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See detailA new Splitting-based Displacement Prediction Approach for Location-Based Services
Daoud, Mohammad Sh; Ayesh, Aladdin; Hopgood, Adrian ULiege et al

in 2011 IEEE International Conference on Systems, Man and Cybernetics (SMC 2011) (2011)

In location-based services (LBSs), the service is provided based on the users' locations through location determination and mobility realization. Several location prediction models have been proposed to ... [more ▼]

In location-based services (LBSs), the service is provided based on the users' locations through location determination and mobility realization. Several location prediction models have been proposed to enhance and increase the relevance of the information retrieved by users of mobile information systems, but none of them studied the relationship between accuracy rate of prediction and the performance of the model in terms of consuming resources and constraints of mobile devices. Most of the current location prediction research is focused on generalized location models, where the geographic extent is divided into regular-shape cells. These models are not suitable for certain LBSs where the objectives are to compute and present on-road services. One such technique is the Prediction Location Model (PLM), which deals with inner cell structure. The PLM technique suffers from memory usage and poor accuracy. The main goal of this paper is to propose a new path prediction technique for Location-Based Services. The new approach is competitive and more efficient compared to PLM regarding measurements such as accuracy rate of location prediction and memory usage. [less ▲]

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See detailÊtre jeune et Franstalig à Gand. Enquête sociolinguistique exploratoire au sein de la communauté des francophones de Flandre.
Dassargues, Alix ULiege

Master's dissertation (2011)

Ce travail explore le champ des attitudes et des représentations linguistiques de francophones de Flandre et plus particulièrement celles de jeunes (15-25ans) francophones gantois. L’analyse de données ... [more ▼]

Ce travail explore le champ des attitudes et des représentations linguistiques de francophones de Flandre et plus particulièrement celles de jeunes (15-25ans) francophones gantois. L’analyse de données quantitatives recueillies par un questionnaire écrit et de données qualitatives provenant d’interviews et d’observations participatives a permis de mettre au jour une série de comportements sociolinguistiques originaux. Ces nouveaux apports ont, en outre, été confrontés aux résultats d’une étude sociolinguistique effectuée par Yolande Van den Branden (UGent) sur une population semblable trente ans auparavant. La comparaison des données qualitatives des deux enquêtes met ainsi en évidence la lente et profonde évolution de la situation du français en Flandre entre 1983 et 2011. [less ▲]

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See detailThe 5-HT1A agonism potential of substituted-piperazine-ethyl-amide derivatives is conserved in the hexyl homologues: molecular modeling and pharmacological evaluation
Dilly, Sébastien ULiege; Scuvée-Moreau, Jacqueline ULiege; Wouters, Johan et al

in Journal of Chemical Information & Modeling (2011), 51(11), 2961-2966

In a series of carboxamide and sulphonamide alkyl (ethyl to hexyl) piperazine analogues, although the size of the linker is very different, ethyl and hexyl derivatives possess a high affinity for 5-HT1A ... [more ▼]

In a series of carboxamide and sulphonamide alkyl (ethyl to hexyl) piperazine analogues, although the size of the linker is very different, ethyl and hexyl derivatives possess a high affinity for 5-HT1A receptors. Docking studies clearly show that hexyl and ethyl compounds favourably interact with the binding site of the active conformation of 5-HT1A receptors, thus confirming a possible agonist profile. This activity is effectively detected in electrophysiological experiments in which all four compounds inhibit the activity of rat dorsal raphe serotonergic neurons. [less ▲]

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See detailCompte rendu de Enzyklopädie des Mittelalters, éd. G. MELVILLE, M. STAUB
Masson, Christophe ULiege

in Moyen Age (Le) (2011), CXVII

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See detailLe coma psychogène
DEBABECHE, Cécile ULiege; PIETTE, Catherine ULiege; Ansseau, Marc ULiege et al

in Acta Psychiatrica Belgica (2011), 111(3), 20-25

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See detailComment j'explore les hypoglycémies chez l'enfant : à propos de deux cas
HARVENGT, Julie ULiege; DEBRAY, François-Guillaume ULiege; LEBRETHON, Marie-Christine ULiege et al

in Revue Médicale de Liège (2011), 66(12), 631-635

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See detailSite-specific Septoria Leaf Blotch Risk Assessment in Winter Wheat using Weather-Radar Rainfall Estimates
Mahtour, Abdeslam ULiege; El Jarroudi, Moussa ULiege; Delobbe, Laurent et al

in Plant Disease (2011), 10.1094/PDIS-07-10-0482

The Septoria leaf blotch prediction model PROCULTURE was used to assess the impact on simulated infection rates when using rainfall estimated by radar instead of rain gauge measurements. When comparing ... [more ▼]

The Septoria leaf blotch prediction model PROCULTURE was used to assess the impact on simulated infection rates when using rainfall estimated by radar instead of rain gauge measurements. When comparing infection events simulated by PROCULTURE using radar- and gauge-derived data, the probability of detection (PODs) of infection events was high (0.83 on average), and the false alarm ratio (FARs) of infection events was not negligible (0.24 on average). For most stations, FARso of infection events decreased to 0 and PODso increased (0.85 on average) when the model outputs for both datasets were compared against visual observations of disease symptoms. An analysis of 148 infection events over three years at four locations showed no significant difference in the number of infection events of simulations using either dataset, indicating that, for a given location, radar estimates were as reliable as rain gauges for predicting infection events. Radar also provided better estimates of rainfall occurrence over a continuous space than weather station networks. The high spatial resolution provides radar with an important advantage that could significantly improve existing warning systems. [less ▲]

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See detailTowards a New Canadianness: Re(-)Membering Canada in Lawrence Hill’s Any Known Blood (1997) and David Chariandy’s Soucouyant (2007)
Mergeai, Mathilde ULiege

in Canada and Beyond: A Journal of Canadian Literary and Cultural Studies (2011), 1(1-2), 83-103

This article examines the representation of Canadian multiculturalism in Lawrence Hill’s Any Known Blood (1997) and David Chariandy’s Soucouyant (2007). I argue that these novels can be regarded as ... [more ▼]

This article examines the representation of Canadian multiculturalism in Lawrence Hill’s Any Known Blood (1997) and David Chariandy’s Soucouyant (2007). I argue that these novels can be regarded as revisions of Canada’s official policy towards minorities, because they both creatively rewrite silenced parts of national history, and attempt to remap the connections between Canada and the world beyond the national frontiers. Hill’s and Chariandy’s revision of the past and redrawing of the present are made particularly clear in their novels through the representation of Canadian space, more specifically in their distancing from the image of urban centres as areas of cosmopolitanism. This idea of setting the narrative in conventionally Canadian (rural) topographies is also a way of locating their Black characters in a geographical environment traditionally seen as White, which thus allows the writers to question the very elements constitutive of Canadian identity and, by extension, of the Canadian nation. [less ▲]

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See detailSmall molecule inhibitors of peptidoglycan synthesis targeting the lipid II precursor.
Derouaux, Adeline ULiege; Turk, Samo; Olrichs, Nick K et al

in Biochemical Pharmacology (2011), 81(9), 1098-105

Bacterial peptidoglycan glycosyltransferases (GTs) of family 51 catalyze the polymerization of the lipid II precursor into linear peptidoglycan strands. This activity is essential to bacteria and ... [more ▼]

Bacterial peptidoglycan glycosyltransferases (GTs) of family 51 catalyze the polymerization of the lipid II precursor into linear peptidoglycan strands. This activity is essential to bacteria and represents a validated target for the development of new antibacterials. Application of structure-based virtual screening to the National Cancer Institute library using eHits program and the structure of the glycosyltransferase domain of the Staphylococcus aureus penicillin-binding protein 2 resulted in the identification of two small molecules analogues 5, a 2-[1-[(2-chlorophenyl)methyl]-2-methyl-5-methylsulfanylindol-3-yl]ethanamine and 5b, a 2-[1-[(3,4-dichlorophenyl)methyl]-2-methyl-5-methylsulfanylindol-3-yl]ethanamine that exhibit antibacterial activity against several Gram-positive bacteria but were less active on Gram-negative bacteria. The two compounds inhibit the activity of five GTs in the micromolar range. Investigation of the mechanism of action shows that the compounds specifically target peptidoglycan synthesis. Unexpectedly, despite the fact that the compounds were predicted to bind to the GT active site, compound 5b was found to interact with the lipid II substrate via the pyrophosphate motif. In addition, this compound showed a negatively charged phospholipid-dependent membrane depolarization and disruption activity. These small molecules are promising leads for the development of more active and specific compounds to target the essential GT step in cell wall synthesis. [less ▲]

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See detailEvolution and predictive factors of relapse in ulcerative colitis patients treated with mesalazine after a first course of corticosteroids.
Bello, C.; Belaiche, Jacques ULiege; Louis, Edouard ULiege et al

in Journal of Crohn's & colitis (2011), 5(3), 196-202

INTRODUCTION: Mesalazine remains the first line treatment for the induction and the maintenance of remission in mild to moderate ulcerative colitis (UC). Its efficacy as a maintenance treatment after a ... [more ▼]

INTRODUCTION: Mesalazine remains the first line treatment for the induction and the maintenance of remission in mild to moderate ulcerative colitis (UC). Its efficacy as a maintenance treatment after a first flare treated with corticosteroids has not been specifically studied. The aims of our work were to study a cohort of UC patients treated with mesalazine after a course of oral systemic corticosteroids and to identify predictive factors of relapse and of colectomy. MATERIAL AND METHOD: We studied retrospectively a cohort of 143 UC patients, who never received immunosuppressive drugs, and treated for the first time with oral corticosteroids for a flare. Among patients responding to corticosteroids, we studied the group treated by mesalazine after the flare. RESULTS: Fifty% (n=52) achieved a complete clinical remission with steroid weaning. In this group, 67% (n=35) received oral mesalazine. Seventy-five % of patients treated by mesalazine relapsed (median 29 months, range: 1-156). Fourteen % required a colectomy (median 11 months, range: 1-24). Kaplan Meier curve showed a relapse rate and a colectomy rate over one year of 26% and 11% respectively. In multivariate analysis, male gender and short duration of disease were predictive factors of the time-to-relapse. No factor was predictive of time-to-colectomy. CONCLUSION: Maintenance efficacy of mesalazine over one year after a first course of corticosteroids for a disease flare is reasonably high. The longer-term relapse rate becomes higher in male patients with a short disease duration. An immunosuppressive treatment could be discussed in case of further relapse despite improved medication-adherence. Medication-adherence should first be assessed and promoted. An immunosuppressive treatment could be discussed in case of further relapse despite improved medication-adherence. [less ▲]

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See detailResults of the 2nd part Scientific Workshop of the ECCO. II: Measures and markers of prediction to achieve, detect, and monitor intestinal healing in inflammatory bowel disease.
Daperno, Marco; Castiglione, Fabiana; de Ridder, Lissy et al

in Journal of Crohn's & colitis (2011), 5(5), 484-98

The healing of the intestine is becoming an important objective in the management of inflammatory bowel diseases. It is associated with improved disease outcome. Therefore the assessment of this healing ... [more ▼]

The healing of the intestine is becoming an important objective in the management of inflammatory bowel diseases. It is associated with improved disease outcome. Therefore the assessment of this healing both in clinical studies and routine practice is a key issue. Endoscopy for the colon and terminal ileum and computerized tomography or magnetic resonance imaging for the small bowel are the most direct ways to evaluate intestinal healing. However, there are many unsolved questions about the definition and the precise assessment of intestinal healing using these endoscopic and imaging techniques. Furthermore, these are relatively invasive and expensive procedures that may be inadequate for regular patients' monitoring. Therefore, biomarkers such as C-reactive protein and fecal calprotectin have been proposed as surrogate markers for intestinal healing. Nevertheless, the sensitivity and specificity of these markers for the prediction of healing may be insufficient for routine practice. New stool, blood or intestinal biomarkers are currently studied and may improve our ability to monitor intestinal healing in the future. [less ▲]

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See detailPsychosocial risk and protective factors of secondary school dropout in Luxembourg: the protocol of an exploratory case-control study.
Esch, Pascale; Bocquet, Valery; Pull, Charles et al

in BMC Public Health (2011), 11

BACKGROUND: In Luxembourg, the extensive phenomenon of school dropout is a prime policy concern in the light of individual, social and economic consequences. Although the authorities report an overall ... [more ▼]

BACKGROUND: In Luxembourg, the extensive phenomenon of school dropout is a prime policy concern in the light of individual, social and economic consequences. Although the authorities report an overall decrease of the national dropout rate, the proportion of early school leavers who remain without any specific occupation is still alarming. Therefore, this study intends a shift of focus from system-inherent to individual factors, including mental health and family correlates, to provide a more comprehensive analysis of the dropout phenomenon. METHODS/DESIGN: The objectives of this study are to investigate the type and prevalence of psychiatric disorders among school dropouts and to compare the findings with those by a matched control group of regularly enrolled students. Furthermore, family variables and socioeconomic status will be analysed, as they are factors likely to interfere with both educational attainment and mental health. A trained psychologist will use structured interviews and self-report forms to investigate for mental health issues, information on schooling, socioeconomic situation and family life. Controls will be matched for gender, age, school type and educational grade. DISCUSSION: As school dropouts face a serious risk of long term professional and social marginalization, there is an evident need for action. Identifying psychosocial risk and protective factors of school dropout will deliver solid insight on how to conceive public health strategies for young people who may need a more customized support to carry out their academic potential. TRIAL REGISTRATION: ClinicalTrials.gov Identifier: NCT01354236. [less ▲]

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See detailPrise en charge de la douleur chronique en Belgique : passé, présent et futur
Berquin, Anne; FAYMONVILLE, Marie-Elisabeth ULiege; Deseure, Kristof et al

Report (2011)

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See detailSurgical hand antisepsis in veterinary practice: evaluation of soap scrubs and alcohol based rub techniques
Verwilghen, Denis ULiege; Mainil, Jacques ULiege; Mastrocicco, Emilie et al

in Veterinary Journal (2011), 190(3), 372-377

Recent evidence shows hydro-alcoholic solutions are more efficient than traditional medicinated soaps in the presurgical hand antisepsis of human surgeons. However, little veterinary literature is ... [more ▼]

Recent evidence shows hydro-alcoholic solutions are more efficient than traditional medicinated soaps in the presurgical hand antisepsis of human surgeons. However, little veterinary literature is available on the subject. The aims of this study were to compare the efficiency of medicinated soaps and a hydro-alcoholic solution prior to surgery using an in use testing method in a veterinary setting. A preliminary trial was performed that compared the mean Log10 number of bacterial colony forming units (CFU) and the reduction factors (RF) between 2 five-minute hand-scrubbing sessions using different soaps (povidone iodine (PVP) and chlorhexidine gluconate (CHX)) and the 1.5-min application of a hydro-alcoholic rub (Sterillium). A clinical in use trial comparing mean log10 number of bacterial CFU’s and RF for Sterillium and CHX soap was performed in a surgical set-up. Sampling was performed using finger printing on agar plates. Sterillium and CHX had a similar immediate effect, although the sustained effect was significantly better for Sterillium. PVP showed a significantly lower immediate and sustained effect. Sterillium showed good efficiency in the clinical trial. This study shows that, as previously reported for human medicine, Sterillium can safely be considered as an attractive alternative method for surgical hand antisepsis in a veterinary surgical setting. [less ▲]

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See detailSynthesis by sol-gel process of visible light sensitive-TiO2 for the degradation of pollutants and microorganisms
Tasseroul, Ludivine ULiege; Lambert, Stéphanie ULiege; Páez Martínez, Carlos ULiege et al

Poster (2011)

Since the discovery of photocatalytic decomposition of water on TiO2 electrodes by Fujishima and Honda [1], heterogenous photocatalysis has been widely studied for environmental applications ... [more ▼]

Since the discovery of photocatalytic decomposition of water on TiO2 electrodes by Fujishima and Honda [1], heterogenous photocatalysis has been widely studied for environmental applications. Photocatalytic processes are new technologies for waste water treatment because new compounds (alkanes, pesticides, dyes, etc.) in effluents are not readily degraded by the conventional treatments [2]. Oxidative processes can completely destroy organic pollutants [3] or microorganisms (bacteria, viruses, fungi, etc.) [4,5]. At this moment, the commercial Degussa P25 is the mostly used photocatalyst. Nevertheless, it requires UV light to be activated, that is why scientists try to activate TiO2 under visible light. The aim of this study is to synthesize photocatalysts activated by visible light and to evaluate their activity for the degradation of pollutants and microorganisms. The sol-gel process allows the direct introduction of visible light sensitive species like porphyrins inside the TiO2 matrix during the synthesis [6]. Two tetracarboxyphenyl porphyrins are synthesized for the sensitization of TiO2 to visible light : the metal free tetracarboxyphenyl porphyrin and the nickel tetracarboxyphenyl porphyrin. These porphyrins are characterized by 1H NMR, FT-IR and UV/Vis spectroscopies. They are introduced during the sol-gel synthesis of TiO2 matrix. Diffuse reflectance and FT-IR spectroscopies are used to ensure that porphyrins are incorporated inside the matrix of TiO2. Indeed, characteristic porphyrins peaks appear on spectra. The cristallinity and specific surfaces of catalysts are also determined by XRD and nitrogen adsorption-desorption measurements respectively. The depolluting efficiency of photocatalysts is evaluated for the degradation in water of p-nitrophenol, which is listed as one of the 114 organic pollutants by the Environmental Protection Agency in the US. After 6 h under visible light, 40 % of p-nitrophenol are degraded with some catalysts. The activity is influenced by i) the presence of porphyrins : the photoactivity increases with the amount of porphyrins ; ii) the nature of porphyrins : nickel porphyrins are more active than free metal porphyrins ; and iii) the crystallinity of catalysts : amorphous catalysts are less active than crystallized samples. The photocatalysts with the highest degradation rating of dyes will be selected for the degradation in water of Escherichia coli and Lactobacillus acidophilus. [1] A. Fujishima, K. Honda, Nature 238, 37-38 (1972) [2] P. Gogate, A. Pandit, Advances in Environmental Research 8, 501-551 (2004). [3] D. Chen, A. Ray, Water Research 32, 3223-3234 (1998) [4] R. Watts, S. Kong, M. Orr, G. Miller, B. Henry, Water Research 29, 95-100 (1995). [5] J. Hong, M. Otaki, Journal of Bioscience and Bioengineering 101, 185-189 (2006). [6] C. Wang, J. Li, G. Mele, G.M. Yang, F.-X. Zhang, L. Palmisano, G. Vasapollo, Applied catalysis 78, 218-226 (2007). [less ▲]

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See detailDispatcher-assisted telephone cardiopulmonary resuscitation using a French-language compression-only protocol in volunteers with or without prior life support training: A randomized trial.
Ghuysen, Alexandre ULiege; Collas, D.; Stipulante, Samuel ULiege et al

in Resuscitation (2011)

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to ... [more ▼]

OBJECTIVES: Due to the recent interest in hands-only protocols for dispatcher-assisted cardiopulmonary resuscitation (CPR) and the lack of any validated algorithms in French, our primary objective was to evaluate a new French-language protocol in terms of its efficacy to help previously untrained volunteers in performing basic life support efforts of appropriate quality, and secondarily to investigate its potential utility in subjects with previous training. METHODS: Untrained volunteers were recruited among adults in a public movie centre and previously trained volunteers among undergraduate nursing students. Participants were randomly assigned to 'phone CPR' versus 'no phone CPR' by drawing sets of envelopes. Primary outcome measures were the results of the Cardiff evaluation test; the secondary measures were global scoring of a complete 5min period of CPR, in a manikin model of cardiac arrest. RESULTS: Out of 146 volunteers assessed for eligibility, 36 previously untrained candidates declined participation. 110 participants, distributed into four groups, completed the study: the previously untrained non-guided group (group A, n=30), the previously untrained guided group (group B, n=30), the previously trained non-guided group (group C, n=25) and the previously trained guided group (group D, n=25). Results of the Cardiff test and global evaluation of CPR performance revealed a significant improvement in group B as compared with group A, approaching the level of the group C. Previously trained guided bystanders had the best CPR scores, notably because of an improvement in the quality of airway management. CONCLUSION: When used by dispatchers, this new French-language algorithm offers the opportunity to help previously untrained bystanders initiate CPR. The same protocol may serve to guide volunteers with prior basic life support training to reach their best CPR performance. [less ▲]

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See detailEvolution de la pauvreté au Vietnam : quelques réflexions
Mai, Lan Phuong ULiege; Lebailly, Philippe ULiege; Nguyen Mau, Dung

Conference (2011)

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