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See detailÉtendues de la réflexivité. Introduction
Badir, Sémir ULg; Mouratidou, Eleni

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2012), 3 (2010)

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See detailErrors in 2-D modelling using a 0th order turbulence closure for compound channel flows
Linde, F.; Paquier, A.; Proust, S. et al

in International Conference on Fluvial Hydraulics, River Flow 2012 (2012)

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows ... [more ▼]

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows, comparing the simulations with experiments. Three flow configurations are analyzed: uniform, gradually varied and rapidly varied flows. The last configuration is obtained by setting a transverse embankment on the flood plain. Errors are estimated on the sub-section mean velocity, discharge andwater depth, on the mixing layer width and on the depth-averaged stream-wise velocity and lateral shear stress. Depending on the flow configuration and on the studied parameter, relative errors significantly vary from nearly zero to 50%. The influence of the 0th order turbulence closure on the mean flow and the dimensions of the recirculation zone behind the embankment is also investigated, using either constant eddy viscosity or Elder's model. © 2012 Taylor & Francis Group, London. [less ▲]

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See detailNeural correlates of hypokinetic gait in Parkinson’s disease: An fMRI study
Cremers, Julien ULg; Stamatakis, Julien; D'Ostilio, Kevin ULg et al

Poster (2012)

Objective: To investigate the neural correlates of hypokinetic gait in Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI). Background: Although hypokinetic gait is frequent and ... [more ▼]

Objective: To investigate the neural correlates of hypokinetic gait in Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI). Background: Although hypokinetic gait is frequent and has a negative impact on quality of life in PD, its underlying mechanisms remain poorly understood. Assuming that the brain regions recruited during real and imagined gait strongly overlap, mental imagery of brisk gait may be a successful approach to study hypokinetic gait in PD. Methods: Fifteen ‘‘on-drugs’’ PD patients (8 males; mean age 5 65.1 6 9.4 years) and fifteen controls matched for age, gender and mental imagery skills were trained to perform video-taped trials of comfortable and brisk gait on a 25 meter-path. The study was organ- ized as a block-design fMRI experiment where subjects were instructed to rehearse themselves performing comfortable and brisk gait and to press a key to indicate when they completed each 25 meter-imagined gait trial. The imagined speed reserve (ISR) defined as the difference between imagined brisk and comfortable gait speeds was measured as a control of behavioral performance. Imaging data processing and analyses were performed using SPM8. The first-level individual contrast images representing the comparison between brisk and comfortable gait were entered as two separate groups (controls vs patients) in an ANOVA with the corresponding ISRs as correlation regressors. Results: Compared with controls, patients showed hypokinetic gait during real gait training as their increase in speed during brisk relatively to comfortable gait was related to an increase in step ca- dence (r50.87; p<0.001) but not in step length (r50.11). ISRs meas- ured during fMRI and their real counterparts measured offline strongly correlated in patients (r50.88; p<0.001) and controls (r50.59; p50.02). Between-group comparison (p<0.001, uncorrected) of fMRI data showed that increasing imagined gait speed was strongly associated with increased activity of the left posterior parietal cortex in controls and with decreased activity of this region in patients. Conclusions: Our findings suggest that hypokinetic gait in PD is related to the impaired functioning of the left posterior parietal cortex. This area may represent a target for therapeutic interventions aimed at alleviating gait disturbances in PD. [less ▲]

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See detailPrevalence and management of cancer-related anaemia, iron deficiency and the specific role of intravenous iron
Aapro, M.; Osterborg, A.; Gascon, P. et al

in Annals of Oncology (2012), 23

Background: Chronic diseases reduce the availability of iron for effective erythropoiesis. This review summarises clinical consequences of iron deficiency (ID) and anaemia in cancer patients, mechanisms ... [more ▼]

Background: Chronic diseases reduce the availability of iron for effective erythropoiesis. This review summarises clinical consequences of iron deficiency (ID) and anaemia in cancer patients, mechanisms how impaired iron homeostasis affects diagnosis and treatment of ID, and data from clinical trials evaluating i.v. iron with or without concomitant erythropoiesis-stimulating agents (ESAs). Design: Clinical trial reports were identified in PubMed and abstracts at relevant major congresses. Results: Reported prevalence of ID in cancer patients ranges from 32 to 60% and most iron-deficient patients are also anaemic. Randomised clinical trials have shown superior efficacy of i.v. iron over oral or no iron in reducing blood transfusions, increasing haemoglobin, and improving quality of life in ESA-treated anaemic cancer patients. Furthermore, i.v. iron without additional ESA should be evaluated as potential treatment in patients with chemotherapyinduced anaemia. At recommended doses, i.v. iron is well tolerated, particularly compared with oral iron. No serious drug-related adverse effects were seen during long-term use in renal disease and no effect on tumour growth has been observed in trials with anaemic cancer patients. Conclusions: Reliable diagnosis and treatment of ID are recommended key steps in modern cancer patient management to minimise impact on quality of life and performance status. [less ▲]

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See detailEfficient synthesis of 2,5-diketopiperazines by Staudinger-mediated cyclization
Beagle, Lucas; Hansen, Finn; Monbaliu, Jean-Christophe ULg et al

in Synlett (2012), 23(16), 2337-2340

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See detailLes organisations d'aide et soins à domicile: des entreprises à haute valeur ajoutée
Defourny, Jacques ULg

in La Revue de l'Aide et des Soins à Domicile (2012), 131(mai-juillet), 24-27

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See detailChirurgie metabolique: une place croissante dans le traitement du diabete.
De Flines, J.; Franck, M.; Rorive, M. et al

in Revue Médicale Suisse (2012), 8(351), 1621-41626-7

Bariatric surgery becomes more and more important in the management of the obese patient with type 2 diabetes, especially in case of failure of medical approaches. Metabolic improvement results not only ... [more ▼]

Bariatric surgery becomes more and more important in the management of the obese patient with type 2 diabetes, especially in case of failure of medical approaches. Metabolic improvement results not only from weight loss and the subsequent reduction in insulin resistance, but also from modifications of digestive hormones (especially incretins) that contribute to promote insulin secretion. This new paradigm, moving from bariatric surgery to metabolic surgery, opens new perspectives. The present article briefly describes innovative surgical techniques focusing on endocrine and metabolic improvement rather than on weight loss, the preliminary results of metabolic surgery in patients with type 2 diabetes and a body mass index <35 kg/m2 and, finally, some data regarding the surgical management of obese patients with type I diabetes not well treated with classical medical means. [less ▲]

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See detailMethod for the preliminary design of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Houille Blanche (2012), 4

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together ... [more ▼]

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together with its important discharge capacity for low heads, this geometric feature makes the PKW an interesting solution for dam rehabilitation. However, its hydraulic design remains problematic, even at a preliminary stage. This paper presents a preliminary design method based on results of experimental tests. The method enables to design project models by extrapolation of characteristics of existing idealized scale models. A practical application is presented to illustrate the method. [less ▲]

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See detailRecommandations Europeennes 2011 pour la prise en charge des maladies cardiovasculaires pendant la grossesse. Partie 2: Prise en charge de l'hypertension arterielle.
Moonen, Marie ULg; Legrand, D.; LANCELLOTTI, Patrizio ULg

in Revue Médicale de Liège (2012), 67(10), 509-12

In this article, we report the 2011 European guidelines on the management of cardiovascular diseases during pregnancy, with particular attention to the management of hypertension as hypertensive disorders ... [more ▼]

In this article, we report the 2011 European guidelines on the management of cardiovascular diseases during pregnancy, with particular attention to the management of hypertension as hypertensive disorders are the most frequent cardiovascular complications in pregnancy. [less ▲]

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See detailDistribution and origin of suspended matter and organic carbon pools in the Tana River Basin, Kenya
Tamooh, F; Van den Meersche, K; Meysman, F et al

in Biogeosciences (2012), 9

We studied patterns in organic carbon pools and their origin in the Tana River Basin (Kenya), in February 2008 (dry season), September–November 2009 (wet season), and June–July 2010 (end of wet season ... [more ▼]

We studied patterns in organic carbon pools and their origin in the Tana River Basin (Kenya), in February 2008 (dry season), September–November 2009 (wet season), and June–July 2010 (end of wet season), covering the full continuum from headwater streams to lowland mainstream sites. A consistent downstream increase in total suspended matter (TSM, 0.6 to 7058 mg l−1) and particulate organic carbon (POC, 0.23 to 119.8 mg l−1) was observed during all three sampling campaigns, particularly pronounced below 1000m above sea level, indicating that most particulate matter exported towards the coastal zone originated from the mid and low altitude zones rather than from headwater regions. This indicates that the cascade of hydroelectrical reservoirs act as an extremely efficient particle trap. Although 7Be / 210Pbxs ratios/age of suspended sediment do not show clear seasonal variation, the gradual downstream increase of suspended matter during end of wet season suggests its origin is caused by inputs of older sediments from bank erosion and/or river sediment resuspension. During wet season, higher TSM concentrations correspond with relatively young suspended matter, suggesting a contribution from recently eroded material.With the exception of reservoir waters, POC was predominantly of terrestrial origin as indicated by generally high POC : chlorophyll a (POC : Chl a) ratios (up to 41 000). Stable isotope signatures of POC ( 13CPOC) ranged between −32 and −20‰and increased downstream, reflecting an increasing contribution of C4-derived carbon in combination with an expected shift in 13C for C3 vegetation towards the more semi-arid lowlands. 13C values in sediments from the main reservoir (−19.5 to −15.7 ‰) were higher than those found in any of the riverine samples, indicating selective retention of particles associated with C4 fraction. Dissolved organic carbon (DOC) concentrations were highest during the end of wet season (2.1 to 6.9 mg l−1), with stable isotope signatures generally between −28 and −22 ‰. A consistent downstream decrease in % organic carbon (%OC) was observed for soils, riverine sediments, and suspended matter. This was likely due to better preservation of the organic fraction in colder high altitude regions, with loss of carbon during downstream spiraling. 13C values for soil and sediment did not exhibit clear altitudinal patterns, but values reflect the full spectrum from C3-dominated to C4-dominated sites. Very low ratios of organic carbon to mineral surface area (OC : SA) were found in reservoir sediments and suspended matter in the lower Tana River, indicating that these are stable OC pools which have undergone extensive degradation. Overall, our study demonstrates that substantial differences occur in both the quantities and origin of suspended sediments and organic carbon along the river profile in this tropical river basin, as well as seasonal differences in the mechanisms causing such variations. [less ▲]

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See detailSimulation de la croissance du blé à l’aide de modèles écophysiologiques : Synthèse bibliographique des méthodes, potentialités et limitations.
Dumont, Benjamin ULg; Vancutsem, Françoise ULg; Seutin, Benoit ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2012), 16(3), 376-386

Crop models describe the growth and development of a crop interacting with its surrounding agro-environmental conditions (soil, climate and close conditions of the plant). However, the implementation of ... [more ▼]

Crop models describe the growth and development of a crop interacting with its surrounding agro-environmental conditions (soil, climate and close conditions of the plant). However, the implementation of such models remains difficult because of the high number of explanatory variables and parameters. It often happens that important discrepancies appear between measured and simulated values. This article aims to highlight the different sources of uncertainty related to the use of crop models, as well as the actual methods that allow to compensate or, at least, to consider these sources of error during the model result analysis. This article presents a literature review that firstly synthetises the general mathematical structure of crop models. The main criteria for evaluating crop models are then described. Finally, several methods used for improving models are given. Parameter estimation methods, including frequentist and Bayesian approaches, are presented and data assimilation methods are reviewed. [less ▲]

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See detailNécrologie Jacques Stiennon (1920-2012)
George, Philippe ULg

in Cahiers de Civilisation Médiévale (2012), 55

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See detailStructure géométrique de l’ADN
Thiry, Marc ULg

Conference (2012)

L’ADN rassemble les informations nécessaires à tout organisme vivant pour survivre et se reproduire. Ce grimoire vient de ses ancêtres et sera transmis à ses descendants sous une forme légèrement remaniée ... [more ▼]

L’ADN rassemble les informations nécessaires à tout organisme vivant pour survivre et se reproduire. Ce grimoire vient de ses ancêtres et sera transmis à ses descendants sous une forme légèrement remaniée. La géométrie intervient à plusieurs stades de ce processus. [less ▲]

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See detailAdaptation of a Murine Chronic GVH Model to Study Graft versus Myeloma Effect after Allogeneic Transplantation
Binsfeld, Marilène ULg; Belle, Ludovic ULg; Hannon, Muriel ULg et al

in Belgian Journal of Hematology (2012), Abstracts book(Supplement of 27th General Meeting of the Belgian Hematological Society), 16

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See detailCentre Pilote wallon des céréales et oléo-protéagineux - Rapport de synthèse 2012
Bodson, Bernard ULg; Meza Morales, Walter; Monfort, Bruno et al

Report (2012)

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See detailAvant-propos : mises au point et mises à jour
Lecocq, Pascale ULg

in Lecocq, Pascale (Ed.) La copropriété par appartements. Deux ans après la réforme (2012)

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