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See detailPilot Trial of STAR in Medical ICU
Fisk, Liam M.; Le Compte, Aaron J.; Shaw, Geoffrey M. et al

Poster (2012, March)

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See detailFrom direct to inverse analysis in flexible multibody dynamics
Bruls, Olivier ULg

Conference (2012, March)

Today, state-of-the-art simulation packages in flexible multibody dynamics allow the high-fidelity analysis of industrial mechanisms and machines in many application fields including robotics, automotive ... [more ▼]

Today, state-of-the-art simulation packages in flexible multibody dynamics allow the high-fidelity analysis of industrial mechanisms and machines in many application fields including robotics, automotive systems, aeronautics, deployable structures or wind turbines. The dynamic response of a given system can thus be evaluated in the time-domain for given load cases and given initial values. However, in many practical cases, the engineer does not have a precise knowledge of the mechanical design, the loading conditions and the initial state. This situation occurs for example in structural optimization, optimal control, experimental identification and health monitoring problems. The complexity of simulation codes and the computational cost of high-fidelity models are still important obstacles for the development of efficient resolution methods for these inverse problems. A current challenge is thus to elaborate simplified and more efficient modelling strategies in flexible multibody dynamics in order to enable the development of inverse analysis methods. The talk is divided into three parts. The first part provides an overview of available simulation techniques for flexible mechanisms with a particular emphasis on finite element-based approaches and time integration methods. Some illustrations are presented in the fields of deployable structures, vehicle dynamics and wind turbines. In the second part, optimization problems in flexible multibody dynamics are addressed and solved using gradient-based methods. Efficient methods for sensitivity analysis are discussed and special problems are treated such as the structural optimization of mechanical components or the numerical solution of inverse dynamics problems. The third part discusses a recently-developed Lie group approach which allows the formulation of the equations of motion of a multibody system in a parameterization-free setting. Based on this general formalism, which is characterized by an increased modularity and a reduced complexity, a large variety of Lie group solvers are foreseen not only for time integration but also for model reduction, sensitivity analysis and optimization. [less ▲]

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See detailEstimating stellar mean density through seismic inversions
Reese, Daniel ULg; Marques, J. P.; Goupil, M. J. et al

in Astronomy and Astrophysics (2012), 539(A63), 18

Determining the mass of stars is crucial both for improving stellar evolution theory and for characterising exoplanetary systems. Asteroseismology offers a promising way for estimating the stellar mean ... [more ▼]

Determining the mass of stars is crucial both for improving stellar evolution theory and for characterising exoplanetary systems. Asteroseismology offers a promising way for estimating the stellar mean density. When combined with accurate radii determinations, such as are expected from GAIA, this yields accurate stellar masses. The main difficulty is finding the best way to extract the mean density of a star from a set of observed frequencies. We seek to establish a new method for estimating the stellar mean density, which combines the simplicity of a scaling law while providing the accuracy of an inversion technique. We provide a framework in which to construct and evaluate kernel-based linear inversions that directly yield the mean density of a star. We then describe three different inversion techniques (SOLA and two scaling laws) and apply them to the Sun, several test cases and three stars, alpha Cen B, HD 49933 and HD 49385, two of which are observed by CoRoT. The SOLA (subtractive optimally localised averages) approach and the scaling law based on the surface correcting technique described by Kjeldsen et al. (2008, ApJ, 683, L175) yield comparable results that can reach an accuracy of 0.5 % and are better than scaling the large frequency separation. The reason for this is that the averaging kernels from the two first methods are comparable in quality and are better than what is obtained with the large frequency separation. It is also shown that scaling the large frequency separation is more sensitive to near-surface effects, but is much less affected by an incorrect mode identification. As a result, one can identify pulsation modes by looking for an l and n assignment which provides the best agreement between the results from the large frequency separation and those from one of the two other methods. Non-linear effects are also discussed, as is the effects of mixed modes. In particular, we show that mixed modes bring little improvement to the mean density estimates because of their poorly adapted kernels. [less ▲]

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See detailFair Trade Organizations and Social Enterprise. Social Innovation through Hybrid Organization Models
Huybrechts, Benjamin ULg

Book published by Routledge (2012)

For several decades, Fair Trade Social Enterprises (FTSEs) have set up partnerships with producer groups in the South and distributed the latter’s products through different types of channels in the North ... [more ▼]

For several decades, Fair Trade Social Enterprises (FTSEs) have set up partnerships with producer groups in the South and distributed the latter’s products through different types of channels in the North. However, while pioneers in the early years were relatively homogeneous (nonprofit organizations relying on voluntary work and selling through “worldshops”), organizational diversity has tremendously increased in recent times, including other types of legal forms, architectures, and governance models (volunteer-based, manager-based, multi-stakeholder, etc.). As a result, different categories of FTSEs now coexist in the sector with diverse missions and strategies. Since Fair Trade (FT) is a hybrid concept, entailing economic, social and political dimensions, the diversity of organizational models might reflect or enable different ways of articulating these dimensions. In other words, different organizational models might be suited for different ways of conceiving and practicing FT. Such an articulation through specific forms has been suggested by previous concepts that can be related to FT, such as cooperatives, the social economy, the solidarity economy, and, more recently, social enterprise. The latter is particularly useful as an umbrella concept that embraces the diverse types of FTSEs and accounts for their use of market mechanisms to pursue social innovation. This research first aims to explore and to structure FTSEs’ organizational diversity. For that purpose, the managers of 57 FTSEs were interviewed in four European regions: Belgium, France (Rhône-Alpes), the United Kingdom (England) and Italy (Rome). Based on the combinations of different elements of the organizational form, five categories emerge: individual FTSEs; entrepreneurial, business-form FTSEs; volunteer-based FTSEs; multi-stakeholder cooperative FTSEs; and group structures. Although certain FTSEs share features corresponding to several models, these categories seem adequate in the sense are relatively homogeneous and distinct from each other. The second question examines the factors or forces that lead FTSEs to adopt particular and diverse organizational forms. Using sociological and economic “new institutional” approaches, this book explores the influence of a number of factors on the organizational form: age, size, region, goals, activities, resources, and leaders’ profiles. From an economic standpoint, organizational diversity may be explained by the fact that FTSEs do not all produce the same types of goods when practicing FT. Thus, FTSEs will adopt the organizational form that minimizes their transaction costs in the production of particular goods. From a sociological standpoint, the analysis suggests that weak and sometimes conflicting institutional pressures explain organizational diversity. Indeed, uniformity is limited (within certain generations of FTSEs or in particular regions), although there is a dominant trend toward a stronger business orientation in the models. The third question examines how organizational actors within FTSEs experience and foster hybridity at the field level, thereby contributing to organizational diversification. Looking at six cases of FTSEs covering the different types of models, the strategic role of FTSEs is examined, as “institutional entrepreneurs” capable of influencing the environment in a way that legitimizes their own organizational model and secures their access to crucial resources. This strategic analysis allows for a more dynamic view of organizational models as “institutional bricolage”. Finally, the book ends with a number of recommendations for FT entrepreneurs on the strengths and the weaknesses of each organizational model. [less ▲]

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See detailCyclophosphamide inhibits the generation and function of CD8(+) regulatory T cells
Conteduca, Giuseppina ULg

in Human Immunology (2012), 73(3), 207-13

CD8(+) regulatory T cells (Treg) and CD4(+)CD25(+) Treg infiltrate human cancers, thus favoring tumor immune escape. Therefore, in the setting of antitumor therapeutic protocols, it is important to ... [more ▼]

CD8(+) regulatory T cells (Treg) and CD4(+)CD25(+) Treg infiltrate human cancers, thus favoring tumor immune escape. Therefore, in the setting of antitumor therapeutic protocols, it is important to associate antitumor treatment with agents that are able to inhibit Treg function. Cyclophosphamide (CY) has been demonstrated to be effective in counteracting CD4(+)CD25(+) Treg activity. Hence, we tested its inhibitory efficacy on human CD8(+) Treg. Because CY is a prodrug, 4-hydroperoxycyclophosphamide (4-HC), a derivative of CY that in aqueous solution is converted to 4-hydroxycyclophosphamide, an active metabolite of CY, was used. 4-HC significantly inhibited CD8(+) Treg generation and function but only at the higher tested concentration (0.5 μg/mL), that is, in the therapeutic range of the drug. The lower 4-HC concentration tested (0.1 μg/mL) was almost ineffective. 4-HC inhibitory effects were related to apoptosis/necrosis induction. When CD8(+)CD28(+) non-Treg were analyzed for comparative purposes, significantly lower cytotoxic rates among these cells were observed than among CD8(+) Treg, which were differentiated because they did not express the CD28 molecule. These data demonstrate that CD8(+) Treg are inhibited through cytotoxic phenomena by CY, thus supporting the use of this drug at adequate concentrations and schedules of administration as a Treg inhibitor in combinatorial chemo- or immunotherapeutic anticancer protocols. [less ▲]

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See detailFoodborne Outbreak by a Recombinant Norovirus GIIg/1 Strain in a University Hospital in Munich
Hoffmann, Dieter; Mauroy, Axel ULg; Foley, Brian et al

Poster (2012, March)

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See detailEjecta around evolved massive stars observed with Herschel
Vamvatira-Nakou, Chloi ULg; Hutsemekers, Damien ULg; Royer, P. et al

Conference (2012, March)

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See detailIntroduction à la Renaissance italienne
Warnauts, Samuelle ULg

Conference given outside the academic context (2012)

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See detail3D thermo-elastic distortion measurements on OSIRIS SiC hardware by holographic interferometry and correlation with finite element models
Thizy, Cédric ULg; Eliot, Fabienne; Ballhause, Dirk et al

Conference (2012, March)

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See detailLe système électoral comme institutionnalisation et contrôle du conflit en démocratie
Bouhon, Frédéric ULg

Scientific conference (2012, March)

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See detailOud word je niet alleen. Een enquête over eenzaamheid en sociaal isolement bij ouderen in België
Vandenbroucke, S; Lebrun, JM; Vermeulen, B et al

Report (2012)

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See detailMass Spectrometry lab activities in Liege - Small molecules
Focant, Jean-François ULg

Scientific conference (2012, March)

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See detailNonlinear Modal Analysis of the SmallSat Spacecraft
Renson, Ludovic ULg; Noël, Jean-Philippe ULg; Kerschen, Gaëtan ULg et al

in Proceedings of the European Conference on Spacecraft Structures, Materials & Environmental Testing (2012, March)

Non-linear elements are present in practically all spacecraft structures. When such non-linear effects are important linear modal analysis can no longer be applied. The development of a non-linear ... [more ▼]

Non-linear elements are present in practically all spacecraft structures. When such non-linear effects are important linear modal analysis can no longer be applied. The development of a non-linear analogue of linear modal analysis is therefore an important endeavor. The objective of this paper is to show that nonlinear normal modes (NNMs) represent a useful and practical tool in this context. A full-scale spacecraft structure is considered and is modeled using the finite element method. Its NNMs are computed using advanced numerical algorithms, and the resulting dynamics is then carefully analyzed. Nonlinear phenomena with no linear counterpart including nonlinear modal interactions are also highlighted. [less ▲]

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See detailLa lettre des Scipions adressée à la cité de Colophon (190-189a)
Famerie, Etienne ULg

Conference (2012, March)

Un riche dossier du Fonds Louis Robert conservé à l’Académie des Inscriptions et Belles-Lettres (copies, photographies, estampages, correspondance entre De Sanctis et Holleaux) éclaire l’histoire confuse ... [more ▼]

Un riche dossier du Fonds Louis Robert conservé à l’Académie des Inscriptions et Belles-Lettres (copies, photographies, estampages, correspondance entre De Sanctis et Holleaux) éclaire l’histoire confuse des éditions de cette lettre des Scipions (RDGE, 36). Le dossier permet aussi de donner une édition revue, qui n’est pas sans incidence sur le texte d’une autre lettre des deux frères (RDGE, 35). [less ▲]

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See detailLa libre circulation des personnes dans et vers l'Union européenne: année 2011
Carlier, Jean-Yves ULg

in Journal de Droit Européen [=JDE] (2012), 20(187), 85-92

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See detailSport (and Exercise) Pedagogy and its interest in the fields of PE teaching, sport coaching and physical activity/health
Cloes, Marc ULg

Conference (2012, March)

Within the specialist seminar, the aims of this presentation were to share a personal conception of Sport (& Exercise) Pedagogy, to illustrate some current challenges for researchers of this specific ... [more ▼]

Within the specialist seminar, the aims of this presentation were to share a personal conception of Sport (& Exercise) Pedagogy, to illustrate some current challenges for researchers of this specific field of Sport Sciences, and to suggest some approaches to develop in the future. In the first part, an emphasis will be set on the analysis of the papers presented during the ARIS' congresses. It will be the opportunity to bridge the gap between Anglo-Saxon authors and those from the French speaking world, in order to underline the existence of a research corpus that is unknown by those who are not able to read another language than English. [less ▲]

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See detailNeurophysiological indices of top-down attentional processing in minimally conscious patients : an ERP study.
Schnakers, C.; Lovstad, M.; Boly, M. et al

Conference (2012, March)

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