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See detailTable Ronde autour de « La Séquence Rouge Italienne », Cahiers du GRM, II
Cavazzini, Andrea ULg; Bolmain, Thomas ULg; Carlino, Fabrizio et al

Scientific conference (2012, March 29)

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See detailLa transgression de la norme dans la religion grecque antique : le cas de l'impiété (asebeia)
Delli Pizzi, Aurian ULg

Conference (2012, March 29)

Présentation diachronique du concept d'impiété dans la religion grecque antique

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See detailDisulfide bond scrambling in partially reduced and alkylated peptides revealed by Ion Mobility Mass Spectrometry
Echterbille, Julien ULg; Quinton, Loïc ULg; De Pauw, Edwin ULg

Poster (2012, March 29)

Animal venoms are mainly composed of peptide toxins, which are highly structured by many disulfide bridges. In these toxins, disulfides play different major roles such as increasing the toxins efficiency ... [more ▼]

Animal venoms are mainly composed of peptide toxins, which are highly structured by many disulfide bridges. In these toxins, disulfides play different major roles such as increasing the toxins efficiency by lowering their immunogenicity or providing the adequate conformation to efficiently bind to the biological receptor. Peptide sequencing followed by determination of the cysteine pairings is still challenging and, therefore, an important step in structural analysis. This work was, in its beginning, focused on the development of ion mobility (IMS) based methodology used to assign disulfides. The strategy relies on the analysis of partially reduced/alkylated disulfide containing peptides. The resulting mixture is analyzed by ion mobility, followed by MS/MS acquisition on each mobility resolved species. Surprisingly, first investigations revealed, after partial reduction, a disulfide rearrangement phenomenon. Indeed, some of the cystein pairings were not those expected to be. These experiments were conducted on ¿-CnI and ¿-GI toxins purified from the venoms of Conus consors and Conus geographus marine snails, respectively. Each toxin contains four cysteines linked together with two disulfide bridges. Peptides were partially reduced by an excess of dithiothreitol and then alkylated by a large excess of iodoacetamide. The resulting mixture was purified on a microcolumn before being analyzed by nanoESI-Synapt-G2. Fragmentation was performed after the mobility cell, to obtain specific fragments of each species. Each toxin partially reduced/alkylated results, theoretically, in a mixture of fully oxidized (two disulfides oxidized), fully reduced (two disulfides reduced) and partially reduced forms (one of the two disulfides reduced). Thanks to the mass shift created by the alkylation, an isolation of the species which m/z ratio corresponds to one disulfide reduced and alkylated has been done in the quadrupole before the mobility separation. The arrival time distribution of triply charged ions reveals the presence of different species (4 in the case of ¿-GI and 2 for ¿-CnI), characterized by different relative cross sections in the gas-phase. As ion mobility resolved species give characteristic fragments upon fragmentation (after IMS), we were able to identify a scrambling of the disulfides (isomerization). In simple words, other disulfide bonds than expected ones were characterized. We suppose that the scrambling phenomenon occurs in solution,during the reduction step, since the alkylation cannot avoid rearrangement. The method is now being applied to more complex systems containing 3 or 4 disulfide bridges. The influence of the charge state on the mobility separation is systematically analyzed in terms of structural implications. [less ▲]

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See detailThe central region of quasars seen with gravitational microlensing
Sluse, Dominique ULg

Scientific conference (2012, March 29)

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See detailGlobal imbalances, Exchange Rates and Economic Growth
Artige, Lionel ULg; Cavenaile, Laurent

Conference (2012, March 29)

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See detailNeuromorphic reinforcement learning
Dethier, Julie ULg; Ernst, Damien; Sepulchre, Rodolphe

Conference (2012, March 29)

Living organisms are able to successfully perform challeng- ing tasks such as perception, classification, association, and control. In hope for similar successes in artificial systems, neuromorphic ... [more ▼]

Living organisms are able to successfully perform challeng- ing tasks such as perception, classification, association, and control. In hope for similar successes in artificial systems, neuromorphic engineering uses neurophysiological models of perception and information processing in biological sys- tems to emulate their functions but also resemble their struc- ture [1]. In this abstract, we focus on the basal ganglia (BG), brain region in control of primitive functions of the nervous system, and specifically on their involvement in action selec- tion and reinforcement learning (RL). We hypothesize that neuromorphic-inspired systems will greatly benefit the RL community. [less ▲]

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See detailLe problème de l'analyse psychique: enjeu et intérêt de l'approche brentanienne
Dewalque, Arnaud ULg

Scientific conference (2012, March 29)

Le but de l’exposé est double. Il s’agira, d’une part, de mettre en lumière le développement d’une théorie de l’analyse psychique dans l’école de Franz Brentano et, d’autre part, de tirer quelques ... [more ▼]

Le but de l’exposé est double. Il s’agira, d’une part, de mettre en lumière le développement d’une théorie de l’analyse psychique dans l’école de Franz Brentano et, d’autre part, de tirer quelques implications générales de cette théorie. Dans la partie introductive de l’exposé, on commencera par rattacher la question de la méthode en psychologie au problème de l’analyse, qui concerne la possibilité de décomposer la vie psychique en parties. Quelles sont les parties constitutives du mental ? Et quelle méthode d’investigation requièrent-elles ? On rappellera que, sur ces questions, la psychologie scientifique naissante a été assez largement divisée entre un sensualisme à la Ernst Mach, qui identifie les éléments psychiques aux sensations, et un intentionalisme inspiré de Brentano, qui met en avant la notion d’acte intentionnel. Or, il y a des raisons de penser que la séparation même de ces deux approches, qui perdure encore aujourd’hui, fait obstacle à une théorie unifiée des états mentaux, en particulier perceptuels. Dans la deuxième partie de l’exposé, on suggérera qu’une bonne manière de lever cet obstacle consiste à adopter une théorie fine de l’analyse psychique, susceptible de répondre aux questions suivantes : de quel type méréologique sont les parties constitutives d’un état mental ? Sont-elles « créées » ou seulement « découvertes » par l’analyse psychique ? Et comment s’articulent-elles les unes aux autres ? On examinera alors la théorie de l’analyse de Brentano, dont la particularité est d’admettre des « parties distinctionnelles » ou des « moments abstraits » à l’intérieur même des phénomènes psychiques indivisibles. On s’appuiera principalement, à cet égard, sur la Deskriptive Psychologie de 1887-91, mais on considérera également le développement du problème de l’analyse chez certains brentaniens, notamment Hans Cornelius (« Über Verschmelzung und Analyse », 1892-93) et Alexius Meinong (« Beiträge zur Theorie der psychischen Analyse », 1894). Enfin, dans la dernière partie de l’exposé, on tirera quelques conclusions d’allure très générale, destinées à montrer la pertinence de l’approche analytique brentanienne pour certains débats actuels en philosophie de l’esprit. [less ▲]

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See detailDelayed graft function does not harm the future of donation-after- cardiac-death kidney transplants
LeDinh, H; WEEKERS, Laurent ULg; BONVOISIN, Catherine ULg et al

Conference (2012, March 29)

Introduction: Delayed graft function (DGF) occurs more frequently in kidney transplants from donation after cardiac death (DCD) than from donation after brain death (DBD). We investigated the effect of ... [more ▼]

Introduction: Delayed graft function (DGF) occurs more frequently in kidney transplants from donation after cardiac death (DCD) than from donation after brain death (DBD). We investigated the effect of DGF on post-transplant outcomes in controlled DCD kidney grafts. Patients and Methods: This single-center retrospective study recruited 80 controlled DCD kidney allo- grafts which have been performed at the University Hospital of Sart Tilman, University of Liège, from Jan 2005 to Dec 2011. Results: Mean patient follow-up was 28.5 months. No primary non-function grafts were encountered. DGF rate was 36%. Overall graft survivals between groups with and without DGF were 92.4% and 95.1% at 1 year, 92.4% and 91.7% at 3 years, and 84.7% and 91.7% at 5 years (p=ns), respectively. Patients with and without DGF had the same survival rates at the corresponding time points (92.4% and 97.1%, 92.4% and 93.7%, and 84.7% and 93.7%, p=ns, respectively). Estimated glomerular filtration rate (eGFR) was significantly lower in DGF group compared to non-DGF group at hospital discharge (29 vs 42 ml/min, p=0.001) and up to 1 year post-transplant (46 vs 53 ml/min, p=0.045), but the differ- ence disappeared afterwards (50 vs 48 ml/min at 3 years, and 54 vs 53 ml/min at 5 years, p=ns). DGF did not increase the risk of acute rejection or surgical complications. 29.6% of recipients with DGF de- veloped acute rejection (biopsy-proven rejection and clinically suspected rejection) compared with 29.2% of recipients without DGF (p=ns). The rate of all surgical complications was 33.3% and 25% in recipients with and without DGF (p=ns). However, DGF prolonged significantly the length of hospitaliza- tion in DGF than non-DGF group (18.9 vs 13 days, p=0.000). Donor BMI 􏰤 30 kg/m2􏰁􏰀􏰚􏰌􏰈􏰏􏰥􏰏􏰌􏰝􏰣􏰀􏰕􏰉􏰂􏰀􏰤 30 kg/m2 and pre-transplant dialysis duration increased the risk of DGF in a multivariate logistic regression analysis. Conclusions: Apart from longer hospital stay, DGF had no deleterious impact on the future of DCD kidney allografts. Comparable graft and patient survival, renal function, rejection rate and surgical com- plications were observed between groups with and without DGF. [less ▲]

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See detailConclusions générales et perspectives
Seron, Vincent ULg

Conference (2012, March 29)

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See detailNuclear Trade Regulation in the European Union
Michel, Quentin ULg

Learning material (2012)

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See detailContentieux administratif : power point 2012
Durviaux, Ann-Lawrence ULg

Learning material (2012)

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See detail1D many-body quantum transport of Bose-Einstein condensates : a truncated Wigner approach
Dujardin, Julien ULg; Argüelles Parra, Arturo ULg; Schlagheck, Peter ULg

Poster (2012, March 29)

We calculate the transport properties of an ultracold gas of Bose- Einstein condensed atoms that is coupled from a magnetic trap into a one-dimensional waveguide. A central aim of such guided atom lasers ... [more ▼]

We calculate the transport properties of an ultracold gas of Bose- Einstein condensed atoms that is coupled from a magnetic trap into a one-dimensional waveguide. A central aim of such guided atom lasers is to study the role of atom-atom interaction in many-body transport processes across finite scattering regions within the waveguide resembling tunnel junctions and quantum dots. Our numerical approach to solve this many-body scattering problem is based on a home-made theory where the boundaries of the system are simulating an open system enabling us to calulate observable in the steady-state regime such as density, current, transmission. The results are compared to the mean-field regime. [less ▲]

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See detailDo common principles underlie the representation of order in STM and numerical judgment tasks?
Attout, Lucie ULg; Majerus, Steve ULg

Conference (2012, March 29)

Although many studies have explored magnitude effects in numerical cognition, the representation of order information has received only limited interest. We explored the hypothesis that common abstract ... [more ▼]

Although many studies have explored magnitude effects in numerical cognition, the representation of order information has received only limited interest. We explored the hypothesis that common abstract ordinal representations underlie the representation of order information across different domains. We tested this hypothesis by determining the similarity of distance effects in short-term memory (STM) order probe recognition (did ‘8’ occur before ‘5’ in the list ‘3, 6, 5, 4, 8, 7’ presented a few seconds ago?) and in order judgment tasks (does ‘1’ occur before ‘2’), both numerical and alphabetical stimuli were used. In numerical cognition, adjacent numbers are typically judged more slowly than more distant numbers. In fifty healthy adults, we observed significant distance effects across all tasks: in the order judgment tasks, adjacent numbers/letters were judged more slowly than more distant numbers/letters; in the STM tasks, order recognition was slowed for stimuli stemming from adjacent positions in the STM list as compared to stimuli stemming from more distant positions. Regression slopes for distance effects were identical across the different tasks and conditions. Furthermore, the size of distance effects correlated significantly across tasks, except for the order judgment task with numerical stimuli. We will discuss the implications of these results for a hypothetical common representational system of order information in STM and numerical cognition. [less ▲]

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See detailCASUS 2012 - Contentieux administratif
Durviaux, Ann-Lawrence ULg; Fisse, Damien ULg

Learning material (2012)

analyse de cas

Detailed reference viewed: 67 (5 ULg)
See detailImproved Finite Element Solvers for the Helmholtz Equation at High Frequencies
Geuzaine, Christophe ULg

Scientific conference (2012, March 29)

Detailed reference viewed: 31 (2 ULg)
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See detailComment peut-on parler des littératures francophones. À propos de Vies et mort de la francophonie
Provenzano, François ULg

Conference given outside the academic context (2012)

Detailed reference viewed: 16 (2 ULg)