References of "2012"
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See detailLiterary mediations, imaginaries and sociological approaches
Saint-Amand, Denis ULg; Glinoer, Anthony

Conference (2012, March 16)

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See detailInteractions of apamin with pore mutated SK3 channels
Dilly, Sébastien ULg; Lamy, Cédric; Poncin, Sylvie et al

Poster (2012, March 16)

In the present work, we have tested the impact of the replacement of valine residues in the pore region of SK3 (520) by either an alanine or a phenylalanine residue in terms of the interactions of apamin ... [more ▼]

In the present work, we have tested the impact of the replacement of valine residues in the pore region of SK3 (520) by either an alanine or a phenylalanine residue in terms of the interactions of apamin with these mutants in comparison with the corresponding native channels. Replacing valine residue at position 520 of the SK3 channel by a phenylalanine significantly increased the sensitivity of the channel to be blocked by tetraethylammonium (TEA) as previously reported. Indeed, an aromatic residue, such as a phenylalanine or a tyrosine, is frequently found in the pore region of several potassium channels more sensitive to TEA than SK channels. We measured the affinity (Kd) of apamin in saturation experiments and studied SK currents in transfected cells using patch clamp techniques. In parallel, molecular modelling techniques were used to examine the impact of these local modifications on the interaction of apamin with the corresponding channels. The presence of a phenylalanine in the pore region of potassium channels led to a higher sensitivity for TEA by creating more hydrophobic interactions as found by the docking procedure. In the in vitro binding experiments, the phenylalanine mutant (SK3VF) displayed a very low affinity for apamin. In patch clamp experiments, the SK current was only very partially blocked by apamin in the SK3VF mutant. Furthermore, apamin displayed an affinity and a blocking activity for the alanine mutant close to that for the corresponding native channels. In conclusion, the presence of a bulky and hydrophobic residue at a position near the pore mouth of SK3 channels has a negative impact on their interactions with apamin. [less ▲]

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See detailLes aspects nutritionnels de la betterave fourragère et son intégration dans les rations
Beckers, Yves ULg

Conference given outside the academic context (2012)

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See detailLA FALSIFICATION DES MEDICAMENTS
Marini Djang'Eing'A, Roland ULg

in Forum Pharmaceutique (2012, March 16), -(-), 16

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See detailSurface-initiated controlled radical polymerization from silica nanoparticles with high initiator density
Chakkalakal, G. Louis; Alexandre, Michaël ULg; Abetz, Clarissa et al

in Macromolecular Chemistry and Physics (2012), 213(5), 513-528

The surface of silica nanoparticles is modified using the “grafting from” technique. A multi-step reaction is conducted to modify their surface properties. (3-glycidoxypropyl) trimethoxysilane (GPS) is ... [more ▼]

The surface of silica nanoparticles is modified using the “grafting from” technique. A multi-step reaction is conducted to modify their surface properties. (3-glycidoxypropyl) trimethoxysilane (GPS) is used as the coupling agent for the fixation of atom transfer radical polymerization (ATRP) initiator. The grafting efficiency of GPS mixed with aqueous suspension of silica nanoparticles is studied, followed by the coupling efficiency towards ATRP initiator. The bromide concentration of ATRP initiator is kept constant for comparative kinetic studies of styrene and MMA polymerizations. The consequences at high conversions and the particle size distribution are studied. The behaviour of the glass transition temperature of either polymer-modified particles and the nature of dispersion of polymer-coated silica particles are analyzed. [less ▲]

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See detailA splice site variant in the bovine RNF11 gene compromises growth and regulation of the inflammatory response.
Sartelet, Arnaud ULg; Druet, Tom ULg; Michaux, Charles ULg et al

in PLoS Genetics (2012), 15(3), 1002581

We herein report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle. By resequencing positional candidates, we identify the ... [more ▼]

We herein report association mapping of a locus on bovine chromosome 3 that underlies a Mendelian form of stunted growth in Belgian Blue Cattle. By resequencing positional candidates, we identify the causative c124-2A>G splice variant in intron 1 of the RNF11 gene, for which all affected animals are homozygous. We make the remarkable observation that 26% of healthy Belgian Blue animals carry the corresponding variant. We demonstrate in a prospective study design that approximately one third of homozygous mutants die prematurely with major inflammatory lesions, hence explaining the rarity of growth-stunted animals despite the high frequency of carriers. We provide preliminary evidence that heterozygous advantage for an as of yet unidentified phenotype may have caused a selective sweep accounting for the high frequency of the RNF11 c124-2A>G mutation in Belgian Blue Cattle. [less ▲]

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See detailComplex Risks from Old Urban Waste Landfills: Sustainability Perspective from Iasi, Romania
Ciumasu, I.; Costica, M.; Costica, N. et al

in Journal of Hazardous Materials (2012), 16

Landfills continue to represent the most frequent managerial practice for municipal solid wastes and an increasing and complex problem globally. In certain countries, a transition to an open society and ... [more ▼]

Landfills continue to represent the most frequent managerial practice for municipal solid wastes and an increasing and complex problem globally. In certain countries, a transition to an open society and free market is superimposed on the transition to sustainability, resulting in even higher complexity of management. This paper proposes an approach for problem-structuring of landfills in complex transitions: sustainability or unsustainability of a management approach is determined by a set of sustainability filters that are defined by sets of indicators and prioritized according the systemic concept of sustainability, which says that economy is embedded in society, which is embedded in nature. The writers exercise this approach with an old landfill in Iasi, Romania, and conclude for unsustainability, because the ecological sustainability filter is not successfully passed. Social and economic sustainability filters are also discussed in relation with the ecological sustainability indicators. The described approach allows a coherent, transdisciplinary synthesis of knowledge scattered across various disciplines, a pervasive problem in landfill management. The case study helps distinguish between generally true and context-dependent aspects. [less ▲]

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See detailThe polyphony of public funding instruments in science and innovation policy
Fallon, Catherine ULg

Scientific conference (2012, March 15)

During the last decennia, the Walloon region in Belgium has launched new instruments to strategically fund university research. A new program called "Poles of Competitiveness" supports collaborative ... [more ▼]

During the last decennia, the Walloon region in Belgium has launched new instruments to strategically fund university research. A new program called "Poles of Competitiveness" supports collaborative research between industry and universities (Fallon & Delvenne 2010). Public funds support public-private partnerships between firms and universities. These new instruments interfere with established forms of distributed governance: industry partners are called upon to take the lead in the strategic management of large research programs and universities entered rapidly the game, while the regional administration are put on the side. Based on field research (Fallon 2011), the paper will discuss the impact of this transformation on the spaces of interactions between the actors of the STI regime: university, researchers, public administration, industry and stakeholders (Lepori 2011), all struggling for the definition of settings of participation and of administrative and political control (Buisson-Fenet 2008). We put in the fore historic and recent transformations of these socio-political spaces, to apprehend the complexity of institutions, norms, discourses and networks of the different stakeholders and to analyse how they adapted to the new set of policy instruments. In reference to the new avenue for public policy analysis of the "instruments in action" (Lascoumes & Le Galès 2007), we consider instrument as socio-technical device, carrying a concrete concept of the politics/society relationship, as well as meanings and representations. The choice of an instrument itself is a dynamic translation process (Callon 1986) and the use of methodological approaches derived from ANT help unveil the dynamics of institutional innovation and organisational learning: the researcher observes how actors mobilise objects and are being constrained by them, giving shape to internal procedures of categorisation and hierarchisation, with identification processes contributing to the definition of institutional boundaries (Douglas, 1986). The fieldwork thoroughly deconstructed emerging policy instruments and put them in perspective with the other policy support schemes used by the same researchers. The analysis of the transformation / emergence of instruments contributes to illuminate the diversity of networks, in terms of forms of cooperation, heterogeneity, power relations, time perspectives and representations. This instrumental polyphony can be considered as an asset, particularly for those researchers capable of strategically using them (Shinn & Lamy 2006). An instrument is dynamic, undergoing continuous transformation to adapt to contingency (Rayner 1986). Eg. the research council FNRS was settled in 1927 as a structure of collegiality and it consistently refused to become a part of a formal administration with its specific hierarchy. Recent transformations show confrontation of the logic of mutuality with a logic of global marketisation. In order to enrich the theoretical discussions, we propose to confront the propositions derived from the culturalist approach of coordination schemes (the grid/group cultural theory by Douglas (1986) and mobilised by Hood (1998) distinguishes four basic organizational types: hierarchic, fatalist, egalitarian and individualist; each of them favouring a specific mode of cooperation and control : random /mutuality /hierarchy / market) with the lessons we could learn by using the conceptual framework proposed by Lepori (2011). In their review of the "institutional dynamics of culture", 6 & Mars (2008) showed how the work of Douglas (1986) permeated most disciplines of social sciences: considering the four basic institutional forms of Douglas (1986), researchers further analysed how "anomalies" (anomalies under the system of classification that operate in a given institutional setting) are signs of on going hybridisation and social change (Thompson 1996) grounded on endogenous institutional dynamics. Made visible through a fieldwork mapping emerging hybrid forms, conflicts between the institutional forms are to be analysed as drivers of change. This is also central in the work launched by Hood on the "Art of the State" (1998) when considering the limited forms of institutional coordination to be found in public administrations and in the analysis of policy instruments. [less ▲]

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See detailImpact of global climate change and desertification on the environment and society in Southern Centre of Vietnam (a case study in Binh Thuan province). Climate today and tomorrow: state of play and perception.
Ozer, Pierre ULg

Report (2012)

The Province of Binh Thuan is the driest area of Vietnam. It is felt as being affected by desertification processes that are mainly resulting from the ongoing „climate change‟, especially shortening ... [more ▼]

The Province of Binh Thuan is the driest area of Vietnam. It is felt as being affected by desertification processes that are mainly resulting from the ongoing „climate change‟, especially shortening rainfall. But has climate, and especially precipitations, really changed in recent years? Or is the recent increase of agricultural activities with higher water needs may explain such perception of a changing climate? In the collection of four papers presented hereafter, we try to answer to these questions. Yet, the first paper investigates recent trends in precipitation and temperatures using daily data from the weather station of Phan Thiet. It appears that the area did not experience any significant precipitation decrease (rainfall have, at the contrary, globally increased) but a very significant increase in temperature. The second paper focuses on future climate projections (that is 2046-2065 and 2081-2100 compared to historical data 1970-1999). It shows that the Province of Binh Thuan will face an increase of mean temperature of about 1.6°C (over 2046-2065) and 2.5°C (over 2081-2100) and an increase of extreme temperatures and extreme rainfall events. However, no significant changes about the evolution of the annual amount of precipitation were found. It also indicates that the dry season is likely to be longer in 2046-2065 owing to a delay in the onset of the rainy season (up to 15 days) accompanied by an earlier end of the rainy season (up to 30 days). The third paper explores recent land use and land cover changes in the Province of Binh Thuan. Comparisons of the land cover maps reveal that a steady growth in population has caused extensive changes of land cover throughout the area. The maps also indicate that the loss of woody land (forest) and the extension of irrigated area, combined with built-up encroachment, remains one of the most serious environmental problems today. Yet, results showed over the 12-year span, approximately 115,120 ha of forests were converted respectively to brush, irrigated area, cropland and built-up. This is an overall average decrease of approximately 9,594 ha of forested area per year. Based on the identified causes of these changes, we made policy recommendations for better management of land use and land cover. Such results show that water needs are always increasing due to the extension of irrigated areas. The last paper concludes with a case study of a fishing village disappearing as a result of shoreline erosion. It shows that the term “climate change” is misused probably because it is easier to blame a global issue rather than the local mismanagement of natural resources, the lack of land use planning and the nonexistence of policies focused on natural hazard management in the uncontrolled construction the seaside resort of Mui Ne. This reflexion about the wrong perception of climate change which may cause several economic problems could be extended to water availability which may not be sufficient to support recent developments of irrigated agriculture. Understanding current problems may help developing adaptation strategies in the next decades. Further research is needed to understand such perception of climate change, especially when knowing that future climate may be really affected by an increase of extreme rainfall events and an extended dry season. [less ▲]

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See detailImmuno-inflammatory mechanisms in refractory asthma
Manise, Maïté ULg

Doctoral thesis (2012)

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See detailQue disent les corps lorsque Sartre rencontre Baader?
Cormann, Grégory ULg; Hamers, Jérémy ULg

Scientific conference (2012, March 15)

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See detailHybrid material for electromagnetic absorption
Detrembleur, Christophe ULg; Molenberg, Isabel; Huynen, Isabelle et al

Patent (2012)

The present invention relates to a hybrid material (10) for absorbing electromagnetic radiation (60) and a method for making such a material. The hybrid material (10) comprises at least one grid panel (20 ... [more ▼]

The present invention relates to a hybrid material (10) for absorbing electromagnetic radiation (60) and a method for making such a material. The hybrid material (10) comprises at least one grid panel (20) of thickness t 1 having holes (25) traversing said thickness t 1 , at least one polymer composite material (30) of thickness t 2 filling at least partially the holes (25) of the at least one grid panel (20), said at least one polymer composite material (30) including a polymer matrix (40) and conductive particles (50) dispersed into said polymer matrix (40), characterized in that the internal surface of the holes (25) of the at least one grid panel (20) is metallic. [less ▲]

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See detailMise au point d'un Système d'Information Géographique (SIG), à l'échelle de la parcelle, pour l'évaluation du risque de pollution des eaux de surface et souterraines par l'usage des pesticides.
Bah, Boubacar Billo ULg; Limbourg, Quentin; Vandendael, Laurent et al

in Conférence sur les Techniques d’Application de Produits de Protection des Plantes. 15 et 16 mars 2012, Lyon, France (2012, March 15)

L’étude aborde la mise au point d’un outil SIG décisionnel, basé sur une approche « expert » par logique floue, pour l’évaluation du risque de pollution des eaux de surface et souterraines par les ... [more ▼]

L’étude aborde la mise au point d’un outil SIG décisionnel, basé sur une approche « expert » par logique floue, pour l’évaluation du risque de pollution des eaux de surface et souterraines par les pesticides. Une enquête de terrain combinée aux propriétés physico-chimiques des pesticides, a permis d’identifier la pression polluante agricole liée aux propriétés des pesticides et aux activités anthropiques. La sensibilité des sols au transfert des pesticides vers les eaux de surface et souterraines a été évaluée sur base, d’une part d’une approche par modélisation mécaniste, et d’autre part à partir de l’exploitation de l’information qualitative de la carte des sols, jugée pertinente et non explicitement valorisée par le modèle mécaniste. L’évaluation du risque global a ensuite été réalisée à partir de la construction d’un système expert basée sur la logique floue, qui intègre les évaluations spécifiques aux propriétés des pesticides, aux pratiques culturales et à la sensibilité des sols au transfert des pesticides vers les eaux, en tant que milieu transit-vecteur. L’approche par « logique floue » est un outil robuste qui permet notamment d’agréger de façon uniforme des informations de sources variées, mais aussi d’intégrer l’incertitude (imprécision) associée à certaines données, telles que celles liées aux caractéristiques physico-chimiques des pesticides ou des sols. [less ▲]

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See detailLand Cover Dynamics (1990-2002) in Binh Thuan Province, Southern Central Vietnam
Hountondji, Yvon ULg; De Longueville, Florence ULg; Ozer, Pierre ULg

in International Journal of Asian Social Science (2012), 2(3), 336-349

This paper describes the use of satellite imageries and GIS data for identifying key environmental characteristics of Binh Thuan Province in south central Vietnam and for detecting the major changes ... [more ▼]

This paper describes the use of satellite imageries and GIS data for identifying key environmental characteristics of Binh Thuan Province in south central Vietnam and for detecting the major changes patterns within this region. Landsat TM (1990) and Landsat ETM+ (2002) imageries were used to classify the study area into seven land use and land cover (LULC) classes. A post-classification comparison analysis was used to quantify and illustrate the various LULC conversions that took place over the 12-year span of time. Results showed that a steady growth in population has caused extensive changes of land cover throughout the area. The maps also indicate that the loss of woody land (forest) and the extension of wetlands (irrigated area), combined with built-up encroachment, remains one of the most serious environmental problems facing the Binh Thuan Province today. The post-classification change detection analysis showed that critical habitats accounted for nearly 38.5% of the intensive study area between 1990 and 2002 while 61.5% remained stable. Results also showed over the 12-year span, approximately 1151.2 km² (115.120 ha) forest were converted respectively to brush, irrigated area (wetlands), cropland and built-up. This is an overall average decrease of 9594 hectares of forested area per year. Throughout the study area, districts most affected by forest conversion to another land cover are: Bac Bihn (2798 ha/year), Than Linh (2717 ha/year), Ham Thuan Nam (1601 ha/year) and Ham Thuan Bac (1524 ha/year). Based on the identified causes of these changes, we made policy recommendations for better management of land use and land cover. [less ▲]

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See detailHybrid material for electromagnetic absorption
Detrembleur, Christophe ULg; Huynen, Isabelle; Thomassin, Jean-Michel ULg et al

Patent (2012)

The present invention relates to a hybrid material (10) for absorbing electromagnetic radiation (60) and a method for making such a material. The hybrid material (10) comprises at least one grid panel (20 ... [more ▼]

The present invention relates to a hybrid material (10) for absorbing electromagnetic radiation (60) and a method for making such a material. The hybrid material (10) comprises at least one grid panel (20) of thickness t 1 having holes (25) traversing said thickness t 1 , at least one polymer composite material (30) of thickness t 2 filling at least partially the holes (25) of the at least one grid panel (20), said at least one polymer composite material (30) including a polymer matrix (40) and conductive particles (50) dispersed into said polymer matrix (40), characterized in that the internal surface of the holes (25) of the at least one grid panel (20) is metallic. [less ▲]

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See detailLe dopage
Kaux, Jean-François ULg

Conference (2012, March 15)

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See detailEtude pluridisciplinaire de l'implication bactérienne du phénomène de blanchissement des coraux Scléractiniaires (Indo-Pacifique)
Ladrière, Ophélie ULg

Doctoral thesis (2012)

Given the increasing number of coral diseases linked to the growing impact of global warming and human activities, the present research focused on the phenomenon of coral bleaching. The Scleractinian ... [more ▼]

Given the increasing number of coral diseases linked to the growing impact of global warming and human activities, the present research focused on the phenomenon of coral bleaching. The Scleractinian Cnidaria are the essential building blocks of the coral reef ecosystem, whose ecological, economic and societal interests are demonstrated. The symptom of bleaching has multiple and complex causes that are still unclear. It corresponds to the rupture of the mutualistic symbiosis between the coral and microalgae, called zooxanthellae, and can causes death of many corals. An assumption underlying this phenomenon suggests that corals are bleaching by the action of pathogenic bacteria, penetrating inside the coral tissues. However, this hypothesis seems quite controversial and the present work attempts to elucidate a set of issues surrounding this controversy. To do this, a multidisciplinary approach combining ecology (general and microbial) and molecular biology has been established through field and experimental studies. Using electron microscopy, morphological criteria were established to characterize the status of coral bleaching. Furthermore, this technique was also used to identify different types of bacteria within coral tissues. Their presence and their role within the coral holobiont were discussed. Several molecular biology techniques (DGGE, sequencing) have provided evidences on the non-specificity of bacterial communities associated with corals species, sampling sites and different status of bleaching. This non-specificity shows that the functions performed by bacteria in the coral holobiont could be the result of opportunistic bacteria from various taxonomic groups. The presence of Cyanobacteria in some corals, detected by microscopy and confirmed by molecular techniques, raises the question about their role within the holobiont and the alternative pathway that they offer for the symbiotic host compared with zooxanthellae. The issues of potential competition between these different symbionts or the benefit of this symbiotic diversity, in case of bleaching event, remain open. Transcriptomic genetics was used to study the response of coral facing a bacterial stress in different experimental conditions of temperature determining the expression of bacterial virulence. Studying the expression profile of genes involved in immunity of the coral allowed to understand the sequence of reactions and changes in resource allocation in response to different stages of bacterial infection. On this experiment, the first antimicrobial peptide of Scleractinia, the damicornin, has been identified and characterized. All these results suggest that the context of changes in environmental parameters is more important than the presence of pathogens itself. The bacteria would then act as an aggravating factor in a situation where the coral, already weakened and stressed, cannot defend itself adequately. Finally, the observation of an increase in cnidocytes in a coral species that has undergone bleaching, suggests that some coral species are able to shift to a more heterotrophic nutritional regime adapting to the lack of inputs caused by the significant loss of zooxanthellae. This would favor the resilience of coral. [less ▲]

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