References of "2011"
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See detailMalignant catarrhal fever induced by Alcelaphine herpesvirus 1 is characterized by an expansion of activated CD3+CD8+CD4- T cells expressing a cytotoxic phenotype in both lymphoid and non-lymphoid tissues.
Dewals, Benjamin G ULg; Vanderplasschen, Alain ULg

in Veterinary research (2011), 42(1), 95

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross ... [more ▼]

ABSTRACT: Alcelaphine herpesvirus 1 (AlHV-1) is carried by wildebeest asymptomatically. It causes a fatal lymphoproliferative disease named wildebeest-derived malignant catarrhal fever (WD-MCF) when cross-species transmitted to a variety of susceptible species of the Artiodactyla order. WD-MCF can be reproduced experimentally in rabbits. In a previous report, we demonstrated that WD-MCF induced by AlHV-1 is associated with a severe proliferation of CD8+ T cells in the lymphoid tissues. Here, we further studied the mononuclear leukocytic populations in both the lymphoid (throughout the infection and at time of euthanasia) and non-lymphoid (at time of euthanasia) organs during WD-MCF induced experimentally in rabbits. To reach that goal, we performed multi-colour flow cytometry stainings. The results obtained demonstrate that the development of WD-MCF correlates in peripheral blood with a severe increase of CD8+ cell percentages; and that CD3+CD8+CD4- T cells were the predominant cell type in both lymphoid and non-lymphoid organs at time of euthanasia. Further characterization of the mononuclear leukocytes isolated from both lymphoid and non-lymphoid tissues revealed that the CD8+ T cells express high levels of the activation markers CD25 and CD44, produce high amount of gamma-interferon (IFN-gamma) and perforin, and showed a reduction of interleukin-2 (IL-2) gene expression. These data demonstrate that the development of WD-MCF is associated with the expansion and infiltration of activated and cytotoxic CD3+CD8+CD4- T cells secreting high amount of IFN-gamma but low IL-2. [less ▲]

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See detailMolecular data challenge traditional subgeneric divisions in the leafy liverwort Radula
Devos, Nicolas; Renner, MAM; Gradstein, SR et al

in Taxon (2011), 60

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See detailBeyond matching on the mean in developmental disabilities research
Facon, Bruno; Magis, David ULg; Belmont, John M

in Research in Developmental Disabilities (2011), 32

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but ... [more ▼]

The matching of groups is a traditional way to control for confounding variables in developmental disability research. The equivalency of means across groups is routinely checked for these variables, but not the homogeneity of their variances or the shapes of their distributions. In the present paper, it is argued that group matching can go seriously wrong unless it directly confronts the distributional concerns by the use of well-known statistical indices and very simple graphical displays of the distributions. The question of the equivalency of item response profiles is also addressed since two participants or two groups of participants can obtain the same overall score on the matching variable by passing different items. In this case, the matching cannot be considered satisfactory because of poor concordance between the molar (overall score) and molecular (item scores) levels of matching. Angoff's Delta plot method, a statistical approach for detecting differential item functioning across small groups is described. It is promising as a simple way to prove whole test/individual item correspondence and, in addition, a useful tool for making post-hoc statistical analyses at the item level on the dependant variables. [less ▲]

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See detailCoûts et valeur ajoutée dans la commercialisation des perches de teck au Sud-Bénin
Aoudji, Augustin K. N.; Adégbidi, Anselme; Agbo, Valentin et al

in Cahiers Agricultures (2011), 20(6 (Novembre-Décembre 2011)), 480-486

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See detailRapid effects of aggressive interactions on aromatase activity and oestradiol in discrete brain regions of wild male white-crowned sparrows
Charlier, Thierry ULg; Newman, Amy EM; Heimovics, Sarah A et al

in Journal of Neuroendocrinology (2011), 23

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See detailCatalogo delle monete islamiche del Museo Bottacin
Bauden, Frédéric ULg

Book published by Comune di Padova, Musei e biblioteche (2011)

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See detailEditorial : Questionner le tourisme rural
Schmitz, Serge ULg; Decroly, Jean Michel

in Schmitz, Serge; Decroly, Jean Michel (Eds.) Questionner le tourisme rural (2011)

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See detailIdentification of a novel autoantigen in inflammatory bowel disease by protein microarray.
Vermeulen, Nathalie; de Beeck, Katrijn Op; Vermeire, Severine et al

in Inflammatory Bowel Diseases (2011), 17(6), 1291-300

BACKGROUND: Patients with inflammatory bowel disease (IBD) display immunoreactivity to self-antigens and microbial antigens. We used a protein microarray approach to identify novel autoantigens in IBD ... [more ▼]

BACKGROUND: Patients with inflammatory bowel disease (IBD) display immunoreactivity to self-antigens and microbial antigens. We used a protein microarray approach to identify novel autoantigens in IBD. METHODS: ProtoArray Human Protein Microarray v4.0 containing 8268 human proteins from Invitrogen (La Jolla, CA) was used. RESULTS: Twenty-five IBD patients and five healthy controls were screened for candidate autoantigens. For 256 antigens, IBD patients had a higher seroreactivity than controls. Twenty antigens were selected for further evaluation in a larger cohort (60 ulcerative colitis [UC] patients, 60 Crohn's disease [CD] patients, 60 healthy controls, and 60 gastrointestinal-diseased controls) by means of a customized protein microarray. Out of these 20 antigens, one antigen, family with sequence similarity 84 member A (FAM84A), was identified as a target antigen in IBD. Antibodies to FAM84A were significantly more prevalent in IBD patients (19%) than in gastrointestinal-diseased controls (1.7%) (P = 0.0008) and healthy controls (5%) (P = 0.01). Anti-FAM84A antibodies were found in 26.6% of UC patients and in 11.7% of CD patients. FAM84A was confirmed as target antigen in IBD by means of Western blotting in a large independent cohort (100 UC patients, 106 CD patients, 102 healthy controls, and 100 gastrointestinal-diseased controls). Antibodies to FAM84A were significantly more prevalent in IBD patients (20%) than in gastrointestinal-diseased controls (5%) (P = 0.0004) and healthy controls (0%) (P < 0.0001). Anti-FAM84A antibodies were found in 18% of UC patients and in 22% of CD patients. CONCLUSIONS: We identified FAM84A as a novel autoantigen in IBD. (Inflamm Bowel Dis 2011;). [less ▲]

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See detailThe Ri chicken breed and livelihoods in North Vietnam: characterisation and prospects
Moula, Nassim ULg; Do Duc, Luc ULg; Pham Kim, Dang et al

in Journal of Agriculture and Rural Development in the Tropics and Subtropics (2011), 112(1), 57-69

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See detailA non-invasive approach to study lifetime exposure and bioaccumulation of PCBs in protected marine mammals: PBPK modeling in harbor porpoises
Weijs, Liesbeth; Covaci, Adrian; Yang, Raymond S. H. et al

in Toxicology and Applied Pharmacology (2011), 256

In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically ... [more ▼]

In the last decade, physiologically based pharmacokinetic (PBPK) models have increasingly been developed to explain the kinetics of environmental pollutants in wildlife. For marine mammals specifically, these models provide a new, non-destructive tool that enables the integration of biomonitoring activities and in vitro studies. The goals of the present study were firstly to develop PBPK models for several environmental relevant PCB congeners in harbor porpoises (Phocoena phocoena), a species that is sensitive to pollution because of its limited metabolic capacity for pollutant transformation. These models were tested using tissue data of porpoises from the Black Sea. Secondly, the predictive power of the models was investigated for time trends in the PCB concentrations in North Sea harbor porpoises between 1990 and 2008. Thirdly, attempts were made to assess metabolic capacities of harbor porpoises for the investigated PCBs. In general, results show that parameter values from other species (rodents, humans) are not always suitable in marine mammal models, most probably due to differences in physiology and exposure. The PCB 149 levels decrease the fastest in male harbor porpoises from the North Sea in a time period of 18†years, whereas the PCB 101 levels decrease the slowest. According to the models, metabolic breakdown of PCB 118 is probably of lesser importance compared to other elimination pathways. For PCB 101 and 149 however, the presence of their metabolites can be attributed to bioaccumulation of metabolites from the prey and to metabolic breakdown of the parent compounds in the harbor porpoises. [less ▲]

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See detailThe Terms of Colours and their Changes in the Strasbourg Family Texts
Neven, Sylvie ULg; Möller, Robert ULg

in Bennewitz, I.; Schindler, A. (Eds.) Farbe im Mittelalter. Materialität-Medialität-Semantik (2011)

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See detailDuden - Deutsches Universalwörterbuch
Auberle, Anette; Eickhoff, Birgit; Haller-Wolf, Angelika et al

Book published by Dudenverlag - 7ème éd. (2011)

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See detailBilinguisme grec-latin et trinlinguisme grec-latin-copte en Égypte : Bibliographie générale
Carlig, Nathan ULg; Rochette, Bruno ULg

Textual, factual or bibliographical database (2011)

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See detailUnexpected entropy response to saline spraying at the end of posterior fossa surgery: a few cases report.
Clanet, Matthieu; BONHOMME, Vincent ULg; Lhoest, L. et al

in Acta anaesthesiologica Belgica (2011), 62(2), 87-90

The Spectral Entropy proposed to monitor the depth of anesthesia includes the State Entropy (SE) computed from the EEG (0.8-32 Hz frequency band), and the Response Entropy (RE) computed from EEG and ... [more ▼]

The Spectral Entropy proposed to monitor the depth of anesthesia includes the State Entropy (SE) computed from the EEG (0.8-32 Hz frequency band), and the Response Entropy (RE) computed from EEG and facial muscles activity (0.5-47 Hz frequency band). We report an unexpected Entropy response to saline spraying at the end of posterior fossa surgery. Six patients undergoing scheduled functional surgery of the posterior fossa were included in this report. They were anesthetized with propofol and remifentanil using TCI and received an intubation dose of rocuronium. At the end of surgery, saline spraying, performed for hemostatic purpose and wreckage elimination, resulted in a sustained increase in RE and SE without hemodynamic modification in four patients, while no change was observed in the two other ones. In one of the responding patients, 0.1 mg kg(-1) rocuronium attenuated the Entropy response. In the two non responders, repetition of spraying or rocuronium administration did not change Entropy value. Recovery from anesthesia was comparable in all patients and none of them complained from awareness. We conclude that Entropy can increase during posterior fossa surgery in non-paralyzed patients. This response probably reflects an increase in facial muscle activity rather than a change in depth of anesthesia, as far as it can be attenuated by a small dose of rocuronium. While this hypothesis requires further investigation, these observations suggest that saline spraying may confound interpretation of Entropy during posterior fossa surgery. [less ▲]

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See detailAn extended thermodynamic model of transient heat conduction at sub-continuum scales
Lebon, Georgy ULg; Machrafi, Hatim ULg; Grmela, M. et al

in Proceedings of the Royal Society A: Mathematical, Physical and Engineering Sciences (2011), 467

A thermodynamic description of transient heat conduction at small length and timescales is proposed. It is based on extended irreversible thermodynamics and the main feature of this formalism is to ... [more ▼]

A thermodynamic description of transient heat conduction at small length and timescales is proposed. It is based on extended irreversible thermodynamics and the main feature of this formalism is to elevate the heat flux vector to the status of independent variable at the same level as the classical variable, the temperature. The present model assumes the coexistence of two kinds of heat carriers: diffusive and ballistic phonons. The behaviour of the diffusive phonons is governed by a Cattaneo-type equation to take into account the high-frequency phenomena generally present at nanoscales. To include non-local effects that are dominant in nanostructures, it is assumed that the ballistic carriers are obeying a Guyer–Krumhansl relation. The model is applied to the problem of transient heat conduction through a thin nanofilm. The numerical results are compared with those provided by Fourier, Cattaneo and other recent models. [less ▲]

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See detailExiste-t-il des communautés sur Internet ? La réponse de trois études du mouvement du logiciel libre
Lejeune, Christophe ULg

in Actes des travaux du comité de recherche « Sociologie de la communication » (2011)

L'Open Directory Project, Debian et Wikipedia sont trois collectifs issus du mouvement du logiciel libre. Leur comparaison permet de dégager les traits communs et les différences d'organisation sociale de ... [more ▼]

L'Open Directory Project, Debian et Wikipedia sont trois collectifs issus du mouvement du logiciel libre. Leur comparaison permet de dégager les traits communs et les différences d'organisation sociale de ces trois collectifs médiatisés par la technologie.Nous examinons dans quelle mesure ces éléments empiriques s'accordent avec les définitions classiques de communauté (fut-elle virtuelle). Nous interrogeons dès lors l'opportunité de caractériser ces phénomènes au moyen d'une telle notion et identifiant deux alternatives : soit modifier les définitions classiques, soit proposer de nouvelles notions. Finalement, nous proposons la notion plus adéquate de collectifs médiatisés orientés vers un projet. [less ▲]

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