References of "2012"
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See detail"Blumenworte / Kriegsgestammel" - Rose Ausländer au Pays des Mots
Leyh, Valérie ULg

in Culture, le Magazine Culturel de l'Université de Liège (2012)

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See detailARE CAPABILITY INDICES USEFULL TO ASSESS ANALYTICAL METHODS VALIDITY ?
Rozet, Eric ULg; Bouabidi, Abderrahim ULg; Talbi, M. et al

Poster (2012, February)

Analytical methods capability evaluation can be a useful methodology to assess the fitness of purpose of these methods for their future routine application. However, care on how to compute the capability ... [more ▼]

Analytical methods capability evaluation can be a useful methodology to assess the fitness of purpose of these methods for their future routine application. However, care on how to compute the capability indices has to be made. Indeed, the commonly used formulas to compute capability indices such as Cpk, will highly overestimate the true capability of the methods. Especially during methods validation or transfer, there are only few experiments performed and, using in these situations the commonly applied capability indices to declare a method as valid or as transferable to a receiving laboratory will conduct to inadequate decisions. In this work, an improved capability index, namely Cpk-tol and the corresponding estimator of proportion of non conforming results ( ) is proposed. Through Monte-Carlo simulations, they have been shown to greatly increase the estimation of analytical methods capability in particular in low sample size situations as encountered during methods validation or transfer. Additionally, the usefulness of this capability index is illustrated through several case studies covering applications commonly encountered in the pharmaceutical industry. Finally a methodology to determine the optimal sample size required to validate analytical methods is also given using the proposed capability metric. [less ▲]

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See detailPsychomotor disadaptation syndrome: a poorly known clinical entity
lepage, stéphanie; GILLAIN, Sophie ULg; Petermans, Jean ULg

in Revue Médicale de Liège (2012), 67(2), 75-80

Le Syndrome de Désadaptation PsychoMotrice (SDPM) représente une entité clinique typiquement gériatrique. Il regroupe des troubles posturaux tels que la rétropulsion du corps, des troubles de la marche ... [more ▼]

Le Syndrome de Désadaptation PsychoMotrice (SDPM) représente une entité clinique typiquement gériatrique. Il regroupe des troubles posturaux tels que la rétropulsion du corps, des troubles de la marche peu spécifiques, des signes neurologiques comme une akinésie axiale et une hypertonie, ainsi que des troubles psychocomportementaux proches de ceux retrouvés dans la dépression. Son diagnostic repose tant sur la clinique que sur les données iconographiques. Ce syndrome cause des chutes qui occasionnent un sentiment d’insécurité chez la personne âgée. Celle-ci se dévalorise, risque de se replier sur elle-même et de perdre son autonomie et tout contact social. Dans cet article, nous évoquerons brièvement la physiopathologie, tenterons de rappeler les outils diagnostiques et proposerons une prise en charge des patients souffrant de ce syndrome. [less ▲]

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See detailThe Taoussa project (Mali): an example of effective composite modeling
Erpicum, Sébastien ULg; Dewals, Benjamin ULg; Vuillot, Jean Marie et al

in 4th IAHR International Symposium on Hydraulic Structures (2012, February)

Physical modeling and numerical modeling are two efficient analysis approaches in hydraulic engineering. The interactive application of both methods is obviously the more effective response to most flow ... [more ▼]

Physical modeling and numerical modeling are two efficient analysis approaches in hydraulic engineering. The interactive application of both methods is obviously the more effective response to most flow problems analyses. This paper presents the results of a successful application of such a composite numerical – physical study carried out by the Research Group Hydraulics in Environmental and Civil Engineering (former HACH) of the University of Liège on behalf of Coyne et Bellier (Tractebel Engineering). It concerned, at the stage of detailed draft, the hydraulic study of the Taoussa Project on the Niger River in Mali. The studies, performed in less than 6 months, focused on the flow characteristics at the scale of the reservoir and the river, using the numerical approach, as well as on hydrodynamic details in the spillway using a large scale factor physical model with boundary conditions defined on the basis of numerical modeling. [less ▲]

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See detailLe dosage des acides gras érythrocytaires : comparaison entre une population de référence et des sujets ayant présenté un infarctus aigu du myocarde
LE GOFF, Caroline ULg; Leroy, Ludovic; Kaux, Jean-François ULg et al

Poster (2012, February)

Introduction Un acide gras (AG) est un acide carboxylique avec une longue chaine aliphatique, qui peut être saturé ou insaturé. Récemment, le rôle des AG, particulièrement, celui des oméga-3 et oméga-6, a ... [more ▼]

Introduction Un acide gras (AG) est un acide carboxylique avec une longue chaine aliphatique, qui peut être saturé ou insaturé. Récemment, le rôle des AG, particulièrement, celui des oméga-3 et oméga-6, a émergé comme facteur de risque cardiovasculaire dans la littérature. Le but de ce travail était de comparer les taux d’AG mesurés dans une population saine avec ceux obtenus chez des patients admis aux urgences pour un infarctus du myocarde. Matériels et méthodes Cinquante quatre sujets sains (33±11ans, 31 femmes) ont été sélectionnés comme population de référence. Ces derniers ont été sélectionnés selon leur mode de vie (alimentation, tabac, etc). En parallèle, nous avons dosé les AG chez 33 patients (55±9 ans, 12 femmes) admis dans le service d’urgence de notre institution pour infarctus aigu du myocarde (AMI). Le sang était prélevé sur EDTA. Avant l’analyse, les échantillons étaient lavés et transméthylés. Le dosage des AG était réalisé par chromatographie gazeuse couplée à un détecteur à ionisation de flamme (GCFID). Après le dosage, nous avons réalisés une comparaison des taux, sommes et rapport entre les différents AG ainsi que l’index oméga-3 (somme de l’acide eicosapentaénoïque et docosahexaénoïque) obtenus dans les 2 groupes. Résultats. Des valeurs de référence ont été obtenues pour notre population de référence via le logiciel de statistique MedCalc. Dans le groupe AMI, les taux d’oméga-6 étaient significativement plus élevés (p<0.05) pour C18:2n6 (Figure 1) et C18:3n6 (Figure 2)comparés aux résultats obtenus dans la population de référence. Par contre les taux d’oméga-3 étaient significativement plus bas (p<0.01) par rapport aux sujets de référence pour le C22 :6n3 (Figure 3). L’index oméga-3 montrait une valeur plus basse et le rapport oméga-6/oméga-3 était plus élevé dans le groupe AMI comparé aux sujets de référence. Conclusion Le dosage des AG est un nouvel outil que le laboratoire peut proposer aux cliniciens afin de stratifier les patients présentant le plus de risque cardiovasculaire avant ou après un infarctus du myocarde. Ces patients pourraient ainsi être supplémenté en acides gras oméga-3 afin d’éviter les récidives d’infarctus du myocarde ou de diminuer la formation de la plaque d’athérosclérose avant le premier accident. [less ▲]

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See detailInvisible computer for collaborative design : evaluation of a multimodal sketch-based environment
Defays, Aurore ULg; Safin, Stéphane ULg; Darses, Françoise et al

in Work: A Journal of Prevention, Assessment and Rehabilitation (2012), Supplement 1

In the areas of design, especially in architectural design, collaboration has become an important challenge. The specialization of skills increase, work teams are more and more extensive and the ... [more ▼]

In the areas of design, especially in architectural design, collaboration has become an important challenge. The specialization of skills increase, work teams are more and more extensive and the geographic distance between them increases too. The economic and ecological stakes related to remote collaboration are an evidence. This context involves the need to support most efficiently possible remote working meetings. We present the Distributed Collaborative Digital Studio (DSDC), a tool designed to recreate, in distant situations, the context of copresence meetings. This shared environment is created in the “invisible computer” approach. The idea is that the tool should disappear from user’s consciousness. Indeed, creative design activities require some fluidity in their process. Therefore, any involuntary interruption created by the system can potentially brake creativity. In this perspective, we investigate specifically the “invisibility” of our environment. To do this, we propose a framework for the operationalization of the concept and a methodology to test the system invisibility. This methodology was applied through a case study consisting of a corpus of 12 hours of remote collaborative design sessions with the DSDC. We highlight the learning effects while using our system, conclude on its effectiveness and discuss our methodology. [less ▲]

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See detailEloge académique du professeur Charles-Léon Lapière
Angenot, Luc ULg

in Bulletin et Mémoires de l'Académie Royale de Médecine de Belgique (2012), 167(1), 21-27

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See detailPath Similarity Evaluation using Bloom Filters
Donnet, Benoît ULg; Gueye, Bamba,; Kaafar, Mohamed Ali

in Computer Networks (2012), 56(2), 858-869

The performance of several Internet applications often relies on the measurability of path similarity between different participants. In particular, the performance of content distribution networks mainly ... [more ▼]

The performance of several Internet applications often relies on the measurability of path similarity between different participants. In particular, the performance of content distribution networks mainly relies on the awareness of content sources topology information. It is commonly admitted nowadays that, in order to ensure either path redundancy or efficient content replication, topological similarities between sources is evaluated by exchanging raw traceroute data, and by a hop by hop comparison of the IP topology observed from the sources to the several hundred or thousands of destinations. In this paper, based on real data we collected, we advocate that path similarity comparisons between different Internet entities can be much simplified using lossy coding techniques, such as Bloom filters, to exchange compressed topology information. The technique we introduce to evaluate path similarity enforces both scalability and data confidentiality while maintaining a high level of accuracy. In addition, we demonstrate that our technique is scalable as it requires a small amount of active probing and is not targets dependent. [less ▲]

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See detailDeterminism in tropical forest biomass distribution due to forest spatial structure, highlighted by the study of the edge effect.
Bastin, Jean-François ULg; Bogaert, Jan; De Cannière, Charles

in Islands in land- and seascape: the challenges of fragmentation, Erlangen February 2012 (2012, February)

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See detailTwo-dimensional and M-mode echocardiographic reference values in healthy adult Saanen goats
Leroux, Aurélia ULg; Moonen, Marie ULg; Farnir, Frédéric ULg et al

in Veterinary Record : Journal of the British Veterinary Association (2012), 170(6), 154

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats. The ... [more ▼]

Echocardiography has become a routine non invasive cardiac diagnostic tool in most species. Accurate measurement of cardiac dimensions requires reference values, which are poorly documented in goats. The aim of this study was to test the inter-day repeatability and to establish the reference values of two-dimensional (2D-) and time-motion (M-) mode echocardiographic variables in healthy adult Saanen goats. Six goats were investigated three times by the same observer at one day interval using a standardized 2D- and M-mode echocardiographic protocol. The intra-observer inter-day repeatability was tested using analysis of variance, calculation of the coefficient of variation and confidence intervals. A single echocardiographic examination was performed in 6 other goats, and values obtained in the 12 goats were used to establish the 2D- and M-mode echocardiographic reference values in healthy adult female Saanen goats. Statistical analysis revealed a good inter-day repeatability of the echocardiographic cardiac measurements. Echocardiographic reference values obtained in healthy adult Saanen goats seemed slightly higher than those reported in healthy Swedish domestic goats and were similar to those reported in healthy adult sheep. [less ▲]

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See detailMultiple functional variants at the 3p21 locus contribute to ulcerative colitis: Results from a European consortium
Cleynen, I; Artieda, M; Verspaget, H et al

in Journal of Crohn’s and Colitis [=JCC] (2012)

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See detailSubproblem Approach for Thin Shell Dual Finite Element Formulations
Dang, Quoc Vuong ULg; Dular, Patrick ULg; Vazquez Sabariego, Ruth ULg et al

in IEEE Transactions on Magnetics (2012), 48(2), 407-410

A subproblem technique is applied to dual thin shell finite element formulations. Both the magnetic vector potential and magnetic field formulations are considered. The subproblem approach developed ... [more ▼]

A subproblem technique is applied to dual thin shell finite element formulations. Both the magnetic vector potential and magnetic field formulations are considered. The subproblem approach developed herein couples three problems: a simplified model with only inductors, a thin region problem using approximate interface conditions and a correction problem to improve the accuracy of the thin shell approximation, in particular near their edges and corners. Each problem has its own geometry and is solved on its associated finite element mesh. [less ▲]

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See detailF-LARSP 1.0: An Adaptation of the LARSP Language Profile for French.
Maillart, Christelle ULg; Parisse, Christophe; Tommerdahl, Jodi

in Clinical Linguistics & Phonetics (2012), 2

The LARSP (Language Assessment, Remediation and Screening Procedure) (Crystal et al., 1976) is a linguistic profile commonly used by researchers and clinicians to carry out detailed analyses of the ... [more ▼]

The LARSP (Language Assessment, Remediation and Screening Procedure) (Crystal et al., 1976) is a linguistic profile commonly used by researchers and clinicians to carry out detailed analyses of the grammar and morphology of children’s spontaneous language samples. This paper discusses the methods used to adapt the profile from English to French using a large corpus of child language in order to accurately assign morphosyntactic structures to age-based stages. [less ▲]

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See detailTowards a Dynamic Stakeholder Management framework for CSR Certifications
Abboubi, Manal; Cornet, Annie ULg

in International Journal of Business and Social Science (2012), 3(4),

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See detailRhino vs paquebot: 1-0
Hamers, Jérémy ULg

Article for general public (2012)

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See detailEvaluation of the cytotoxicity of organic dust components on thp1 monocytes-derived-macrophages using high content analysis
Ramery, Eve ULg; O'Brien, Peter James

in Environmental Toxicology (2012)

Organic dust contains pathogen-associated molecular patterns (PAMPs) which can induce significant airway diseases following chronic exposure. Mononuclear phagocytes are key protecting cells of the ... [more ▼]

Organic dust contains pathogen-associated molecular patterns (PAMPs) which can induce significant airway diseases following chronic exposure. Mononuclear phagocytes are key protecting cells of the respiratory tract. Several studies have investigated the effects of PAMPs and mainly endotoxins, on cytokine production. However the sub-lethal cytotoxicity of organic dust components on macrophages has not been tested yet. The novel technology of high content analysis (HCA) is already used to assess subclinical drug-induced toxicity. It combines the capabilities of flow cytometry, intracellular fluorescence probes, and image analysis and enables rapid multiple analyses in large numbers of samples. In the present study, HCA was used to investigate the cytotoxicity of the 3 major PAMPs contained in organic dust, ie. endotoxin (LPS), peptidoglycan (PGN) and β-glucans (zymosan) on THP-1 monocyte-derived macrophages. LPS was used at concentrations of 0.005, 0.01, 0.02, 0.05, 0.1 and 1 μg/ml; PGN and zymosan were used at concentrations of 1, 5, 10, 50, 100 and 500 μg/ml. Cells were exposed to PAMPs for 24 h. In addition, the oxidative burst and the phagocytic capabilities of the cells were tested. An overlap between PGN intrinsic fluorescence and red/far-red fluorescent dyes occurred, rendering the evaluation of some parameters impossible for PGN. LPS induced sub-lethal cytotoxicity at the lowest dose (from 50 ng/ml). However, the greatest cytotoxic changes occurred with zymosan. In addition, zymosan, but not LPS, induced phagosome maturation and oxidative burst. Given the fact that β-glucans can be up to 100-fold more concentrated in organic dust than LPS, these results suggest that β-glucans could play a major role in macrophage impairment following heavy dust exposure and will merit further investigation in the near future. [less ▲]

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See detailCyclic behaviour of cohesionless soils under seismic loading
Cerfontaine, Benjamin ULg

Diverse speeche and writing (2012)

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