References of "2012"
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See detailPierres à aiguiser en Gaule Belgique et en Germanie : mise en place d'une typologie et identification des matériaux
Thiebaux, Aurélie ULiege; GOEMAERE, Eric; Henrotay, Denis et al

Poster (2012, April 04)

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See detailContribution of high mass resolution and accuracy of FTMS to molecular imaging
Debois, Delphine ULiege; Calligaris, David ULiege; Cimino, Jonathan ULiege et al

Conference (2012, April 04)

Since its first implementation in 1997, MALDI Mass Spectrometry Imaging (MALDI MSI) has become an important tool in the proteomic arsenal, especially for biomarker hunting. First dedicated to high ... [more ▼]

Since its first implementation in 1997, MALDI Mass Spectrometry Imaging (MALDI MSI) has become an important tool in the proteomic arsenal, especially for biomarker hunting. First dedicated to high molecular weight, MALDI MSI is more and more used to map the distribution of small molecules too (lipids, drugs and metabolites,…). Last developments tend to improve the sample treatments to obtain the best spatial resolution as possible. From this perspective, great efforts have been made on the MALDI matrix deposition methods. Now, one of the remaining challenges for MALDI-MSI users consists of identification of detected molecules. For high molecular weight, methods inspired by classical proteomics techniques, are regularly used. Bottom-Up (PMF obtained after in situ trypsin digestion) and Top-Down (in situ In-Source Decay) approaches have been used directly from a tissue slice, leading to the identification of some of the most abundant proteins present at the surface of the tissue. When small molecules are analyzed, the identification is more straightforward. Indeed, tandem mass spectrometry can easily be used, leading to the fragmentation of the detected compounds which allows their unambiguous identification. This identification is even more reliable when high resolution exact mass measurements can be performed. In this talk, I will present how in our lab, we profit of the exceptional features of FT-ICR mass spectrometry for imaging and especially for identification purposes. The first example will deal with the benefit of high mass accuracy and high mass resolution for ISD-based protein identification. The mass accuracy and high mass resolution coupled with the use of a “cleaning” software allow unequivocal assignment of ISD fragments of proteins, in the low mass range (m/z between 300 and 900), whether from pure solutions or from tissue slices. The next examples will deal with the imaging of small molecules. The identification of drugs and their metabolites is facilitated with high mass accuracy. In our lab, we work on the localization of methadone and its first metabolite, EDDP in necrophagous fly larvae. In the mass range of these compounds (278-310 m/z), many matrix ion peaks are detected and the unique features of FT-ICR allows for unambiguous identification thanks to exact mass measurements. We also use MALDI Imaging to map the messenger molecules between plant roots and beneficial bacteria. The comparison of spectra recorded with a TOF/TOF instrument and with a FT-ICR demonstrates that high resolution allows for detecting molecules which could have been missed otherwise. It also allows to distinguish unknown compounds from alkali adducts of known molecules. [less ▲]

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See detailCn. Octavius (cos. 165) dans un nouveau sénatus-consulte découvert à Volos ?
Famerie, Etienne ULiege

Scientific conference (2012, April 04)

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See detailVoir/savoir. Le partage du sensible
Havelange, Carl ULiege

Conference (2012, April 04)

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See detailCALCIUM HYDROXIDE LOADED PLGA MICROSPHERES FOR ENDODONTICS: EFFECT OF FORMULATION METHOD ON Ca++ RELEASE PROFILE
Chavarria Bolanos, Daniel ULiege; Cerda-Cristerna, BI; Flores-Reyes, Hector et al

Poster (2012, April 04)

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See detailGus Van Sant. Le cinéma en bohème
Tomasovic, Dick ULiege

Scientific conference (2012, April 04)

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See detailTrusting the source as far as it can be trusted: al-Maqrīzī and the Mongol book of laws (Yāsah)
Bauden, Frédéric ULiege

Scientific conference (2012, April 03)

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See detailÉduCoP case study: the Community of Practice of learners in Educational Sciences at the University of Liège.
Denis, Brigitte ULiege; Bomgart, Marie-Laure ULiege

in Hodgson; Jones, C; de Laat, J (Eds.) et al Proceedings of the Eighth International Conference on Networked Learning 2012 (2012, April 03)

The concept of Community of Practice (CoP) takes nowadays a great part in the formal or informal learning domain. In addition, computerised tools are often used to sustain the activities of these ... [more ▼]

The concept of Community of Practice (CoP) takes nowadays a great part in the formal or informal learning domain. In addition, computerised tools are often used to sustain the activities of these communities (Wenger, White & Smith, 2009). The ÉduCoP case study deals with the creation and the animation process of a CoP that was launched in 2010 at the University of Liège. Initiated by a master student in educational sciences, it aims at developing and making durable a community of practice composed of learners in this field and supported by Information and Communication Technologies. This paper presents several actions undertaken to develop this CoP: the analysis of the potential members' needs, stakes and motivations of students to enrol in this project; the choice of useful and usable technological tools to provide them (here, the eGroupWare platform) and the training sessions linked to its efficient uses; the activities conducted to develop the CoP's members identity and to lead them to debate about common topics, to produce and share resources. The CoP's evolution was observed through qualitative and quantitative data collection processes (e.g. interviews about the members' implication and roles, support from animator, obstacles, feeling to belong to a CoP, analysis of the topics presented in the posted documents and messages, uses of the technological tools, frequency of connection...). The results are discussed here and perspectives are evoked for this CoP. If the actions undertaken show encouraging results, neverthless obstacles to the creation and the evolution of such a CoP have been identified (e.g. lack of technological culture among some members, reluctance to share personal productions). Some perspectives are considered to overcome these problems. Since October 2011, this initiative has been recognised at the institutional level: the university is interested in lessons learned in order to implement CoP into other faculties that would be willing to start networking and create communities of learners or of practice. [less ▲]

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See detailLa querelle territoriale entre Samos et Priène : réponse à une invitation au débat
Famerie, Etienne ULiege

Scientific conference (2012, April 03)

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See detail"The Other Half of the Sun": Ideology in Chimamanda Ngozi Adichie's Half of a Yellow Sun
Tunca, Daria ULiege

Conference (2012, April 03)

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See detailNanotechnologies. Qu'est devenu le principe de précaution?
Thoreau, François ULiege; Feltz, Bernard

Article for general public (2012)

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See detailSimuler la ressource forestière à l'échelle d'un massif : application de SIMMEM et GYMNOS
Ligot, Gauthier ULiege; Vallet, Patrick; Perin, Jérôme ULiege et al

Conference (2012, April 02)

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See detailQuels modes de gouvernance pour la PMI tunisienne? Les enseignements de la littérature
Ghorbel, Jihene ULiege; Van Caillie, Didier ULiege

Conference (2012, April 02)

Les Petites et Moyennes Entreprises (PME), et tout particulièrement les Petites et Moyennes Industries (PMI), constituent un des piliers de l’économie tunisienne. Néanmoins, malgré l’abondance des études ... [more ▼]

Les Petites et Moyennes Entreprises (PME), et tout particulièrement les Petites et Moyennes Industries (PMI), constituent un des piliers de l’économie tunisienne. Néanmoins, malgré l’abondance des études consacrées aux PME dans le monde, rares sont les recherches scientifiques qui portent sur les spécificités des PME industrielles dans ce contexte géographique donné. Simultanément, face au phénomène de mondialisation croissante de l'économie et aux crises économiques et financières qui marquent la vie économique mondiale en cette première décennie du nouveau millénaire, un consensus émerge dans la littérature conduisant au constat que les PME et les PMI doivent impérativement renforcer et améliorer à la fois leurs systèmes de contrôle et de gouvernance si elles veulent jouer un rôle majeur dans leur tissu économique respectif et si elles souhaitent consolider leur crédibilité auprès de l'ensemble de leurs partenaires externes (banquiers, Pouvoirs Publics, organes de contrôle externes, ...). Notre contribution se propose dès lors, à partir d’une analyse de la littérature relativement limitée spécifique à l'objet de recherche particulier que constitue la PMI tunisienne, de mettre en évidence les spécificités de la PMI tunisienne et ses conséquences sur le design d'un système de gouvernance qui permettrait d'asseoir leur crédibilité et donc leur assise dans le paysage économique tunisien. [less ▲]

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See detailLes dysphasies : sémiologie et hypothèses explicatives
Maillart, Christelle ULiege

Conference given outside the academic context (2012)

Detailed reference viewed: 148 (13 ULiège)