References of "2012"
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See detailEnsembles reconnaissables de rationnels
Charlier, Emilie ULg

Scientific conference (2012, April)

In this talk I will introduce the recognizable sets of rationals, following the formalism of Jeffrey Shallit. I will point out several open questions regarding this topic.

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See detailDevelopment of a biomechanical model of deer antler cancellous bone based on X-ray microtomographic images
de Bien, Charlotte ULg; Mengoni, Marlène ULg; D'Otreppe, Vinciane ULg et al

in Micro-CT User Meeting 2012 - Abstract Book (2012, April)

Finite element models accurately compute the mechanical response of bone and bone-like materials when the models include their detailed microstructure. The aim of this paper is to develop and validate a ... [more ▼]

Finite element models accurately compute the mechanical response of bone and bone-like materials when the models include their detailed microstructure. The aim of this paper is to develop and validate a biomechanical model for deer antler cancellous bone tissue based on X-ray microtomographic images. In order to simulate the mechanical behavior under compressive load using a finite element model, images obtained by X-ray microtomography were exported into Metafor, which is an non-linear finite element software initially developed at University of Liège for metal forming processes. This software has recently found biomedical applications. The ultimate goal is to compare model predictions with the mechanical behavior observed experimentally using the Skyscan material testing stage under compression mode. The creation of the biomechanical model mesh from segmented μCT images, its integration into the software Metafor and the simulation of a compression test are described in this paper. [less ▲]

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See detailImaginaires de la vie littéraire. Fiction, figuration, configuration
Dozo, Björn-Olav ULg; Glinoer, Anthony; Lacroix, Michel

Book published by Presses universitaires de Rennes (2012)

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See detailDegradation inhibitors and metal additives: impact on solvent degradation
Léonard, Grégoire ULg

Report (2012)

This report is part of a PhD thesis currently taking place at the University of Liège in collaboration with the company Laborelec. A Degradation Test Rig (DTR) has been built in order to evaluate solvent ... [more ▼]

This report is part of a PhD thesis currently taking place at the University of Liège in collaboration with the company Laborelec. A Degradation Test Rig (DTR) has been built in order to evaluate solvent degradation in CO2 capture conditions. Details about degradation effects and about the DTR may be found in a previous report (PhD mid-term report, G. Léonard, 2011). Experiments to study the effect of process conditions on degradation are in progress with 2-ethanolamine (MEA) as benchmark solvent. This report presents first a brief overview of the different degradation mechanisms and associated products, followed by a literature review about metal influence on MEA degradation and a state of the art review about degradation inhibitors. [less ▲]

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See detailEngineering geological mapping in Wallonia (Belgium) : present state and recent computerized approach
Delvoie, Simon ULg; Radu, Jean-Pol ULg; Ruthy, Ingrid ULg et al

Poster (2012, April)

An engineering geological map can be defined as a geological map with a generalized representation of all the components of a geological environment which are strongly required for spatial planning ... [more ▼]

An engineering geological map can be defined as a geological map with a generalized representation of all the components of a geological environment which are strongly required for spatial planning, design, construction and maintenance of civil engineering buildings. In Wallonia (Belgium) 24 engineering geological maps have been developed between the 70s and the 90s at 1/5,000 or 1/10,000 scale covering some areas of the most industrialized and urbanized cities (Liège, Charleroi and Mons). They were based on soil and subsoil data point (boring, drilling, penetration test, geophysical test, outcrop. . . ). Some displayed data present the depth (with isoheights) or the thickness (with isopachs) of the different subsoil layers up to about 50 m depth. Information about geomechanical properties of each subsoil layer,useful for engineers and urban planners, is also synthesized. However, these maps were built up only on paper and progressively needed to be updated with new soil and subsoil data. The Public Service of Wallonia and the University of Liège have recently initiated a study to evaluate the feasibility to develop engineering geological mapping with a computerized approach. Numerous and various data (about soil and subsoil) are stored into a georelational database (the geotechnical database – using Access, Microsoft®). All the data are geographically referenced. The database is linked to a GIS project (using ArcGIS, ESRI®). Both the database and GIS project consist of a powerful tool for spatial data management and analysis. This approach involves a methodology using interpolation methods to update the previous maps and to extent the coverage to new areas. The location (x, y, z) of each subsoil layer is then computed from data point. The geomechanical data of these layers are synthesized in an explanatory booklet joined to maps. [less ▲]

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See detailLa médiation scolaire. Un regard des acteurs sur leurs pratiques
Kuty, Olgierd ULg; Schoenaers, Frédéric ULg; Dubois, Christophe ULg et al

Book published by Presses Universitaires de Liège (2012)

Dans nos sociétés en réseaux qui se caractérisent par un pluralisme normatif, on peut faire société sans partager des valeurs communes. Le fonctionnement des institutions scolaires illustre les nouveaux ... [more ▼]

Dans nos sociétés en réseaux qui se caractérisent par un pluralisme normatif, on peut faire société sans partager des valeurs communes. Le fonctionnement des institutions scolaires illustre les nouveaux modes de régulation des tensions, de la diversité, de l'intégration, etc. désormais à l’œuvre. C'est dans ce contexte que le concept de médiation a fait son apparition dans nos écoles, comme dispositif d'apaisement ou de maintien du lien social. La diffusion de tels dispositifs doit beaucoup à la création de services centraux puis locaux de médiation, tout comme au travail de nombreux médiateurs qui ont progressivement investi le champ scolaire. Cet ouvrage constitue une exploration du développement de leur fonction et il rend compte de la culture professionnelle qui les anime. Cette exploration conduit à s'interroger sur le processus de diffusion de la médiation scolaire tout en contextualisant cette dernière dans le spectre plus large de la médiation en général, un concept désormais répandu dans les champs familiaux, judiciaires, sanitaires, administratifs, politiques et sociaux les plus divers. [less ▲]

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See detailTyrosine-dependent capture of CAP-Gly domain‐containing proteins in complex mixture by EB1 C-terminal peptidic probes
Calligaris, David ULg; Manatschal, Cristina; Marcellin, Marlène et al

in Journal of Proteomics (2012), 75

Microtubule dynamics is regulated by an array of microtubule associated proteins of which the microtubule plus-end tracking proteins (+TIPs) are prominent examples. +TIPs form dynamic interaction networks ... [more ▼]

Microtubule dynamics is regulated by an array of microtubule associated proteins of which the microtubule plus-end tracking proteins (+TIPs) are prominent examples. +TIPs form dynamic interaction networks at growing microtubule ends in an EB1-dependent manner. The interaction between the C-terminal domain of EB1 and the CAP-Gly domains of the +TIP CLIP-170 depends on the last tyrosine residue of EB1. In the present study, we generated peptidic probes corresponding to the C-terminal tail of EB1 to affinity-capture binding partners from cell lysates. Using an MS-based approach, we showed that the last 15 amino-acid residues of EB1, either free or immobilized on beads, bound recombinant CAP-Gly domains of CLIP-170. We further demonstrate that this binding was prevented when the C-terminal tyrosine of EB1 was absent in the peptidic probes. Western blotting in combination with a label-free quantitative proteomic analysis revealed that the peptidic probe harboring the C-terminal tyrosine of EB1 effectively pulled-down proteins with CAP-Gly domains from endothelial cell extracts. Additional proteins known to interact directly or indirectly with EB1 and the microtubule cytoskeletonwere also identified. Our peptidic probes represent valuable tools to detect changes induced in EB1-dependent +TIP networks by external cues such as growth factors and small molecules. [less ▲]

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See detailFood control & food crisis: challenges in analyses
Focant, Jean-François ULg

Scientific conference (2012, April)

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See detailUN MILIEU CINÉMATIQUE POUR L'ÉLABORATION D'UNE PRAXÉOLOGIE « MODÉLISATION » DU THÉORÈME FONDAMENTAL DU CALCUL DIFFÉRENTIEL ET INTÉGRAL
Balhan, Kevin ULg

in ENSEIGNEMENT DES MATHÉMATIQUES ET CONTRAT SOCIAL ENJEUX ET DÉFIS POUR LE 21e SIÈCLE (2012, April)

The text is related to the calculus’s main theorem learning as it is studied by students in the last year of Belgium secondary school. We make an epistemological analysis of the theorem that inspired us ... [more ▼]

The text is related to the calculus’s main theorem learning as it is studied by students in the last year of Belgium secondary school. We make an epistemological analysis of the theorem that inspired us the set up of a situation composed of four mathematics statements and for which we need rectilinear movements with or without variable speeds, speeding and moving laws, areas, volumes and flows. The suggested strategies for these statements and the reactions will be analysed later. [less ▲]

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See detailLes dates des élections depuis 1830
Bouhon, Frédéric ULg

in Bouhon, Frédéric; Reuchamps, Min (Eds.) Les systèmes électoraux de la Belgique (2012)

Cette contribution constitue une annexe d'un ouvrage collectif sur les systèmes électoraux de la Belgique. Elle vise à présenter, sous la forme de tableaux, les dates des élections en Belgique à tous les ... [more ▼]

Cette contribution constitue une annexe d'un ouvrage collectif sur les systèmes électoraux de la Belgique. Elle vise à présenter, sous la forme de tableaux, les dates des élections en Belgique à tous les niveaux de pouvoir depuis 1830. [less ▲]

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See detailMacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.
Creppe, Catherine ULg; Janich, Peggy; Cantarino, Neus et al

in Molecular and cellular biology (2012), 32(8), 1442-52

One of the most striking epigenetic alterations that occurs at the level of the nucleosome is the complete exchange of the canonical H2A histones for the macroH2A variant. Here, we provide insight into ... [more ▼]

One of the most striking epigenetic alterations that occurs at the level of the nucleosome is the complete exchange of the canonical H2A histones for the macroH2A variant. Here, we provide insight into the poorly recognized function of macroH2A in transcriptional activation and demonstrate its relevance in embryonic and adult stem cells. Knockdown of macroH2A1 in mouse embryonic stem (mES) cells limited their capacity to differentiate but not their self-renewal. The loss of macroH2A1 interfered with the proper activation of differentiation genes, most of which are direct target genes of macroH2A. Additionally, macroH2A1-deficient mES cells displayed incomplete inactivation of pluripotency genes and formed defective embryoid bodies. In vivo, macroH2A1-deficient teratomas contained a massive expansion of malignant, undifferentiated carcinoma tissue. In the heterogeneous culture of primary human keratinocytes, macroH2A1 levels negatively correlated with the self-renewal capacity of the pluripotent compartment. Together these results establish macroH2A1 as a critical chromatin component that regulates the delicate balance between self-renewal and differentiation of embryonic and adult stem cells. [less ▲]

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See detailThe earthquake sedimentary record in marine sediment from cores in the western part of the Marmara Sea, Turkey
Drab, Laureen; Hubert, Aurelia ULg; Schmidt, Sabine et al

Conference (2012, April)

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See detailAn oblique view on the role of spindle orientation in vertebrate neurogenesis
Peyre, Elise ULg; Morin, Xavier

in Development, Growth & Differentiation (2012)

Neurogenesis is a dynamic process that produces a diverse number of glial and neural cell types from a limited number of neural stem cells throughout development and into adulthood. After an initial ... [more ▼]

Neurogenesis is a dynamic process that produces a diverse number of glial and neural cell types from a limited number of neural stem cells throughout development and into adulthood. After an initial period of amplification through symmetric division, neural stem cells rely on asymmetric modes of division to self-renew while producing more committed progeny. Understanding the molecular mechanisms regulating the choice between symmetric and asymmetric modes of division is essential to understand human brain development and pathologies, and to explain the increasing cortical complexity observed in evolution. A popular model states the existence of a causal relationship between the orientation of the axis of division of stem cells and the fate of their progeny in many different tissues, but the validity of the model in neural stem cells is not clear. In this review, we briefly present the diversity of neural stem cells and intermediate progenitors in the developing central nervous system. We then draw a historic overview of the assumed causal relationship between spindle orientation and fate determination. We show how this prompted a search for regulators of spindle orientation, and present the current state of knowledge on the mechanism. Finally, we review data on the effect of defective spindle orientation and try to integrate conflicting observations by presenting alternative mechanisms that may regulate the choice between symmetric and asymmetric outcomes. [less ▲]

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See detailA new species of Caprella (Crustacea: Amphipoda) from the Mediterranean Sea
Sturaro, Nicolas ULg; Guerra-García, José Manuel

in Helgoland Marine Research (2012)

A new caprellid amphipod, Caprella tavolarensis n. sp., is described based on specimens collected from a Posidonia oceanica seagrass meadow at the Tavolara- Punta Coda Cavallo Marine Protected Area ... [more ▼]

A new caprellid amphipod, Caprella tavolarensis n. sp., is described based on specimens collected from a Posidonia oceanica seagrass meadow at the Tavolara- Punta Coda Cavallo Marine Protected Area (Sardinia, Mediterranean Sea). The species is close to Caprella liparotensis, but can be clearly distinguished by smaller size, presence of a short rostrum, body elongate and dorsally smooth, absence of serrate carina on the basis of gnathopod 2 and pereopods, mouthparts scarcely setose, absence of Wne setae on peduncle of antenna 1 and absence of swimming setae on antenna 2. The number of caprellid species reported from the Mediterranean Sea has increased from 23 (1993) to 41 (2010), consequently, further taxonomical studies should be addressed to properly estimate the total amphipod diversity in the Mediterranean Sea. [less ▲]

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See detailL'astronomie dans le monde
Manfroid, Jean ULg

Article for general public (2012)

Collision dans le Dragon; Trou noir de masse intermédiaire;Zoom sur une galaxie lointaine; Les jours de Vénus s’allongent ?; Lumière cendrée; Anomalies magnétiques lunaires; Océan martien; Hercule par le ... [more ▼]

Collision dans le Dragon; Trou noir de masse intermédiaire;Zoom sur une galaxie lointaine; Les jours de Vénus s’allongent ?; Lumière cendrée; Anomalies magnétiques lunaires; Océan martien; Hercule par le VST [less ▲]

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See detailL'impact de la divulgation d'informations sur la liquidité du marché français
Ajina, Aymen ULg; Sougné, Danielle ULg; Lakhal, Faten

in Finance et Stratégies de Développement (2012)

This paper examines the relationship between the quality of financial disclosure and the French stock-market liquidity. Based on a sample of 196 firms over a period from 2004 to 2007, we find that there ... [more ▼]

This paper examines the relationship between the quality of financial disclosure and the French stock-market liquidity. Based on a sample of 196 firms over a period from 2004 to 2007, we find that there is a positive and statistically significant relationship between the quality of Annual Reports and market liquidity. This result should encourage French authorities to develop the informational environment as an indispensable means to prevent the risk of illiquidity. [less ▲]

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See detailHave STS Fallen Into a Political Void? Depoliticisation and Engagement in the Case of Nanotechnologies
Thoreau, François ULg; Delvenne, Pierre ULg

in Política & Sociedade (2012), 11(20), 205-226

In this paper we trace some of the key points in the history of Science and Technology Studies (STS). In particular we outline the inherently political dynamics of the field. Against We underline two ... [more ▼]

In this paper we trace some of the key points in the history of Science and Technology Studies (STS). In particular we outline the inherently political dynamics of the field. Against We underline two emerging patterns in the curse of STS: the one of “depoliticisation” and the one of increasing “engagement”. We address the case study nanotechnologies and discuss their intertwined history with the STS. This allows us to point at the risk that the increasing institutionalisation of STS and the political mandate that frames and stabilizes the field’s relationship to the technological developments would create a political void. We conclude that STS research is at a crossroads. It is facing an important empirical turn, which may deprive it from its political significance, and constantly redefine its institutional constraints. STS has to continuously question its underlying political assumptions (as it occurs more and more regarding public participation) and to make it explicit. [less ▲]

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See detailDynamic interaction between lymphoid tyrosine phosphatase and C-terminal Src kinase controls T cell activation
Tautz, Lutz; Vang, Torkel; Liu, Wallace et al

in FASEB Journal (2012, April), 26

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner ... [more ▼]

Lymphoid tyrosine phosphatase (LYP) and C-terminal Src kinase (CSK) are negative regulators of signaling mediated through the T cell antigen receptor (TCR) and are thought to act in a cooperative manner when forming a complex. Here, we show that dissociation of the LYP/CSK complex is necessary for recruitment of LYP to lipid rafts, where it down-modulates TCR-mediated signaling. Our findings may also explain the reduced TCR signaling associated with a single nucleotide polymorphism, which confers increased risk for autoimmunity and results in the expression of a LYP allele that can no longer bind CSK. Development of a potent and selective chemical probe of LYP allowed us to confirm that the observed down-modulation of TCR-induced signaling was due to the LYP catalytic activity. Our compound also represents a starting point for the development of a LYP-based treatment of autoimmunity. [less ▲]

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