References of "2012"
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See detailA fully nonlinear finite element model for orthodontic tooth movement prediction
Mengoni, Marlène ULg; D'Otreppe, Vinciane ULg; Ponthot, Jean-Philippe ULg

in Proceedings of the 10th International Symposium on Computer Methods in Biomechanics and Biomedical Engineering. (2012, April)

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See detailTip cells at the top: multiscale modeling of angiogenesis during fracture healing
Carlier, Aurélie ULg; Geris, Liesbet ULg; Van Oosterwyck, Hans

in Computer Methods in Biomechanics and Biomedical Engineering (CMBBE) - Proceedings (2012, April)

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See detailROLE OF ACTIVE ERP PARADIGMS IN AWARENESS DETECTION IN NON RESPONSIVE PATIENTS
Lugo, Zulay; Lesenfants, Damien ULg; Lehembre, Remy ULg et al

in Proceedings of the 1st international DECODER Workshop (2012, April)

The role of active vs. passive ERP paradigms in disorders of consciousness is assessed in this case study of a LIS patient. Results show that despite absent P3 in a passive auditory task, the patient ... [more ▼]

The role of active vs. passive ERP paradigms in disorders of consciousness is assessed in this case study of a LIS patient. Results show that despite absent P3 in a passive auditory task, the patient displayed significant differences in the active task. This study shows the importance of using a large battery of tests when assessing DOC patients. [less ▲]

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See detailEuropese rechtspraak : actualia/ actualités: jurisprudence de la Cour de Justice
Durviaux, Ann-Lawrence ULg

in Marchés et Contrats Publics = Overheidsopdrachten en -Overeenkomsten (2012), 1/2012

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See detailL'immersion linguistique en contexte de mobilité Erasmus
Meunier, Deborah ULg

Scientific conference (2012, April)

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See detailImaginaires de la vie littéraire. Fiction, figuration, configuration
Dozo, Björn-Olav ULg; Glinoer, Anthony; Lacroix, Michel

Book published by Presses universitaires de Rennes (2012)

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See detailPosture polémique ou polémisation de la posture ?
Moor, Louise ULg

in COnTEXTES : Revue de Sociologie de la Littérature (2012), 10

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See detailMacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.
Creppe, Catherine ULg; Janich, Peggy; Cantarino, Neus et al

in Molecular and cellular biology (2012), 32(8), 1442-52

One of the most striking epigenetic alterations that occurs at the level of the nucleosome is the complete exchange of the canonical H2A histones for the macroH2A variant. Here, we provide insight into ... [more ▼]

One of the most striking epigenetic alterations that occurs at the level of the nucleosome is the complete exchange of the canonical H2A histones for the macroH2A variant. Here, we provide insight into the poorly recognized function of macroH2A in transcriptional activation and demonstrate its relevance in embryonic and adult stem cells. Knockdown of macroH2A1 in mouse embryonic stem (mES) cells limited their capacity to differentiate but not their self-renewal. The loss of macroH2A1 interfered with the proper activation of differentiation genes, most of which are direct target genes of macroH2A. Additionally, macroH2A1-deficient mES cells displayed incomplete inactivation of pluripotency genes and formed defective embryoid bodies. In vivo, macroH2A1-deficient teratomas contained a massive expansion of malignant, undifferentiated carcinoma tissue. In the heterogeneous culture of primary human keratinocytes, macroH2A1 levels negatively correlated with the self-renewal capacity of the pluripotent compartment. Together these results establish macroH2A1 as a critical chromatin component that regulates the delicate balance between self-renewal and differentiation of embryonic and adult stem cells. [less ▲]

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See detailDynamic interaction between lymphoid tyrosine phosphatase and C-terminal Src kinase controls T cell activation
Tautz, Lutz; Vang, Torkel; Liu, Wallace et al

in FASEB Journal (2012, April), 26

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner ... [more ▼]

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we show that dissociation of the LYP/CSK complex is necessary for recruitment of LYP to lipid rafts, where it down-modulates TCR-mediated signaling. Our findings may also explain the reduced TCR signaling associated with a single nucleotide polymorphism, which confers increased risk for autoimmunity and results in the expression of a LYP allele that can no longer bind CSK. Development of a potent and selective chemical probe of LYP allowed us to confirm that the observed down-modulation of TCR-induced signaling was due to the LYP catalytic activity. Our compound also represents a starting point for the development of a LYP-based treatment of autoimmunity. [less ▲]

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See detailRevealing MPLS Tunnels Obscured from Traceroute
Donnet, Benoît ULg; Luckie, Matthew; Mérindol, Pascal et al

in Computer Communication Review (2012), 42(2), 87-93

Operators have deployed Multiprotocol Label Switching (MPLS) in the Internet for over a decade. However, its impact on Internet topology measurements is not well known, and it is possible for some MPLS ... [more ▼]

Operators have deployed Multiprotocol Label Switching (MPLS) in the Internet for over a decade. However, its impact on Internet topology measurements is not well known, and it is possible for some MPLS configurations to lead to false router-level links in maps derived from traceroute data. In this paper, we introduce a measurement-based classification of MPLS tunnels, identifying tunnels where IP hops are revealed but not explicitly tagged as label switching routers, as well as tunnels that obscure the underlying path. Using a large-scale dataset we collected, we show that paths frequently cross MPLS tunnels in today's Internet: in our data, at least 30% of the paths we tested traverse an MPLS tunnel. We also propose and evaluate several methods to reveal MPLS tunnels that are not explicitly flagged as such: we discover that their fraction is significant (up to half the explicit tunnel quantity) but most of them do not obscure IP-level topology discovery. [less ▲]

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See detailMultidisciplinary and Evidence-based Method for Prioritizing Diseases of Food-producing Animals and Zoonoses
Humblet, Marie-France ULg; Vandeputte, Sébastien ULg; Albert, Adelin ULg et al

in Emerging Infectious Diseases (2012), 18(4),

To prioritize 100 animal diseases and zoonoses in Europe, we used a multicriteria decision-making procedure based on opinions of experts and evidence-based data. Forty international experts performed ... [more ▼]

To prioritize 100 animal diseases and zoonoses in Europe, we used a multicriteria decision-making procedure based on opinions of experts and evidence-based data. Forty international experts performed intracategory and intercategory weighting of 57 prioritization criteria. Two methods (deterministic with mean of each weight and probabilistic with distribution functions of weights by using Monte Carlo simulation) were used to calculate a score for each disease. Consecutive ranking was established. Few differences were observed between each method. Compared with previous prioritization methods, our procedure is evidence based, includes a range of fields and criteria while considering uncertainty, and will be useful for analyzing diseases that affect public health [less ▲]

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See detailExperimental Results of Flat Fresnel Doublets made of PMMA and PC
Languy, Fabian ULg; Fleury-Frenette, Karl ULg; Lenaerts, Cedric ULg et al

Conference (2012, April)

To reduce the chromatic aberration lots of imaging systems like cameras and telescopes turn to achromatic doublets. On the other hand, to be cheaper, lighter and thinner, more and more systems like ... [more ▼]

To reduce the chromatic aberration lots of imaging systems like cameras and telescopes turn to achromatic doublets. On the other hand, to be cheaper, lighter and thinner, more and more systems like projectors and headlights use Fresnel lenses. To combine high performances and low cost, the use achromatic Fresnel doublets has been investigated. [less ▲]

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See detailCumulative pregnancy rate after ICSI-IVF in patients with colorectal endometriosis: results of a multicentre study.
Ballester, Marcos; d'Argent, EM; Morcel, K et al

in Human Reproduction (2012), 27(4), 1043-9

BACKGROUND: There is currently no consensus about indications for surgery for infertility associated with colorectal endometriosis. The aim of this study was to evaluate cumulative pregnancy rates (CPRs ... [more ▼]

BACKGROUND: There is currently no consensus about indications for surgery for infertility associated with colorectal endometriosis. The aim of this study was to evaluate cumulative pregnancy rates (CPRs) after ICSI-IVF cycles in patients with colorectal endometriosis and to identify determinant factors of fertility outcome. METHODS: Prospective longitudinal multicentre study from January 2005 to June 2011. We included 75 patients with colorectal endometriosis and proved infertility without prior surgery for deep infiltrating endometriosis. Univariable analysis was used to identify determinant factors of pregnancy rate. CPR was calculated using cumulative-incidence methods from log-rank test and Kaplan-Meier curves. For multivariable analysis, Cox proportional hazards model was used. RESULTS: For CPR per patient analysis, the total number of cycles was 113 and the median number of cycles per patient was 1 (range: 1-3). In the whole population the CPR per patient after three ICSI-IVF cycles was 68.6%. The CPR for patients with or without associated adenomyosis was 19 and 82.4%, respectively (P= 0.01). In addition, a patient age over 35 years (P= 0.02) and anti-Mullerian hormone serum level under 2 ng/ml (P= 0.02) were associated with a decreased CPR per patient. At multivariable analysis, adenomyosis [HR = 0.34, 95% CI (0.12-0.99), P= 0.49] was associated with a decreased CPR. CONCLUSIONS: Our data confirm that ICSI-IVF offers a high CPR per patient. However, determinant factors of CPR should be taken into account when informing couples of their options. [less ▲]

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See detailDu théâtre magique au cinéma fantastique : les figures extatiques de Georges Méliès
Tomasovic, Dick ULg

in Gimello-Mesplomb, Frédéric (Ed.) Le Cinéma fantastique français à l’épreuve du genre fantastique. Socioanalyse d’une production artistique (2012)

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See detailLe statut du “logos” dans Être et temps.
Gauvry, Charlotte ULg

Conference (2012, April)

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See detailToward a Taxonomy of Key Success Factors for SME’s in a Changing Environment : the case of the Luxury Industry
Riguelle, France ULg; Van Caillie, Didier ULg

in Proceedings of the The 12th IAMB Conference (2012, April)

This paper aims at proposing a synthetic taxonomy of key success factors (KSF) for SME's in the luxury industry. Both typologies of KSF for SME's in overall on the one hand, and for companies of the ... [more ▼]

This paper aims at proposing a synthetic taxonomy of key success factors (KSF) for SME's in the luxury industry. Both typologies of KSF for SME's in overall on the one hand, and for companies of the luxury industry on the other hand, constructed on a basis of a critical literature review regarding the two domains concerned (SME's performance management and performance management of companies of the luxury industry) are gathered to propose a single synthetic taxonomy of KSF for SME's of the luxury industry. [less ▲]

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See detailObserved and simulated time evolution of HCl, ClONO2, and HF total column abundances
Kohlhepp, R; Ruhnke, R; Chipperfield, M P et al

in Atmospheric Chemistry and Physics (2012), 12(7), 3527--3556

Time series of total column abundances of hydrogen chloride (HCl), chlorine nitrate (ClONO2), and hydrogen fluoride (HF) were determined from ground-based Fourier transform infrared (FTIR) spectra ... [more ▼]

Time series of total column abundances of hydrogen chloride (HCl), chlorine nitrate (ClONO2), and hydrogen fluoride (HF) were determined from ground-based Fourier transform infrared (FTIR) spectra recorded at 17 sites belonging to the Network for the Detection of Atmospheric Composition Change (NDACC) and located between 80.05°N and 77.82°S. By providing such a near-global overview on ground-based measurements of the two major stratospheric chlorine reservoir species, HCl and ClONO2, the present study is able to confirm the decrease of the atmospheric inorganic chlorine abundance during the last few years. This decrease is expected following the 1987 Montreal Protocol and its amendments and adjustments, where restrictions and a subsequent phase-out of the prominent anthropogenic chlorine source gases (solvents, chlorofluorocarbons) were agreed upon to enable a stabilisation and recovery of the stratospheric ozone layer. The atmospheric fluorine content is expected to be influenced by the Montreal Protocol, too, because most of the banned anthropogenic gases also represent important fluorine sources. But many of the substitutes to the banned gases also contain fluorine so that the HF total column abundance is expected to have continued to increase during the last few years. The measurements are compared with calculations from five different models: the two-dimensional Bremen model, the two chemistry-transport models KASIMA and SLIMCAT, and the two chemistry-climate models EMAC and SOCOL. Thereby, the ability of the models to reproduce the absolute total column amounts, the seasonal cycles, and the temporal evolution found in the FTIR measurements is investigated and inter-compared. This is especially interesting because the models have different architectures. The overall agreement between the measurements and models for the total column abundances and the seasonal cycles is good. Linear trends of HCl, ClONO2, and HF are calculated from both measurement and model time series data, with a focus on the time range 2000–2009. This period is chosen because from most of the measurement sites taking part in this study, data are available during these years. The precision of the trends is estimated with the bootstrap resampling method. The sensitivity of the trend results with respect to the fitting function, the time of year chosen and time series length is investigated, as well as a bias due to the irregular sampling of the measurements. The measurements and model results investigated here agree qualitatively on a decrease of the chlorine species by around 1%yr-1. The models simulate an increase of HF of around 1%yr-1. This also agrees well with most of the measurements, but some of the FTIR series in the Northern Hemisphere show a stabilisation or even a decrease in the last few years. In general, for all three gases, the measured trends vary more strongly with latitude and hemisphere than the modelled trends. Relative to the FTIR measurements, the models tend to underestimate the decreasing chlorine trends and to overestimate the fluorine increase in the Northern Hemisphere. At most sites, the models simulate a stronger decrease of ClONO2 than of HCl. In the FTIR measurements, this difference between the trends of HCl and ClONO2 depends strongly on latitude, especially in the Northern Hemisphere. [less ▲]

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