References of "2012"
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See detailLa primauté de l’intentionnalité et ses conséquences philosophiques
Boccaccini, Federico ULg

Conference (2012, March)

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See detailAnalysis of tobacco mainstream smoke by GC×GC TOFMS
Brokl, Michal ULg; Bishop, Louise; Wright, Christopher et al

Poster (2012, March)

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See detailClinical Tools for A Personalized Treatment Strategy in Depression.
Desseilles, Martin ULg; Witte, Janet; Trina, E. Chang et al

in Current Psychiatry (2012), 11(3), 26-33

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See detailThe instability strip of ZZ Ceti white dwarfs I. Introduction of time-dependent convection
Van Grootel, Valérie ULg; Dupret, Marc-Antoine ULg; Fontaine, Gilles et al

in Astronomy and Astrophysics (2012), 539

Aims. The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years due to the lack of a suitable treatment for ... [more ▼]

Aims. The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years due to the lack of a suitable treatment for convection in these stars. For the first time, a full nonadiabatic approach including time-dependent convection is applied to ZZ Ceti pulsators, and we provide the appropriate details related to the inner work- ings of the driving mechanism at work. Methods. We used the nonadiabatic pulsation code MAD with a representative evolutionary sequence of a 0.6 M⊙ DA white dwarf. This sequence is made of state-of-the-art models that include a detailed modeling of the feedback of convection on the atmospheric structure. The assumed convective efficiency in these models is the so-called ML2/α = 1.0 version. We also carried out, for comparison purposes, nonadiabatic computations within the frozen convection approximation, as well as calculations based on models with standard grey atmospheres. Results. We find that pulsational driving in ZZ Ceti stars is concentrated at the base of the superficial H convection zone, but at depths, near the blue edge of the instability strip, somewhat larger than those obtained with the frozen convection approach. Despite the fact that this approach is formally invalid in such stars, particularly near the blue edge of the instability strip, the predicted boundaries are not dramatically different in both cases. The revised blue edge for a 0.6 M⊙ model is found to be around Teff = 11,970 K, some 240 K hotter than the value predicted within the frozen convection approximation, in rather good agreement with the empirical value. On the other hand, our predicted red edge temperature for the same stellar mass is only about 5600 K (80 K hotter than with the frozen convection approach), much lower than the observed value. Conclusions. We correctly understand the development of pulsational instabilities of a white dwarf as it cools at the blue edge of the ZZ Ceti instability strip. Our current implementation of time-dependent convection however still lacks important ingredients to fully account for the observed red edge of the strip. We will explore a number of possibilities in the future papers of this series. [less ▲]

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See detailArt public : entre pratiques sauvages et commandes officielles
Hagelstein, Maud ULg

in Cahiers Nouveaux (Les) (2012), 81

L’expression «art public» désigne l’ensemble des oeuvres d’art qui ont été commandées, planifiées et exécutées en vue d’être placées dans un espace public. Partant de cette définition sommaire, on ... [more ▼]

L’expression «art public» désigne l’ensemble des oeuvres d’art qui ont été commandées, planifiées et exécutées en vue d’être placées dans un espace public. Partant de cette définition sommaire, on pourrait être tenté d’établir une différence entre un art public de commande et un art public plus sauvage : d’un côté, une instance publique souhaite qu’un artiste produise une oeuvre reflétant l’état d’esprit d’un environnement urbain donné et de ses habitants ; de l’autre, les artistes font des percées intempestives dans le paysage visuel de la ville – et ce, sans qu’on leur ait rien demandé. Cette distinction servirait une stratégie sans doute grossière visant à séparer au sein de l’espace public art de convenance et art subversif. Là où les uns essaieraient de rencontrer les goûts normés du citoyen moyen, les autres prendraient au contraire le risque de la désapprobation en déstabilisant les codes en vigueur et les normes esthétiques. Mais cette opposition entre art de convenance et art subversif constitue probablement un cliché grotesque. Aussi adoptera-t-on un point de vue plus fécond en montrant plutôt les contiguïtés entre l’art de commande et de l’art sauvage. Dans un cas comme dans l’autre, dès que les oeuvres d’art sont publiques, elles posent des problèmes spécifiques. Quels que soient les objectifs qui l’animent, dès qu’il franchit les murs de l’institution, du musée ou de la galerie, l’artiste prend un risque considérable. Et au fond, que sa proposition artistique soit autorisée ou illégale, d’un certain point de vue, le risque demeure. C’est ce qu’il s’agira ici d’identifier. [less ▲]

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See detailStrontium ranelate reduces the number of radiological or radioclinical progressors in patients with primary knee osteoarthritis
Reginster, Jean-Yves ULg; Chapurlat, R; Christiansen, C et al

in Osteoporosis International (2012, March), 23(S2), 366-367

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See detailCarte hydrogéologique de Wallonie, Louveigné-Spa; 49/3-4, 1/25.000 : [notice explicative]
Ruthy, Ingrid ULg; Dassargues, Alain ULg

Book published by Service Public de Wallonie, DGARNE - Version provisoire : mars 2012 (2012)

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See detailAu-delà des limites. Focus sur quatre maisons d’édition alternatives bruxelloises
Paques, Frédéric ULg

in Lectures : La Revue des Bibliothèques (2012), 175

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See detailPilot Trial of STAR in Medical ICU
Fisk, Liam M.; Le Compte, Aaron J.; Shaw, Geoffrey M. et al

Poster (2012, March)

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See detailRELIABILITY OF ANALYTICAL METHODS’ RESULTS: A BAYESIAN APPROACH TO ANALYTICAL METHOD VALIDATION
Rozet, Eric ULg; Govaerts, B.; Lebrun, Pierre ULg et al

Conference (2012, March)

Methods validation is mandatory in order to assess the fitness of purpose of the developed analytical method. Of core importance at the end of the validation is the evaluation of the reliability of the ... [more ▼]

Methods validation is mandatory in order to assess the fitness of purpose of the developed analytical method. Of core importance at the end of the validation is the evaluation of the reliability of the individual results that will be generated during the routine application of the method. Regulatory guidelines provide a general framework to assess the validity of a method, but none address the issue of results reliability. In this study, a Bayesian approach is proposed to address this concern. Results reliability is defined here as “the probability ()π of an analytical method to provide analytical results within predefined acceptance limits ()X()λ± around their reference or conventional true concentration values ()Tμ over a defined concentration range and under given environmental and operating conditions.” By providing the minimum reliability probability (minπ needed for the subsequent routine application of the method, as well as specifications or acceptance limits ()λ±, the proposed Bayesian approach provides the effective probability of obtaining reliable future analytical results over the whole concentration range investigated. This is summarized in a single graph: the reliability profile. This Bayesian reliability profile is also compared to two frequentist approaches, the first one derived from the work of Dewé et al. [1] and the second proposed by Govaerts et al. [2]. Furthermore, the applicability of the Bayesian reliability profile is shown using as example the validation of a bioanalytical method dedicated to the determination of ketoglutaric acid (KG) and hydroxymethylfurfural (HMF) in human plasma by SPE-HPLC-UV. [1] Dewé W., Govaerts B., Boulanger B., Rozet E., Chiap P., Hubert Ph., Chemometr. Intell. Lab. Syst. 85 (2007) 262-268. [2] B. Govaerts, W. Dewé, M. Maumy, B. Boulanger, Qual. Reliab. Engng. Int. 24 (2008) 667-680. [less ▲]

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See detailQuinze ans d'anti-TNF dans la maladie de Crohn: comment tirer le meilleur de cette revolution therapeutique?
Louis, Edouard ULg; REENAERS, Catherine ULg; Meuwis, Marie-Alice ULg et al

in Revue Médicale de Liège (2012), 67 Spec No

After fifteen years of use, the anti-TNF antibodies have become the corner stone of the treatment of moderate and severe Crohn's disease. The skill acquired over the years through experimental trials and ... [more ▼]

After fifteen years of use, the anti-TNF antibodies have become the corner stone of the treatment of moderate and severe Crohn's disease. The skill acquired over the years through experimental trials and clinical experience leads to increased therapeutic efficacy and minimized risks. These antibodies are introduced increasingly earlier in Crohn's disease as well as in a broader range of patients, aiming at changing the natural history of the diseases by avoiding the development of intestinal tissue damage and complications. [less ▲]

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See detailNote de recherche n°33. La Politique de la ville
Harou, Raphaëlle; Lejeune, Zoé ULg

Report (2012)

Cette note de recherche relative à la politique de la ville en Wallonie a été réalisée dans le cadre du diagnostic territorial confié à la CPDT pour l’actualisation du Schéma de développement de l’espace ... [more ▼]

Cette note de recherche relative à la politique de la ville en Wallonie a été réalisée dans le cadre du diagnostic territorial confié à la CPDT pour l’actualisation du Schéma de développement de l’espace régional wallon en 2010-2011. Le présent document propose de revenir sur les différents aspects de la politique à destination des villes en Wallonie. Même si la Région ne dispose pas encore d’une politique spécifiquement dédiée à ses villes, elle a développé une série d’instruments qui participent à la redynamisation des zones urbaines. De plus, une réflexion a été lancée en 2011 afin de définir les grandes orientations à donner à une future politique de la ville en Wallonie. [less ▲]

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See detailStructured differential diagnosis of a transient impairment of consciousness
HANSEN, Isabelle ULg; MELON, P.; CREEMERS, Etienne ULg et al

in Revue Médicale de Liège (2012), 67(3),

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See detailStrontium ranelate and risk of venous thromboembolism (VTE) : an update of a retrospective cohort study in the UK general practice research database (GPRD)
Cooper, C; Deltour, N; Speirs, C et al

in Osteoporosis International (2012, March), 23(S2), 364-365

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See detailCarte hydrogéologique de Wallonie, Louveigné-Spa, 49/3-4
Ruthy, Ingrid ULg; Dassargues, Alain ULg

Cartographic material (2012)

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See detailVers une politique active du patrimoine dans le SDER nouveau
Fisher, Axel ULg; Goossens, Marc ULg; Occhiuto, Rita ULg et al

in Cahiers Nouveaux (Les) (2012), 81

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See detailWhat are the most important medication attributes for patients with osteoporosis ? Results from a qualitative study
Hiligsmann, Mickaël ULg; Van Durme, C; Geusens, P et al

in Osteoporosis International (2012, March), 23(S2), 81-82

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See detailCharacterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
Lambert, Cécile ULg; Mathy-Hartert, Marianne; Dubuc, JE et al

in Arthritis Research & Therapy (2012), 14(2), 58

INTRODUCTION: This work aimed at comparing the production of inflammatory and pro- and anti-angiogenic factors by normal/reactive (N/R) or inflammatory (I) areas of the osteoarthritic synovial membrane ... [more ▼]

INTRODUCTION: This work aimed at comparing the production of inflammatory and pro- and anti-angiogenic factors by normal/reactive (N/R) or inflammatory (I) areas of the osteoarthritic synovial membrane. The effects of interleukin (IL)-1β and chondroitin sulfate (CS) on the expression of pro- and anti-angiogenic factors by synovial fibroblasts cells (SFC) were also studied. METHODS: Biopsies from N/R or from I areas of osteoarthritic synovial membrane were collected at the time of surgery. The inflammatory status of the synovial membrane was characterized by the surgeon according to macroscopic criteria, including the synovial vascularization, the villi formation and the hypertrophic aspect of the tissue. We assessed the expression of CD45, von Willebrand factor and vascular endothelial growth factor (VEGF) antigen by immunohistochemistry in both N/R and I biopsies. The production of IL-6, -8, VEGF and thrombospondin (TSP)-1 by N/R or I synovial cells was quantified by ELISA. SFC were cultured in the absence or in the presence of IL-1β (1 ng/ml) and with or without CS (10, 50, 200 μg/ml). Gene expression of pro-angiogenic factors (VEGF, basic fibroblast growth factor (bFGF), nerve growth factor (NGF), matrix metalloproteinase (MMP)-2 and angiopoietin (ang)-1) and anti-angiogenic factors (vascular endothelial growth inhibitor (VEGI), TSP-1 and -2) were determined by real time RT-PCR. Production of VEGI and TSP-1 was also estimated by ELISA. RESULTS: Immunohistochemistry showed the increase of lymphocyte infiltration, vascular density and VEGF expression in I compared to N/R synovial biopsies. Synovial cells from I areas produced more IL-6, IL-8 and VEGF but less TSP-1 than cells isolated from N/R synovial biopsies. The expression of pro-angiogenic factors by SFC was stimulated by IL-1β. A time dependent regulation of the expression of anti-angiogenic factor genes was observed. IL-1β stimulated the expression of anti-angiogenic factor genes but inhibited it after 24 h. CS reversed the inhibitory effect of IL-1β on anti-angiogenic factors, VEGI and TSP-1. CONCLUSIONS: We demonstrated that synovial biopsies from I areas expressed a pro-angiogenic phenotype. IL-1β induced an imbalance between pro- and anti-angiogenic factors in SFC and CS tended to normalize this IL-1β-induced imbalance, providing a new possible mechanism of action of this drug. [less ▲]

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See detailStructure cordale, phonotraumatisme et lésions cordales
FINCK, Camille ULg

Conference (2012, March)

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