Les planètes géantes, leur composition et leur environnement magnétique

Scientific conference (2011)

Nous présentons un résumé de résultats récents et de programmes en développement relatifs à l'exploration du système solaire.

Quality assurance in repairing industrial floors: parameters and recommendations

in Zajc, A.; Sustercic, J. (Eds.) Moznot Pocenitive Izvajanja Betonarskih Del (2011)

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete ... [more ▼]

Since concrete has been used for more than a century, many structures need repair in different degrees and others need strengthening to withstand higher loads. Moreover, the number of new concrete structures is constantly increasing, and therefore repair or retrofitting requirements increase. Present concerns of sustainable development emphasizing repair or strengthening instead of new construction, acts as incentive to this trend. The bonded overlay technique is particularly suitable in the case of structures with large areas like industrial floors. This paper has the ambition to present reliable design methodology for the practitioner. Surface preparation, overlay design and material selection, application process and QC/QA are discussed and guidelines are proposed in order to enhance quality of repair operations. [less ▲]

Taking into account cell membrane permeability to account for the response of GFP microbial biosensors : integrating the secretome in the scaling-up procedures

in Récents Progrès en Génie des Procédés (2011), 101

Les bases de textes latins du LASLA : réalisations et projets

Scientific conference (2011)

Impact of the treatment conditions of a formic/acetic acid delignification method on chemical structure and antioxidant activity of beech wood lignin

Poster (2011)

The interest in lignocellulosic substrates is increasing because they are clearly identified for their high potential of development in energy and value-added molecules production. Indeed lignocellulosic ... [more ▼]

The interest in lignocellulosic substrates is increasing because they are clearly identified for their high potential of development in energy and value-added molecules production. Indeed lignocellulosic biomass constitutes a promising resource for a sustainable production of organic compounds and biobased products that could progressively replace molecules from the petrochemical industry. Until now lignocellulosic substrates were mainly used for the valorization of cellulose. Hemicelluloses and lignins were less valorized and often degraded after the process. However, due to their phenolic structure, lignins can be valorized in a lot of high-valued applications like vanillin production, replacement of petrochemical polymers, antioxidants for cosmetics and food industry, resins… In this study, a representative sample of beech wood (Fagus sylvatica L.) was collected in the region of Gaume in Belgium. Beech wood was delignified at atmospheric pressure by an organosolv process using a mixture of formic acid/acetic acid/water. The effect of cooking time and temperature was evaluated on the structure, physico-chemical properties and antioxidant activity of the lignins obtained from the black liquor after treatments. The structural and physico-chemical characteristics of the lignins were investigated with different tools like infrared spectrometry, thermogravimetric analysis, gel permeation chromatography after acetylation of lignins, NMR 1H, 13C and HSQC. The antioxidant activity was assessed by a spectrophotometric method using the α,α-diphenyl-β-picrylhydrazyl radical (DPPH). [less ▲]

Resequencing of positional candidates identifies low frequency IL23R coding variants protecting against inflammatory bowel disease.

in Nature Genetics (2011), 43(1), 43-7

Genome-wide association studies (GWAS) have identified dozens of risk loci for many complex disorders, including Crohn's disease. However, common disease-associated SNPs explain at most approximately 20 ... [more ▼]

Genome-wide association studies (GWAS) have identified dozens of risk loci for many complex disorders, including Crohn's disease. However, common disease-associated SNPs explain at most approximately 20% of the genetic variance for Crohn's disease. Several factors may account for this unexplained heritability, including rare risk variants not adequately tagged thus far in GWAS. That rare susceptibility variants indeed contribute to variation in multifactorial phenotypes has been demonstrated for colorectal cancer, plasma high-density lipoprotein cholesterol levels, blood pressure, type 1 diabetes, hypertriglyceridemia and, in the case of Crohn's disease, for NOD2 (refs. 14,15). Here we describe the use of high-throughput resequencing of DNA pools to search for rare coding variants influencing susceptibility to Crohn's disease in 63 GWAS-identified positional candidate genes. We identify low frequency coding variants conferring protection against inflammatory bowel disease in IL23R, but we conclude that rare coding variants in positional candidates do not make a large contribution to inherited predisposition to Crohn's disease. [less ▲]

Développer l'autonomie chez les adolescents: l'implémentation de l'outil EVa-GOA dans les services de l'Aide à la Jeunesse

in Observatoire : Revue d'Action Sociale & Médico-Sociale (2011), 68

Reproductive failure, possible maternal infanticide and cannibalism in wild moustached tamarins, Saguinus mystax

in Primates : Journal of Primatology (2011), 52

Lack of efficacy of low-dose spironolactone as adjunct treatment to conventional congestive heart failure treatment in dogs

in Journal of Veterinary Pharmacology & Therapeutics (2011)

Aldosterone plays an important role in the pathophysiology of heart failure. Aldosterone receptor blockade has been shown to reduce morbidity and mortality in human patients with advanced congestive left ... [more ▼]

Aldosterone plays an important role in the pathophysiology of heart failure. Aldosterone receptor blockade has been shown to reduce morbidity and mortality in human patients with advanced congestive left ventricular heart failure. This study was designed to assess the efficacy and tolerance of long-term low-dose spironolactone when added to conventional heart failure treatment in dogs with advanced heart failure. Eighteen client-owned dogs with advanced congestive heart failure due to either degenerative valve disease (n=11) or dilated cardiomyopathy (n=7) were included in this prospective, placebo-controlled, double-blinded, randomized clinical study. After initial stabilization including furosemide, angiotensin-converting enzyme inhibitors, pimobendan and digoxin, spironolactone at a median dose of 0.52 mg/kg (range 0.49-0.8 mg/kg) once daily (n=9) or placebo (n=9) was added to the treatment, and the dogs were reassessed 3 and 6 months later. Clinical scoring, echocardiography, electrocardiogram, systolic blood pressure measurement, thoracic radiography, sodium, potassium, urea, creatinine, alanine aminotransferase, aldosterone and aminoterminal atrial natriuretic propeptide were assessed at baseline, 3 and 6 months. Survival times were not significantly different between the two treatment groups. Spironolactone was well tolerated when combined with conventional heart failure treatment. [less ▲]

Quantification of rotenone in seeds of different species of yam bean (Pachyrhizus sp.) by a SPE HPLC-UV method

in Food Chemistry (2011), 131(4), 1531-1538

This study describes the development of a validated method for the quantification of rotenone in yam bean. The milled seeds were submitted to a Soxhlet dichloromethane extraction which allowed extracting ... [more ▼]

This study describes the development of a validated method for the quantification of rotenone in yam bean. The milled seeds were submitted to a Soxhlet dichloromethane extraction which allowed extracting 90% of the seeds rotenone. Elimination of the lipids was obtained via solid phase extraction. Rotenone was eluted with dichloromethane/methanol and the solution dried under vacuum and solubilised directly in methanol before injection in HPLC. The whole process was realised as much as possible protected from light and at temperatures lower than 40°C which allowed high recovery rates of spiked rotenone. Total error was used as criterion for the validation process and accuracy profiles drawn. The method allows the quantification of rotenone in yam bean seeds from 0.07% up to 1.25% (w/w). This method was applied to the quantification of rotenone in the seeds of several accessions of Pachyrhizus erosus and P. ahipa. The results range from 1.13 to 2.76 mg/g dry material. [less ▲]