References of "2012"
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See detailLe Parlement Jeunesse de la Communauté française, une initiative citoyenne ?
Wintgens, Sophie ULg; Dabée, Maëlle

in Fournier, Bernard; Hudon, Raymond (Eds.) Engagements politiques et citoyens de jeunes. Bilans et expériences au Canada et en Europe (2012, February)

Créée en 1997 dans l'esprit du modèle québécois, l'ASBL Parlement Jeunesse de la Communauté française organise annuellement une simulation parlementaire à destination de jeunes francophones résidants en ... [more ▼]

Créée en 1997 dans l'esprit du modèle québécois, l'ASBL Parlement Jeunesse de la Communauté française organise annuellement une simulation parlementaire à destination de jeunes francophones résidants en Belgique, âgés de 17 à 26 ans. Cette initiative citoyenne permet ainsi à une centaine de jeunes, idéalement issus de tous milieux et de tous horizons, de découvrir les rouages internes de la démocratie, conformément aux mécanismes et procédures propres au système parlementaire belge. Là où nombre d'études scientifiques sur l'engagement politique des jeunes s'accordent sur la prévalence d'un désintérêt manifeste et – plus largement – sur une tendance générale au déclin de l'engagement politique chez les jeunes, l'action citoyenne mise en œuvre par le Parlement Jeunesse témoigne en réalité de l'existence de formes moins classiques – dans le cas présent, associative – de socialisation des jeunes à la « chose politique ». L’objectif général poursuivi dans cette contribution est d'identifier la nature et les fondements de l'engagement politique déployé à travers cette jeune initiative, ainsi que d’en mesurer la portée et les limites. Dès lors, en quoi le Parlement Jeunesse participe-t-il de l’engagement politique des jeunes ? Ne contribue-t-il qu’au renforcement d’un intérêt politique latent et préexistant ? A contrario, participe-t-il de la construction d’un engagement politique au départ d’un processus d’apprentissage pratique des rouages de la démocratie parlementaire ? En d’autres termes, quelles sont les forces et les faiblesses de cette initiative citoyenne en terme de socialisation politique de la jeunesse ? [less ▲]

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See detailIMPROVE SHIP DESIGN COMPLEXITY (EASYSHIP)
Hage, André ULg; Rigo, Philippe ULg; Caprace, Jean-David ULg

Report (2012)

Nowadays productibility has become a major design attribute for shipbuilding industry. If a ship cannot be manufactured or assembled efficiently, it is not properly designed. To increase the ... [more ▼]

Nowadays productibility has become a major design attribute for shipbuilding industry. If a ship cannot be manufactured or assembled efficiently, it is not properly designed. To increase the productibility of ships, the scientific community and shipyards has developed the concept of Design For Production (DFP) which can be defined as "Design to reduce production costs to a minimum, compatible with the requirements of the vessel to fulfil its operational functions with acceptable safety, reliability and efficiency". DFP optimises all the manufacturing functions (fabrication, assembly, test, procurement, delivery, service, repair, etc.) that reduce the production work content while still meeting the specified design requirements and quality. The goal is to include the impact of design decisions on the production process. Time pressures on commercial ship contracts result in the overlapping of phases of design development, procurement and production. This makes the impact of engineering changes more difficult to manage. There is a need to systematically study the detail design process and its impact on construction with the objective to improve the process and its integration with construction. DFP can significantly reduce the costs, since ships can be quickly assembled from fewer parts. Thus, ships are easier to build and assemble, in less time, with better quality. Designers will save time and money by the reduction of the production complexity. [less ▲]

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See detailLa monnaie de sa pièce. Poétique et morale du macairisme dans les Physiologies
Stienon, Valérie ULg

in Fix, Florence; Fougère, Marie-Ange (Eds.) L’argent et le rire, de Balzac à Mirbeau (2012)

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See detailDossier Texas - Alan Govenar
Sacré, Robert ULg

Article for general public (2012)

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See detailResults of kidney transplantation from controlled donors after cardio-circulatory death: a single center experience.
Ledinh, H.; WEEKERS, Laurent ULg; BONVOISIN, Catherine ULg et al

in Transplant International (2012), 25

The aim of this study was to determine results of kidney transplantation (KT) from controlled donation after cardio-circulatory death (DCD). Primary end-points were graft and patient survival, and post ... [more ▼]

The aim of this study was to determine results of kidney transplantation (KT) from controlled donation after cardio-circulatory death (DCD). Primary end-points were graft and patient survival, and post-transplant complications. The influence of delayed graft function (DGF) on graft survival and DGF risk factors were analyzed as secondary end-points. This is a retrospective mono-center review of a consecutive series of 59 DCD-KT performed between 2005 and 2010. Overall graft survival was 96.6%, 94.6%, and 90.7% at 3 months, 1 and 3 years, respectively. Main cause of graft loss was patient's death with a functioning graft. No primary nonfunction grafts. Renal graft function was suboptimal at hospital discharge, but nearly normalized at 3 months. DGF was observed in 45.6% of all DCD-KT. DGF significantly increased postoperative length of hospitalization, but had no deleterious impact on graft function or survival. Donor body mass index >/=30 was the only donor factor that was found to significantly increase the risk of DGF (P < 0.05). Despite a higher rate of DGF, controlled DCD-KT offers a valuable contribution to the pool of deceased donor kidney grafts, with comparable mid-term results to those procured after brain death. [less ▲]

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See detailJames McAuley
Delrez, Marc ULg

Article for general public (2012)

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See detailDoes pupil constriction under blue and green monochromatic light exposure change with age?
Daneault, V; Vandewalle, Gilles ULg; Hébert, M et al

Poster (2012, February)

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See detailDifferential proteomic analysis of a human breast tumor and its matched bone metastasis identifies cell membrane and extracellular proteins associated with bone metastasis
Dumont, Bruno ULg; Castronovo, Vincenzo ULg; Peulen, Olivier ULg et al

in Journal of Proteome Research (2012)

The classical fate of metastasizing breast cancer cells is to seed and form secondary colonies in bones. The molecules closely associated with these processes are predominantly present at the cell surface ... [more ▼]

The classical fate of metastasizing breast cancer cells is to seed and form secondary colonies in bones. The molecules closely associated with these processes are predominantly present at the cell surface and in the extracellular space, establishing the first contacts with the target tissue. In this study, we had the rare opportunity to analyze a bone metastatic lesion and its corresponding breast primary tumor obtained simultaneously from the same patient. Using mass spectrometry, we undertook a proteomic study on cell surface and extracellular protein-enriched material. We provide a repertoire of significantly modulated proteins, some with yet unknown roles in the bone metastatic process as well as proteins notably involved in cancer cell invasiveness and in bone metabolism. The comparison of these clinical data with those previously obtained using a human osteotropic breast cancer cell line highlighted an overlapping group of proteins. Certain differentially expressed proteins are validated in the present study using immunohistochemistry on a retrospective collection of breast tumors and matched bone metastases. Our exclusive set of selected proteins supports the set-up of further investigations on both clinical samples and experimental bone metastasis models that will help to reveal the finely coordinated expression of proteins that favor the development of metastases in the bone microenvironment. [less ▲]

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See detailMicroorganisms from aphid honeydew attract natural enemies and tending ants
Verheggen, François ULg; Leroy, Pascal; Fischer, Christophe ULg et al

Conference (2012, February)

Aphids are some of the most serious pests of cultivated crops worldwide, causing major yield and economic losses. Previous works have demonstrated ants and natural enemies (including ladybeetles and ... [more ▼]

Aphids are some of the most serious pests of cultivated crops worldwide, causing major yield and economic losses. Previous works have demonstrated ants and natural enemies (including ladybeetles and hoverflies) to be able to use aphid volatile chemicals to locate aphid colonies. Here, we report the first isolation of a bacterium from the pea aphid Acyrthosiphon pisum honeydew, Staphylococcus sciuri, which produces kairomones used by the aphidophagous hoverfly Episyrphus balteatus and the Asian Ladybeetle Harmonia axyridis during their search for prey colonies. Some specific semiochemicals produced by S. sciuri were identified as attractants and ovipositional stimulants. Similarly, we have shown scouts of the aphid tending ant species, Lasius niger, to orientate their foraging behaviour toward an Aphis fabae infested plant and we have demonstrated that the odours released by this aphid honeydew were attractive for ant scouts. Again, bacteria were involved in the production of these honeydew semiochemicals. Interestingly, ant scouts were also able to discriminate honeydew odour from A. fabae (usually attended by L. niger) and A. pisum (unattendedby L. niger). Comparison of the volatile and bacteria composition of both aphid species honeydew were attended. [less ▲]

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See detailDaljit Nagra: Sourires de tigre et dents brunes
Munos, Delphine ULg

Article for general public (2012)

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See detailLes carrières professionnelles des cadres : regard croisé du genre et de l'âge
Grodent, Françoise ULg

Scientific conference (2012, February)

Ce papier a pour objectif de réaliser une revue de littérature qui doit permettre de construire une recherche empirique visant à apporter une vision comparative des carrières des hommes et des femmes ... [more ▼]

Ce papier a pour objectif de réaliser une revue de littérature qui doit permettre de construire une recherche empirique visant à apporter une vision comparative des carrières des hommes et des femmes cadres en regard de trois groupes d’âge : les moins de 35 ans, les [35-50] ans et les plus de 50 ans. Nous considérons les deux sexes étant donné que les trajectoires professionnelles sont influencées par le sexe de la personne ainsi que par les stéréotypes et les rôles qui y sont directement associés (genre). Les générations, quant à elles, nous permettront de tenir compte de l’évolution des facteurs de contexte que sont notamment ces rôles attribués au masculin et au féminin à travers les époques. En effet, les constructions sociales liées au sexe des individus sont susceptibles de changer d’une génération à l’autre et donc d’agir distinctement sur les intentions de carrière. Le fait d’introduire la dimension générationnelle, en plus de celle du genre, est l’occasion d’aborder le concept d’intersectionnalité qui consiste en un croisement des groupes cibles propres à la gestion de la diversité. A l’issue de cet aperçu théorique faisant état de la littérature existante relative à cette thématique des carrières des individus occupant un poste à responsabilités, nous pourrons mettre en évidence différentes questions de recherche qu’il nous faudra, dans un second temps, confronter à la réalité du terrain. [less ▲]

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See detailQUALITY BY DESIGN COMPLIANT METHOD VALIDATION
Rozet, Eric ULg; Boulanger, B.; Hubert, Philippe ULg

Poster (2012, February)

Analytical method validation is a mandatory step to evaluate the ability of developed methods to provide accurate results for their routine application in order to trust the critical decisions that will ... [more ▼]

Analytical method validation is a mandatory step to evaluate the ability of developed methods to provide accurate results for their routine application in order to trust the critical decisions that will be made with them. Even if several guidelines exist to help perform analytical method validations (ICH Q2R1 [1], USP <1225> [2], …) there is still the need to clarify the meaning and interpretation of analytical method validation criteria and methodology. Indeed, actually method validation is mostly realised as the traditional check list implementation of e.g. the ICH Q2R1 or USP <1225> method validation requirements. However, within the trend of Quality by Design [3], there is the need to switch from this traditional vision to an analytical method validation really adding value and providing a high level of assurance of analytical methods results reliability. Yet, different interpretations can be made of the validation guidelines as well as for the definitions of the validation criteria. This will lead to diverse experimental designs implemented to try fulfilling these criteria. Finally, different decision methodologies can also be interpreted from these guidelines. Therefore, the risk that a validated analytical method may be unfit for its future purpose will depend on a personal interpretation of these guidelines. The objective of this presentation is thus to show that analytical method validation should be planned and performed by first starting with the end in mind: what is the objective of the analytical methods under study? In such a way analytical method validation is coherent with the actual Quality by Design regulatory expectations. The risk of having validated an analytical method unfit for its purpose is strongly reduced as well as the risk of generating Out of Specification (OOS) results due to an unfit method. References [1] International Conference on Harmonisation (ICH) of Technical Requirements for registration of Pharmaceuticals for Human Use, Topic Q2 (R1): Validation of Analytical Procedures: Text and Methodology, Geneva, 2005. [2] USP 33 NF 28 S1, U.S. Pharmacopeia, 2007. USP–NF General Chapter <1225>. [3] International Conference on Harmonisation (ICH) of Technical Requirements for Registration of Pharmaceuticals for Human Use, Topic Q8(R2): Pharmaceutical development, Geneva, 2009. [less ▲]

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See detailEddy Currents and Corner Singularities
Buret, François; Dauge, Monique; Dular, Patrick ULg et al

in IEEE Transactions on Magnetics (2012), 48(2), 679-682

Eddy current problems are addressed in a bidimensional setting where the conducting medium is non-magnetic and has a corner singularity. For any fixed parameter linked to the skin depth for a plane ... [more ▼]

Eddy current problems are addressed in a bidimensional setting where the conducting medium is non-magnetic and has a corner singularity. For any fixed parameter linked to the skin depth for a plane interface, we show that the flux density is bounded near the corner unlike the perfect conducting case. Then as goes to zero, the first two terms of a multiscale expansion of the magnetic potential are introduced to tackle the magneto-harmonic problem. The heuristics of the method are given and numerical computations illustrate the obtained accuracy. [less ▲]

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See detailRapport 2 FIRST Spin Off IMONIC
Goffin, Dorothée ULg

Report (2012)

Rapport du projet FIRST spin-off IMONIC financé par le SPW (Production de mélanges à valeur santé contenant des isomaltooligosaccharides et de l’acide gluconique prébiotiques et répondant au cahier des ... [more ▼]

Rapport du projet FIRST spin-off IMONIC financé par le SPW (Production de mélanges à valeur santé contenant des isomaltooligosaccharides et de l’acide gluconique prébiotiques et répondant au cahier des charges de l’agriculture biologique). [less ▲]

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See detailRutherford backscattering analysis of porous thin TiO2 films
Mayer, Matej; von Toussaint, Udo; Dewalque, Jennifer ULg et al

in Nuclear Instruments & Methods in Physics Research. Section B, Beam Interactions with Materials and Atoms (2012), 273

The additional energy spread due to sample porosity was implemented in the SIMNRA simulation code, version 6.60 and higher. Deviations of the path length and energy loss distributions from the ones ... [more ▼]

The additional energy spread due to sample porosity was implemented in the SIMNRA simulation code, version 6.60 and higher. Deviations of the path length and energy loss distributions from the ones expected from a Poisson distribution of the number of traversed pores are taken into account. These deviations are due to the interaction of pores at higher pore concentrations by overlap or blocking. The skewnesses of the energy distributions are approximated by two-piece normal distributions with identical first three moments. Propagation of porosity-induced energy spread in thick layers is taken into account. Calculated results are compared to experimental data obtained with thin TiO2 mesoporous films measured by Rutherford backscattering (RBS),transmission electron microscopy (TEM), and atmospheric poroellipsometry. [less ▲]

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See detailOn different types of adjustment usable to calculate the parameters of the stream power law
Demoulin, Alain ULg; Beckers, Arnaud ULg; Bovy, Benoît ULg

in Geomorphology (2012), 138(1), 203-208

Model parameterization through adjustment to field data is a crucial step in the modeling and the understanding of the drainage network response to tectonic or climatic perturbations. Using as a test case ... [more ▼]

Model parameterization through adjustment to field data is a crucial step in the modeling and the understanding of the drainage network response to tectonic or climatic perturbations. Using as a test case a data set of 18 knickpoints that materialize the migration of a 0.7-Ma-old erosion wave in the Ourthe catchment of northern Ardennes (western Europe), we explore the impact of various data fitting on the calibration of the stream power model of river incision, from which a simple knickpoint celerity equation is derived. Our results show that statistical least squares adjustments (or misfit functions) based either on the streamwise distances between observed and modeled knickpoint positions at time t or on differences between observed and modeled time at the actual knickpoint locations yield significantly different values for the m and K parameters of the model. As there is no physical reason to prefer one of these approaches, an intermediate least-rectangles adjustment might at first glance appear as the best compromise. However, the statistics of the analysis of 200 sets of synthetic knickpoints generated in the Ourthe catchment indicate that the timebased adjustment is the most capable of getting close to the true parameter values. Moreover, this fitting method leads in all cases to an m value lower than that obtained from the classical distance adjustment (for example, 0.75 against 0.86 for the real case of the Ourthe catchment), corresponding to an increase in the non-linear character of the dependence of knickpoint celerity on discharge [less ▲]

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See detailBio-ORACLE: a global environmental dataset for marine species distribution modelling
Tyberghein, Lennert; Verbruggen, Heroen; Klaas, Pauly et al

in Global Ecology & Biogeography (2012), 21(2), 272-281

Detailed reference viewed: 31 (1 ULg)