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See detailStrontium ranelate uncouples bone formation from bone resorption in male osteoporotic patients
COLLETTE, Julien ULg; Reginster, Jean-Yves ULg

in Osteoporosis International (2012, March), 23(S2), 365-366

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See detailL’Inventaire Systémique de Qualité de Vie pour Personnes Agées (ISQV-65+©) : premiers éléments de validation
Missotten, Pierre ULg; Ylieff, Michel ULg; Etienne, Anne-Marie ULg et al

in Revue Francophone de Clinique Comportementale et Cognitive (2012), XVII(1), 69-82

This article discusses the measurement of quality of life for old people through the preliminary validation study (applicability, reliability and validity) of a questionnaire specifically designed for ... [more ▼]

This article discusses the measurement of quality of life for old people through the preliminary validation study (applicability, reliability and validity) of a questionnaire specifically designed for this population: the Quality of Life Systemic Inventory for old people (QLSI-65+©). This validation is based on a sample of 54 non-institutionalized adults aged 65 to 85 years. All completed a sociodemographic and medical questionnaire, the QLSI-65+©, the Geriatric Depression Scale (GDS) and the Satisfaction with Life Scale (SWLS). The results show a good applicability of the QLSI-65+©. The internal consistency of the indices (State, Goal, Rank and Gap) is very satisfactory. All indices are correlated each other to varying degrees (reliability). Correlations between State, Goal and Gap QLSI-65+© global scores and GDS and SWLS total scores are significant (convergent validity). Finally, State, Goal and Gap QLSI-65+© global scores of the sample are significantly better than those of 17 informal caregivers of people with dementia (validity in terms of know group differences). [less ▲]

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See detailSeverity of incident vertebral fracture and future fracture risk: a 3-year prospective study
Bruyère, Olivier ULg; Roux, Christian; Nicolet, Delphine ULg et al

in Osteoporosis International (2012, March), 23(Suppl. 2), 60-61

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See detailAnalysis of tobacco mainstream smoke by GC×GC TOFMS
Brokl, Michal ULg; Bishop, Louise; Wright, Christopher et al

Poster (2012, March)

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See detailUn pôle d'excellence wallon en santé articulaire.
Henrotin, Yves ULg

Article for general public (2012)

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See detailThe instability strip of ZZ Ceti white dwarfs I. Introduction of time-dependent convection
Van Grootel, Valérie ULg; Dupret, Marc-Antoine ULg; Fontaine, Gilles et al

in Astronomy and Astrophysics (2012), 539

Aims. The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years due to the lack of a suitable treatment for ... [more ▼]

Aims. The determination of the location of the theoretical ZZ Ceti instability strip in the log g − Teff diagram has remained a challenge over the years due to the lack of a suitable treatment for convection in these stars. For the first time, a full nonadiabatic approach including time-dependent convection is applied to ZZ Ceti pulsators, and we provide the appropriate details related to the inner work- ings of the driving mechanism at work. Methods. We used the nonadiabatic pulsation code MAD with a representative evolutionary sequence of a 0.6 M⊙ DA white dwarf. This sequence is made of state-of-the-art models that include a detailed modeling of the feedback of convection on the atmospheric structure. The assumed convective efficiency in these models is the so-called ML2/α = 1.0 version. We also carried out, for comparison purposes, nonadiabatic computations within the frozen convection approximation, as well as calculations based on models with standard grey atmospheres. Results. We find that pulsational driving in ZZ Ceti stars is concentrated at the base of the superficial H convection zone, but at depths, near the blue edge of the instability strip, somewhat larger than those obtained with the frozen convection approach. Despite the fact that this approach is formally invalid in such stars, particularly near the blue edge of the instability strip, the predicted boundaries are not dramatically different in both cases. The revised blue edge for a 0.6 M⊙ model is found to be around Teff = 11,970 K, some 240 K hotter than the value predicted within the frozen convection approximation, in rather good agreement with the empirical value. On the other hand, our predicted red edge temperature for the same stellar mass is only about 5600 K (80 K hotter than with the frozen convection approach), much lower than the observed value. Conclusions. We correctly understand the development of pulsational instabilities of a white dwarf as it cools at the blue edge of the ZZ Ceti instability strip. Our current implementation of time-dependent convection however still lacks important ingredients to fully account for the observed red edge of the strip. We will explore a number of possibilities in the future papers of this series. [less ▲]

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See detailStrontium ranelate reduces the number of radiological or radioclinical progressors in patients with primary knee osteoarthritis
Reginster, Jean-Yves ULg; Chapurlat, R; Christiansen, C et al

in Osteoporosis International (2012, March), 23(S2), 366-367

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See detailAu-delà des limites. Focus sur quatre maisons d’édition alternatives bruxelloises
Paques, Frédéric ULg

in Lectures : La Revue des Bibliothèques (2012), 175

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See detailRELIABILITY OF ANALYTICAL METHODS’ RESULTS: A BAYESIAN APPROACH TO ANALYTICAL METHOD VALIDATION
Rozet, Eric ULg; Govaerts, B.; Lebrun, Pierre ULg et al

Conference (2012, March)

Methods validation is mandatory in order to assess the fitness of purpose of the developed analytical method. Of core importance at the end of the validation is the evaluation of the reliability of the ... [more ▼]

Methods validation is mandatory in order to assess the fitness of purpose of the developed analytical method. Of core importance at the end of the validation is the evaluation of the reliability of the individual results that will be generated during the routine application of the method. Regulatory guidelines provide a general framework to assess the validity of a method, but none address the issue of results reliability. In this study, a Bayesian approach is proposed to address this concern. Results reliability is defined here as “the probability ()π of an analytical method to provide analytical results within predefined acceptance limits ()X()λ± around their reference or conventional true concentration values ()Tμ over a defined concentration range and under given environmental and operating conditions.” By providing the minimum reliability probability (minπ needed for the subsequent routine application of the method, as well as specifications or acceptance limits ()λ±, the proposed Bayesian approach provides the effective probability of obtaining reliable future analytical results over the whole concentration range investigated. This is summarized in a single graph: the reliability profile. This Bayesian reliability profile is also compared to two frequentist approaches, the first one derived from the work of Dewé et al. [1] and the second proposed by Govaerts et al. [2]. Furthermore, the applicability of the Bayesian reliability profile is shown using as example the validation of a bioanalytical method dedicated to the determination of ketoglutaric acid (KG) and hydroxymethylfurfural (HMF) in human plasma by SPE-HPLC-UV. [1] Dewé W., Govaerts B., Boulanger B., Rozet E., Chiap P., Hubert Ph., Chemometr. Intell. Lab. Syst. 85 (2007) 262-268. [2] B. Govaerts, W. Dewé, M. Maumy, B. Boulanger, Qual. Reliab. Engng. Int. 24 (2008) 667-680. [less ▲]

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See detailL'influence de la gouvernance familiale sur la transmission de la PME familiale au Sénégal : une modélisation contingente
Van Caillie, Didier ULg; Mbili Onana,

in COMREFAS - Consortium pour le Management de la Recherche Fondamentale en Afrique au Sud du Sahara (Ed.) Actes du 1er Congrès International en Sciences de Gestion du COMREFAS (2012, March)

In Senegal, family businesses are present in all industries and represent a significant force. Most of family entrepreneurs are between 40 and 50 years old, which show that they will soon face the ... [more ▼]

In Senegal, family businesses are present in all industries and represent a significant force. Most of family entrepreneurs are between 40 and 50 years old, which show that they will soon face the challenge of transmission. To face this challenge and thus to ensure their continuity, it is necessary to ensure the cohesion of family ties, particularly through the family governance. So, our contribution aims, in a contingent perspective and based on a large survey of the existing literature, to a better appraisal of family businesses in Senegal through a better understanding of their family governance practices first, and by understanding the role of family governance on their global performance in order to identify key success factors for a successful family transmission process in the context of Senegal. [less ▲]

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See detailStrontium ranelate and risk of venous thromboembolism (VTE) : an update of a retrospective cohort study in the UK general practice research database (GPRD)
Cooper, C; Deltour, N; Speirs, C et al

in Osteoporosis International (2012, March), 23(S2), 364-365

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See detailVers une politique active du patrimoine dans le SDER nouveau
Fisher, Axel ULg; Goossens, Marc ULg; Occhiuto, Rita ULg et al

in Cahiers Nouveaux (Les) (2012), 81

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See detailUne approche modulaire d’évaluation de la qualité de vie en oncologie pédiatrique : les versions française et portugaise de l’Inventaire Systémique de Qualité de Vie pour Enfants (ISQV-E©)
Missotten, Pierre ULg; Fonseca, Marta; Dupuis, Gilles et al

in Revue Francophone de Clinique Comportementale et Cognitive (2012), XVII(1), 15-33

This study approaches the question of quality of life measure in paediatric oncology. The main aim is to compare the quality of life level of children (8-12 years) undergoing (T) and off (HT) oncological ... [more ▼]

This study approaches the question of quality of life measure in paediatric oncology. The main aim is to compare the quality of life level of children (8-12 years) undergoing (T) and off (HT) oncological treatments by using the French and the Portuguese modular versions of the Child Quality of Life Systemic Inventory (QLSI-C©). The Portuguese sample consists of 26 children T and 14 HT while the Belgian sample includes 20 children T and 35 HT. Results demonstrate statistically significant differences between the T and HT groups, particularly for the French version of the QLSI-C©. They also give evidence of the influence of some clinical and sociodemographic variables on the global quality of life score, mainly for the Portuguese version of the QLSI-C©. In conclusion, findings demonstrate the clinical interest of French and Portuguese versions of the QLSI-C© and their capacity to distinguish children undergoing oncological treatments from children off these treatments. [less ▲]

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See detailWhat are the most important medication attributes for patients with osteoporosis ? Results from a qualitative study
Hiligsmann, Mickaël ULg; Van Durme, C; Geusens, P et al

in Osteoporosis International (2012, March), 23(S2), 81-82

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See detailEffect of collagen hydrolysate in articular pain: A 6-month randomized, double-blind, placebo controlled study
Bruyère, Olivier ULg; Zegels, Brigitte ULg; LEONORI, Lorenzo ULg et al

in Osteoporosis International (2012, March), 23(Suppl. 2), 362-363

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See detailPerception, knowledge and use by general practitioners of Belgium of the FRAX tool
Bruyère, Olivier ULg; Nicolet, Delphine ULg; Compère, Stéphanie et al

in Osteoporosis International (2012, March), 23(Suppl. 2), 363-364

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