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See detailQuantifying hyporheic exchange at high spatial resolution using natural temperature variations along a first order stream
Westhoff, Martijn ULg; Gooseff, M. N.; Bogaard, T. A. et al

in Water Resources Research (2011), 47

Hyporheic exchange is an important process that underpins stream ecosystem function, and there have been numerous ways to characterize and quantify exchange flow rates and hyporheic zone size. The most ... [more ▼]

Hyporheic exchange is an important process that underpins stream ecosystem function, and there have been numerous ways to characterize and quantify exchange flow rates and hyporheic zone size. The most common approach, using conservative stream tracer experiments and 1-D solute transport modeling, results in oversimplified representations of the system. Here we present a new approach to quantify hyporheic exchange and the size of the hyporheic zone (HZ) using high-resolution temperature measurements and a coupled 1-D transient storage and energy balance model to simulate in-stream water temperatures. Distributed temperature sensing was used to observe in-stream water temperatures with a spatial and temporal resolution of 2 and 3 min, respectively. The hyporheic exchange coefficient (which describes the rate of exchange) and the volume of the HZ were determined to range between 0 and 2.7 × 10−3 s−1 and 0 and 0.032 m3 m−1, respectively, at a spatial resolution of 1–10 m, by simulating a time series of in-stream water temperatures along a 565 m long stretch of a small first-order stream in central Luxembourg. As opposed to conventional stream tracer tests, two advantages of this approach are that exchange parameters can be determined for any stream segment over which data have been collected and that the depth of the HZ can be estimated as well. Although the presented method was tested on a small stream, it has potential for any stream where rapid (in regard to time) temperature change of a few degrees can be obtained. [less ▲]

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See detailMultiparametric observation and analysis of the Sea
Alvera Azcarate, Aïda ULg; Poulain, Pierre-Marie

in Ocean Dynamics (2011)

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See detailNonlinear Normal Modes of a Full-Scale Aircraft
Peeters, Maxime ULg; Kerschen, Gaëtan ULg; Golinval, Jean-Claude ULg et al

in 29th International Modal Analysis Conference, Jacksonville, 2011 (2011)

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See detailHigh incidence of high-risk HPV in benign and malignant lesions of the larynx.
Duray, Anaelle; Descamps, Geraldine; Arafa, Mohammad et al

in International Journal of Oncology (2011), 39(1), 51-9

The aim of this study was to determine the prevalence of human papillomavirus (HPV) in patients with laryngeal benign lesions (LBLs) and laryngeal squamous cell carcinomas (LSCCs) using a sensitive E6/E7 ... [more ▼]

The aim of this study was to determine the prevalence of human papillomavirus (HPV) in patients with laryngeal benign lesions (LBLs) and laryngeal squamous cell carcinomas (LSCCs) using a sensitive E6/E7 type-specific PCR. Paraffin-embedded samples from LBL (n=39) and LSCC patients (n=67) were evaluated for the presence of HPV DNA by GP5+/GP6+ consensus PCR and E6/E7 type-specific PCR for HPV types 6, 11, 16, 18, 31, 33, 35, 39, 45, 51, 52, 53, 56, 58, 59, 66 and 68. In LSCCs, immunohistochemical staining of p16, p53 and EGFR was also assessed. The E6/E7 type-specific PCR showed that 44 out of 59 LSCC patients (i.e., 75%) had high-risk (hr) HPV types and that 27 out of 35 LBL patients (i.e., 77%) had hrHPV types. HPV-16 viral load was significantly higher in LSCC than in LBL patients (p<10-6). The presence of hrHPV DNA did not correlate with the proportion of disease-free patients. Comparable levels of p16, p53 and EGFR expression were observed in the hrHPV+ tumor group (100% p16+, 56% p53+ and 97% EGFR+) and in the HPV- or low-risk (lr) HPV+ tumor group (92% p16+, 66% p53+ and 100% EGFR+). A very high prevalence of oncogenic HPV-16 was found in a series of benign and malignant laryngeal lesions. LSCC appears to be characterized by an active hrHPV infection. In LSCCs, the hrHPV+ subgroup had a similar prognosis (in terms of risk of recurrence) as the HPV- subgroup. [less ▲]

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See detailAtlas linguistique de la Wallonie. Tome 17. Famille, vie et relations sociales
Baiwir, Esther ULg

Book published by PULg - Presses universitaires de Liège - Sciences Humaines (2011)

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See detailLes animaux ont-ils des droits subjectifs ? - Les droits des animaux
Delnoy, Michel ULg

in Revue de la Faculté de Droit de l'Université de Liège (2011), 2

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See detailCompte rendu de Alain SEGUY-DUCLOT, "Dialogue sur le Théétète"
Gavray, Marc-Antoine ULg

in Revue Philosophique de Louvain (2011), (1), 168-170

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See detailTransferts graisseux au niveau du sein: implications oncologiques.
NIZET, Jean-Luc ULg; Gonzalez, Arnaud ULg; Peulen, Olivier ULg et al

in Revue Médicale de Liège (2011), 66(5-6), 362-6

Autologous fat grafting for breast is increasing dramatically. This fat injection needs accurate technical conditions, and shows very good and long-lasting clinical results. Nevertheless, in breast ... [more ▼]

Autologous fat grafting for breast is increasing dramatically. This fat injection needs accurate technical conditions, and shows very good and long-lasting clinical results. Nevertheless, in breast conservative treatment sequellae, fat injection could lead to difficulties in breast imaging, but also there is some concerns about the potential oncologic risks of these procedures. [less ▲]

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See detailRecollection and familiarity processes in probable Alzheimer's disease: an fMRI study
Genon, Sarah ULg; Collette, Fabienne ULg; Salmon, Eric ULg et al

in Proceedings of the 5th International Conference on Memory (2011)

Cerebral activity associated with recollection and familiarity in 28 patients with Alzheimer’s disease (AD) and 17 healthy controls was directly measured in an event-related fMRI experiment during ... [more ▼]

Cerebral activity associated with recollection and familiarity in 28 patients with Alzheimer’s disease (AD) and 17 healthy controls was directly measured in an event-related fMRI experiment during performance of a recognition memory task with the process dissociation procedure. Brain regions associated to recollection were evidenced by contrasting activations for inclusion and exclusion conditions whereas brain regions related to familiarity were explored with the mean effect of the two conditions (at P < .05 corrected). Twelve patients had null recollection estimates (AD-), whereas 16 patients did experience some recollection although significantly less than controls (AD+). In AD+ and controls, recollection activated the posterior cingulate cortex (PCC). In contrast, familiarity estimates were equivalent in the 3 groups and were associated with brain activations around the intraparietal sulcus (IPS). Thus, in AD, impaired recollection is related to damage of the PCC whereas preserved familiarity is supported by the IPS. [less ▲]

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See detail'Tu manges aujourd’hui, tu ne manges pas le lendemain, ça c’est la pauvreté'. L’incertitude alimentaire à Bamako
de Suremain, Charles-Edouard; Razy, Elodie ULg

in Arditi, P.; Janin, P.; Marie, A. (Eds.) "La lutte contre l'insécurité alimentaire au Mali. Réalités et faux semblants" (2011)

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See detailWaremme
Pirlet, Pierre-François ULg

in Histoire & Patrimoine des communes de Belgique, Province de Liège (2011)

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See detailMalignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3+CD8+CD4- T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues.
Dewals, Benjamin G ULg; Vanderplasschen, Alain ULg

in Veterinary research (2011), 42(1), 95

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross ... [more ▼]

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. WD-MCF can be reproduced experimentally in rabbits. In a previous report, we demonstrated that WD-MCF induced by AlHV-1 is associated with a severe proliferation of CD8+ T cells in the lymphoid tissues. Here, we further studied the mononuclear leukocytic populations in both the lymphoid (throughout the infection and at time of euthanasia) and non-lymphoid (at time of euthanasia) organs during WD-MCF induced experimentally in rabbits. To reach that goal, we performed multi-colour flow cytometry stainings. The results obtained demonstrate that the development of WD-MCF correlates in peripheral blood with a severe increase of CD8+ cell percentages; and that CD3+CD8+CD4- T cells were the predominant cell type in both lymphoid and non-lymphoid organs at time of euthanasia. Further characterization of the mononuclear leukocytes isolated from both lymphoid and non-lymphoid tissues revealed that the CD8+ T cells express high levels of the activation markers CD25 and CD44, produce high amount of gamma-interferon (IFN-gamma) and perforin, and showed a reduction of interleukin-2 (IL-2) gene expression. These data demonstrate that the development of WD-MCF is associated with the expansion and infiltration of activated and cytotoxic CD3+CD8+CD4- T cells secreting high amount of IFN-gamma but low IL-2. [less ▲]

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See detailOptimisation of a new two-plate screening method for the detection of antibiotic residues in meat
Dang, Pham Kim; Degand, Guy ULg; Douny, Caroline ULg et al

in International Journal of Food Science & Technology (2011), 46

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See detailCouverture de pertes de substance du tibia distal par lambeau pedicule perforant en helice : deux cas cliniques.
Bous, Aurélie ULg; Ronsmans, C.; NIZET, Jean-Luc ULg et al

in Annales de Chirurgie Plastique Esthetique (2011)

Distal lower leg soft tissue defect is frequently a challenge to repair, particularly on the tibial crest. The coverage of this kind of lesion has some limitations because of regional minimal blood supply ... [more ▼]

Distal lower leg soft tissue defect is frequently a challenge to repair, particularly on the tibial crest. The coverage of this kind of lesion has some limitations because of regional minimal blood supply and paucity of local soft-tissue flaps. The perforator pedicled propeller (PPP) method tries to find a new place in lower leg reconstruction in bringing similar tissues at the recipient site and avoiding long and difficult free flap transfer or muscular sacrifice. The authors report on the use of PPP method for a tibial crest exposure after trauma and for a soft tissue defect with osteomyelitis on the tibial crest. [less ▲]

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See detailProfil des vendeurs de viande de chasse et évaluation de la biomasse commercialisée dans les marchés municipaux de Brazzaville, Congo.
Mbete, Roger Albert; Banga-Mboko, Henri; Ngokaka, Christophe et al

in Tropical Conservation Science (2011), 4(2), 203-217

The consumption of wildlife meat is an important source of animal protein for rural and urban population in Congo. A survey on bushmeat trade was undertaken in 21 municipal markets during four weeks, in ... [more ▼]

The consumption of wildlife meat is an important source of animal protein for rural and urban population in Congo. A survey on bushmeat trade was undertaken in 21 municipal markets during four weeks, in Brazzaville. The objective of this study was to define the traders’ profile and to evaluate the quantities of games and meat merchandised on the municipal markets. The study methodology combined two approaches: a quantitative one using a questionnaire as principal tool for collecting data, and a qualitative one associating informal survey methods via individual or group interviews. The results showed that women were the most involved in this trade (52%). Markets trader’s monthly income was estimated at 210,428 (US$420) ± 49,128 (US$98,256) FCFA. On average, the bushmeat traders’ were 39 ± 10 years old and 69% of them attended the two levels of secondary education. During four weeks, 3,711 animal carcasses were recorded on the 21 surveyed markets, representing almost 35,790 kg of biomass. Overall, 35 animal species were identified, including 9 the hunting of which was prohibited. The mammals constituted 93.8% of total number of hunted animals, with three dominant orders as the artiodactyls (49.2%), the rodents (22.6%) and the primates (17.7%), of which the Cephalophus, the Potamochoerus, the Atherurus and the Cercopithecus were the most represented. It was also noticed that trapping, an activity which leads to great losses, becomes very important, followed by be helpful alternatives to meet Congolese demand for bushmeat. For a sustainable management of the Congo’s faunic resources, this study suggests the introduction gun-hunting. The Congo-Ocean Railway and the National Road n°2 were used regularly in the transportation of game, to a 72% level. The district of Niari, Lekoumou, Sangha and Pool were the main sources of supply. At the present time, the meat quantities offered in Brazzaville markets don’t seem to be reduced because hunting areas extend always further, often to the detriment of protected areas. Despite the fact that such business squarely growths and shows evidence of overexploitation, activities promoting game farming and breeding of domestic species, in Brazzaville suburbs, are needed to mitigate the impact of bushmeat trade. [less ▲]

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See detailRés. CE 212.819, Smolcic - 212.989, Vanderlinden - 212.991, Fernandez-Grandjean
Delnoy, Michel ULg

in Aménagement - Environnement (2011), 4

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See detailBeyond matching on the mean in developmental disabilities research
Facon, Bruno; Magis, David ULg; Belmont, John M

in Research in Developmental Disabilities (2011), 32

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but ... [more ▼]

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but not the homogeneity of their variances or the shapes of their distributions. In the present paper, it is argued that group matching can go seriously wrong unless it directly confronts the distributional concerns by the use of well-known statistical indices and very simple graphical displays of the distributions. The question of the equivalency of item response profiles is also addressed since two participants or two groups of participants can obtain the same overall score on the matching variable by passing different items. In this case, the matching cannot be considered satisfactory because of poor concordance between the molar (overall score) and molecular (item scores) levels of matching. Angoff's Delta plot method, a statistical approach for detecting differential item functioning across small groups is described. It is promising as a simple way to prove whole test/individual item correspondence and, in addition, a useful tool for making post-hoc statistical analyses at the item level on the dependant variables. [less ▲]

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See detailLeibniz et la question du possible
Bouquiaux, Laurence ULg

in À l'émergence de la modernité : Histoire des idées au XVIIe siècle (2011)

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See detailSubject-specific cardiovascular system model-based identification and diagnosis of septic shock with a minimally invasive data set: animal experiments and proof of concept.
Chase, J Geoffrey; Lambermont, Bernard ULg; Starfinger, Christina et al

in Physiological Measurement (2011), 32(1), 65-82

A cardiovascular system (CVS) model and parameter identification method have previously been validated for identifying different cardiac and circulatory dysfunctions in simulation and using porcine models ... [more ▼]

A cardiovascular system (CVS) model and parameter identification method have previously been validated for identifying different cardiac and circulatory dysfunctions in simulation and using porcine models of pulmonary embolism, hypovolemia with PEEP titrations and induced endotoxic shock. However, these studies required both left and right heart catheters to collect the data required for subject-specific monitoring and diagnosis-a maximally invasive data set in a critical care setting although it does occur in practice. Hence, use of this model-based diagnostic would require significant additional invasive sensors for some subjects, which is unacceptable in some, if not all, cases. The main goal of this study is to prove the concept of using only measurements from one side of the heart (right) in a 'minimal' data set to identify an effective patient-specific model that can capture key clinical trends in endotoxic shock. This research extends existing methods to a reduced and minimal data set requiring only a single catheter and reducing the risk of infection and other complications-a very common, typical situation in critical care patients, particularly after cardiac surgery. The extended methods and assumptions that found it are developed and presented in a case study for the patient-specific parameter identification of pig-specific parameters in an animal model of induced endotoxic shock. This case study is used to define the impact of this minimal data set on the quality and accuracy of the model application for monitoring, detecting and diagnosing septic shock. Six anesthetized healthy pigs weighing 20-30 kg received a 0.5 mg kg(-1) endotoxin infusion over a period of 30 min from T0 to T30. For this research, only right heart measurements were obtained. Errors for the identified model are within 8% when the model is identified from data, re-simulated and then compared to the experimentally measured data, including measurements not used in the identification process for validation. Importantly, all identified parameter trends match physiologically and clinically and experimentally expected changes, indicating that no diagnostic power is lost. This work represents a further with human subjects validation for this model-based approach to cardiovascular diagnosis and therapy guidance in monitoring endotoxic disease states. The results and methods obtained can be readily extended from this case study to the other animal model results presented previously. Overall, these results provide further support for prospective, proof of concept clinical testing with humans. [less ▲]

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