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See detailRegulation of a-Synuclein Membrane Binding and Its Implications
Chen, Robert; Wislet, Sabine ULg; Mount, Howard et al

in Juliana Dushanova (Ed.) Mechanisms in Parkinson Disease models and treatment (2012)

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See detailLeptogenesis in the presence of exact flavor symmetries
Aristizabal Sierra, Diego ULg; Bazzocchi, Federica

in Journal of High Energy Physics [=JHEP] (2012)

In models with flavor symmetries in the leptonic sector leptogenesis can take place in a very different way compared to the standard leptogenesis scenario. We study the generation of a B−L asymmetry in ... [more ▼]

In models with flavor symmetries in the leptonic sector leptogenesis can take place in a very different way compared to the standard leptogenesis scenario. We study the generation of a B−L asymmetry in these kind of models in the flavor symmetric phase pointing out that successful leptogenesis requires (i) the right-handed neutrinos to lie in different irreducible representations of the flavor group; (ii) the flavons to be lighter at least that one of the right-handed neutrino representations. When these conditions are satisfied leptogenesis proceeds due to new contributions to the CP violating asymmetry and — depending on the specific model — in several stages. We demonstrate the validity of these arguments by studying in detail the generation of the B − L asymmetry in a scenario of a concrete A 4 flavor model realization. [less ▲]

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See detailGiddens et la modernité radicale
Jacquemain, Marc ULg

in Politique : Revue de Débats (2012), 74(mars-avril),

L'article examine brièvement comment la théorie de la modernité réflexive de Giddens, appliquée au domaine de l'intime et de la construction du soi, conduit à sa construction politique de la "troisième ... [more ▼]

L'article examine brièvement comment la théorie de la modernité réflexive de Giddens, appliquée au domaine de l'intime et de la construction du soi, conduit à sa construction politique de la "troisième voie". Le texte défend que, y compris pour les critiques "de gauche" de Giddens, son analyse de la modernité est utile, parce qu'elle décrit - en creux - les limites de la portée émancipatrice de la réflexivité. [less ▲]

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See detailLes secrets de l'astrolabe - suite
Nazé, Yaël ULg

Article for general public (2012)

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See detailL'identité européenne et la mondialisation - commentateur
Hermans, Michel ULg

Conference (2012, March)

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See detailStructure cordale, phonotraumatisme et lésions cordales
FINCK, Camille ULg

Conference (2012, March)

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See detailDifferential expression of Vegfr-2 and its soluble form in preeclampsia.
Munaut, Carine ULg; LORQUET, Sophie ULg; Pequeux, Christel ULg et al

in PLoS ONE (2012), 7(3), 33475

Background: Several studies have suggested that the main features of preeclampsia (PE) are consequences of endothelial dysfunction related to excess circulating anti-angiogenic factors, most notably ... [more ▼]

Background: Several studies have suggested that the main features of preeclampsia (PE) are consequences of endothelial dysfunction related to excess circulating anti-angiogenic factors, most notably, soluble sVEGFR-1 (also known as sFlt-1) and soluble endoglin (sEng), as well as to decreased PlGF. Recently, soluble VEGF type 2 receptor (sVEGFR-2) has emerged as a crucial regulator of lymphangiogenesis. To date, however, there is a paucity of information on the changes of VEGFR-2 that occur during the clinical onset of PE. Therefore, the aim of our study was to characterize the plasma levels of VEGFR-2 in PE patients and to perform VEGFR-2 immunolocalization in placenta. METHODOLOGY/PRINCIPAL FINDINGS: By ELISA, we observed that the VEGFR-2 plasma levels were reduced during PE compared with normal gestational age matched pregnancies, whereas the VEGFR-1 and Eng plasma levels were increased. The dramatic drop in the VEGFR-1 levels shortly after delivery confirmed its placental origin. In contrast, the plasma levels of Eng and VEGFR-2 decreased only moderately during the early postpartum period. An RT-PCR analysis showed that the relative levels of VEGFR-1, sVEGFR-1 and Eng mRNA were increased in the placentas of women with severe PE. The relative levels of VEGFR-2 mRNA as well as expressing cells, were similar in both groups. We also made the novel finding that a recently described alternatively spliced VEGFR-2 mRNA variant was present at lower relative levels in the preeclamptic placentas. CONCLUSIONS/SIGNIFICANCE: Our results indicate that the plasma levels of anti-angiogenic factors, particularly VEGFR-1 and VEGFR-2, behave in different ways after delivery. The rapid decrease in plasma VEGFR-1 levels appears to be a consequence of the delivery of the placenta. The persistent circulating levels of VEGFR-2 suggest a maternal endothelial origin of this peptide. The decreased VEGFR-2 plasma levels in preeclamptic women may serve as a marker of endothelial dysfunction. [less ▲]

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See detailEffect of physicochemical characteristics of cellulosic substrates on enzymatic hydrolysis by means of a multi-stage process for cellobiose production
Vanderghem, Caroline ULg; Jacquet, Nicolas ULg; Danthine, Sabine ULg et al

in Applied Biochemistry and Biotechnology (2012), 166(6), 1423-1432

The effect of two types of cellulose, microcrystalline cellulose and paper pulp, on enzymatic hydrolysis for cellobiose production was investigated. The particle size, the relative crystallinity index and ... [more ▼]

The effect of two types of cellulose, microcrystalline cellulose and paper pulp, on enzymatic hydrolysis for cellobiose production was investigated. The particle size, the relative crystallinity index and the water retention value were determined for both celluloses. A previously studied multistage hydrolysis process that proved to enhance the cellobiose production was studied with both types of celluloses. The cellobiose yield exhibited a significant improvement (120% for the microcrystalline cellulose and 75% for the paper pulp) with the multistage hydrolysis process compared to continuous hydrolysis. The conversion of cellulose to cellobiose was greater for the microcrystalline cellulose than for the paper pulp. Even with high crystallinity, microcrystalline cellulose achieved the highest cellobiose yield probably due to its highest specific surface area accessible to enzymes and quantity of adsorbed protein. [less ▲]

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See detailVers une architecture verticale. Le cas de Liège
Charlier, Sébastien ULg; Frankignoulle, Pierre ULg

in Cahiers Nouveaux (Les) (2012), 81

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See detailLe religieux et le politique en Afrique subsaharienne
Melice, Anne ULg

Scientific conference (2012, March)

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See detailLa libre circulation des personnes dans et vers l'Union européenne: année 2011
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2012), 20(187), 85-92

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See detailImproved Domain Decomposition Method for the Wave Equation in Harmonic Regime
Geuzaine, Christophe ULg; Antoine, X.; Boubendir, Y. et al

in Proceedings of the 6th Advanced Computational Electromagnetics workshop (ACE 2012) (2012, March)

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See detailL'influence de la gouvernance familiale sur la transmission de la PME familiale au Sénégal : une modélisation contingente
Van Caillie, Didier ULg; Mbili Onana,

in COMREFAS - Consortium pour le Management de la Recherche Fondamentale en Afrique au Sud du Sahara (Ed.) Actes du 1er Congrès International en Sciences de Gestion du COMREFAS (2012, March)

In Senegal, family businesses are present in all industries and represent a significant force. Most of family entrepreneurs are between 40 and 50 years old, which show that they will soon face the ... [more ▼]

In Senegal, family businesses are present in all industries and represent a significant force. Most of family entrepreneurs are between 40 and 50 years old, which show that they will soon face the challenge of transmission. To face this challenge and thus to ensure their continuity, it is necessary to ensure the cohesion of family ties, particularly through the family governance. So, our contribution aims, in a contingent perspective and based on a large survey of the existing literature, to a better appraisal of family businesses in Senegal through a better understanding of their family governance practices first, and by understanding the role of family governance on their global performance in order to identify key success factors for a successful family transmission process in the context of Senegal. [less ▲]

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See detailEffects of management regimes and extreme climatic events on plant population viability in Eryngium alpinum
Andrello, Marco; Bizoux, Jean-Philippe ULg; BARBET-MASSIN, morgane et al

in Biological Conservation (2012), 147(1), 99-106

Extreme climatic events like the 2003 summer heatwave and inappropriate land management can threaten the existence of rare plants. We studied the response of Eryngium alpinum, a vulnerable species, to ... [more ▼]

Extreme climatic events like the 2003 summer heatwave and inappropriate land management can threaten the existence of rare plants. We studied the response of Eryngium alpinum, a vulnerable species, to this extreme climatic event and different agricultural practices. A demographic study was conducted in seven field sites between 2001 and 2010. Stage-specific vital rates were used to parameterize matrix population models and perform stochastic projections to calculate population growth rates and estimate extinction probabilities. Among management regimes, spring grazing and land abandonment decreased vital rates and population growth, while autumn grazing and late mowing had positive effects on population viability. The 2003 heatwave reduced fecundity rates and survival rates. Only spring grazed sites presented considerable extinction risk. Stochastic projections showed that an increased frequency of 2003-like events may exacerbate extinction risk, but extinction probability depends mainly on land management regimes. To better conserve E. alpinum populations, we recommend conversion of presently spring grazed and abandoned sites to late mowing or autumn grazing. [less ▲]

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See detailTask 4.0 – Subsystem Optimization of the Structure Scantling
Rigo, Philippe ULg; Yerna, Olivier ULg; Amrane, Amirouche ULg

Report (2012)

In the present report concerning Task 4.0 – Subsystem Optimization of the Structure Scantling, the structural optimization of the ship is carried out. This optimization is performed with regard to the ... [more ▼]

In the present report concerning Task 4.0 – Subsystem Optimization of the Structure Scantling, the structural optimization of the ship is carried out. This optimization is performed with regard to the objective functions and the constraints defined in Deliverables 2.0 & 3.0 [1]. Task 4.0 is divided into three parts: - The initial scantling - The load cases and loadings - The optimized scantling This report presents the results and benefits of optimization. Comments and analysis are provided throughout the report. [less ▲]

Detailed reference viewed: 60 (6 ULg)