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See detailPrevalence, genetic diversity and antiretroviral drugs resistance-asszociated mutations among untreated HIV-1-infected pregnant women in Gabon, Central Africa
CARON, Mélanie; LEKANA-DOUKI, Sonia Etenna; MAKUWA, Maria et al

in BMC Infectious Diseases (2012), 12:64

BACKGROUND: In Africa, the wide genetic diversity of HIV has resulted in emergence of new strains, rapid spread of this virus in sub-Saharan populations and therefore spread of the HIV epidemic throughout ... [more ▼]

BACKGROUND: In Africa, the wide genetic diversity of HIV has resulted in emergence of new strains, rapid spread of this virus in sub-Saharan populations and therefore spread of the HIV epidemic throughout the continent. METHODS: To determine the prevalence of antibodies to HIV among a high-risk population in Gabon, 1098 and 2916 samples were collected from pregnant women in 2005 and 2008, respectively. HIV genotypes were evaluated in 107 HIV-1-positive samples to determine the circulating subtypes of strains and their resistance to antiretroviral drugs (ARVs). RESULTS: The seroprevalences were 6.3% in 2005 and 6.0% in 2008. The main subtype was recombinant CRF02_AG (46.7%), followed by the subtypes A (19.6%), G (10.3%), F (4.7%), H (1.9%) and D (0.9%) and the complex recombinants CRF06_cpx (1.9%) and CRF11_cpx (1.9%); 12.1% of subtypes could not be characterized. Analysis of ARVs resistance to the protease and reverse transcriptase coding regions showed mutations associated with extensive subtype polymorphism. In the present study, the HIV strains showed reduced susceptibility to ARVs (2.8%), particularly to protease inhibitors (1.9%) and nucleoside reverse transcriptase inhibitors (0.9%). CONCLUSIONS: The evolving genetic diversity of HIV calls for continuous monitoring of its molecular epidemiology in Gabon and in other central African countries. [less ▲]

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See detailAvant-propos
Bousmar, Éric; Dumont, Jonathan ULg; Marchandisse, Alain ULg et al

in Bousmar, Éric; Dumont, Jonathan; Marchandisse, Alain (Eds.) et al Femmes de pouvoir, femmes politiques durant les derniers cièles du Moyen Âge et au cours de la première Renaissance (2012)

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See detailLes éleveurs d'alpaca du Pérou
Hanzen, Christian ULg; Bay, Daniel ULg

Learning material (2012)

Ce film de 52 minutes réalisé par Daniel Bay sur un scénario de Christian Hanzen présente les divers aspects du projet d'amélioration de la fibre d'alpaca financé par la Coopération Universitaire au ... [more ▼]

Ce film de 52 minutes réalisé par Daniel Bay sur un scénario de Christian Hanzen présente les divers aspects du projet d'amélioration de la fibre d'alpaca financé par la Coopération Universitaire au développement dans le cadre d'une coopération institutionnelle entre les universités de Namur (FUNDPN) et de Louvain (UCL) et l'Université Sans Antonio Abad del Cusco. Cette amélioration implique la caractérisation phénotypique de la fibre d'alpaca mais également l'amélioration des biotechnologies de la reproduction du mâle et de la femelle alpaca. [less ▲]

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See detailBiogeography of the two major arbovirus mosquito vectors, Aedes aegypti and Aedes albopictus (Diptera, Culicidae), in Madagascar.
Raharimalala, Fara Nantenaina ULg; Raveloson Ravaomanarivo, Lala Harivelo; Ravelonandro, Pierre et al

in Parasites & Vectors (2012), 5(55), 1-10

Background: In the past ten years, the Indian Ocean region has been the theatre of severe epidemics of chikungunya and dengue. These outbreaks coincided with a high increase in populations of Aedes ... [more ▼]

Background: In the past ten years, the Indian Ocean region has been the theatre of severe epidemics of chikungunya and dengue. These outbreaks coincided with a high increase in populations of Aedes albopictus that outcompete its sister taxon Aedes aegypti in most islands sampled. The objective of this work was to update the entomological survey of the two Aedes species in the island of Madagascar which has to face these arboviroses. Methods: The sampling of Aedes mosquitoes was conducted during two years, from October 2007 to October 2009, in fifteen localities from eight regions of contrasting climates. Captured adults were identified immediately whereas immature stages were bred until adult stage for determination. Phylogenetic analysis was performed using two mtDNA genes, COI and ND5 and trees were constructed by the maximum likelihood (ML) method with the gene time reversible (GTR) model. Experimental infections with the chikungunya virus strain 06.21 at a titer of 107.5 pfu/mL were performed to evaluate the vector competence of field-collected mosquitoes. Disseminated infection rates were measured fourteen days after infection by immunofluorescence assay performed on head squashes. Results: The species Aedes aegypti was detected in only six sites in native forests and natural reserves. In contrast, the species Aedes albopictus was found in 13 out of the 15 sites sampled. Breeding sites were mostly found inman-made environments such as discarded containers, used tires, abandoned buckets, coconuts, and bamboo cuts. Linear regression models showed that the abundance of Ae. albopictus was significantly influenced by the sampling region (F = 62.00, p < 2.2 × 10-16) and period (F = 36.22, p = 2.548 × 10-13), that are associated with ecological and climate variations. Phylogenetic analysis of the invasive Ae. albopictus distinguished haplotypes from South Asia and South America from those of Madagascar, but the markers used were not discriminant enough to discern Malagasy populations. The experimental oral infection method showed that six Ae. albopictus populations exhibited high dissemination infection rates for chikungunya virus ranging from 98 to 100%. Conclusion: In Madagascar, Ae. albopictus has extended its geographical distribution whereas, Ae. aegypti has become rare, contrasting with what was previously observed. Changes are predominantly driven by human activities and the rainfall regime that provide suitable breeding sites for the highly anthropophilic mosquito Ae. albopictus. Moreover, these populations were found to be highly susceptible to chikungunya virus. In the light of this study, Ae. albopictus may have been involved in the recent outbreaks of chikungunya and dengue epidemics in Madagascar, and consequently, control measures should be promoted to limit its current expansion. [less ▲]

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See detailConception architecturale et développement durable. Atelier LL55.
Reiter, Sigrid ULg; Marique, Anne-Françoise ULg

Conference given outside the academic context (2012)

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See detailLa Carte des Sols de la Belgique, outil d'estimation de la pression urbanistique sur les sols
Legrain, Xavier ULg; Michel, Brieuc ULg; Bock, Laurent ULg et al

Conference (2012, March 20)

Ces dernières décennies, des pressions de tout ordre ont induit une forte expansion de l’urbanisation en Europe, à laquelle la Belgique n’échappe pas. L’imperméabilisation des sols a par ailleurs été ... [more ▼]

Ces dernières décennies, des pressions de tout ordre ont induit une forte expansion de l’urbanisation en Europe, à laquelle la Belgique n’échappe pas. L’imperméabilisation des sols a par ailleurs été identifiée comme une des principales menaces pesant sur eux. Au-delà du constat de l’évolution des surfaces artificialisées en Wallonie, l’objectif de cette étude est d’identifier les sols les plus soumis à ce phénomène. L’élaboration de la Carte Numérique des Sols de Wallonie (CNSW) – à partir d’un document historique, la Carte des Sols de la Belgique levée à grande échelle entre 1947 et 1991 – et de la Carte Numérique d’Occupation des Sols de Wallonie ouvre des perspectives intéressantes à ce sujet. Plus spécifiquement, l’utilisation de cartes d’aptitude des sols pour l’agriculture, dérivées de la CNSW, met en évidence l’impact de l’artificialisation sur la réserve en sols de meilleure potentialité agricole (figure 1). Cette dernière a diminué de 5 % à l’échelle de la Wallonie suite à l’artificialisation des sols ces 60 dernières années. La réalité est plus contrastée à l’échelle locale. La moitié des 262 communes wallonnes se situe en deçà, tandis que d’autres ont perdu (du point de vue agricole) jusqu’à 50 % de leurs meilleurs sols, par ailleurs initialement fortement présents sur leur territoire. Autre constat : si la moitié des communes subit une artificialisation uniforme de ses sols, 20 % d’entre elles voient leurs meilleurs sols préférentiellement artificialisés par rapport à ceux de potentialité agricole moindre.Une analyse spatiale fine à plus grande échelle (figure 2) ouvre la voie à la compréhension des phénomènes en jeu et in fine à l’élaboration de recommandations face à la concurrence inévitable entre deux fonctions essentielles des sols : la production agricole et le support des activités humaines. [less ▲]

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See detailQuestions à Claude Romano
Dewalque, Arnaud ULg

Conference (2012, March 20)

Texte de mon intervention lors de la table-ronde autour de l'ouvrage de Claude Romano, "Au coeur de la raison, la phénoménologie" (Paris, Gallimard, 2010). Sont discutés le concept de "phénoménologie", l ... [more ▼]

Texte de mon intervention lors de la table-ronde autour de l'ouvrage de Claude Romano, "Au coeur de la raison, la phénoménologie" (Paris, Gallimard, 2010). Sont discutés le concept de "phénoménologie", l'opposition internalisme/externalisme et l'idée du caractère herméneutique de la phénoménologie. [less ▲]

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See detailRadical coupling of polymers formed by cobalt-mediated radical polymerization
Debuigne, Antoine ULg; Hurtgen, Marie ULg; Jérôme, Christine ULg et al

in Matyjaszewski, Krzysztof; Sumerlin, Brent; Tsarevsky, Nicolas V. (Eds.) Progress in controlled radical polymerization: mechanisms and techniques (2012)

Considerable progress has been recently made in cobalt-mediated radical polymerization (CMRP), a controlled radical polymerization system based on the temporary deactivation of the polymer chains by a ... [more ▼]

Considerable progress has been recently made in cobalt-mediated radical polymerization (CMRP), a controlled radical polymerization system based on the temporary deactivation of the polymer chains by a cobalt complex, like the improvement of the mechanistic understanding, the extension to a range of monomers and the preparation of novel architectures. However, the real breakthrough in this field concerns the development of efficient radical coupling methods for polymer precursors preformed by CMRP. This book chapter aims to describe the general principle and main characteristics of such radical coupling techniques involving dienes, nitrones, fullerenes or carbon nanotubes. Well-defined and complex architectures obtained by these techniques are provided in order to illustrate their potential for macromolecular engineering. [less ▲]

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See detailLa finance à découvert : journalisme d'investigation et sciences sociales
Geuens, Geoffrey ULg

Scientific conference (2012, March 20)

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See detailConstraints on the Parental Melts of Enriched Shergottites from Image Analysis and High Pressure Experiments
Collinet, Max ULg; Medard, Etienne; Devouard, Bertrand et al

Poster (2012, March 20)

Martian basalts can be classified in at least two geochemically different families: enriched and depleted shergottites. Enriched shergottites are characterized by higher incompatible element ... [more ▼]

Martian basalts can be classified in at least two geochemically different families: enriched and depleted shergottites. Enriched shergottites are characterized by higher incompatible element concentrations and initial 87Sr/86Sr and lower initial 143Nd/144Nd and 176Hf/177Hf than depleted shergottites. It is now generally admitted that shergottites result from the melting of at least two distinct mantle reservoirs. Some of the olivine-phyric shergottites (either depleted or enriched), the most magnesian Martian basalts, could represent primitive melts, which are of considerable interest to constrain mantle sources. Two depleted olivine-phyric shergottites, Yamato 980459 and Nothwest Africa (NWA) 5789, are in equilibrium with their most magnesian olivine and their bulk rock compositions are inferred to represent primitive melts. Larkman Nunatak 06319 and NWA 1068, the most magnesian enriched basalts, have bulk Mg# that are too high to be in equilibrium with their olivine megacryst cores. Parental melt compositions have been estimated by subtracting the most magnesian olivine from the bulk rock composition, assuming that olivine megacrysts have partially accumulated. However, because this technique does not account for the actual petrography of these meteorites, we used image analysis to study these rocks history, reconstruct their parent magma and understand the nature of oli-vine megacrysts. Our image analysis results are supported by a series of high-pressure experiments performed on LAR 06319 bulk rock composition to test if it could represent a primitive melt, and understand its crystallization history. [less ▲]

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See detailSOUTHERN BLUES NIGHT Heerlen, Hollande) 2012
Sacré, Robert ULg

E-print/Working paper (2012)

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See detailDegradation mechanisms of Prussian blue pigments in paint layers
Samain, Louise ULg

Doctoral thesis (2012)

Prussian blue is a modern synthetic pigment discovered in Berlin at the beginning of the eighteenth century. Prussian blue is a hydrated iron(III) hexacyanoferrate(II) complex and its color results from ... [more ▼]

Prussian blue is a modern synthetic pigment discovered in Berlin at the beginning of the eighteenth century. Prussian blue is a hydrated iron(III) hexacyanoferrate(II) complex and its color results from an intervalence charge transfer between the iron(II) and iron(III) ions when light is absorbed at ca. 700 nm. Because of both its highly intense color and its low cost, Prussian blue enjoyed immediate popularity among artists and was widely used as a pigment in paintings until the 1970's. However, the permanence of Prussian blue had already been questioned by the mid-eighteenth century, because it exhibits a tendency to fade in light and to turn green. The preparative methods were rapidly recognized as a contributory factor in the fading of the pigment. The main objective of this thesis is the identification of the degradation mechanisms of Prussian blue pigments in paint layers. Prussian blue was synthesized according to both ancient and modern preparation methods. A thorough analysis of the pigments revealed a dependency upon the type of synthesis, the crystallite size, and vacancy content, all properties that influence the local electronic and structural configurations of the iron ions in Prussian blue. The presence of nanocrystalline ferrihydrite as an undesirable iron containing reaction product was identified in Prussian blue pigments prepared according to eighteenth-century recipes. Discoloration upon light exposure in Prussian blue paint layers was induced by accelerated ageing. Pure Prussian blue painted in a dark shade is extremely light fast but fades when either painted in a lighter shade or mixed with white pigments. The fading of Prussian blue was attributed to a reduction of the iron(III) ions at the surface of the paint layer. A partial oxidation of Prussian blue in the entire paint layer was also observed. The analysis of works of art containing Prussian blue confirmed the combined oxidation and reduction of Prussian blue iron ions upon ageing. The study of alteration mechanisms in a painting pigment is essential both for conservation and historical studies in order to best preserve our cultural and artistic heritage with respect to an artist’s original intentions. [less ▲]

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See detailA Two Parameter Kinematic Theory for the Shear Behavior of Deep Beams
Mihaylov, Boyan ULg; Bentz, Evan; Collins, Michael

Conference (2012, March 19)

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See detailDrowsiness monitoring: a matter of life and death !
Wertz, Jérôme ULg; François, Clémentine ULg; Verly, Jacques ULg

Conference (2012, March 19)

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See detailRossano Rosi: triangle amoureux et paternité
Demoulin, Laurent ULg

E-print/Working paper (2012)

Compte rendu du roman de Rossano Rosi Stabat Pater paru aux Impressions nouvelles en mars 2012.

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See detailStrategic Bypass Deterrence
Bloch, Francis; Gautier, Axel ULg

Conference (2012, March 17)

In liberalized network industries, entrants can either compete for service using the existing infrastructure (access) or deploy their own infrastructure capacity (bypass). In this paper, we demonstrate ... [more ▼]

In liberalized network industries, entrants can either compete for service using the existing infrastructure (access) or deploy their own infrastructure capacity (bypass). In this paper, we demonstrate that, under the threat of bypass, the access price set by an unregulated and vertically integrated incumbent is compatible with productive efficiency. This means that the entrant bypasses the existing infrastructure only if it can produces the network input more efficiently. The incumbent lowers the access price compared to the ex-post efficient level to strategically deter inefficient bypass by the entrant. Accordingly, from a productive efficiency point of view, there is no need to regulate access prices when the entrant has the option to bypass. Despite that, we show that restricting the possibilities of access might be profitable for consumers. [less ▲]

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