References of "2012"
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See detailHome range size and daily path length in a wild troop of northern pigtailed macaques (Macaca leonina): preliminary results
Jose Dominguez, Juan Manuel; Albert, aurélie; Garcia, CJ et al

Conference (2012, March)

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See detailFair Trade Organizations and Social Enterprise. Social Innovation through Hybrid Organization Models
Huybrechts, Benjamin ULiege

Book published by Routledge (2012)

For several decades, Fair Trade Social Enterprises (FTSEs) have set up partnerships with producer groups in the South and distributed the latter’s products through different types of channels in the North ... [more ▼]

For several decades, Fair Trade Social Enterprises (FTSEs) have set up partnerships with producer groups in the South and distributed the latter’s products through different types of channels in the North. However, while pioneers in the early years were relatively homogeneous (nonprofit organizations relying on voluntary work and selling through “worldshops”), organizational diversity has tremendously increased in recent times, including other types of legal forms, architectures, and governance models (volunteer-based, manager-based, multi-stakeholder, etc.). As a result, different categories of FTSEs now coexist in the sector with diverse missions and strategies. Since Fair Trade (FT) is a hybrid concept, entailing economic, social and political dimensions, the diversity of organizational models might reflect or enable different ways of articulating these dimensions. In other words, different organizational models might be suited for different ways of conceiving and practicing FT. Such an articulation through specific forms has been suggested by previous concepts that can be related to FT, such as cooperatives, the social economy, the solidarity economy, and, more recently, social enterprise. The latter is particularly useful as an umbrella concept that embraces the diverse types of FTSEs and accounts for their use of market mechanisms to pursue social innovation. This research first aims to explore and to structure FTSEs’ organizational diversity. For that purpose, the managers of 57 FTSEs were interviewed in four European regions: Belgium, France (Rhône-Alpes), the United Kingdom (England) and Italy (Rome). Based on the combinations of different elements of the organizational form, five categories emerge: individual FTSEs; entrepreneurial, business-form FTSEs; volunteer-based FTSEs; multi-stakeholder cooperative FTSEs; and group structures. Although certain FTSEs share features corresponding to several models, these categories seem adequate in the sense are relatively homogeneous and distinct from each other. The second question examines the factors or forces that lead FTSEs to adopt particular and diverse organizational forms. Using sociological and economic “new institutional” approaches, this book explores the influence of a number of factors on the organizational form: age, size, region, goals, activities, resources, and leaders’ profiles. From an economic standpoint, organizational diversity may be explained by the fact that FTSEs do not all produce the same types of goods when practicing FT. Thus, FTSEs will adopt the organizational form that minimizes their transaction costs in the production of particular goods. From a sociological standpoint, the analysis suggests that weak and sometimes conflicting institutional pressures explain organizational diversity. Indeed, uniformity is limited (within certain generations of FTSEs or in particular regions), although there is a dominant trend toward a stronger business orientation in the models. The third question examines how organizational actors within FTSEs experience and foster hybridity at the field level, thereby contributing to organizational diversification. Looking at six cases of FTSEs covering the different types of models, the strategic role of FTSEs is examined, as “institutional entrepreneurs” capable of influencing the environment in a way that legitimizes their own organizational model and secures their access to crucial resources. This strategic analysis allows for a more dynamic view of organizational models as “institutional bricolage”. Finally, the book ends with a number of recommendations for FT entrepreneurs on the strengths and the weaknesses of each organizational model. [less ▲]

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See detailCharacterization of synovial angiogenesis in osteoarthritis patients and its modulation by chondroitin sulfate
Lambert, Cécile ULiege; Mathy-Hartert, Marianne; Dubuc, JE et al

in Arthritis Research & Therapy (2012), 14(2), 58

INTRODUCTION: This work aimed at comparing the production of inflammatory and pro- and anti-angiogenic factors by normal/reactive (N/R) or inflammatory (I) areas of the osteoarthritic synovial membrane ... [more ▼]

INTRODUCTION: This work aimed at comparing the production of inflammatory and pro- and anti-angiogenic factors by normal/reactive (N/R) or inflammatory (I) areas of the osteoarthritic synovial membrane. The effects of interleukin (IL)-1β and chondroitin sulfate (CS) on the expression of pro- and anti-angiogenic factors by synovial fibroblasts cells (SFC) were also studied. METHODS: Biopsies from N/R or from I areas of osteoarthritic synovial membrane were collected at the time of surgery. The inflammatory status of the synovial membrane was characterized by the surgeon according to macroscopic criteria, including the synovial vascularization, the villi formation and the hypertrophic aspect of the tissue. We assessed the expression of CD45, von Willebrand factor and vascular endothelial growth factor (VEGF) antigen by immunohistochemistry in both N/R and I biopsies. The production of IL-6, -8, VEGF and thrombospondin (TSP)-1 by N/R or I synovial cells was quantified by ELISA. SFC were cultured in the absence or in the presence of IL-1β (1 ng/ml) and with or without CS (10, 50, 200 μg/ml). Gene expression of pro-angiogenic factors (VEGF, basic fibroblast growth factor (bFGF), nerve growth factor (NGF), matrix metalloproteinase (MMP)-2 and angiopoietin (ang)-1) and anti-angiogenic factors (vascular endothelial growth inhibitor (VEGI), TSP-1 and -2) were determined by real time RT-PCR. Production of VEGI and TSP-1 was also estimated by ELISA. RESULTS: Immunohistochemistry showed the increase of lymphocyte infiltration, vascular density and VEGF expression in I compared to N/R synovial biopsies. Synovial cells from I areas produced more IL-6, IL-8 and VEGF but less TSP-1 than cells isolated from N/R synovial biopsies. The expression of pro-angiogenic factors by SFC was stimulated by IL-1β. A time dependent regulation of the expression of anti-angiogenic factor genes was observed. IL-1β stimulated the expression of anti-angiogenic factor genes but inhibited it after 24 h. CS reversed the inhibitory effect of IL-1β on anti-angiogenic factors, VEGI and TSP-1. CONCLUSIONS: We demonstrated that synovial biopsies from I areas expressed a pro-angiogenic phenotype. IL-1β induced an imbalance between pro- and anti-angiogenic factors in SFC and CS tended to normalize this IL-1β-induced imbalance, providing a new possible mechanism of action of this drug. [less ▲]

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See detailEvaluating COSMO’s lake module (FLake) for an East-African lake using a comprehensive set of lake temperature profiles
Thiery, Wim; Martynov, Andrey; Darchambeau, François ULiege et al

Poster (2012, March)

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See detailDelayed puberty in a girl due to an inactivating mutation of the LH receptor
FUDVOYE, Julie ULiege; PARENT, Anne-Simone ULiege; Bourguignon, Jean-Pierre ULiege

Poster (2012, March)

We report the case of a 46 XY patient with a disorder of sex differentiation (DSD) caused by an inactivating mutation of the LH receptor. Mutations of genes involved in hypothalamic-pituitary-gonadal ... [more ▼]

We report the case of a 46 XY patient with a disorder of sex differentiation (DSD) caused by an inactivating mutation of the LH receptor. Mutations of genes involved in hypothalamic-pituitary-gonadal function are rare but they provide an experience of nature for understanding the physiology and the pathophysiology of gonadotropins actions. There arise from correlation between the phenotypes and genotypes in those unique conditions. Management of this particular patient with no LH activity involves oestrogen replacement therapy to induce breast development together with a gonadectomy due to the risk of gonadoblastoma in streak gonads. [less ▲]

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See detailAN INNOVATIVE APPROACH TO SELECT THE PREDICTION MODEL IN THE DEVELOPMENT OF NIR SPECTROSCOPIC METHODS
Ziemons, Eric ULiege; Mantanus, Jérôme ULiege; Rozet, Eric ULiege et al

Poster (2012, March)

Taking into account its non-invasive, non-destructive character and fast data acquisition, near infrared spectroscopy is more and more integrated in production processes to acquire analytical results ... [more ▼]

Taking into account its non-invasive, non-destructive character and fast data acquisition, near infrared spectroscopy is more and more integrated in production processes to acquire analytical results. Implementation of a NIR quantitative method is performed using an iterative heuristic approach that will ultimately build a model allowing the prediction of the concentration of the analyte of interest. In this context, the aim of the present study was to develop an innovative approach based on statistical tolerance intervals and the desirability index FMI (Fitting Model Index) to select the most appropriate prediction model from a list of candidate models instead of using conventional criteria such as R², RMSEC, RMSECV and RMSEP [1-2] without objective decision rules. This new approach is illustrated on different steps of a real pharmaceutical manufacturing process: water and Active Pharmaceutical Ingredient (API) determinations in pharmaceutical pellets. Variability sources such as production campaigns, batches, days and operators were introduced in the calibration and validation sets. Partial Least Square (PLS) regression on the calibration sets was performed to build prediction models of which the ability to quantify accurately was tested with the validation sets. Regarding the product specifications, the acceptance limits were set at 20% and 5%, for the moisture and API determination, respectively.As can be seen from Figure 1 and 2, this innovative approach based on the desirability index FMI of the accuracy profile enabled to build and select the most appropriate prediction model in full accordance with its very final goal, to quantify as accurately as possible the analytes of interest. [1] Hubert Ph. et al., J. Pharm. Biomed. Anal., 36, 2007, 579-586. [2] Rozet E. et al., Ana. Chim. Acta, 591, 2007, 239-247. [less ▲]

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See detailClinical significance of Escherichia albertii
Ooka, Tadasuke; Seto, Kazuko; Linden, Annick ULiege et al

in Emerging Infectious Diseases (2012), 18(3), 488-492

Discriminating Escherichia albertii from other Enterobacteriaceae is diffi cult. Systematic analyses showed that E. albertii represents a substantial portion of strains currently identifi ed as eae ... [more ▼]

Discriminating Escherichia albertii from other Enterobacteriaceae is diffi cult. Systematic analyses showed that E. albertii represents a substantial portion of strains currently identifi ed as eae-positive Escherichia coli and includes Shiga toxin 2f–producing strains. Because E. albertii possesses the eae gene, many strains might have been misidentifi ed as enterohemorrhagic or enteropathogenic E. coli. [less ▲]

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See detailSome Applications of Mathematical Statistics in Management
Heuchenne, Cédric ULiege

Scientific conference (2012, March)

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See detailL’Inventaire Systémique de Qualité de vie pour Adolescents (ISQV-A) : qualités psychométriques et application clinique
Etienne, Anne-Marie ULiege; Missotten, Pierre ULiege; Dupuis, Gilles

in Revue Francophone de Clinique Comportementale et Cognitive (2012), XVII(1), 44-56

Purpose: The objective was to determine the psychometric properties and the clinical application of a new Quality of Life self-assessment questionnaire suitable for adolescents 13 to 18 years old: the ... [more ▼]

Purpose: The objective was to determine the psychometric properties and the clinical application of a new Quality of Life self-assessment questionnaire suitable for adolescents 13 to 18 years old: the “Inventaire Systémique de Qualité de vie pour Adolescents” (ISQV-A). Methods: This was a cross-sectional validation study. 171 French adolescents have completed the ISQV-A. Other tools were used: the State-Trait Anxiety Inventory for Children (STAIC), the Children’s Depression Inventory (CDI). Results: The internal consistency of the four indices of the ISQV-A (state, goal, rank and gap) is satisfactory. All scores have their own specificity. The data show the convergent validity, test-retest fidelity and applicability of the ISQV-A. Conclusions: The adequacy of this new tool seems evident to highlight the adolescent’s quality of life. We will also discuss its clinical relevance into a cognitive behavioural approach. [less ▲]

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See detailIndirect comparison of bazedoxifene vs. oral bisphosphonates for the prevention of nonvertebral fractures in high-risk postmenopausal osteoporosis population
Ellis, A; Jansen, J; Luo, X et al

in Osteoporosis International (2012, March), 23(S2), 64-65

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See detailL’Inventaire Systémique de Qualité de Vie pour Personnes Agées (ISQV-65+©) : premiers éléments de validation
Missotten, Pierre ULiege; Ylieff, Michel ULiege; Etienne, Anne-Marie ULiege et al

in Revue Francophone de Clinique Comportementale et Cognitive (2012), XVII(1), 69-82

This article discusses the measurement of quality of life for old people through the preliminary validation study (applicability, reliability and validity) of a questionnaire specifically designed for ... [more ▼]

This article discusses the measurement of quality of life for old people through the preliminary validation study (applicability, reliability and validity) of a questionnaire specifically designed for this population: the Quality of Life Systemic Inventory for old people (QLSI-65+©). This validation is based on a sample of 54 non-institutionalized adults aged 65 to 85 years. All completed a sociodemographic and medical questionnaire, the QLSI-65+©, the Geriatric Depression Scale (GDS) and the Satisfaction with Life Scale (SWLS). The results show a good applicability of the QLSI-65+©. The internal consistency of the indices (State, Goal, Rank and Gap) is very satisfactory. All indices are correlated each other to varying degrees (reliability). Correlations between State, Goal and Gap QLSI-65+© global scores and GDS and SWLS total scores are significant (convergent validity). Finally, State, Goal and Gap QLSI-65+© global scores of the sample are significantly better than those of 17 informal caregivers of people with dementia (validity in terms of know group differences). [less ▲]

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See detailSeverity of incident vertebral fracture and future fracture risk: a 3-year prospective study
Bruyère, Olivier ULiege; Roux, Christian; Nicolet, Delphine ULiege et al

in Osteoporosis International (2012, March), 23(Suppl. 2), 60-61

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See detailUne approche modulaire d’évaluation de la qualité de vie en oncologie pédiatrique : les versions française et portugaise de l’Inventaire Systémique de Qualité de Vie pour Enfants (ISQV-E©)
Missotten, Pierre ULiege; Fonseca, Marta; Dupuis, Gilles et al

in Revue Francophone de Clinique Comportementale et Cognitive (2012), XVII(1), 15-33

This study approaches the question of quality of life measure in paediatric oncology. The main aim is to compare the quality of life level of children (8-12 years) undergoing (T) and off (HT) oncological ... [more ▼]

This study approaches the question of quality of life measure in paediatric oncology. The main aim is to compare the quality of life level of children (8-12 years) undergoing (T) and off (HT) oncological treatments by using the French and the Portuguese modular versions of the Child Quality of Life Systemic Inventory (QLSI-C©). The Portuguese sample consists of 26 children T and 14 HT while the Belgian sample includes 20 children T and 35 HT. Results demonstrate statistically significant differences between the T and HT groups, particularly for the French version of the QLSI-C©. They also give evidence of the influence of some clinical and sociodemographic variables on the global quality of life score, mainly for the Portuguese version of the QLSI-C©. In conclusion, findings demonstrate the clinical interest of French and Portuguese versions of the QLSI-C© and their capacity to distinguish children undergoing oncological treatments from children off these treatments. [less ▲]

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See detailFreedom, Memory, and Identity: The Paradoxical Individual/Collective Dialectic in Steve Darnall and Alex Ross’s Graphic Novel 'Uncle Sam'
Dony, Christophe ULiege

Conference (2012, March)

As his star-spangled costume and his usually firm posturing suggest, Uncle Sam impersonates the United States and symbolically reflects the nation’s most cherished values and ideals such as freedom ... [more ▼]

As his star-spangled costume and his usually firm posturing suggest, Uncle Sam impersonates the United States and symbolically reflects the nation’s most cherished values and ideals such as freedom, exceptionalism, and (masculine) strength. As such, he connects the projects of nationalism and patriotism with the scale of the individual. In other words, he embodies the American motto ‘out of many, one.’ Steve Darnall and Alex Ross’s rewriting of the character, however, strongly contrast with this dominant perception of Uncle Sam in their eponymous 1997 graphic novel. Their narrative shows a distressed and lunatic homeless man wandering the streets of an unknown American city. As he roams the streets, he undergoes an identity crisis that coincides with a crisis of memory, both of which complicate the relation between the symbolic individual body and the collective American unconscious. On the one hand, the character represents the values of freedom and democracy that the US government has strived to implement. On the other, he realizes that the paradigm of the nation cannot be understood as a monolithic entity, and that the plurality of voices that inhabit his persona – and, quite paradoxically, the country – cannot uphold this meta-narrative of American unity. In asking whether or not Uncle Sam is one of U.S., Darnall and Ross comment on the paradoxes of freedom and the myth of the melting pot. [less ▲]

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See detailLe religieux et le politique en Afrique subsaharienne
Melice, Anne ULiege

Scientific conference (2012, March)

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See detailImproved Domain Decomposition Method for the Wave Equation in Harmonic Regime
Geuzaine, Christophe ULiege; Antoine, X.; Boubendir, Y. et al

in Proceedings of the 6th Advanced Computational Electromagnetics workshop (ACE 2012) (2012, March)

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See detailTask 4.0 – Subsystem Optimization of the Structure Scantling
Rigo, Philippe ULiege; Yerna, Olivier ULiege; Amrane, Amirouche ULiege

Report (2012)

In the present report concerning Task 4.0 – Subsystem Optimization of the Structure Scantling, the structural optimization of the ship is carried out. This optimization is performed with regard to the ... [more ▼]

In the present report concerning Task 4.0 – Subsystem Optimization of the Structure Scantling, the structural optimization of the ship is carried out. This optimization is performed with regard to the objective functions and the constraints defined in Deliverables 2.0 & 3.0 [1]. Task 4.0 is divided into three parts: - The initial scantling - The load cases and loadings - The optimized scantling This report presents the results and benefits of optimization. Comments and analysis are provided throughout the report. [less ▲]

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See detailLogiques de la translation. Corps-mouvement et objets-personnages dans les films des studios Pixar
Tomasovic, Dick ULiege

in Vertigo : Revue semestrielle d'Esthétique et d'Histoire du Cinéma (2012), n°42(Printemps), 66-74

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