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See detailChronostratigraphic context of the Middle to Upper Palaeolithic transition. Recent data from Belgium
Pirson, Stéphane; Flas, Damien ULg; Abrams, Grégory et al

in Quaternary International (2012), 259

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See detailSeeking for the optimum retrieval strategy of methanol (CH3OH) from ground-based high-resolution FTIR solar observations recorded at the high-altitude Jungfraujoch station (46.5ºN)
Mahieu, Emmanuel ULg; Bader, Whitney ULg; Lejeune, Bernard ULg et al

in Geophysical Research Abstracts (2012), 14

Methanol (CH3OH) is a key organic compound in the Earth’s troposphere, with reported concentrations of the order of a few ppbv. It is indeed the second most abundant organic atmospheric compound after ... [more ▼]

Methanol (CH3OH) is a key organic compound in the Earth’s troposphere, with reported concentrations of the order of a few ppbv. It is indeed the second most abundant organic atmospheric compound after methane (Jacob et al., 2005). The same authors have estimated its lifetime to a few days. Natural sources of CH3OH include plant growth, oceans, decomposition of plant matter, oxidation of methane,. . . They are complemented by anthropogenic (from vehicles, industry) and biomass burning emissions. Oxidation by the hydroxyl radical is the main sink, leading to the formation of carbon monoxide (CO) and formaldehyde (H2CO) (Rinsland et al., 2009; Stavrakou et al., 2011, and references therein). The first retrievals of methanol from ground-based Fourier Transform Infrared (FTIR) spectra have been reported by Rinsland et al. (2009), using spectra recorded at Kitt Peak (31.9ºN) and a microwindow extending from 992 to 999 cm-1. Soon after, Stavrakou et al. (2011) used another spectral interval from 1029 to 1037 cm-1, for methanol retrievals at Reunion Island (21ºS). In both cases, lines of the strong nu8 band of CH3OH were adjusted, accounting for interferences by several isotopologues of ozone and by water vapor. In this contribution, we will present first retrievals of CH3OH from observations recorded at the high-altitude station of the Jungfraujoch (46.5ºN, 8ºE, 3580 m asl), with a Bruker 120HR spectrometer, in the framework of the Network for the Detection of Atmospheric Composition Change (NDACC, visit http://www.ndacc.org). We will implement existing retrieval approaches –and possibly additional one(s)– to determine which strategy is the most appropriate for our dry high-altitude site. If successful, a long-term CH3OH total column time series will be produced using the Jungfraujoch observational database, and we will perform preliminary investigations to characterize the seasonal and inter-annual variations of this species at northern mid-latitudes. [less ▲]

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See detailParticle packing density and limestone fillers for more sustainable cement
He, Huan ULg; Courard, Luc ULg; Pirard, Eric ULg

in Key Engineering Materials [=KEM] (2012), 517

Cement blending with mineral admixtures, especially with byproduct or waste product powder, can effectively reduce consumption of cement and promote the ecology. Recently, an innovative concept was ... [more ▼]

Cement blending with mineral admixtures, especially with byproduct or waste product powder, can effectively reduce consumption of cement and promote the ecology. Recently, an innovative concept was proposed to replace of “coarse” cement grains by the inert fillers for sustainable cement in the low w/c concrete cement. As a basic mechanism, particle packing plays an important role in such replacement or blending. In the first part of study, the paper discusses the particle packing aspect of cement grains, limestone filler (LF) and LF blended cement. The new developed wet packing method and a dry packing method are proposed for the evaluation purpose. The paper presents results of packing tests with the influences of PSD, cement type, vibration, mixing, blending proportions, etc. The advantages and limitations of two packing methods are also discussed in this paper. [less ▲]

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See detailLa Tâche Du Château : construction d’un outil d’exploration métaphorique pour l’enfant victime d’abus sexuel.
Bullens, Quentin ULg

in Neuropsychiatrie de l'Enfance et de l'Adolescence (2012), 60(6), 461-467

In therapy, asking about the sexual abuse facts known by the child can sometimes appear like additional maltreatment. On the other hand, not talk about it could also mean not to be interested or not being ... [more ▼]

In therapy, asking about the sexual abuse facts known by the child can sometimes appear like additional maltreatment. On the other hand, not talk about it could also mean not to be interested or not being able to do so and therefore, not being a big help for the child victim. Despite the various recommendations in the treatment of children victims of sexual abuse, it seems to continue to be unclear how therapist should address these facts in the therapeutic process and that, whatever its orientation. We wanted to present what we call here The Castle Task, based on Winnicott’s Self-concept and the structuralist approach of family by Minuchin. We believe it allows the child to address their traumatic experience indirectly and therefore to explore without fear of exposure. [less ▲]

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See detailOptimization of thermal material in a flux pump system with high temperature superconductor
Hsu, C. H.; Yan, Y; Hadeler, O. et al

in IEEE Transactions on Applied Superconductivity (2012), 22(3), 7800404

Superconductors are known for the ability to trap magnetic field. A thermally actuated magnetization (TAM) flux pump is a system that utilizes the thermal material to generate multiple small magnetic ... [more ▼]

Superconductors are known for the ability to trap magnetic field. A thermally actuated magnetization (TAM) flux pump is a system that utilizes the thermal material to generate multiple small magnetic pulses resulting in a high magnetization accumulated in the superconductor. Ferrites are a good thermal material candidate for the future TAM flux pumps because the relative permeability of ferrite changes significantly with temperature, particularly around the Curie temperature. Several soft ferrites have been specially synthesized to reduce the cost and improve the efficiency of the TAM flux pump. Various ferrite compositions have been tested under a temperature variation ranging from 77K to 300K. The experimental results of the synthesized soft ferrites-Cu0.3Zn0.7Ti0.04Fe1.96O4, including the Curie temperature, magnetic relative permeability and the volume magnetization (emu/cm3), are presented in this paper. The results are compared with original thermal material, gadolinium, used in the TAM flux pump system.-Cu0.3Zn0.7Ti0.04Fe1.96O4 holds superior characteristics and is believed to be a suitable material for next generation TAM flux pump. © 2011 IEEE. [less ▲]

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See detailNormal and pathological aging and memory
Bastin, Christine ULg

Scientific conference (2012)

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See detailChemical contamination along the Mediterranean French coast using Posidonia oceanica (L.) Delile above-ground tissues: a multiple trace element study
Luy, Nicolas; Gobert, Sylvie ULg; Sartoretto, Stéphane et al

in Ecological Indicators (2012), 18

Levels of Be, Al, V, Mn, Co, As, Se, Mo, Ag, Sn, Sb, Bi as well as of Cr, Fe, Ni, Cu, Zn, Cd and Pb in Posidonia oceanica (L.) Delile from the Mediterranean French coast were analysed using DRC ICP-MS ... [more ▼]

Levels of Be, Al, V, Mn, Co, As, Se, Mo, Ag, Sn, Sb, Bi as well as of Cr, Fe, Ni, Cu, Zn, Cd and Pb in Posidonia oceanica (L.) Delile from the Mediterranean French coast were analysed using DRC ICP-MS. The first twelve elements have not been well studied and can be considered to be potential pollutants as a result of potentially increased levels resulting from anthropogenic activities. Spatial variation and/or compartmentalization were found for all trace elements. Except for Al, Cr, Fe, Cu and Ag, most trace elements were preferentially accumulated in photosynthetic tissues, suggesting uptake from the water column. Moreover, for Be, V, Mn, Co, Ni, As, Mo, Sb, Sn and Pb, adult leaves had higher levels than intermediate leaves, suggesting low kinetics of accumulation. Levels in the third intermediate leaf were representative of the average levels of the integral shoot, and thus can be used alone in chemical biomonitoring. For most of the twelve little-studied trace elements, the background levels of the northwestern Mediterranean Sea can be measured, and their spatial variation can be related to anthropogenic activities. Levels of the seven widely studied trace elements seem to decrease or stabilize over time, probably due to their reduced anthropogenic use. These observations show that P. oceanica is a sensitive bioindicator for the monitoring of chemical contamination of a large number of trace elements. [less ▲]

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See detailAutomatic Aircraft Load Planning
Limbourg, Sabine ULg; Schyns, Michael ULg; Laporte, Gilbert

in Journal of the Operational Research Society (2012), 63

The goal of this paper is the development of a new mixed integer linear program designed for optimally loading a set of containers and pallets into a compartmentalised cargo aircraft. It is based on real ... [more ▼]

The goal of this paper is the development of a new mixed integer linear program designed for optimally loading a set of containers and pallets into a compartmentalised cargo aircraft. It is based on real-world problems submitted by a professional partner. This model takes into account strict technical and safety constraints. In addition to the standard goal of optimally positioning the centre of gravity, we also propose a new approach based on the moment of inertia. This double goal implies an increase in aircraft efficiency and a decrease in fuel consumption. Cargo loading generally remains a manual, or at best a computer assisted, and time consuming task. A fully automatic software was developed to quickly compute optimal solutions. Experimental results show that our approach achieves better solutions than manual planning, within only a few seconds. [less ▲]

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See detailWhat is the Contribution of Host-Derived CMV Immunity after Allogeneic Transplantation following Non-Myeloablative Conditioning?
MENTEN, Catherine ULg; Castermans, E.; Hannon, Muriel ULg et al

in Haematologica (2012), 97(Supplement 1), 720

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See detailDisease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster
Kumita, Janet R.; Helmfors, Linda; Williams, Jocy et al

in FASEB Journal (2012)

We have created a Drosophila model of lysozyme amyloidosis to investigate the in vivo behavior of disease-associated variants. To achieve this objective, wild-type (WT) protein and the amyloidogenic ... [more ▼]

We have created a Drosophila model of lysozyme amyloidosis to investigate the in vivo behavior of disease-associated variants. To achieve this objective, wild-type (WT) protein and the amyloidogenic variants F57I and D67H were expressed in Drosophila melanogaster using the UAS-gal4 system and both the ubiquitous and retinal expression drivers Act5C-gal4 and gmr-gal4. The nontransgenic w(1118) Drosophila line was used as a control throughout. We utilized ELISA experiments to probe lysozyme protein levels, scanning electron microscopy for eye phenotype classification, and immunohistochemistry to detect the unfolded protein response (UPR) activation. We observed that expressing the destabilized F57I and D67H lysozymes triggers UPR activation, resulting in degradation of these variants, whereas the WT lysozyme is secreted into the fly hemolymph. Indeed, the level of WT was up to 17 times more abundant than the variant proteins. In addition, the F57I variant gave rise to a significant disruption of the eye development, and this correlated to pronounced UPR activation. These results support the concept that the onset of familial amyloid disease is linked to an inability of the UPR to degrade completely the amyloidogenic lysozymes prior to secretion, resulting in secretion of these destabilized variants, thereby leading to deposition and associated organ damage.-Kumita, J. R., Helmfors, L., Williams, J., Luheshi, L. M., Menzer, L., Dumoulin, M., Lomas, D. A., Crowther, D. C., Dobson, C. M., Brorsson, A.-C. Disease-related amyloidogenic variants of human lysozyme trigger the unfolded protein response and disturb eye development in Drosophila melanogaster. [less ▲]

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See detailL’éternel retour du "travail des enfants" dans les politiques publiques au Burkina Faso : perspective historique
Wouango, Joséphine ULg

in Bonnet, Doris; Rollet, Cathérine; De Suremain, Charles Édouard (Eds.) Modèles d'enfance (2012)

Dans une perspective historique, ce chapitre cherche à comprendre comment le travail des enfants a été construit comme « problème » dans les politiques publiques au Burkina Faso. En remontant aux ... [more ▼]

Dans une perspective historique, ce chapitre cherche à comprendre comment le travail des enfants a été construit comme « problème » dans les politiques publiques au Burkina Faso. En remontant aux politiques coloniales françaises dans le pays, il se propose de répondre à la question suivante : face à l’émergence et au renforcement des politiques publiques de lutte contre le travail des enfants, assiste-t-on à une disparition du modèle de l’enfant du lignage qui percevait l’enfant comme une « richesse » et une force de travail complémentaire? Le chapitre présente d’abord la construction progressive du travail des enfants en « problème » de politiques publiques pendant la colonisation. Il analyse ensuite l’évolution et la portée de l’intervention des gouvernements successifs après l’indépendance pour imposer une nouvelle vision de l’enfant (l’enfant de la Nation). Enfin, il révèle que malgré l’engouement récent pour la prise en compte du point de vue l’enfant, le statut de l’enfant travailleur comme sujet peine à être reconnu. L’analyse globale montre une tension permanente, à des degrés différents, entre les modèles de l’enfant de la nation, de l’enfant du lignage et de l’enfant sujet : ce qui traduit aussi la complexité du travail des enfants et de sa lutte au Burkina Faso contemporain. Le texte est issu d’un travail de terrain mené au Burkina Faso en 2008 et 2009 dans le cadre de notre thèse. [less ▲]

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See detailThe Pivotal Role of Mössbauer Spectroscopy in the Characterization of Prussian Blue and Related Iron Cyanide Complexes
Grandjean, Fernande ULg; Long, Gary J; Samain, Louise ULg

in Mössbauer Effect Reference and Data Journal (2012)

For 50 years, 57Fe Mössbauer spectroscopy has played a pivotal role in the characterization of Prussian blue complexes and many related iron cyanide complexes, a pivotal role that is extensively ... [more ▼]

For 50 years, 57Fe Mössbauer spectroscopy has played a pivotal role in the characterization of Prussian blue complexes and many related iron cyanide complexes, a pivotal role that is extensively illustrated in this paper. For the benefit of the young Mössbauer spectroscopists, the successes, the failures, and the pitfalls reported in the literature are discussed. The successes include the unquestionable distinction of iron oxidation and spin states in Prussian blue and the determination that Prussian blue and Turnbull's blue are the same. The failures include the distinction between low-spin FeII and high-spin FeIIIcations in Berlin green. The pitfalls include many, sometimes poorly determined, hyperfine parameters that have been reported for complexes whose stoichiometry is either unknown or unspecified and even sometimes incorrect. [less ▲]

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See detailDetection and quantification of human papillomavirus in benign and malignant parotid lesions.
Descamps, Geraldine; Duray, Anaelle; Rodriguez, Alexandra et al

in Anticancer Research (2012), 32(9), 3929-32

Background/Aim: Human papillomavirus (HPV) is implicated in head and neck squamous cell carcinomas. However, the causal role of HPV in carcinomas of the parotid gland remains uncertain and less documented ... [more ▼]

Background/Aim: Human papillomavirus (HPV) is implicated in head and neck squamous cell carcinomas. However, the causal role of HPV in carcinomas of the parotid gland remains uncertain and less documented. This study aimed to determine the potential implication of HPV in the development of benign and malignant lesions of the parotid gland. MATERIALS AND METHODS: Paraffin-embedded biopsies were obtained from 40 patients with benign parotid gland tumors and from 39 patients with parotid gland carcinomas. The 79 samples were evaluated for the presence of HPV DNA using both GP5+/GP6+ consensus Polymerase Chain Reaction (PCR) and type-specific E6/E7 PCR to detect 18 HPV types. RESULTS: Our results showed a low prevalence of HPV, with only three HPV-positive cases among the 40 benign tumors and one infected carcinoma in the malignant population. CONCLUSION: No association between the presence of HPV DNA and the development of parotid gland tumors was found in our study. [less ▲]

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See detailExperimental and theoretical radiative properties of odd-parity highly excited levels in Mo II
Jiang, L; Wang, Q; Feng, Y et al

in European Physical Journal D -- Atoms, Molecules, Clusters & Optical Physics (2012), 66

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See detailPythium root rot of common bean : biology and control methods. A review
Nzungize, J.R.; Lyumugabe, F.; Busogoro, J.-P. et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2012), 16(3), 405-413

Pythium root rot constitutes a highly damaging constraint on the common bean, Phaseolus vulgaris L., grown in several areas of Eastern and Central Africa. Here, this food legume is cultivated intensively ... [more ▼]

Pythium root rot constitutes a highly damaging constraint on the common bean, Phaseolus vulgaris L., grown in several areas of Eastern and Central Africa. Here, this food legume is cultivated intensively under poor conditions of crop rotation due to the exiguity of the land in the region. Yield losses of up to 70 % in traditional local bean cultivars have been reported in Kenya and Rwanda. In this study, a detailed analysis of the biology and diversity of the Pythium genus was carried out in order to understand the mechanisms leading to the development of the disease. Various control methods for reducing the damage provoked by this disease were analyzed. [less ▲]

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See detailNew and Paradoxical Roles of Matrix Metalloproteinases in the Tumor Microenvironment.
Noël, Agnès ULg; Gutierrez-Fernandez, A; Sounni, Nor Eddine ULg et al

in Frontiers in Pharmacology of Anti-Cancer Drugs (2012), 3(140), 1

Processes such as cell proliferation, angiogenesis, apoptosis, or invasion are strongly influenced by the surrounding microenvironment of the tumor. Therefore, the ability to change these surroundings ... [more ▼]

Processes such as cell proliferation, angiogenesis, apoptosis, or invasion are strongly influenced by the surrounding microenvironment of the tumor. Therefore, the ability to change these surroundings represents an important property through which tumor cells are able to acquire specific functions necessary for tumor growth and dissemination. Matrix metalloproteinases (MMPs) constitute key players in this process, allowing tumor cells to modify the extracellular matrix (ECM) and release cytokines, growth factors, and other cell-surface molecules, ultimately facilitating protease-dependent tumor progression. Remodeling of the ECM by collagenolytic enzymes such as MMP1, MMP8, MMP13, or the membrane-bound MT1-MMP as well as by other membrane-anchored proteases is required for invasion and recruitment of novel blood vessels. However, the multiple roles of the MMPs do not all fit into a simple pattern. Despite the pro-tumorigenic function of certain metalloproteinases, recent studies have shown that other members of these families, such as MMP8 or MMP11, have a protective role against tumor growth and metastasis in animal models. These studies have been further expanded by large-scale genomic analysis, revealing that the genes encoding metalloproteinases, such as MMP8, MMP27, ADAM7, and ADAM29, are recurrently mutated in specific tumors, while several ADAMTSs are epigenetically silenced in different cancers. The importance of these proteases in modifying the tumor microenvironment highlights the need for a deeper understanding of how stroma cells and the ECM can modulate tumor progression. [less ▲]

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See detailHTLV-1 positive and negative T cells cloned from infected individuals display telomerase and telomere genes deregulation that predominate in activated but untransformed CD4+ T cells.
Zane, Linda; Sibon, David; CAPRARO, Valérie ULg et al

in International Journal of Cancer = Journal International du Cancer (2012), 131(4), 821-33

Untransformed HTLV-1 positive CD4(+) cells from infected individuals are selected for expressing tax and displaying morphological features consistent with telomere dysfunctions. We show that in resting ... [more ▼]

Untransformed HTLV-1 positive CD4(+) cells from infected individuals are selected for expressing tax and displaying morphological features consistent with telomere dysfunctions. We show that in resting HTLV-1 positive CD4(+) cells cloned from patients, hTERT expression parallels tax expression and cell cycling. Upon activation, these cells dramatically augment tax expression, whereas their increase in telomerase activity is about 20 times lower than that of their uninfected counterpart. Activated HTLV-1 positive CD4(+) but not uninfected CD4(+) or CD8(+) clones also repress the transcription of TRF1, TPP1, TANK1, POT1, DNA-PKc and Ku80. Both infected and uninfected lymphocytes from infected individuals shared common telomere gene deregulations toward a pattern consistent with premature senescence. ATLL cells displayed the highest telomerase activity (TA) whereas recovered a telomere gene transcriptome close to that of normal CD4(+) cells. In conclusion HTLV-1-dependent telomere modulations seem involved in clonal expansion, immunosuppression, tumor initiation and progression. [less ▲]

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See detailMediterranean lignocellulosic biomass delignification and lignin valorization into high-added value components
Manara, Panagiota; Richel, Aurore ULg; Zabaniotou, Anastasia

Conference (2012)

The present study approaches the extraction of lignin samples from several lignocellulosic renewable feedstocks, including raw materials from Greece. The valorization of these lignins samples into high ... [more ▼]

The present study approaches the extraction of lignin samples from several lignocellulosic renewable feedstocks, including raw materials from Greece. The valorization of these lignins samples into high-added value components will also be explored using chemical catalytic routes and “green chemistry” methodology. The present study is a collaboration of Biomass Group of Aristotle University of Thessaloniki, Greece and Gembloux Agro-Bio Tech, in the frame of UBIOCHEM COST ACTION C0903, performed at the Laboratories of Biological and Industrial Chemistry Unit, Gembloux Agro-Bio Tech, University of Liege with samples preparation at AUTh. The lignin extraction from lignocellulosic biomass takes place via chemical, thermal and mechanical routes, including acid or basic processes, steam cracking, steam explosion. Statistical approaches (i.e. response surface methodology) are used for the optimization of processing parameters. Physico-chemical characterization of lignin materials is considered using specific techniques developed by the research team of Agro-Bio-Tech Institute, including qualitative and quantitative mono- and bidimensionnal NMR spectroscopy, MALLS, FT-IR, TGA and chemical methods. The characterization of the lignocellulosic materials before and after pretreatment protocol is investigated regarding the determination of extractives, ash, total lignin contents, and structural carbohydrates as well as proteins contents. Chemical catalytic routes and “green chemistry” methodology is conducted in order to valorize lignin. [less ▲]

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