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See detailMT1-MMP protects breast carcinoma cells against type I collagen-induced apoptosis
Maquoi, Erik ULiege; Assent, Delphine; Detilleux, Julien et al

in Oncogene (2012), 31(4), 480-93

As invading breast carcinoma cells breach their underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen. To develop metastatic ... [more ▼]

As invading breast carcinoma cells breach their underlying basement membrane, they become confronted with a dense three-dimensional reactive stroma dominated by type I collagen. To develop metastatic capabilities, invading tumor cells must acquire the capacity to negotiate this novel microenvironment. Collagen influences the fate of epithelial cells by inducing apoptosis. However, the mechanisms used by invading tumor cells to evade collagen-induced apoptosis remain to be defined. We demonstrate that membrane type-1 matrix metalloproteinase (MT1-MMP/MMP-14) confers breast cancer cells with the ability to escape apoptosis when embedded in a collagen gel and after orthotopic implantation in vivo. In the absence of MMP-14-dependent proteolysis, type I collagen triggers apoptosis by inducing the expression of the pro-apoptotic Bcl-2-interacting killer in luminal-like breast cancer cells. These findings reveal a new mechanism whereby MMP-14 activity promotes tumor progression by circumventing apoptosis. [less ▲]

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See detail"La maîtrise du français des étudiants qui accèdent à l'enseignement supérieur"
Defays, Jean-Marc ULiege

Scientific conference (2012, January 26)

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See detailLa ville à l'heure des contraintes énergétiques
Reiter, Sigrid ULiege

Conference (2012, January 26)

Detailed reference viewed: 12 (1 ULiège)
See detailEtude de la qualité de vie et de ses prédicteurs chez les enfants atteints de mucoviscidose
Toucheque, Malorie ULiege

Diverse speeche and writing (2012)

Detailed reference viewed: 24 (4 ULiège)
See detailUn nouveau gouvernement, une première réforme fiscale : point en janvier 2012
Richelle, Isabelle ULiege

Conference (2012, January 26)

Organisation d’un Colloque sur « Un nouveau gouvernement, une première réforme fiscale : le point en janvier 2012 », Académie Royale de Belgique, Bruxelles, 26 janvier 2012, organisation du Tax Institute ... [more ▼]

Organisation d’un Colloque sur « Un nouveau gouvernement, une première réforme fiscale : le point en janvier 2012 », Académie Royale de Belgique, Bruxelles, 26 janvier 2012, organisation du Tax Institute de l’ULg. Direction de la Table ronde. [less ▲]

Detailed reference viewed: 28 (11 ULiège)
See detailTraductor frente a ilustrador
Willson, Patricia ULiege

Article for general public (2012)

Detailed reference viewed: 37 (7 ULiège)
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See detailFeeding Cyprinus carpio with infectious materials mediates cyprinid herpesvirus 3 entry through infection of pharyngeal periodontal mucosa
Fournier, Guillaume ULiege; Boutier, Maxime ULiege; Victor, Stalin Raj et al

in Veterinary Research (2012), 43(6),

Cyprinid herpesvirus 3 (CyHV-3), also known as Koi herpesvirus, is the etiological agent of a mortal disease in common and koi carp. Recently, we investigated the entry of CyHV-3 in carp using ... [more ▼]

Cyprinid herpesvirus 3 (CyHV-3), also known as Koi herpesvirus, is the etiological agent of a mortal disease in common and koi carp. Recently, we investigated the entry of CyHV-3 in carp using bioluminescence imaging and a CyHV-3 recombinant strain expressing luciferase (LUC). We demonstrated that the skin is the major portal of entry after inoculation of carp by immersion in water containing CyHV-3. While this model of infection mimics some natural conditions in which infection takes place, other epidemiological conditions could favour entry of virus through the digestive tract. Here, we investigated whether ingestion of infectious materials mediates CyHV-3 entry through the digestive tract. Carp were fed with materials contaminated with the CyHV-3 LUC recombinant (oral contamination) or immersed in water containing the virus (contamination by immersion). Bioluminescence imaging analyses performed at different times post-infection led to the following observations: (i) the pharyngeal periodontal mucosa is the major portal of entry after oral contamination, while the skin is the major portal of entry after contamination by immersion. (ii) Both modes of inoculation led to the spreading of the infection to the various organs tested. However, the timing and the sequence in which some of the organs turned positive were different between the two modes of inoculation. Finally, we compared the disease induced by the two inoculation modes. They led to comparable clinical signs and mortality rate. The results of the present study suggest that, based on epidemiological conditions, CyHV-3 can enter carp either by skin or periodontal pharyngeal mucosal infection. [less ▲]

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See detailTotal Electron Content reconstruction using triple frequency GNSS signals
Spits, Justine ULiege

Doctoral thesis (2012)

Nowadays, Global Navigation Satellite System (GNSS) provide accurate three dimensional positioning and navigation anywhere and anytime on the Earth’s surface and are being utilized in numerous civilian ... [more ▼]

Nowadays, Global Navigation Satellite System (GNSS) provide accurate three dimensional positioning and navigation anywhere and anytime on the Earth’s surface and are being utilized in numerous civilian and military applications. The US Global Positioning System (GPS) is currently being modernized to transmit radio signals on an additional third frequency, while the European Galileo is a newly developed system which will transmit on three civil frequency bands. One of the major error sources affecting GNSS is the delay caused when the signals pass through the ionosphere on their way to the Earth’s surface. This delay is inversely proportional to the square of the carrier frequency, and directly proportional to the Total Electron Content (TEC) of the ionosphere. In the last 20 years, several techniques using dual frequency GNSS measurements have been developed to estimate the TEC. With these techniques, systematic errors are confined to at least - 2.5 and 2.5 TECU for a mid-latitude site, and to at least - 5.5 and 5 TECU for a low-latitude location. In the last decades, knowledge about the ionosphere has grown considerably thanks to the use of GNSS measurements, and in turn the GNSS have highly benefited from this improved knowledge. Nowadays the availability of triple frequency GNSS signals enables the development of new processing techniques. We have therefore dedicated this work to developing a TEC reconstruction methodology based on triple frequency GNSS measurements and aimed at improving the accuracy of the final TEC values with regards to existing techniques. The structure of this study is as follows. Firstly, we provide information about GNSS, focusing on concepts, definitions and assumptions which will be used throughout this study. Then, we introduce the concepts of ionospheric propagation of radio signals and give a review of the literature on existing techniques used to extract the TEC with dual frequency GNSS measurements. We further present the complete design of the triple frequency TEC reconstruction methodology. We start by giving the set of combinations which allows us to resolve the original integer ambiguities, then we address the principles of TEC reconstruction, and finally we give an accuracy assessment of the computed TEC values. We also present an innovative technique to calibrate the satellite and receiver code hardware delays. We continue with testing the features developed on a simulated GPS and Galileo observation dataset, as well as on a real GIOVE observation dataset. Finally, we conclude this work by providing a critical overview of our investigations and suggesting various improvements of the current limitations. [less ▲]

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See detailAnalysis of longitudinal imaging data
Guillaume, Bryan ULiege

Speech/Talk (2012)

Detailed reference viewed: 20 (1 ULiège)
See detailHypertriglycéridémie et rein
Krzesinski, Jean-Marie ULiege

Conference (2012, January 24)

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See detailNanotechnologies, et alors?
Thoreau, François ULiege

Conference given outside the academic context (2012)

Detailed reference viewed: 32 (2 ULiège)
See detailGustave Serrurier-Bovy : architecte et designer d'un art nouveau
Folville, Xavier ULiege

Scientific conference (2012, January 24)

Présentation de l’œuvre de l'architecte et designer liégeois Gustave Serrurier-Bovy (1852-1910)

Detailed reference viewed: 29 (3 ULiège)
See detailImproved Domain Decomposition Method for the Helmholtz Equation"
Geuzaine, Christophe ULiege; Antoine, X.; Boubendir, Y. et al

Scientific conference (2012, January 23)

Detailed reference viewed: 44 (3 ULiège)
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See detailMoving Between Worlds: 'The Arrival'
Dony, Christophe ULiege

in The Comics Grid: Journal of Comics Scholarship. Year One (2012), 1

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See detail(R)évolutions dans la gestion des eaux de surface
Dewals, Benjamin ULiege

Scientific conference (2012, January 23)

Detailed reference viewed: 43 (15 ULiège)
See detailLa régionalisation de l'impôt des personnes physiques
Bourgeois, Marc ULiege

Scientific conference (2012, January 23)

Detailed reference viewed: 38 (5 ULiège)
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See detailApproches multi-échelles et éléments finis Solid-Shell
Duchene, Laurent ULiege

Speech/Talk (2012)

Detailed reference viewed: 15 (6 ULiège)
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See detailIR and UV spectroscopy of DNA Higher-Order Structures in the gas phase
Rosu, Frédéric ULiege; De Pauw, Edwin ULiege; Gabelica, Valérie ULiege et al

Conference (2012, January 22)

Detailed reference viewed: 23 (2 ULiège)