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See detailINTERRATER AGREEMENT OF CLINICAL TESTS/SIGNS USED TO IDENTIFY PATIENTS WITH LUMBAR FUNCTIONAL INSTABILITY
Demoulin, Christophe ULg; Emmanuel, P.; DISTREE, Vincent ULg et al

in Journal of Orthopaedic & Sports Physical Therapy (2012, October), 42(10), 57

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See detailDosimetry for 6-[18F]Fluoro-L-DOPA in Humans Based on Biodistribution in Mice
Bretin, Florian ULg; Warnock, Geoffrey ULg; Bahri, Mohamed Ali ULg et al

Poster (2012, October)

Aim. The objective of this work was to estimate human dosimetry for 6-[18F]Fluoro-L-DOPA (F-DOPA) from biodistribution in mice, obtained from organ harvesting at different time points and from a hybrid ... [more ▼]

Aim. The objective of this work was to estimate human dosimetry for 6-[18F]Fluoro-L-DOPA (F-DOPA) from biodistribution in mice, obtained from organ harvesting at different time points and from a hybrid method combining dynamic PET followed by organ harvesting. Materials and methods. The tissue distribution of F-DOPA over time was determined in isoflurane-anaesthetized mice. Radioassay was performed on harvested organs at 2, 5, 10, 30, 60 and 120 minutes post administration (n = 5 at each time point). Dynamic PET images were acquired in list-mode with a Siemens FOCUS 120 microPET for 120 minutes after injection and followed by radioassay of harvested organs (n = 4). List-mode data were histogrammed in 6*5s, 6*10s, 3*20s, 5*30s, 5*60s, 8*150s, 6*300s, 6*600s 3D sinograms. Final images were obtained using filtered backprojection with correction for all physical effects except for scatter. Attenuation correction resulted from a pre-injection transmission scan with a cobalt-57 point source. Organs were manually delineated. The organ time-activity-curves (TACs) from both methods were extrapolated from a simulated 35 g standard mouse to a 70 kg standard male human using a technique based on organ to bodyweight ratios. A bladder voiding scenario was used to simulate excretion every 2 h. The absorbed doses in major human organs were calculated using the extrapolated TACs with the commercially available software OLINDA/EXM (Version 1.1). Results. The extrapolated organ activity curves obtained using the harvesting and imaging methods showed a high correlation (r = 0.94 ± 0.05, p < 0.001). However, TACs from PET alone under- or overestimated the activity in individual organs in contrast to TACs obtained using the cross-calibration of the PET data with the activity in post-scan dissected organs. Those organs in the excretion pathways, comprising bladder wall, kidneys and liver, received the highest organ doses. The total body absorbed dose was 0.0118 mGy/MBq for both the imaging based and harvesting based methods. The effective dose was 0.0193 mSv/MBq for the hybrid imaging-harvesting technique and 0.0189 mSv/MBq for the pure harvesting technique. Conclusion. The doses obtained agreed well with the few results available in the literature. The hybrid technique combining dynamic PET scanning followed by organ harvesting appeared to be a good alternative to the gold standard ex vivo radioassay method. It is much faster and minimizes the effect of some weakness of the pure imaging technique, such as partial volume effect. [less ▲]

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See detailNurse educator's competencies: facing the challenges
Dury, Cécile ULg

Conference (2012, October)

This symposium proposes presentations related to nurse educators competencies and the challenges links to their new roles. The evolution of the nurses training at the European level asks the teacher to ... [more ▼]

This symposium proposes presentations related to nurse educators competencies and the challenges links to their new roles. The evolution of the nurses training at the European level asks the teacher to develop high-level disciplinary skills but also educational skills. There are lots of challenges to develop nurse educator competencies. The role of the teachers is not any more to transmit disciplinary knowledge but to become experts in group management, colleagues teamwork, reflective practice, and construction of active learning situations in a socio constructivist model. These changes of roles also have an impact on the professional identity of the teachers. The various presentations will approach successively these ideas: 1. A proposal for a Competencies Benchmarking of Nurse Educators The aim of this presentation is to characterize the nursing teachers concepts on their professionalism,roles, competences and their identities construction. 2. Educational knowledge in teaching in nursing This presentation examine the teachers conceptions about teaching nursing and professional knowledge about teaching in higher education. 3. Construction of teaching/learning to care from the perspective of nursing teacher This presentation analyses the facilities and difficulties of nurse teacher in their role. 4. The OSCE, an educational project who support the development of the nurse teacher competencies A model for the implementation of a reflexive approach for the nursing training: challenges for the nurse teachers [less ▲]

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See detailLittle by Little. Expansions of Nanoscience and Emerging Technologies
van Lente, Harro; Coenen, Christopher; Fleischer, Torsten et al

Book published by IOS Press (2012)

Little by little, nanotechnology has emerged amid enormous anticipations and fantastic promises of new materials, aspiring to manipulate our world “atom by atom.” While these grand visions continue to ... [more ▼]

Little by little, nanotechnology has emerged amid enormous anticipations and fantastic promises of new materials, aspiring to manipulate our world “atom by atom.” While these grand visions continue to capture the imaginations of various audiences—and continue to be contested, as well—nanotechnology has developed into more than that. During the last two decades, many research programs and industrial R&D expenditures have resulted in actual products and tangible innovations. Nanotechnology, it seems, is expanding. But what does it mean to say that nanotechnology is expanding? [less ▲]

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See detailTraduire les droits
Pagnoulle, Christine ULg

Book published by L3 (2012)

This book brings together ten contributions in French on various aspects oflegal translation, bridging not only languages but legal systems and within the same systems different cultual approaches.

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See detail1D Organization of ZnO and TiO2 nanoparticles toward advanced photonic and photocatalytic materials
Kinadjian, Natacha ULg; Achard, Marie-France; Julian-Lopez, Beatriz et al

Poster (2012, October)

Nowadays Chemist are request to construct more and more complex architectures bearing multifunctionalities enable to respond to external stimuli. The construction of such complex architectures will be ... [more ▼]

Nowadays Chemist are request to construct more and more complex architectures bearing multifunctionalities enable to respond to external stimuli. The construction of such complex architectures will be addressed through strong interplay in chemical science, as proposed recently with the concept of integrative Chemistry.[1] We synthesized PVA/ZnO-nanorods composite fibers using co-axial flux extrusion.[2] These fibers exhibit higher anisotropic photonic properties, both in absorption and emission, as a result of the collective alignment of the ZnO nanorods along the main axis of the PVA fiber. This photonic anisotropy is triggered by a synergistic interaction between the PVA matrix, stretched above Tg, and cooled down under strain. Compared with non-elongated fibers that present an isotropic emission, composite fibers previously submitted to a tensile stress absorb selectively UV emission when the polarized laser beam is parallel to the main axis of the fiber. In addition, their photolumincescence is also anisotropic, with a waveguide behavior along the main axis of the fiber. Mechanical properties of these composite fibers are also drastically improved, compared with pure PVA fibers: the longitudinal Young modulus of these fibers is increased from 2 to 6 GPa upon ZnO addition, a value similar to those already observed for composite fibers, prepared either with carbon nanotubes, or Vanadium Oxide macroscopic fibers. [1] N. Brun, S. Ungureanu, H. Deleuze and R. Backov. Chem. Soc. Rev., 2011, 40, 771 [2] Kinadjian, N., Achard, M.-F., Julián-López, B., Maugey, M., Poulin, P., Prouzet, E. and Backov, R. (2012). Adv. Funct. Mater.. doi: 10.1002/adfm.201200360 [less ▲]

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See detailGestion de la diversité en milieu hospitalier
Cornet, Annie ULg

Speech/Talk (2012)

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See detailIn Ovo PET Imaging Of A Human Colorectal Carcinoma Model In Chicken Chorioallantoic Membrane
Warnock, Geoffrey ULg; Turtoi, Andrei ULg; Blomme, Arnaud ULg et al

Poster (2012, October)

Aim. The objective of this study was to use in vivo PET/CT imaging as a validation tool for a novel human colorectal carcinoma model being developed in chicken chorioallantoic membrane (CAM). For this ... [more ▼]

Aim. The objective of this study was to use in vivo PET/CT imaging as a validation tool for a novel human colorectal carcinoma model being developed in chicken chorioallantoic membrane (CAM). For this initial pilot study a cell line modeling colon cancer was selected and imaged using [18F]fluorodeoxyglucose (FDG). <br />Materials and methods. A window was made in the shell of fertilized chicken eggs and 3x106 SW1222 human colorectal carcinoma cells were implanted at day 10 post-fertilization. On day 17 the shell window was enlarged to allow direct injection of FDG (12.2 ± 4.5 MBq/egg) into a CAM blood vessel. During injection the egg was warmed on a heating pad. A mixture of ketamine/medetomidine (50 :1 mg/ml, 0.2 ml/egg) was injected into the albumin in some eggs to assess the effect of anesthesia. After FDG injection the egg was returned to the incubator for a 45 min uptake period before imaging. Imaging was performed on a Siemens Focus 120 microPET with structural CT on a General Electric eXplore CT120. A Minerve cell system allowed reproducible positioning between modalities. PET data was acquired in list mode before histogramming into a single 10 min frame for reconstruction using a 3D maximum a posteriori (MAP) method with all corrections except scatter. A standard 100 µm (theoretical) image resolution protocol (70 kV, 50 mA, 32 ms, 220 views) was used to obtain structural CT data. Image coregistration was performed in PMOD version 3.3. In a separate egg, the influence of added contrast on the CT data was investigated by adding iodinated contrast agent (Iobitridol 35 mgI/ml) to the albumin. <br />Results. FDG uptake was clear in chick and tumor, with notably high uptake at the major joints. Tumors were identified by localization of FDG uptake on the surface of the CAM. A lack of soft tissue contrast between tumor, CAM and albumin made precise structural identification of the tumor difficult. Anesthesia was crucial to image quality in both PET and CT. CT contrast between the soft tissues of the chick and surrounding albumin/structures was improved by addition of contrast agent. <br />Conclusion. For the first time we demonstrate successful imaging of FDG uptake in a human colorectal carcinoma chicken CAM model in ovo. Methods to improve structural data are under investigation and will be used in further studies. With such improvement, this model could be of great value to PET oncology imaging. [less ▲]

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See detailFamilial Pituitary Syndromes
Beckers, Albert ULg

in 12th ESE PostGraduate Course in Clinical Endocrinology - Abstract book (2012, October)

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See detailThe earthquake sedimentary record in the the Sea of Marmara, Turkey
Hubert, Aurelia ULg; Drab, Loreen; Schmidt, Sabine et al

Conference (2012, October)

The submarine part of the North Anatolian Fault (NAF) is a very significant hazard for the 12 million people living in Istanbul (Turkey). An accurate seismic risk assessment necessitates ... [more ▼]

The submarine part of the North Anatolian Fault (NAF) is a very significant hazard for the 12 million people living in Istanbul (Turkey). An accurate seismic risk assessment necessitates paleoseismological data, which can be retrieved in the Marmara Sea by using sedimentary cores. We present here a record of turbidites obtained in cores spanning the Tekirdag ̆ Basin, the Western High, the Central Basin, and the Cinarcik Basin. In the Tekirdag and Western High the turbidites are synchronous pointing to shaking by earthquakes as a triggering mechanism. Generally seismoturbidites in the Marmara Sea are distinguished from other turbidites based in their large extension, their particular granulometric and their particular geochemical characteristics. The 210Pb and 137Cs radionucleides measurements have also shown that the M=7.4 1912 Mürefte earthquake and the M=7.3 1894 Prince's Island earthquake have left a distinctive sedimentary imprint at the top of the studied cores. The chronology of other seismoturbidites is built combining radiocarbon dating and secular variation patterns of paleo-declination and paleo-inclination. Finally the obtained record is compared to the historical seismicity record. [less ▲]

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See detailEpidemiology and genetics of FIPA
Beckers, Albert ULg

in 15th annual Canadian Society of Endocrinology and metabolism - Abstract book (2012, October)

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See detailL’appareillage orthétique distal du membre inférieur chez le patient neurologique
DOUCHAMPS, Frédéric ULg; Kaux, Jean-François ULg; WANG, François-Charles ULg

in Lettre du Neurologue (La) : le Courrier du Spécialiste (2012), XVI(8), 268-274

La prescription d’une orthèse doit tenir compte: • de la spasticité des muscles tibial postérieur et triceps sural (échelle d’Ashworth) ; • de la force des releveurs (échelle de Lovett) ; • de la statique ... [more ▼]

La prescription d’une orthèse doit tenir compte: • de la spasticité des muscles tibial postérieur et triceps sural (échelle d’Ashworth) ; • de la force des releveurs (échelle de Lovett) ; • de la statique plantaire (pied varus et/ou talus en phase d’appui) ; • de l’âge et du niveau d’activité (sédentaire, sportif) ; • de l’attente des patients. [less ▲]

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See detailCadre institutionnel et juridique de la gestion de crise
Bair, Jean-Pol ULg; Thiry, Aline ULg

in Brunet, Sébastien; Fallon, Catherine; Ozer, Pierre (Eds.) et al Articuler risques, planification d'urgence et gestion de crise (2012)

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See detailCumulative time in band: glycemic level, variability and patient outcome vs. mortality
Penning, Sophie ULg; Signal, Matthew; PREISER, Jean-Charles ULg et al

Poster (2012, October)

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See detailConclusion générale
Thiry, Aline ULg; Fallon, Catherine ULg

in Brunet, Sébastien; Fallon, Catherine; Ozer, Pierre (Eds.) et al Articuler risques, planification d'urgence et gestion de crise (2012)

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See detailLow density structures in the local universe. I. Diffuse agglomerates of galaxies
Karachentsev, I.D.; Karachentseva, V.E.; Melnyk, Olga et al

in Astrophysical Bulletin (2012), 67(4), 353-361

This paper is the first of a series considering the properties of distribution of nearby galaxies in the low density regions. Among 7596 galaxies with radial velocities V_{LG}<3500 km/s, absolute ... [more ▼]

This paper is the first of a series considering the properties of distribution of nearby galaxies in the low density regions. Among 7596 galaxies with radial velocities V_{LG}<3500 km/s, absolute magnitudes M_K<-18.4^m$, and Galactic latitudes |b| >15 degr there are 3168 field galaxies (i.e. 42%) that do not belong to pairs, groups or clusters in the Local universe. Applying to this sample the percolation method with a radius of r_0=2.8 Mpc, we found 226 diffuse agglomerates with n>=4 number of members. The structures of eight most populated objects among them (n>=25) are discussed. These non-virialized agglomerates are characterized by a median dispersion of radial velocities of about 170 km/s, the linear size of around 6 Mpc, integral K-band luminosity of 3*10^{11} L_sun, and a formal virial-mass-to-luminosity ratio of about 700 M_sun/L_sun. The mean density contrast for the considered agglomerates is only <Delta n/\bar{n}\gtrsim 5, and their crossing time is about 30-40 Gyr. [less ▲]

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See detailA design for living: metaleptic devices and trends of gnostic imagination in contemporary science-fiction
Claisse, Frédéric ULg

Conference (2012, October)

As a narrative pattern and a cultural motif, the confusion between fictional worlds and reality traditionally leads to metaphysical arguments about liberty and destiny. Despite their drawing heavily on ... [more ▼]

As a narrative pattern and a cultural motif, the confusion between fictional worlds and reality traditionally leads to metaphysical arguments about liberty and destiny. Despite their drawing heavily on scientific imagination and technoscientific artefacts, science fiction movies exploring that theme never really broke with the way it has been treated since Calderon de la Barca’s Life is a dream: the hero’s quest leads him to doubt his own identity and dispute the ontological status of the world he lives in, leaving him and the viewer perplexed as to the ultimate nature of things. Yet, in the last fifteen years, an increasing number of science-fiction movies renewed that interrogation, notably by placing the issue of design at the centre of the plot: fictional worlds are not only denounced as fictional, but also shown as works in progress, literally rebuilt according to the plan of not-so-hidden designers acting as demiurges. In Dark City, Vanilla Sky or, more recently, Inception and The Adjustment Bureau, the emphasis on design and architecture together with the use of computational metaphors result in the promotion of one particular world to the status of “reference” universe, to be held as more “real” than other, fabricated and computed worlds made accessible by sophisticated devices operating as metaleptic instruments (such as Neo’s cable plug or the “bio-ports” in ExistenZ). This paper wishes to explore this shift towards “gnostic", Matrix-like science-fictional narratives, particularly in relation to the dramatic development of networking and surveillance capabilities that occurred during the same period. [less ▲]

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