant Stars
Montalban Iglesias, Josefa ULg; Miglio, Andrea; Noels-Grötsch, Arlette ULg et al

in Red Giants as Probes of the Structure and Evolution of the Milky Way (2012)

Since the detection of non-radial solar-like oscillation modes in red giants with the CoRoT satellite, the interest in the asteroseismic properties of red giants and the link with their global properties ... [more ▼]

Since the detection of non-radial solar-like oscillation modes in red giants with the CoRoT satellite, the interest in the asteroseismic properties of red giants and the link with their global properties and internal structure is substantially increasing. Moreover, more and more precise data are being collected with the space-based telescopes CoRoT and Kepler. In this paper we present a survey of the most relevant theoretical and observational results obtained up to now concerning the potential of solar-like oscillations in red giants. [less ▲]

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See detailTensile membrane action in composite floors subjected to fire
Franssen, Jean-Marc ULg

in Liew, J Y Richard (Ed.) Advances in steel concrete composite and hybrid structures (2012)

The essential features of composite steel concrete beams and slabs are first given for a load bearing mode in one-way bending. The essential features of the two ways acting tensile membrane action load ... [more ▼]

The essential features of composite steel concrete beams and slabs are first given for a load bearing mode in one-way bending. The essential features of the two ways acting tensile membrane action load bearing mode are then explained. Experimental tests that helped understanding and quantifying the tensile membrane action, either small scale or large scale, at room temperature or in fire condition, are summarized. Simple calculation models that have been developed for calculating the load bearing capacity of composite floor under fire are presented. Considerations are given about the requirements for numerical models aiming at simulating the behavior of composite floor systems in the fire situation are given. Finally, an application example is presented of a composite floor system designed by the author in 2007. [less ▲]

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See detailErrors in 2-D modelling using a 0th order turbulence closure for compound channel flows
Linde, F.; Paquier, A.; Proust, S. et al

in International Conference on Fluvial Hydraulics, River Flow 2012 (2012)

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows ... [more ▼]

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows, comparing the simulations with experiments. Three flow configurations are analyzed: uniform, gradually varied and rapidly varied flows. The last configuration is obtained by setting a transverse embankment on the flood plain. Errors are estimated on the sub-section mean velocity, discharge andwater depth, on the mixing layer width and on the depth-averaged stream-wise velocity and lateral shear stress. Depending on the flow configuration and on the studied parameter, relative errors significantly vary from nearly zero to 50%. The influence of the 0th order turbulence closure on the mean flow and the dimensions of the recirculation zone behind the embankment is also investigated, using either constant eddy viscosity or Elder's model. © 2012 Taylor & Francis Group, London. [less ▲]

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See detailMagnetocaloric and transport study of poly- and nanocrystalline composite manganites La0.7Ca0.3MnO3/La0.8Sr0.2MnO3
Pekala, M; Pekala, K; Drozd, V et al

in Journal of Applied Physics (2012), 112

Magnetocaloric and transport properties are reported for novel poly- and nanocrystalline double composite manganites, La0.8Sr0.2MnO3/La0.7Ca0.3MnO3, prepared by the sol-gel method. Magnetic field ... [more ▼]

Magnetocaloric and transport properties are reported for novel poly- and nanocrystalline double composite manganites, La0.8Sr0.2MnO3/La0.7Ca0.3MnO3, prepared by the sol-gel method. Magnetic field dependence of magnetic entropy change is found to be stronger for the nano- than the polycrystalline composite. The remarkable broadening of the temperature interval, where the magnetocaloric effect occurs in poly- and nanocrystalline composites, causes the relative cooling power (RCP(S)) of the nanocrystalline composite to be reduced by only 10% compared to the Sr based polycrystalline phase. The RCP(S) of the polycrystalline composite becomes remarkably enhanced. The low temperature magnetoresistance is enhanced by 5% for the nanostructured composite. © 2012 American Institute of Physics [less ▲]

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See detailPhénoménologie et objectivisme sémantique dans les Recherches logiques de Husserl
Seron, Denis ULg

in Leclercq, Bruno; Collette-Ducic, Bernard (Eds.) L'Idée de l’idée: Éléments de l'histoire d’un concept (2012)

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See detailConséquences d'une annexion injuste: L'enrôlement de force dans la Wehrmacht et les réfractaires dans les "dix communes". Une mise en perspective
Brüll, Christoph ULg

in Simons, Marc (Ed.) Plombières dans la tourmente (2012)

L’enrôlement dans l’armée allemande est très certainement la conséquence la plus dramatique de l’annexion des « Dix Communes » à l’Allemagne entre 1940 et 1944. S’il revêt une certaine logique du point de ... [more ▼]

L’enrôlement dans l’armée allemande est très certainement la conséquence la plus dramatique de l’annexion des « Dix Communes » à l’Allemagne entre 1940 et 1944. S’il revêt une certaine logique du point de vue des autorités allemandes, il constitue un choc pour une population qui ne peut accepter que de « bons Belges » soient contraints de porter l’uniforme allemand et y voient une profonde injustice. La contribution sera articulée autour des mécanismes de recrutement que les Allemands mettent en place (en 1942-1943) en vue de l’enrôlement après avoir conféré aux habitants des « Dix Communes » le statut de Deutsche auf Widerruf par le décret sur l’octroi de la nationalité allemande du 23 septembre 1941. Les habitants n’auront finalement que deux possibilités : risquer leur vie en fuyant leurs villages ou en se cachant – ce sont ceux qu’on appellera les réfractaires – ou se résigner – ici les raisons peuvent varier de l’obéissance volontaire à la contrainte. Toutefois, dans les travaux scientifiques, la dimension (auto-) biographique, celle des expériences vécues de ces jeunes hommes – qu’ils soient réfractaires ou enrôlés – et de leurs familles, est encore trop peu développée. Dans ce sens, la contribution constituera également un appel à la mémoire locale afin d’ouvrir un débat sur ce passé – serein et affranchi des tensions et des passions de l’après-guerre. [less ▲]

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See detailInterprétation chronostratigraphique de la séquence holocène du Trou Al'Wesse à la lumière des nouvelles datations : du Mésolithique ancien au Néolithique moyen
Miller, Rebecca ULg; Stassart, Edith ULg; Otte, Marcel ULg et al

in Notae Praehistoricae (2012), 32

The AMS dates obtained for the Holocene sequence are stratigraphically coherent, and indicate occupations at Trou Al’Wesse during the Early, Late and Final Mesolithic phases and the during the Middle ... [more ▼]

The AMS dates obtained for the Holocene sequence are stratigraphically coherent, and indicate occupations at Trou Al’Wesse during the Early, Late and Final Mesolithic phases and the during the Middle Neolithic. This paper presents an interpretation of the chronostratigraphy in light of the recently obtained dates. [less ▲]

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See detailRadicalismes et extrémismes de droite
Jamin, Jérôme ULg

in Bouhon, Frédéric; Reuchamps, Min (Eds.) Les systèmes électoraux de la Belgique (2012)

Depuis 1830, la Belgique a connu de nombreuses évolutions en matière électorale. Le XIXe siècle et le début du XXe sont notamment marqués par l’ouverture progressive de la participation de la population ... [more ▼]

Depuis 1830, la Belgique a connu de nombreuses évolutions en matière électorale. Le XIXe siècle et le début du XXe sont notamment marqués par l’ouverture progressive de la participation de la population aux opérations électorales et par leur rationalisation. Au cours des dernières décennies, le système électoral de la Belgique a laissé place à de multiples systèmes électoraux, dans le sillage de la fédéralisation du pays et de la construction européenne. Ainsi, à côté des organes provinciaux et communaux, on ne dénombre pas moins de sept assemblées dont les membres sont directement élus. Même si un certain nombre de règles sont communes à ces différentes institutions, il convient de considérer l’existence d’autant de systèmes électoraux distincts. À ce jour, aucune étude interdisciplinaire n’a fait systématiquement le point sur les systèmes électoraux de la Belgique. Cet ouvrage ambitionne de combler ce vide en réunissant de nombreux spécialistes du droit et de la science politique, mais également de la sociologie, de l’histoire et de la géographie. Une trentaine d’auteurs livrent leurs réflexions sur un thème qui gît au coeur de la vie démocratique d’un pays en pleine mutation. [less ▲]

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