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See detailThe Herschel view of nebulae around evolved massive stars
Vamvatira-Nakou, Chloi ULg; Royer, P.; Hutsemekers, Damien ULg et al

Conference (2011)

The detailed study of the nebulae ejected from Luminous Blue Variables and the circumstellar bubbles around Wolf-Rayet stars, which radiate strongly in the IR due to the heating of dust, is crucial for ... [more ▼]

The detailed study of the nebulae ejected from Luminous Blue Variables and the circumstellar bubbles around Wolf-Rayet stars, which radiate strongly in the IR due to the heating of dust, is crucial for understanding the massive stars evolution. With Herschel, the largest telescope ever flown in space, we are able to study the gas and the dust in these circumstellar environments in the full far-infrared waveband. In the context of 'Mass-loss of Evolved StarS' Herschel guaranteed time key programme, we have obtained imaging and spectroscopic observations of nebulae associated with Luminous Blue Variable and Wolf-Rayet stars using PACS, one of the three instruments onboard Herschel. A description of these observations and first results of the data analysis are presented. [less ▲]

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See detailIdentification and characterization of novel galectin-9 splice variants in endothelial cells
Heusschen, Roy ULg; De Bree, Martijn; Griffioen, Arjan et al

in Cancer Research (2011)

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See detailGenou douloureux de l'enfant sportif
Kaux, Jean-François ULg

Learning material (2011)

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See detailVoice related complaints in the pediatric population
Verduyckt, Ingrid; Remacle, Marc; Jamart, Jacques et al

in Journal of Voice (2011), 25(3), 373-380

Subjective evaluation of the voice by the patient is routinely assessed in the adult dysphonic population; this Q6 is, however, not the case in the pediatric population. There were three objectives of ... [more ▼]

Subjective evaluation of the voice by the patient is routinely assessed in the adult dysphonic population; this Q6 is, however, not the case in the pediatric population. There were three objectives of this study: the first goal was to study the ability of children aged 5–13 years to express themselves about physical, emotional, and sociofunctional aspects of their voice. The second goal was to explore if specific voice-related complaints were expressed by dysphonic children as compared with normophonic children. The third goal was to compare the dysphonic children’s voice-related complaints with those of their mothers. The overall objective was to set the grounds for the elaboration of a standardized questionnaire in French concerning subjective evaluation of voice in children. Twenty-five dysphonic children with vocal complaint (15 nodules, one polyp, one microweb, eight unspecified) and 55 normophonic children aged 5–13 years were interviewed. The interviews were semistructured based on a canvas of voice-related questions. The dysphonic children’s mothers were interviewed with the mean of a written questionnaire and were invited to discuss their answers orally with the examiner. The results were analyzed ualitatively and statistically.AChi-square test and the Fisher’s test were used to analyze the differences between the complaints expressed by the dysphonic and the normophonic children, and a binomial test was used to compare the children’s answers with their mothers’ answers. The qualitative analysis of the interviews suggests that children are capable of reflecting over their ownvoice and of giving autonomous information about different aspects of their voice. It also appeared that voice is a complex phenomenon and that it needs to be clearly and cautiously defined to the children.We identified 27 different complaints related to the voice, out of which 17 were significantly more expressed by dysphonic than by normophonic children (P < 0.05). Three of the 27 identified complaints show significant discordances between the mothers and the dysphonic children. The results suggest that children are capable of making a subjective and autonomous evaluation of their voice and that dysphonic children experience significantly more voicerelated discomfort than nondysphonic children. The complaints expressed by the dysphonic children and their mothers are not all in concordance. The main conclusion is that a standardized subjective evaluation of the voice, not only by the parents but also by the child itself, would be relevant in the assessment of pediatric dysphonia. [less ▲]

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See detailA coupled two-scale computational scheme for the failure of periodic quasi-brittle thin planar shells and its application to masonry
Mercatoris, Benoît ULg; Massart, T. J.

in International Journal for Numerical Methods in Engineering (2011), 85(9), 1177-1206

This paper presents a multi-scale framework for the failure of periodic quasi-brittle thin planar shells. The failure behavior of textured or periodic heterogeneous materials is strongly influenced by ... [more ▼]

This paper presents a multi-scale framework for the failure of periodic quasi-brittle thin planar shells. The failure behavior of textured or periodic heterogeneous materials is strongly influenced by their mesostructure. Their periodicity and the quasi-brittle nature of their constituents result in complex behaviors such as damage-induced anisotropy properties with localization of damage, which are difficult to model by means of macroscopic closed-form constitutive laws. A computational homogenization procedure is used for the in-plane and out-of-plane behavior of such planar shells, and is combined with an acoustic tensor-based failure detection adapted to shell kinematics to detect the structural-scale failure. Based on an assumption of single period failure, the localization of damage at the structural scale is represented by means of mesostructurally informed embedded strong discontinuities incorporated in the macroscopic shell description. A new enhanced scale transition is outlined for shell failure, based on an approximate energy consistency argument to objectively upscale the energy dissipation. The corresponding multi-scale framework results are compared with direct fine-scale modeling results used as a reference for the case of masonry, showing good agreement in terms of the load-bearing capacity, of failure mechanisms and of associated energy dissipation. © 2010 John Wiley & Sons, Ltd. [less ▲]

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See detailInventaire des archives de la Société anonyme métallurgique d'Espérance-Longdoz (1806-1971)
Delvaux, Anne-Catherine ULg

Book published by Archives générales du Royaume (2011)

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See detailRate of Malignancies and Infections in a Large Single Center Cohort of IBD Patients Treated With Thiopurines and Anti-TNF-Antibodies.
Ochsenkühn, T; Steinborn, A; Beigel, F et al

in Journal of Crohn’s and Colitis (2011)

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See detailIs there really an Azores diversity enigma? Insights from the phylogeography of the heather Erica scoparia s.l.
Desamore, Aurélie ULg

Poster (2011)

The Azorean flora, in contrast to that of other archipelagos, is characterized by a paucity of evolutionary radiations and the widespread distribution of most endemics. Several hypotheses, including ... [more ▼]

The Azorean flora, in contrast to that of other archipelagos, is characterized by a paucity of evolutionary radiations and the widespread distribution of most endemics. Several hypotheses, including isolation from the continent, recent age, ecological homogeneity, and limited paleoclimatic variations, have been proposed to account for this pattern. These hypotheses are tested here within the context of the molecular phylogeography of the heather Erica scoparia s.l., a Mediterraneo-Atlantic species complex distributed across Macaronesia, North Africa and southwestern Europe. The marked molecular radiation of this species in the Azores, including an array of single-island endemics, suggests that the apparent homogeneity of the Azorean flora might, in fact, conceal undetected patterns of endemism that are similar to those observed in the Canarian flora for morphological data. Haplotype richness was higher in the Azores than in the Canaries and extensive dispersal mediated allopatry is apparent at the molecular level. The Azores were colonized at least twice independently by E. scoparia, whereas the Canarian haplotypes are monophyletic, suggesting that the greater distance between the Azores and the continent does not necessarily hamper the chances of successful colonization. [less ▲]

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See detailTelomere deregulations possess cytogenetic, phenotype, and prognostic specificities in acute leukemias.
CAPRARO, Valérie ULg; Zane, Linda; Poncet, Delphine et al

in Experimental Hematology (2011), 39(2), 195-2022

OBJECTIVE: Telomeres are protected by tightly regulated factors and elongated by telomerase. Short and/or deprotected chromosomes are recombinogenic and thereby cancer prone. MATERIALS AND METHODS ... [more ▼]

OBJECTIVE: Telomeres are protected by tightly regulated factors and elongated by telomerase. Short and/or deprotected chromosomes are recombinogenic and thereby cancer prone. MATERIALS AND METHODS: Together with the quantification of telomerase activity (TA), measuring telomere length (TL) and expression of the genes that govern telomere protection and elongation are useful for assessing telomere homeostasis. RESULTS: By these means we demonstrate that TL, hTERT, and TA are in the order acute myelogenous leukemia (AML) > T-cell acute lymphoblastic leukemia (T-ALL) > B-cell acute lymphoblastic leukemia (B-ALL) > T-ALL > AML, and B-ALL > AML > T-ALL. AML0 and AML3 display the lowest amounts of hTERT transcripts, and ALL and AML cells with cytogenetic abnormalities possess the shortest telomeres. hTERT expression includes phenotype-specific RNA maturation and correlates with TA but not with TL. A wide ratio of TA to hTERT expression between leukemia subtypes suggests phenotype-specific hTERT post-transcriptional deregulations. B- and T-ALL overexpress Ku70 and Pinx1, T-ALL PTOP and RAP1, and B-ALL TRF2, the expression of which is significantly higher in cases with abnormal karyotype. hTERT transcription and TL correlate with response to intensive chemotherapy, and hTERT and RAD50 are independent prognostic factors for survival. CONCLUSIONS: Each leukemia subtype possesses specific telomere dysregulations that rely on phenotype, karyotype, response to treatment, and survival. [less ▲]

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See detailSource parameters of the 2008 Bukavu-Cyangugu earthquake estimated from InSAR and teleseismic data
d'Oreye, Nicolas; Gonzalez, P.; Shuler, A. et al

in Geophysical Journal International (2011)

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See detailRapid effects of aggressive interactions on aromatase activity and oestradiol in discrete brain regions of wild male white-crowned sparrows
Charlier, Thierry ULg; Newman, Amy EM; Heimovics, Sarah A et al

in Journal of Neuroendocrinology (2011), 23

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See detailDevelopment and validation of a ultra-high-performance liquid chromatography-UV method for the detection and quantification of erectile dysfunction drugs and some of their analogues found in counterfeit medicines
Sacré, Pierre-Yves ULg; Deconinck, Eric; Chiap, Patrice ULg et al

in Journal of Chromatography. A (2011), 1218

Pharmaceutical counterfeiting is a permanently growing problem. Control laboratories are constantly analysing counterfeit medicines. In industrialised countries, one of the main counterfeited class of ... [more ▼]

Pharmaceutical counterfeiting is a permanently growing problem. Control laboratories are constantly analysing counterfeit medicines. In industrialised countries, one of the main counterfeited class of medicines are erectile dysfunction drugs. This paper describes the development and validation of a fast method to detect and quantify the three authorised phosphodiesterase type 5 inhibitors and five analogues. The method is based on the use of a sub-2 microns polar-embedded column with a gradient using acetonitrile as organic modifier and 10 mM ammonium formate buffer (pH 3.5) as aqueous component of the mobile phase. The separation was achieved in less than 4.5 min. The method has also been compared to the registered HPLC method for the assay of Viagra® which was considered as the reference method. The method is also compatible with on-line coupling mass spectrometry and will significantly reduce analysis times and solvent consumption. [less ▲]

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See detailQuand le préventif cède le pas au curatif : l'expérience d'une contamination fongique
Oger, Cécile ULg; Humblet, Anne-Cécile ULg

in 8eme congrès de l'Association des Cercles Francophones d'Histoire et d'Archéologie de Belgique. Congrès de Namur. Actes t. 5 (2011)

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See detailAssessment of Crohn’s disease activity by FDG-PET/CT through a novel quantitative approach.
SABOURY, B.; HUSTINX, Roland ULg; BROTHERS, B. et al

in Journal of Nuclear Medicine (The) (2011), 52(SUPPL), 284

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See detailAngry faces hold the eyes
Belopolsky, Artem; Devue, Christel ULg; Theeuwes, Jan

in Visual Cognition (2011), 19

Efficient processing of complex social and biological stimuli associated with threat is crucial for survival. Previous studies have suggested that threatening stimuli such as angry faces not only capture ... [more ▼]

Efficient processing of complex social and biological stimuli associated with threat is crucial for survival. Previous studies have suggested that threatening stimuli such as angry faces not only capture visual attention, but also delay the disengagement of attention from their location. However, in the previous studies disengagement of attention was measured indirectly and was inferred on the basis of delayed manual responses. The present study employed a novel paradigm that allows to directly examine the delayed disengagement hypothesis by measuring the time it takes to disengage the eyes from threatening stimuli. The results showed that participants were indeed slower to make an eye movement away from an angry face presented at fixation than from either a neutral or a happy face. This finding provides converging support that the delay in disengagement of attention is an important component of processing threatening information. [less ▲]

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See detailFibulin-3 fragments (FIB3-1 and FIB3-2) are potential new biomarkers for the diagnosis of osteoarthritis
Gharbi, M; Dubuc, JE; Deberg, Michelle ULg et al

in Annals of the Rheumatic Diseases (2011), 70(Suppl 3), 354

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See detailDensity of states of chaotic Andreev billiards
Kuipers, Jack; Engl, Thomas; Berkolaiko, Gregory et al

in PHYSICAL REVIEW B (2011), 83(19), 195316-21

Quantum cavities or dots have markedly different properties depending on whether their classical counterparts are chaotic or not. Connecting a superconductor to such a cavity leads to notable proximity ... [more ▼]

Quantum cavities or dots have markedly different properties depending on whether their classical counterparts are chaotic or not. Connecting a superconductor to such a cavity leads to notable proximity effects, particularly the appearance, predicted by random matrix theory, of a hard gap in the excitation spectrum of quantum chaotic systems. Andreev billiards are interesting examples of such structures built with superconductors connected to a ballistic normal metal billiard since each time an electron hits the superconducting part it is retroreflected as a hole (and vice versa). Using a semiclassical framework for systems with chaotic dynamics, we show how this reflection, along with the interference due to subtle correlations between the classical paths of electrons and holes inside the system, is ultimately responsible for the gap formation. The treatment can be extended to include the effects of a symmetry-breaking magnetic field in the normal part of the billiard or an Andreev billiard connected to two phase-shifted superconductors. Therefore, we are able to see how these effects can remold and eventually suppress the gap. Furthermore, the semiclassical framework is able to cover the effect of a finite Ehrenfest time, which also causes the gap to shrink. However, for intermediate values this leads to the appearance of a second hard gap-a clear signature of the Ehrenfest time. [less ▲]

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See detailEnd of life care in the operating room for non-heart-beating donors: organization at the University Hospital of Liege.
JORIS, Jean ULg; KABA, Abdourahmane ULg; LAUWICK, Séverine ULg et al

in Transplantation Proceedings (2011), 43(9), 3441-4

Non-heart-beating (NHB) organ donation has become an alternative source to increase organ supply for transplantation. A NHB donation program was implemented in our institution in 2002. As in many ... [more ▼]

Non-heart-beating (NHB) organ donation has become an alternative source to increase organ supply for transplantation. A NHB donation program was implemented in our institution in 2002. As in many institutions the end of life care of the NHB donor (NHBD) is terminated in the operating room (OR) to reduce warm ischemia time. Herein we have described the organization of end of life care for these patients in our institution, including the problems addressed, the solution proposed, and the remaining issues. Emphasis is given to our protocol elaborated with the different contributors of the chain of the NHB donation program. This protocol specifies the information mandatory in the medical records, the end of life care procedure, the determination of death, and the issue of organ preservation measures before NHBD death. The persisting malaise associated with NHB donation reported by OR nurses is finally documented using an anonymous questionnaire. [less ▲]

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