References of "2012"
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See detailAspects neurologiques associés au Syndrome de Down
Vaessen; Daron, aurore; DUBRU, Jean-Marie ULg et al

in Tijdschrift van de Belgische Kinderarts = Journal du Pédiatre Belge (2012), 14(2), 40-43

Summary : Down syndrome is one of best caracterized genetic syndromes. Its phenotype includes specific morphological features, mental retardation and several organic impairments such as cardiac ... [more ▼]

Summary : Down syndrome is one of best caracterized genetic syndromes. Its phenotype includes specific morphological features, mental retardation and several organic impairments such as cardiac malformations, cutaneous disorders and immunologic abnormalities. Beside these disturbances neurological disorders have been less considered or thought to be the expression of the mental retardation. However it is important to pay attention to the high incidence of epilepsy such as West syndrome in infants and “Late-Onset of myoclonic epilepsy in Down Syndrome” in the adult. They might required specific treatment. ADHD as well as autistic behavior may be difficult to diagnose especially in children with severe mental retardation. They need precise attention and rigourous follow-up of their treatment. [less ▲]

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See detailLe théorème de Lagrange en mathématiques et en économie : une étude didactique du savoir enseigné
Henry, Valérie ULg; Xhonneux, Sebastian

in Actes du Colloque EMF 2012 (2012)

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See detailPostface
Demoulin, Laurent ULg; Sindaco, Sarah ULg

in Sang de chien. Les morts sentent bon (2012)

Ce texte est la postface qui suit la réédition de deux romans d'Eugène Savitzkaya: Sang de chien et Les morts sentent bon. Ces deux romans sont situés au sein de l'ensemble de l'oeuvre. Leurs ... [more ▼]

Ce texte est la postface qui suit la réédition de deux romans d'Eugène Savitzkaya: Sang de chien et Les morts sentent bon. Ces deux romans sont situés au sein de l'ensemble de l'oeuvre. Leurs caractéristiques propres sont ensuite soulignées: il s'agit en quelque sorte de romans intermédiaires dans le parcours de l'écrivain. [less ▲]

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See detailLinear magnetoelectric effect by orbital magnetism
Scaramucci, A.; Bousquet, Eric ULg; Fechner, M. et al

in Physical Review Letters (2012), 109(19),

We use symmetry analysis and first-principles calculations to show that the linear magnetoelectric effect can originate from the response of orbital magnetic moments to the polar distortions induced by an ... [more ▼]

We use symmetry analysis and first-principles calculations to show that the linear magnetoelectric effect can originate from the response of orbital magnetic moments to the polar distortions induced by an applied electric field. Using LiFePO 4 as a model compound we show that spin-orbit coupling partially lifts the quenching of the 3d orbitals and causes small orbital magnetic moments (μ (L)≈0.3μ B) parallel to the spins of the Fe2 + ions. An applied electric field E modifies the size of these orbital magnetic moments inducing a net magnetization linear in E. © 2012 American Physical Society. [less ▲]

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See detailBioindicator of Genotoxicity: the Allium cepa test
Tedesco, S; Laughinghouse IV, Haywood ULg

in Srivastava, J.K. (Ed.) Environmental Contamination (2012)

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See detailThe sheepshead minnow Cyprinodon variegatus as a marine vertebrate model for investigating endocrine disrupting effects of triclosan
Schnitzler, Joseph ULg; Gauthray, Ghislain ULg; Silvestre, Frédéric et al

Poster (2012)

Zebrafish (Danio rerio) has been a prominent model in toxicology. This freshwater species present many advantages both in identifying endpoints of toxicity and in elucidating mechanisms of toxicity ... [more ▼]

Zebrafish (Danio rerio) has been a prominent model in toxicology. This freshwater species present many advantages both in identifying endpoints of toxicity and in elucidating mechanisms of toxicity. However, marine toxicologists lack such omnipotent model displaying similar advantages to zebrafish: small size, rapid breeding, and easy maintenance. We propose here the use of the sheepshead minnow Cyprinodon variegatus to define thyroid-disrupting effects of triclosan during pre-hatching development. Three females and two males were placed in each of the three breeding chambers designed for this experiment. More than 300 eggs were collected over three days and maintained in seawater with triclosan concentrations at 0, 100 ng.L-1, and 100 µg.L-1. Exposure of larvae to triclosan lasted until hatching. After hatching (six days post-spawning), 5 larvae per condition were placed in Bouin’s fixative for brain and thyroid histology. Length and body mass were measured. The body was frozen at -80oC to determine muscle thyroid hormone levels (T3 and T4), using radio-immunoassay techniques. Hatching success, in vivo observations, gross observation, thyroid hormone levels, histology will be determined and discussed in the framework of whether or not triclosan may alter thyroid metabolism during pre-hatching period of the sheepshead minnow. [less ▲]

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See detailInternationaal privaatrecht geannoteerd
Wautelet, Patrick ULg; Kruger, Thalia; Verhellen, Jinske et al

Book published by La Charte (2012)

This collection presents the most important statutory materials useful for the practice in Belgium of private international law. Each instrument (Belgian Acts, European Regulations and International ... [more ▼]

This collection presents the most important statutory materials useful for the practice in Belgium of private international law. Each instrument (Belgian Acts, European Regulations and International Conventions in force in Belgium) is reproduced together with comments highlighting the most important case law in relation to the provisions studied. [less ▲]

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See detailLes défis d'une formation universitaire clinique en logopédie
Schelstraete, Marie-Anne; Maillart, Christelle ULg

in Estienne, Françoise; Vanderlinden, Fabienne (Eds.) Pratiquer l'orthophonie. Expériences et savoir-faire de 33 orthophonistes. (2012)

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See detailExperimental study of the hydraulic behaviour of Piano Key Weirs
Machiels, Olivier ULg

Doctoral thesis (2012)

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See detailEORTC Radiation Oncology Group quality assurance platform: Establishment of a digital central review facility
Fairchild, A.; Aird, E.; Fenton, P. A. et al

in Radiotherapy & Oncology (2012), 103(3), 279-286

Objective: Quality assurance (QA) in clinical trials is essential to ensure treatment is safely and effectively delivered. As QA requirements have increased in complexity in parallel with evolution of ... [more ▼]

Objective: Quality assurance (QA) in clinical trials is essential to ensure treatment is safely and effectively delivered. As QA requirements have increased in complexity in parallel with evolution of radiation therapy (RT) delivery, a need to facilitate digital data exchange emerged. Our objective is to present the platform developed for the integration and standardization of QART activities across all EORTC trials involving RT. Methods: The following essential requirements were identified: secure and easy access without on-site software installation; integration within the existing EORTC clinical remote data capture system; and the ability to both customize the platform to specific studies and adapt to future needs. After retrospective testing within several clinical trials, the platform was introduced in phases to participating sites and QART study reviewers. Results: The resulting QA platform, integrating RT analysis software installed at EORTC Headquarters, permits timely, secure, and fully digital central DICOM-RT based data review. Participating sites submit data through a standard secure upload webpage. Supplemental information is submitted in parallel through web-based forms. An internal quality check by the QART office verifies data consistency, formatting, and anonymization. QART reviewers have remote access through a terminal server. Reviewers evaluate submissions for protocol compliance through an online evaluation matrix. Comments are collected by the coordinating centre and institutions are informed of the results. Conclusions: This web-based central review platform facilitates rapid, extensive, and prospective QART review. This reduces the risk that trial outcomes are compromised through inadequate radiotherapy and facilitates correlation of results with clinical outcomes. © 2012 Elsevier Ireland Ltd. All rights reserved. [less ▲]

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See detailQuel Musée de Beaux-Arts pour quel art contemporain ?,
Bawin, Julie ULg

in Du Musée des Beaux-Arts au Musée des Beaux-Arts (2012)

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See detailA Review of Known and Hypothetical Transmission Routes for Noroviruses
Mathijs, E.; Stals, A.; Baert, L. et al

in Food and Environmental Virology (2012), 4(4), 131-152

Human noroviruses (NoVs) are considered a worldwide leading cause of acute non-bacterial gastroenteritis. Due to a combination of prolonged shedding of high virus levels in feces, virus particle shedding ... [more ▼]

Human noroviruses (NoVs) are considered a worldwide leading cause of acute non-bacterial gastroenteritis. Due to a combination of prolonged shedding of high virus levels in feces, virus particle shedding during asymptomatic infections, and a high environmental persistence, NoVs are easily transmitted pathogens. Norovirus (NoV) outbreaks have often been reported and tend to affect a lot of people. NoV is spread via feces and vomit, but this NoV spread can occur through several transmission routes. While person-to-person transmission is without a doubt the dominant transmission route, human infective NoV outbreaks are often initiated by contaminated food or water. Zoonotic transmission of NoV has been investigated, but has thus far not been demonstrated. The presented review aims to give an overview of these NoV transmission routes. Regarding NoV person-to-person transmission, the NoV GII. 4 genotype is discussed in the current review as it has been very successful for several decades but reasons for its success have only recently been suggested. Both pre-harvest and post-harvest contamination of food products can lead to NoV food borne illness. Pre-harvest contamination of food products mainly occurs via contact with polluted irrigation water in case of fresh produce or with contaminated harvesting water in case of bivalve molluscan shellfish. On the other hand, an infected food handler is considered as a major cause of post-harvest contamination of food products. Both transmission routes are reviewed by a summary of described NoV food borne outbreaks between 2000 and 2010. A third NoV transmission route occurs via water and the spread of NoV via river water, ground water, and surface water is reviewed. Finally, although zoonotic transmission remains hypothetical, a summary on the bovine and porcine NoV presence observed in animals is given and the presence of human infective NoV in animals is discussed. © 2012 Springer Science+Business Media New York. [less ▲]

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See detailPrevalence of naturally occuring cartilage defects in the ovine stifle
Pierson, Audrey ULg; Muylkens, Benoît ULg; Hontoir, Fanny et al

Poster (2012)

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See detailExperimental and theoretical radiative properties of odd-parity highly excited levels in Mo II
Jiang, L; Wang, Q; Feng, Y et al

in European Physical Journal D -- Atoms, Molecules, Clusters & Optical Physics (2012), 66

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See detailLe cas clinique du mois: Implantation fortuite d'une sonde de defibrillation dans le ventricule gauche au travers d'un foramen ovale permeable.
Bologne, J.C.; Garweg, C.; LANCELLOTTI, Patrizio ULg et al

in Revue Médicale de Liège (2012), 67(2), 58-60

Inadvertent insertion of a defibrillation lead in the left ventricle is a rare complication generally underdiagnosed after device implantation. Management is not strictly codified due to the small number ... [more ▼]

Inadvertent insertion of a defibrillation lead in the left ventricle is a rare complication generally underdiagnosed after device implantation. Management is not strictly codified due to the small number of observed cases. We report the case of a 78 year-old man in whom the diagnosis has been performed lately during an echocardiography. [less ▲]

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See detailThe Denticulate Mousterian as a supposedly distinct facies in Western Central Asia
Kolobova, K; Krivoshapkin, A; Pavlenok, K et al

in Archaeology, Ethnology & Anthropology of Eurasia (2012), 40(1),

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See detailCe que voir veut dire: Essai sur la perception
Seron, Denis ULg

Book published by Le Cerf (2012)

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See detailNuclear export of histone deacetylase 7 during thymic selection is required for immune self-tolerance.
Kasler, Herbert G.; Lim, Hyung W.; Mottet, Denis ULg et al

in EMBO Journal (2012)

Histone deacetylase 7 (HDAC7) is a T-cell receptor (TCR) signal-dependent regulator of differentiation that is highly expressed in CD4/CD8 double-positive (DP) thymocytes. Here, we examine the effect of ... [more ▼]

Histone deacetylase 7 (HDAC7) is a T-cell receptor (TCR) signal-dependent regulator of differentiation that is highly expressed in CD4/CD8 double-positive (DP) thymocytes. Here, we examine the effect of blocking TCR-dependent nuclear export of HDAC7 during thymic selection, through expression of a signal-resistant mutant of HDAC7 (HDAC7-DeltaP) in thymocytes. We find that HDAC7-DeltaP transgenic thymocytes exhibit a profound block in negative thymic selection, but can still undergo positive selection, resulting in the escape of autoreactive T cells into the periphery. Gene expression profiling reveals a comprehensive suppression of the negative selection-associated gene expression programme in DP thymocytes, associated with a defect in the activation of MAP kinase pathways by TCR signals. The consequence of this block in vivo is a lethal autoimmune syndrome involving the exocrine pancreas and other abdominal organs. These experiments establish a novel molecular model of autoimmunity and cast new light on the relationship between thymic selection and immune self-tolerance. [less ▲]

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