References of "2012"
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See detailDebt and Pension
Artige, Lionel ULg; Cavenaile, Laurent; Pestieau, Pierre ULg

Conference (2012, February 15)

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See detailNouvelles approches thérapeutiques de l’Arthrose
Kaux, Jean-François ULg

Conference (2012, February 15)

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See detailHuntington’s Disease: From the Physiological Function of Huntingtin to the Disease
Borgs, Laurence ULg; Godin, Juliette ULg; Malgrange, Brigitte ULg et al

in Huntington's Disease - Core Concepts and Current Advances (2012)

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See detailContribution à l'étude de la surveillance de la mécanique ventilatoire du nouveau-né ventilé.
RIGO, Vincent ULg

Doctoral thesis (2012)

Mechanical ventilation, still a major intervention to improve prognosis in newborns, requires careful monitoring of ventilated infants. This monitoring integrates different parameters. Its classical focus ... [more ▼]

Mechanical ventilation, still a major intervention to improve prognosis in newborns, requires careful monitoring of ventilated infants. This monitoring integrates different parameters. Its classical focus is on blood gases and their proxy (pulse oxymetry, transcutaneous oxygen and carbon dioxide content), and also includes physical assessment, thoracic imaging and appraisal of ventilator settings. Use of currently available on-line respiratory mechanics (RM) as displayed by ventilators seems limited given a large apparent variability. As current respiratory support strategies aim to reduce exposure to mechanical ventilation and to decrease ventilator associated lung injuries, additional continuous monitoring tools could benefit neonatal patients. In a review of advanced biomedical devices in use in the neonatal intensive care units and areas where improvement or evaluation is necessary, the National Institute for Child Health and Human Development underlines simple tools for continuous assessment of vital pulmonary functions at the bedside. This research aims at finding solutions to that problem. In a first step, different respiratory mechanics parameters (dynamic compliance –Cdyn, dynamic resistance –Rdyn, tidal volume –VT and the overdistension parameter C20/C) are obtained from ventilatory recordings of newborns under respiratory support with the most commonly used neonatal ventilator to evaluate their clinical relevance. Those data present a high variability and therefore lack precision. It is possible to mathematically decrease this variability by using parameters averaged over a few minutes and to obtain reproducible results. Continuous pressure, flow and volume data from the ventilator allow construction of pressure-volume, pressure-flow and flow-volume loops. From those loops, Cdyn, Rdyn and VT can be computed by the Mead-Whittenberger method. Those values when derived from respiratory cycles with good appearance significantly differ from ventilator values. Given the lack of precision of ventilator derived respiratory mechanics data, a new strategy is developed to obtain those parameters only from optimal looking respiratory cycles. A new software is designed to reconstruct waves and loops from the ventilator continuous recordings. This software individualises respiratory cycles and compute Cdyn and Rdyn (least mean square method), VT and C20/C. Using 10 sets of two recordings (one in Synchronized Intermittent Mandatory Ventilation and one in Assist/Control ventilatory modes), visual evaluation of 11274 respiratory cycles selects 4847 cycles considered optimal looking. Those assisted cycles present no or minimal leak, good hysteresis of the pressure-volume loop, and no abnormalities of the flow curves. The coefficients of variation of the respiratory mechanics parameters obtained with this method are significantly decreased, by 25-27% from the ventilator values for Rdyn, Cdyn and C20/C, and by 60% for VT. This increase in parameters precision is associated with an improved capacity to discriminate different values. Analysis of discordant values between ventilator and optimal respiratory cycles is relevant. In A/C mode, the VTs from the selected respiratory cycles are lower than values reported by the ventilator, suggesting that currently available VTs give incomplete information for adjustment of ventilator settings. In SIMV mode, the weak correlation between Cdyn from both methods leads to question the relevance of ventilator informations. The important scattering of ventilator C20/Cs out of classical values, and the absence of correlation with values from selected respiratory cycles demonstrate the lack of validity of ventilator C20/Cs. Overall, the results suggest that the use of data derived from selected respiratory cycles could underlie the conception of RM monitoring tools to support ventilatory management. To avoid the heavy workload associated with visual respiratory cycles’ selection, the software is improved to automatically identify optimal cycles. The positive predictive values and specificity of this selection are high. Respiratory mechanics parameters from cycles selected automatically are very concordant with those from visually selected cycles. The last step of this work assesses the software potential with analysis of 21 recordings from various clinical situations. The discriminating power of automatically selected respiratory cycles’ parameters is tested in an extended population. Trending abilities of those parameters are evaluated. Analyses of respiratory mechanics parameters derived from automatically selected cycles are able to demonstrate differences of 4.6-7.1% and more between parameters from two 10min recordings. Averaging data over 3-7min allows to determine a 10% difference. Parameters averaged over 10min allow detection of 10% changes in most patients. Those results should allow building trend curves with clinically and statistically significant informations. In conclusion, the continuous respiratory mechanics analysis software developed and evaluated in this work should give precise informations on the dynamic evolution of RM parameters. Functions integrated in the last version of the software give immediate research opportunities, and should lead to clinical application in a very near future. Those parameters could then complete current informations integrated in ventilatory management. [less ▲]

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See detailTheater in Originalversion. Theatertreffen vor ausverkauften Rängen.
Deleersnijder, Henri ULg; Viehöver, Vera ULg

Article for general public (2012)

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See detailL'université sous la coupe du marché ?
Bachelet, Jean-François ULg

Article for general public (2012)

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See detailComment et pourquoi faut-il rester actif pour les patients Alzheimer?
Adam, Stéphane ULg

Scientific conference (2012, February 15)

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See detailSémantique et enjeux politiques de la cité sainte kimbanguiste de Nkamba
Melice, Anne ULg

Scientific conference (2012, February 15)

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See detailHydromechanical analysis of fracturing in clayey rocks : modelling of disturbed argillite and ventilation test
Pardoen, Benoît ULg; Collin, Frédéric ULg

Scientific conference (2012, February 15)

The present advances in hydro-mechanical analysis of a clayey rock fracturing are presented at a department seminar. The damaged zone existing around galleries composing underground structures is studied ... [more ▼]

The present advances in hydro-mechanical analysis of a clayey rock fracturing are presented at a department seminar. The damaged zone existing around galleries composing underground structures is studied through two aspects: rock-atmosphere interaction at gallery wall and rock fracturing modelling. These two aspects are discussed through the numerical results of an in situ ventilation test modelling and a biaxial compression test modelling. [less ▲]

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See detailPsychologie et antipsychologisme chez Husserl – l’année 1894
Gyemant, Maria ULg

in Gyemant, Maria (Ed.) Psychologie et psychologisme (2012, February 14)

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See detailGenetic parameters for methane indicator traits based on milk fatty acids
Kandel, Purna Bhadra ULg; Gengler, Nicolas ULg; Soyeurt, Hélène ULg

Scientific conference (2012, February 14)

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See detailIdentifier et contacter un informateur
Brahy, Rachel ULg; Lejeune, Christophe ULg

Scientific conference (2012, February 14)

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Peer Reviewed
See detailFuture projections of the Greenland ice sheet climate simulated by the regional climate model MAR forced by 2 CMIP5 global models.
Fettweis, Xavier ULg; Franco, Bruno ULg

Conference (2012, February 14)

As part of the ICE2SEA project, the regional climate model MAR was forced by the global models HadCM3 and ECHAM5 for making future projections of the Greenland Ice Sheet (GrIS) Surface Mass Balance (SMB ... [more ▼]

As part of the ICE2SEA project, the regional climate model MAR was forced by the global models HadCM3 and ECHAM5 for making future projections of the Greenland Ice Sheet (GrIS) Surface Mass Balance (SMB) over 1980-2099 at a resolution of 25km. However, the comparison with MAR forced by the ERA-40 reanalysis over 1980-1999 shows that MAR forced by these GCMs is not able to represent reliably the current SMB due to biases in the general circulation and in the free atmosphere summer temperature modelled by these GCMs around the GrIS. <br /> <br /> That is why, we present here first results of MAR forced by the next generation of GCMs from the CMIP5 data base (CanESM2 and NorESM1 here). The comparison with the ERA-40 forced MAR simulations over current climate is a lot of better, which increases the reliability and the interest of these new MAR projections. In addition, the new scenarios (RCP 2.6, 4.5, 6.0 and 8.5) of the next IPCC Assessment Report (AR5) are used here. These new simulations show notably that the response of SMB to rising temperature is not a linear function of the temperature anomalies due to the positive albedo feedback which accelerates the surface melt. For 2100, in case of extreme rising temperature (RCP 8.5 scenario), MAR simulates a surface GrIS mass loss corresponding to a cumulated sea level rise of about 15 cm since 2000! Mainly the changes in SMB and in surface energy balance will be discussed here. [less ▲]

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See detailL'accélération du temps judiciaire, une comparaison France-Belgique
Schoenaers, Frédéric ULg; Bastard, Benoît

Scientific conference (2012, February 14)

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See detailLes jeunes Belges francophones et le génocide des Juifs. Les enseignements d’une perspective de socialisation politique
Grandjean, Geoffrey ULg

Doctoral thesis (2012)

La mémoire du génocide des Juifs est encore vivace dans nos sociétés contemporaines. Ce fait passé apparaît fréquemment dans l’actualité au rythme des commémorations régulièrement organisées. Mais que ... [more ▼]

La mémoire du génocide des Juifs est encore vivace dans nos sociétés contemporaines. Ce fait passé apparaît fréquemment dans l’actualité au rythme des commémorations régulièrement organisées. Mais que peut-il signifier aujourd’hui pour de jeunes générations qui en prennent connaissance à l’école, en famille, par la visite de lieux de mémoire ou encore par de multiples œuvres cinématographiques ? Les impacts de ces connaissances sont ainsi très peu étudiés, notamment en termes d’apprentissage d’attitudes et de comportements politiques chez des jeunes amenés à devenir les citoyens de demain. En s’inscrivant dans le champ de la socialisation politique, l’objectif de cette étude est justement d’analyser les conséquences de ces connaissances. Pour ce faire, de jeunes Belges francophones ont été rencontrés dans le cadre de groupes de discussion. L’analyse des échanges montre que ces jeunes ont tenu différentes expressions sociales et politiques à partir de discussions portant uniquement sur le génocide des Juifs. En soulignant l’importance du souvenir, en témoignant de multiples émotions et en mobilisant toute une série de valeurs, ils ont envisagé la transmission de ce fait passé. Par ailleurs, leurs connaissances et leurs perceptions de l’univers politique ainsi que la façon dont ils envisagent leur participation politique interrogent leur rapport au pouvoir politique. En explorant l’univers mental des jeunes à partir de la thématique du génocide des Juifs, leur prise de conscience des cheminements politiques conduisant à un tel fait est mise en perspective. C’est aussi l’éventualité de sa répétition ou encore l’effacement de sa mémoire dans la dynamique des générations qui est mis en questions et en débats. [less ▲]

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See detailInitiation à la rédaction d'une décision répressive
Michiels, Olivier ULg

Conference given outside the academic context (2012)

La note passe en revue les principales étapes de la rédaction d'une décision en matière répressive. Elle contient en outre des illustrations tirées de la pratique.

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See detailEnergie et environnement
Gautier, Axel ULg

Speech/Talk (2012)

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