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See detailSubject-specific cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: animal experiments and proof of concept.
Chase, J Geoffrey; Lambermont, Bernard ULg; Starfinger, Christina et al

in Physiological Measurement (2011), 32(1), 65-82

A cardiovascular system (CVS) model and parameter identification method have previously been validated for identifying different cardiac and circulatory dysfunctions in simulation and using porcine models ... [more ▼]

A cardiovascular system (CVS) model and parameter identification method have previously been validated for identifying different cardiac and circulatory dysfunctions in simulation and using porcine models of pulmonary embolism, hypovolemia with PEEP titrations and induced endotoxic shock. However, these studies required both left and right heart catheters to collect the data required for subject-specific monitoring and diagnosis-a maximally invasive data set in a critical care setting although it does occur in practice. Hence, use of this model-based diagnostic would require significant additional invasive sensors for some subjects, which is unacceptable in some, if not all, cases. The main goal of this study is to prove the concept of using only measurements from one side of the heart (right) in a 'minimal' data set to identify an effective patient-specific model that can capture key clinical trends in endotoxic shock. This research extends existing methods to a reduced and minimal data set requiring only a single catheter and reducing the risk of infection and other complications-a very common, typical situation in critical care patients, particularly after cardiac surgery. The extended methods and assumptions that found it are developed and presented in a case study for the patient-specific parameter identification of pig-specific parameters in an animal model of induced endotoxic shock. This case study is used to define the impact of this minimal data set on the quality and accuracy of the model application for monitoring, detecting and diagnosing septic shock. Six anesthetized healthy pigs weighing 20-30 kg received a 0.5 mg kg(-1) endotoxin infusion over a period of 30 min from T0 to T30. For this research, only right heart measurements were obtained. Errors for the identified model are within 8% when the model is identified from data, re-simulated and then compared to the experimentally measured data, including measurements not used in the identification process for validation. Importantly, all identified parameter trends match physiologically and clinically and experimentally expected changes, indicating that no diagnostic power is lost. This work represents a further with human subjects validation for this model-based approach to cardiovascular diagnosis and therapy guidance in monitoring endotoxic disease states. The results and methods obtained can be readily extended from this case study to the other animal model results presented previously. Overall, these results provide further support for prospective, proof of concept clinical testing with humans. [less ▲]

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See detailEffect of pH and water activity on the growth limits of Listeria monocytogenes in a cheese matrix at two contamination levels.
Schvartzman Echenique, Maria Sol ULg; Belessi, C.; Butler, F. et al

in Journal of food protection (2011), 74(11), 1805-13

Listeria monocytogenes can proliferate at the beginning of cheesemaking as the conditions favor growth. The objective of this study was to establish the growth limits of L. monocytogenes in a cheese ... [more ▼]

Listeria monocytogenes can proliferate at the beginning of cheesemaking as the conditions favor growth. The objective of this study was to establish the growth limits of L. monocytogenes in a cheese matrix, in case of potential contamination of the milk prior to cheese manufacture. A semisoft laboratory scale model cheese system was made at different initial pH and water activity (a(w)) levels with a mix of two strains of L. monocytogenes. A factorial design of five pH values (5.6 to 6.5), four a(w) values (0.938 to 0.96), and two L. monocytogenes inoculation levels (1 to 20 CFU/ml and 500 to 1,000 CFU/ml) was carried out. Each combination was evaluated in six independent replicates. In order to determine if there was a dominant strain, isolated colonies from the cheeses were analyzed by pulsed-field gel electrophoresis. The data relating to growth initiation were fitted to a logistic regression model. The a(w) of milk influenced the probability of growth initiation of L. monocytogenes at both low and high contamination levels. The pH, at the concentrations tested, had a lower effect on the probability of growth initiation. At pH 6.5 and a(w) of 0.99 for low contamination levels and pH 6.5 and a(w) of 0.97 for high contamination levels, increases in population of up to 4 and 2 log were observed at low and high contamination levels, respectively. This shows that if conditions are favorable for growth initiation at the early stages of the cheesemaking process, contamination of milk, even with low numbers, could lead to L. monocytogenes populations that exceed the European Union's microbiological limit of 100 CFU/g of cheese. [less ▲]

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See detailDuden - Deutsches Universalwörterbuch
Auberle, Anette; Eickhoff, Birgit; Haller-Wolf, Angelika et al

Book published by Dudenverlag - 7ème éd. (2011)

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See detailMalignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3+CD8+CD4- T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues.
Dewals, Benjamin G ULg; Vanderplasschen, Alain ULg

in Veterinary research (2011), 42(1), 95

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross ... [more ▼]

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. WD-MCF can be reproduced experimentally in rabbits. In a previous report, we demonstrated that WD-MCF induced by AlHV-1 is associated with a severe proliferation of CD8+ T cells in the lymphoid tissues. Here, we further studied the mononuclear leukocytic populations in both the lymphoid (throughout the infection and at time of euthanasia) and non-lymphoid (at time of euthanasia) organs during WD-MCF induced experimentally in rabbits. To reach that goal, we performed multi-colour flow cytometry stainings. The results obtained demonstrate that the development of WD-MCF correlates in peripheral blood with a severe increase of CD8+ cell percentages; and that CD3+CD8+CD4- T cells were the predominant cell type in both lymphoid and non-lymphoid organs at time of euthanasia. Further characterization of the mononuclear leukocytes isolated from both lymphoid and non-lymphoid tissues revealed that the CD8+ T cells express high levels of the activation markers CD25 and CD44, produce high amount of gamma-interferon (IFN-gamma) and perforin, and showed a reduction of interleukin-2 (IL-2) gene expression. These data demonstrate that the development of WD-MCF is associated with the expansion and infiltration of activated and cytotoxic CD3+CD8+CD4- T cells secreting high amount of IFN-gamma but low IL-2. [less ▲]

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See detailBeyond matching on the mean in developmental disabilities research
Facon, Bruno; Magis, David ULg; Belmont, John M

in Research in Developmental Disabilities (2011), 32

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but ... [more ▼]

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but not the homogeneity of their variances or the shapes of their distributions. In the present paper, it is argued that group matching can go seriously wrong unless it directly confronts the distributional concerns by the use of well-known statistical indices and very simple graphical displays of the distributions. The question of the equivalency of item response profiles is also addressed since two participants or two groups of participants can obtain the same overall score on the matching variable by passing different items. In this case, the matching cannot be considered satisfactory because of poor concordance between the molar (overall score) and molecular (item scores) levels of matching. Angoff's Delta plot method, a statistical approach for detecting differential item functioning across small groups is described. It is promising as a simple way to prove whole test/individual item correspondence and, in addition, a useful tool for making post-hoc statistical analyses at the item level on the dependant variables. [less ▲]

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See detailVoice related complaints in the pediatric population
Verduyckt, Ingrid; Remacle, Marc; Jamart, Jacques et al

in Journal of Voice (2011), 25(3), 373-380

Subjective evaluation of the voice by the patient is routinely assessed in the adult dysphonic population; this Q6 is, however, not the case in the pediatric population. There were three objectives of ... [more ▼]

Subjective evaluation of the voice by the patient is routinely assessed in the adult dysphonic population; this Q6 is, however, not the case in the pediatric population. There were three objectives of this study: the first goal was to study the ability of children aged 5–13 years to express themselves about physical, emotional, and sociofunctional aspects of their voice. The second goal was to explore if specific voice-related complaints were expressed by dysphonic children as compared with normophonic children. The third goal was to compare the dysphonic children’s voice-related complaints with those of their mothers. The overall objective was to set the grounds for the elaboration of a standardized questionnaire in French concerning subjective evaluation of voice in children. Twenty-five dysphonic children with vocal complaint (15 nodules, one polyp, one microweb, eight unspecified) and 55 normophonic children aged 5–13 years were interviewed. The interviews were semistructured based on a canvas of voice-related questions. The dysphonic children’s mothers were interviewed with the mean of a written questionnaire and were invited to discuss their answers orally with the examiner. The results were analyzed ualitatively and statistically.AChi-square test and the Fisher’s test were used to analyze the differences between the complaints expressed by the dysphonic and the normophonic children, and a binomial test was used to compare the children’s answers with their mothers’ answers. The qualitative analysis of the interviews suggests that children are capable of reflecting over their ownvoice and of giving autonomous information about different aspects of their voice. It also appeared that voice is a complex phenomenon and that it needs to be clearly and cautiously defined to the children.We identified 27 different complaints related to the voice, out of which 17 were significantly more expressed by dysphonic than by normophonic children (P < 0.05). Three of the 27 identified complaints show significant discordances between the mothers and the dysphonic children. The results suggest that children are capable of making a subjective and autonomous evaluation of their voice and that dysphonic children experience significantly more voicerelated discomfort than nondysphonic children. The complaints expressed by the dysphonic children and their mothers are not all in concordance. The main conclusion is that a standardized subjective evaluation of the voice, not only by the parents but also by the child itself, would be relevant in the assessment of pediatric dysphonia. [less ▲]

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See detailAgro-pedological Assessment of the Traditional Yuanyang Rice Terraces of Yunnan Province, China
Colinet, Gilles ULg; Koulos, Keiko; Wu, Bozhi et al

in Journal of Resources and Ecology (2011), 2(4), 353-361

As a contribution to a long-term evaluation of the sustainability of agro-ecosystems in the Yuanyang rice terraces, this paper reviews the bio-physical environment of the terraced landscape in a small ... [more ▼]

As a contribution to a long-term evaluation of the sustainability of agro-ecosystems in the Yuanyang rice terraces, this paper reviews the bio-physical environment of the terraced landscape in a small catchment around Qingkou village and assesses soil fertility in the village crop growing area. A soillandscape organization pattern was developed using a geomorphopedological approach. Anthropogenic, climatic and topographic factors were identified as the main soil forming factors. Soil capability and associated edaphic constraints were assessed and the main soil types were identified and classified using FAO protocols. Spatial patterns of soil fertility appear quite homogeneous. Soils are acid and cation exchange capacity and nutrient reserves are generally low. The agro-ecosystem has largely been developed by the Hani population. This agro-ecosystem has succeeded in maintaining a relatively dynamic nutrient circulation system. Current research is focusing on: (i) the evaluation of the representativeness of the studied area compared to the whole terraced system in the Yuanyang terraced landscape; (ii) measurements of nutrients flows at the field scale; (iii) the effects of soil properties on crop yields; and (iv) up-scaling field levels results to larger spatial units. [less ▲]

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See detailProblèmes du bilinguisme dans l'Antiquité gréco-romaine
Rochette, Bruno ULg

in Genet, Jean-Philippe (Ed.) Langues et histoire. Actes du colloque de l'Ecole doctorale d'histoire de Paris 1 INHA, 20 et 21 octobre 2006 (2011)

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See detailDiscovering the lichen diversity of a remote tropical island: working list of species collected on Reunion (Mascarene archipelago, Indian Ocean)
Sérusiaux, Emmanuël ULg; van den Boom, Pieter P. G.; Brand, Maarten et al

in Herzogia (2011), 24(2), 325-349

463 lichen taxa are reported from the island of Reunion (Mascarene archipelago) in the Indian Ocean. This report is based on extensive collections recently made by the authors or hosted in B and LG. A ... [more ▼]

463 lichen taxa are reported from the island of Reunion (Mascarene archipelago) in the Indian Ocean. This report is based on extensive collections recently made by the authors or hosted in B and LG. A total of c. 600 species is estimated for the number of lichenized fungi present on the island; although this is a low figure for a varied tropi- cal area, this is plausible due to its small size and remoteness. The significance of the lichen diversity of the island lays in its endemics, which need further study for a reliable assessment, and in the occurrence of a poorly known southern hemisphere element (“austral” species). The discovery of the following in Reunion is of special interest as it considerably enlarges their distribution range: Anzia corallophora, Caloplaca caesiosorediata, Coccocarpia delicatula, Fuscopannaria praetermissa, Gomphillus morchelloides, G. pedersenii, Gyalideopsis bispora, Heterodermia koyana, Hypotrachyna evansii, Lithogyalideopsis zeylandica, Lobaria asperula, Megaloblastenia marginiflexa var. dimota, Menegazzia capitata, Myeloconis erumpens and Pannaria squamulosa. [less ▲]

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See detailSTRATEGY FOR ASSESSING IMPACTS OF THYROID DISRUPTING CHEMICALS IN TELEOSTEANS
Schnitzler, Joseph ULg; Klaren, Peter; Celis, Niko et al

in Organohalogen Compounds (2011)

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See detailOverview of CO2 dynamics within sea ice
Delille, Bruno ULg; Geilfus, Nicolas-Xavier ULg; Vancoppenolle, M. et al

Conference (2011)

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See detailPost-mortem examination and laboratory-based analysis for the diagnosis of bovine tuberculosis among dairy cattle in Ecuador
Proano-Perez, F.; Benitez-Ortiz, Washington; Desmecht, Daniel ULg et al

in Preventive Veterinary Medicine (2011), 101(1-2), 65-72

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See detail2D-Vertical Model for Free Surface Incompressible Flows: Validation and Applications
Detrembleur, Sylvain; Dewals, Benjamin ULg; Pirotton, Michel ULg

in Proc. 34th IAHR World Congress - Balance and Uncertainty (2011)

Efficient design of hydraulic structures such as weirs and bottom outlets requires a detailed description of the complex turbulent flows occurring on these structures. Compared to laboratory experiments ... [more ▼]

Efficient design of hydraulic structures such as weirs and bottom outlets requires a detailed description of the complex turbulent flows occurring on these structures. Compared to laboratory experiments, numerical modeling offers more flexibility and cost-effectiveness to test different designs. The non-hydrostatic 2D-vertical model presented here solves the RANS equations for incompressible flows in the vertical plane. It is based on the projection method for pressure-velocity coupling, while free surface tracking is conducted by means of the level set technique and Sussman’s velocity extension algorithm. It enables to predict accurately the flow pattern in the vertical plane and deals with multiple interfaces (jets, drops…). The solver has been validated for both steady and unsteady free surface flows, based on theoretical and experimental data. The paper will detail the application of the model to a pressurized flow and to a sloshing tank. [less ▲]

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See detailEnd of life care in the operating room for non-heart-beating donors: organization at the University Hospital of Liege.
JORIS, Jean ULg; KABA, Abdourahmane ULg; LAUWICK, Séverine ULg et al

in Transplantation Proceedings (2011), 43(9), 3441-4

Non-heart-beating (NHB) organ donation has become an alternative source to increase organ supply for transplantation. A NHB donation program was implemented in our institution in 2002. As in many ... [more ▼]

Non-heart-beating (NHB) organ donation has become an alternative source to increase organ supply for transplantation. A NHB donation program was implemented in our institution in 2002. As in many institutions the end of life care of the NHB donor (NHBD) is terminated in the operating room (OR) to reduce warm ischemia time. Herein we have described the organization of end of life care for these patients in our institution, including the problems addressed, the solution proposed, and the remaining issues. Emphasis is given to our protocol elaborated with the different contributors of the chain of the NHB donation program. This protocol specifies the information mandatory in the medical records, the end of life care procedure, the determination of death, and the issue of organ preservation measures before NHBD death. The persisting malaise associated with NHB donation reported by OR nurses is finally documented using an anonymous questionnaire. [less ▲]

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See detailA non-invasive approach to study lifetime exposure and bioaccumulation of PCBs in protected marine mammals: PBPK modeling in harbor porpoises
Weijs, Liesbeth; Covaci, Adrian; Yang, Raymond S. H. et al

in Toxicology and Applied Pharmacology (2011), 256

In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically ... [more ▼]

In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically, these models provide a new, non-destructive tool that enables the integration of biomonitoring activities and in vitro studies. The goals of the present study were firstly to develop PBPK models for several environmental relevant PCB congeners in harbor porpoises (Phocoena phocoena), a species that is sensitive to pollution because of its limited metabolic capacity for pollutant transformation. These models were tested using tissue data of porpoises from the Black Sea. Secondly, the predictive power of the models was investigated for time trends in the PCB concentrations in North Sea harbor porpoises between 1990 and 2008. Thirdly, attempts were made to assess metabolic capacities of harbor porpoises for the investigated PCBs. In general, results show that parameter values from other species (rodents, humans) are not always suitable in marine mammal models, most probably due to differences in physiology and exposure. The PCB 149 levels decrease the fastest in male harbor porpoises from the North Sea in a time period of 18†years, whereas the PCB 101 levels decrease the slowest. According to the models, metabolic breakdown of PCB 118 is probably of lesser importance compared to other elimination pathways. For PCB 101 and 149 however, the presence of their metabolites can be attributed to bioaccumulation of metabolites from the prey and to metabolic breakdown of the parent compounds in the harbor porpoises. [less ▲]

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See detailToothed whales in the northwestern Mediterranean: Insight into their feeding ecology using chemical tracers
Praca, Emilie; Laran, Sophie; Lepoint, Gilles ULg et al

in Marine Pollution Bulletin (2011), 62(5), 1058-1065

Risso’s dolphins, pilot whales and sperm whales rarely strand in the northwestern Mediterranean. Thus, their feeding ecology, through the analysis of stomach contents, is poorly known. The aim of this ... [more ▼]

Risso’s dolphins, pilot whales and sperm whales rarely strand in the northwestern Mediterranean. Thus, their feeding ecology, through the analysis of stomach contents, is poorly known. The aim of this study was to gain further insight into the segregation/superposition of the diet and habitat of Risso’s dolphins, pilot whales and sperm whales using chemical tracers, namely, stable isotopes (d13C, d15N) and orga- nochlorines. Significantly different d15N values were obtained in Risso’s dolphins (11.7 ± 0.7‰), sperm whales (10.8 ± 0.3‰) and pilot whales (9.8 ± 0.3‰), revealing different trophic levels. These differences are presumably due to various proportions of Histioteuthidae cephalopods in each toothed whale’s diet. Similar d13C contents between species indicated long-term habitat superposition or corroborated impor- tant seasonal migrations. Lower congener 180 concentrations (8.20 vs. 21.73 lg.g􏰀1 lw) and higher tDDT/ tPCB ratios (0.93 vs. 0.42) were observed in sperm whales compared with Risso’s dolphins and may indi- cate wider migrations for the former. Therefore, competition between these species seems to depend on different trophic levels and migration patterns. [less ▲]

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See detailDensity functional theory beyond the linear regime: Validating an adiabatic local density approximation
Helbig, N.; Fuks, J. I.; Casula, M. et al

in Physical Review. A (2011), 83

We present a local density approximation (LDA) for one-dimensional (1D) systems interacting via the soft-Coulomb interaction based on quantum Monte Carlo calculations. Results for the ground-state ... [more ▼]

We present a local density approximation (LDA) for one-dimensional (1D) systems interacting via the soft-Coulomb interaction based on quantum Monte Carlo calculations. Results for the ground-state energies and ionization potentials of finite 1D systems show excellent agreement with exact calculations obtained by exploiting the mapping of an N-electron system in d dimensions onto a single electron in N×d dimensions, properly symmetrized by the Young diagrams. We conclude that 1D LDA is of the same quality as its three-dimensional (3D) counterpart, and we infer conclusions about 3D LDA. The linear and nonlinear time-dependent responses of 1D model systems using LDA, exact exchange, and the exact solution are investigated and show very good agreement in both cases, except for the well-known problem of missing double excitations. Consequently, the 3D LDA is expected to be of good quality beyond the linear response. In addition, the 1D LDA should prove useful in modeling the interaction of atoms with strong laser fields, where this specific 1D model is often used. [less ▲]

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See detailGas Sensing with Au-Decorated Carbon Nanotubes
Zanolli, Zeila ULg; Leghrib, Radouane; Felten, Alexandre et al

in ACS Nano (2011), 5(6), 4592-4599

The sensing properties of carbon nanotubes (CNTs) decorated with gold nanopar- ticles have been investigated by means of combined theoretical and experimental approaches. On one hand, first-principles and ... [more ▼]

The sensing properties of carbon nanotubes (CNTs) decorated with gold nanopar- ticles have been investigated by means of combined theoretical and experimental approaches. On one hand, first-principles and nonequilibrium Green's functions techniques give access to the microscopic features of the sensing mechanisms in individual nanotubes, such as electronic charge transfers and quantum conductances. On the other hand, drop coating deposition of carbon nanotubes decorated with gold nanoparticles onto sensor substrates and their characterization in the detection of pollutants such as NO2, CO, and C6H6 provide insight into the sensing ability of nanotube mats. Using the present combined approaches, the improvement in the detection of some specific gases (NO2 and CO) using Au-functionalized nanotubes is explained. However, for other gases such as C6H6, the Au nanoparticles do not seem to play a crucial role in the sensing process when compared with pristine CNTs functionalized with oxygen plasma. Indeed, these different situations can be explained by identifying the relationship between the change of resistance (macroscopic feature) and the shift of the Fermi level (microscopic feature) after gas adsorption. The understanding of the sensing ability at the atomic level opens the way to design new gas sensors and to tune their selectivity by predicting the nature of the metal that is the most appropriate to detect specific molecular species. [less ▲]

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See detailGold(I) complexes bearing mixed-donor ligands derived from N-heterocyclic carbenes
Chia, Eugene Y; Naeem, Saira; Delaude, Lionel ULg et al

in Dalton Transactions (2011), 40(25), 6645-6658

The new 2-phenylthiocarbamoyl-1,3-dimesitylimidazolium inner salt (IMes•CSNPh) reacts with [AuCl(L)] in the presence of NH4PF6 to yield [(L)Au(SCNPh•IMes)]+ (L = PMe3, PPh3, PCy3, CNBut). The carbene ... [more ▼]

The new 2-phenylthiocarbamoyl-1,3-dimesitylimidazolium inner salt (IMes•CSNPh) reacts with [AuCl(L)] in the presence of NH4PF6 to yield [(L)Au(SCNPh•IMes)]+ (L = PMe3, PPh3, PCy3, CNBut). The carbene-containing precursor [(IDip)AuCl] reacts with IMes•CSNPh under the same conditions to afford the complex [(IDip)Au(SCNPh•IMes)] + (IDip = 1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene). Treatment of the diphosphine complex [(dppm)(AuCl)2] with one equivalent of IMes•CSNPh yields the digold metallacycle, [(dppm)Au 2(SCNPh•IMes)]2+, while reaction of [L 2(AuCl)2] with two equivalents of IMes•CSNPh results in [(L2){Au(SCNPh•IMes)}2]2+ (L2 = dppb, dppf, or dppa; dppb = 1,4-bis(diphenylphosphino)butane, dppf = 1,1'-bis(diphenylphosphino)ferrocene, dppa = 1,4- bis(diphenylphosphino)acetylene). The homoleptic complex [Au(SCNPh•IMes) 2]+ is formed on reaction of [AuCl(tht)] (tht = tetrahydrothiophene) with two equivalents of the imidazolium-2- phenylthiocarbamoyl ligand. This product reacts with AgOTf to yield the mixed metal compound [AuAg(SCNPh•IMes)2]2+. Over time, the unusual trimetallic complex [Au(AgOTf)2(SCNPh•IMes) 2]+ is formed. The sulfur-oxygen mixed-donor ligands IMes•COS and SIMes•COS (SIMes = 1,3-bis(2,4,6-trimethylphenyl) imidazolin-2-ylidene) were used to prepare [(L)Au(SOC•IMes)]+ and [(L)Au(SOC•SIMes)]+ from [(L)AuCl] (L = PPh3, CNtBu). The bimetallic examples [(dppf){Au(SOC•IMes)} 2]2+ and [(dppf){Au(SOC•SIMes)}2] 2+ were synthesized from the reaction of [(dppf)(AuCl)2] with the appropriate ligand. Reaction of [(tht)AuCl] with one equivalent of IMes•COS or SIMes•COS yields [Au(SOC•IMes) 2]+ and [Au(SOC•SIMes)2]+, respectively. The compounds [(Ph3P)Au(SCNPh•IMes)]PF 6, [(Cy3P)Au(SCNPh•IMes)]PF6 and [Au(AgOTf)2(SCNPh•IMes)2]OTf were characterized crystallographically. [less ▲]

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