References of "2012"
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See detailÉtendues de la réflexivité. Introduction
Badir, Sémir ULg; Mouratidou, Eleni

in MethIS : Méthodes et Interdisciplinarité en Sciences Humaines (2012), 3 (2010)

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See detailL'asthme: une maladie complexe mettant en jeu facteurs environnementaux et terrain genetique.
LOUIS, Renaud ULg; SCHLEICH, FLorence ULg; Corhay, Jean-Louis ULg et al

in Revue Médicale de Liège (2012), 67(5-6), 286-91

Asthma is a complex disease highly dependent of environmental exposure and genetic background. Through linkage analysis, positional cloning and genome wide association studies, novel asthma genes have ... [more ▼]

Asthma is a complex disease highly dependent of environmental exposure and genetic background. Through linkage analysis, positional cloning and genome wide association studies, novel asthma genes have come out such as ADAM-33 or ORMLD3. Important environmental factors include allergenic exposure, pollutants and especially particulate matters, tobacco, aerosol exposure, viral infections and level of exposure to endotoxin. The effects of environmental factors are modulated by the genetic sequence and numerous single nucleotide polymorphisms (SNPs). Recently, it has also become clear that environmental factors may alter gene expression by DNA methylation or histone methylation/acetylation without changing the gene sequence and thereby changing asthmatic phenotype. [less ▲]

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See detailMô hình phân tích cầu tiêu dùng thịt gia cầm tại Hà Nội
Vu Dinh, Ton; Phan Dang, Thang; Do Duc, Luc et al

in Nghiên cứu Kinh tế" - Viện kinh tế Việt Nam (= Economic studies) (2012), (405 (2-2012)), 59-68

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See detailRobust transformation procedure for the production of transgenic farmer-preferred cassava landraces.
Zainuddin, Ima M.; Schlegel, Kim; Gruissem, Wilhelm et al

in Plant methods (2012), 8(1), 24

Recent progress in cassava transformation has allowed the robust production of transgenic cassava even under suboptimal plant tissue culture conditions. The transformation protocol has so far been used ... [more ▼]

Recent progress in cassava transformation has allowed the robust production of transgenic cassava even under suboptimal plant tissue culture conditions. The transformation protocol has so far been used mostly for the cassava model cultivar 60444 because of its good regeneration capacity of embryogenic tissues. However, for deployment and adoption of transgenic cassava in the field it is important to develop robust transformation methods for farmer- and industry-preferred landraces and cultivars. Because dynamics of multiplication and regeneration of embryogenic tissues differ between cassava genotypes, it was necessary to adapt the efficient cv. 60444 transformation protocol to genotypes that are more recalcitrant to transformation. Here we demonstrate that an improved cassava transformation protocol for cv. 60444 could be successfully modified for production of transgenic farmer-preferred cassava landraces. The modified transformation method reports on procedures for optimization and is likely transferable to other cassava genotypes reportedly recalcitrant to transformation provided production of high quality FEC. Because the three farmer-preferred cassava landraces selected in this study have been identified as resistant or tolerant to cassava mosaic disease (CMD), the adapted protocol will be essential to mobilize improved traits into cassava genotypes suitable for regions where CMD limits production. [less ▲]

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See detailNeural correlates of hypokinetic gait in Parkinson’s disease: An fMRI study
Cremers, Julien ULg; Stamatakis, Julien; D'Ostilio, Kevin ULg et al

Poster (2012)

Objective: To investigate the neural correlates of hypokinetic gait in Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI). Background: Although hypokinetic gait is frequent and ... [more ▼]

Objective: To investigate the neural correlates of hypokinetic gait in Parkinson’s disease (PD) using functional magnetic resonance imaging (fMRI). Background: Although hypokinetic gait is frequent and has a negative impact on quality of life in PD, its underlying mechanisms remain poorly understood. Assuming that the brain regions recruited during real and imagined gait strongly overlap, mental imagery of brisk gait may be a successful approach to study hypokinetic gait in PD. Methods: Fifteen ‘‘on-drugs’’ PD patients (8 males; mean age 5 65.1 6 9.4 years) and fifteen controls matched for age, gender and mental imagery skills were trained to perform video-taped trials of comfortable and brisk gait on a 25 meter-path. The study was organ- ized as a block-design fMRI experiment where subjects were instructed to rehearse themselves performing comfortable and brisk gait and to press a key to indicate when they completed each 25 meter-imagined gait trial. The imagined speed reserve (ISR) defined as the difference between imagined brisk and comfortable gait speeds was measured as a control of behavioral performance. Imaging data processing and analyses were performed using SPM8. The first-level individual contrast images representing the comparison between brisk and comfortable gait were entered as two separate groups (controls vs patients) in an ANOVA with the corresponding ISRs as correlation regressors. Results: Compared with controls, patients showed hypokinetic gait during real gait training as their increase in speed during brisk relatively to comfortable gait was related to an increase in step ca- dence (r50.87; p<0.001) but not in step length (r50.11). ISRs meas- ured during fMRI and their real counterparts measured offline strongly correlated in patients (r50.88; p<0.001) and controls (r50.59; p50.02). Between-group comparison (p<0.001, uncorrected) of fMRI data showed that increasing imagined gait speed was strongly associated with increased activity of the left posterior parietal cortex in controls and with decreased activity of this region in patients. Conclusions: Our findings suggest that hypokinetic gait in PD is related to the impaired functioning of the left posterior parietal cortex. This area may represent a target for therapeutic interventions aimed at alleviating gait disturbances in PD. [less ▲]

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See detailChirurgie metabolique: une place croissante dans le traitement du diabete.
De Flines, J.; Franck, M.; Rorive, M. et al

in Revue Médicale Suisse (2012), 8(351), 1621-41626-7

Bariatric surgery becomes more and more important in the management of the obese patient with type 2 diabetes, especially in case of failure of medical approaches. Metabolic improvement results not only ... [more ▼]

Bariatric surgery becomes more and more important in the management of the obese patient with type 2 diabetes, especially in case of failure of medical approaches. Metabolic improvement results not only from weight loss and the subsequent reduction in insulin resistance, but also from modifications of digestive hormones (especially incretins) that contribute to promote insulin secretion. This new paradigm, moving from bariatric surgery to metabolic surgery, opens new perspectives. The present article briefly describes innovative surgical techniques focusing on endocrine and metabolic improvement rather than on weight loss, the preliminary results of metabolic surgery in patients with type 2 diabetes and a body mass index <35 kg/m2 and, finally, some data regarding the surgical management of obese patients with type I diabetes not well treated with classical medical means. [less ▲]

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See detailMethod for the preliminary design of Piano Key Weirs
Machiels, Olivier ULg; Erpicum, Sébastien ULg; Archambeau, Pierre ULg et al

in Houille Blanche (2012), 4

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together ... [more ▼]

The Piano Key Weir (PKW) is a particular geometry of weir associating to a labyrinth shape the use of overhangs to reduce the basis length. The PKW could thus be directly placed on a dam crest. Together with its important discharge capacity for low heads, this geometric feature makes the PKW an interesting solution for dam rehabilitation. However, its hydraulic design remains problematic, even at a preliminary stage. This paper presents a preliminary design method based on results of experimental tests. The method enables to design project models by extrapolation of characteristics of existing idealized scale models. A practical application is presented to illustrate the method. [less ▲]

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See detailPrevalence and management of cancer-related anaemia, iron deficiency and the specific role of intravenous iron
Aapro, M.; Osterborg, A.; Gascon, P. et al

in Annals of Oncology (2012), 23

Background: Chronic diseases reduce the availability of iron for effective erythropoiesis. This review summarises clinical consequences of iron deficiency (ID) and anaemia in cancer patients, mechanisms ... [more ▼]

Background: Chronic diseases reduce the availability of iron for effective erythropoiesis. This review summarises clinical consequences of iron deficiency (ID) and anaemia in cancer patients, mechanisms how impaired iron homeostasis affects diagnosis and treatment of ID, and data from clinical trials evaluating i.v. iron with or without concomitant erythropoiesis-stimulating agents (ESAs). Design: Clinical trial reports were identified in PubMed and abstracts at relevant major congresses. Results: Reported prevalence of ID in cancer patients ranges from 32 to 60% and most iron-deficient patients are also anaemic. Randomised clinical trials have shown superior efficacy of i.v. iron over oral or no iron in reducing blood transfusions, increasing haemoglobin, and improving quality of life in ESA-treated anaemic cancer patients. Furthermore, i.v. iron without additional ESA should be evaluated as potential treatment in patients with chemotherapyinduced anaemia. At recommended doses, i.v. iron is well tolerated, particularly compared with oral iron. No serious drug-related adverse effects were seen during long-term use in renal disease and no effect on tumour growth has been observed in trials with anaemic cancer patients. Conclusions: Reliable diagnosis and treatment of ID are recommended key steps in modern cancer patient management to minimise impact on quality of life and performance status. [less ▲]

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See detailLes organisations d'aide et soins à domicile: des entreprises à haute valeur ajoutée
Defourny, Jacques ULg

in La Revue de l'Aide et des Soins à Domicile (2012), 131(mai-juillet), 24-27

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See detailÉtude de la cyclicité en relation avec le poids vif et l’état corporel chez les agnelles Ouled Djellal nées en automne dans la région Est de l’Algérie
Lamrani, F; Benyounes, A; Sulon, J et al

in Annales de Médecine Vétérinaire (2012), 156

The objective of the present work was to describe the cyclicity of Ouled Djellal ewes born one year before regarding their live weight and body condition score, during the autumn season. The study has ... [more ▼]

The objective of the present work was to describe the cyclicity of Ouled Djellal ewes born one year before regarding their live weight and body condition score, during the autumn season. The study has been driven in the region of Guelma, East of Algeria, on 104 ewes belonging to two farms. At the beginning of the study, ewes from farms A and B had similar ages but differed in live weight and body condition scores. The concentration of progesterone wasdetermined by radioimmunoassay. The level of spontaneous cyclicity, as well as the plasmatic level of the progesterone, were influenced significantly by both live weight and body condition score (P<0.0001). If the first was in favor of ewes with high body weight and body condition score, the second seemed to be higher in slim cyclic ewes. The body fatness appears to influence positively the age of puberty. [less ▲]

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See detailConclusions de synthèse: étendue de l'obligation de motivation du juge
Biemar, Bénédicte ULg

in Revue de Jurisprudence de Liège, Mons et Bruxelles (2012), (7), 295

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See detailErrors in 2-D modelling using a 0th order turbulence closure for compound channel flows
Linde, F.; Paquier, A.; Proust, S. et al

in International Conference on Fluvial Hydraulics, River Flow 2012 (2012)

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows ... [more ▼]

When dealing with flood issues, compound channels flows are often encountered in the field. This paper investigates the errors that can be expected when using 2-D modelling for compound channel flows, comparing the simulations with experiments. Three flow configurations are analyzed: uniform, gradually varied and rapidly varied flows. The last configuration is obtained by setting a transverse embankment on the flood plain. Errors are estimated on the sub-section mean velocity, discharge andwater depth, on the mixing layer width and on the depth-averaged stream-wise velocity and lateral shear stress. Depending on the flow configuration and on the studied parameter, relative errors significantly vary from nearly zero to 50%. The influence of the 0th order turbulence closure on the mean flow and the dimensions of the recirculation zone behind the embankment is also investigated, using either constant eddy viscosity or Elder's model. © 2012 Taylor & Francis Group, London. [less ▲]

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See detailReducing hazards for humans from animals: emerging and re-emerging zoonoses
Saegerman, Claude ULg; Dal Pozzo, Fabiana ULg; Humblet, Marie-France ULg

in Italian Journal of Public Health (2012), 9(2), 13-24

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See detailNécrologie Jacques Stiennon (1920-2012)
George, Philippe ULg

in Cahiers de Civilisation Médiévale (2012), 55

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