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See detailEnhanced Activity of Meprin-a, a Pro-Migratory and Pro-Angiogenic Protease, in Colorectal Cancer
Lottaz, Daniel; Maurer, Christoph A; Noël, Agnès ULg et al

in PLoS ONE (2011), 6(11), 26450

Meprin-α is a metalloprotease overexpressed in cancer cells, leading to the accumulation of this protease in a subset of colorectal tumors. The impact of increased meprin-α levels on tumor progression is ... [more ▼]

Meprin-α is a metalloprotease overexpressed in cancer cells, leading to the accumulation of this protease in a subset of colorectal tumors. The impact of increased meprin-α levels on tumor progression is not known. We investigated the effect of this protease on cell migration and angiogenesis in vitro and studied the expression of meprin-α mRNA, protein and proteolytic activity in primary tumors at progressive stages and in liver metastases of patients with colorectal cancer, as well as inhibitory activity towards meprin-α in sera of cancer patient as compared to healthy controls. We found that the hepatocyte growth factor (HGF)- induced migratory response of meprin-transfected epithelial cells was increased compared to wild-type cells in the presence of plasminogen, and that the angiogenic response in organ-cultured rat aortic explants was enhanced in the presence of exogenous human meprin-α. In patients, meprin-α mRNA was expressed in colonic adenomas, primary tumors UICC (International Union Against Cancer) stage I, II, III and IV, as well as in liver metastases. In contrast, the corresponding protein accumulated only in primary tumors and liver metastases, but not in adenomas. However, liver metastases lacked meprin-α activity despite increased expression of the corresponding protein, which correlated with inefficient zymogen activation. Sera from cancer patients exhibited reduced meprin-α inhibition compared to healthy controls. In conclusion, meprin-α activity is regulated differently in primary tumors and metastases, leading to high proteolytic activity in primary tumors and low activity in liver metastases. By virtue of its pro-migratory and pro-angiogenic activity, meprin-α may promote tumor progression in colorectal cancer. [less ▲]

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See detailInfections à herpèsvirus chez les ruminants et les éléphants
Thiry, Etienne ULg; Thiry, J.

in Bulletin de l'Académie Vétérinaire de France (2011), 164

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See detailInterpretations of Polar Bear (Ursus maritimus) Tracks by Inuit Hunters: Inter-rater Reliability and Inferences Concerning Accuracy
Wong, Pamela; Van Coeverden de Groot, Peter; Fekken, Cynthia et al

in Canadian Field-Naturalist (2011), 125(2), 140-153

due to their tracking experience in pursuing Polar Bears (Ursus maritimus), Inuit hunters could provide non-invasive estimates of Polar Bear characteristics from tracks, and Polar Bear monitoring programs ... [more ▼]

due to their tracking experience in pursuing Polar Bears (Ursus maritimus), Inuit hunters could provide non-invasive estimates of Polar Bear characteristics from tracks, and Polar Bear monitoring programs could benefit from Inuit input. We determined i) inter-rater reliability of estimates of the sex, age, and size of Polar Bears, and estimates of the age of tracks made by a group of nine Inuit hunters who interpreted 78 tracks; ii) we made preliminary comparisons of sex and size estimates with conventional (scientific) estimates; iii) we catalogued the Polar Bear hunting experience and track interpretation techniques of nine Inuit hunters; and iv) we explored relationships between hunting experience and the ability to interpret tracks. The group of Inuit hunters made reliable and consistent estimates of Polar Bear sex, age, and size, as well as estimates of age of track (after data from one participant was excluded). Although our comparisons are based on small samples, our findings suggest that Inuit hunters may be accurate in estimating the sex of Polar Bears (74.42% agreement with genetic determinations) and the size of Polar Bears from their tracks. our data indicate shared tracking techniques used by hunters may explain high agreement in making specific estimates, while individual hunting experience and particular methods used to interpret tracks may lead to inter-rater reliability and accuracy in interpreting tracks. [less ▲]

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See detailFunctional analysis of hydrogen photoproduction in respiratory-deficient mutants of Chlamydomonas reinhardtii
Lecler, Renaud ULg; Godaux, Damien ULg; Vigeolas, Hélène ULg et al

in International Journal of Hydrogen Energy (2011), 36

In this paper, mitochondrial mutants of Chlamydomonas reinhardtii defective for respiratory complex I (NADH:ubiquinone oxidoreductase), complex III (ubiquinol cytochrome c oxidoreductase) and both ... [more ▼]

In this paper, mitochondrial mutants of Chlamydomonas reinhardtii defective for respiratory complex I (NADH:ubiquinone oxidoreductase), complex III (ubiquinol cytochrome c oxidoreductase) and both complexes I and III were analyzed for H2 photoproduction. Several parameters were followed during the S-deficiency stage and the anaerobic stage leading to H2 photoproduction. At the early aerobic S-deficiency stage, starch and neutral lipids accumulated in all strains but their amount was significantly decreased in mutants compared to wild type. During the H2 photoproduction process, whereas starch content strongly decreased in all strains, neutral lipid amount remained nearly unchanged, suggesting that starch degraded by glycolysis is the preferential substrate for energy production during anaerobiosis. The mutants displayed a decrease in H2 photoproduction correlating to the number of active mitochondrial proton-pumping sites lost in the strains. Our results thus highlight the critical role of oxidative phosphorylation during the first (aerobic) stage of S-starvation when carbon resources are accumulated. [less ▲]

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See detailCartographie des sols en Belgique : aperçu historique et présentation des travaux actuels de valorisation et de révision de la Carte Numérique des Sols de Wallonie
Legrain, Xavier ULg; Demarcin, Pierre ULg; Colinet, Gilles ULg et al

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2011), 15(S2), 647-656

Over the past few years, there has been growing concern about soils and their properties, thanks to greater environmental awareness. Consequently, existing documents on soil are valuable in risk ... [more ▼]

Over the past few years, there has been growing concern about soils and their properties, thanks to greater environmental awareness. Consequently, existing documents on soil are valuable in risk assessment and for the research of well-adapted solutions. In this context, this paper reviews the main stages of soil mapping in Belgium and presents current works to valorize the Digital Soil Map of Wallonia and update associated databases. Belgium is among the first countries to be completely covered by a detailed soil map (1:20,000). The origin of the Soil Map of Belgium, its realisation between 1947 and 1991, the principles and characteristics as well as the related products are described. But since its publication, due to the increasing need of soil information and thanks to the development of geographical information systems the Walloon part of the map was digitalised between 2000 and 2003 by the Digital Soil Map of Wallonia (DSMW) Project. From this early action at regional level, a selection of immediately derived products is presented and briefly commented. However, if these products go beyond the initial objective of agricultural production increase, they do not always meet the environmental challenges nor the future legislation at European, national and regional levels. To fill this gap, the recent tasks carried out by the DMSW team are presented through a description of their methodological and technical framework. The long-term objective is to build Regional Soil Information Systems based on the use of the Digital Soil Map of Wallonia as a tool of integration, structuring and referencing of pedological information. [less ▲]

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See detailComparaison empirique des méthodes classiques de détection du fonctionnement différentiel d’items en psychométrie
Magis, David ULg; De Boeck, Paul; Raîche, Gilles

in Raîche, Gilles; Paquette-Côté, Karine; Magis, David (Eds.) Des mécanismes pour assurer la validité de l’interprétation de la mesure en éducation. Tome 1 : la mesure. (2011)

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See detailTracking the construction of episodic future thoughts
D'Argembeau, Arnaud ULg; Mathy, Arnaud ULg

in Journal of Experimental Psychology. General (2011), 140

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See detailInvolvement of z-MMP-2 in Zebrafish lymphangiogenesis
Paupert, Jenny ULg; Pendeville, Hélène; Detry, Benoît ULg et al

Conference (2011)

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See detailpi N transition distribution amplitudes: Their symmetries and constraints from chiral dynamics
Pire, Bernard; Semenov-Tyan-Shanskiy, Kirill ULg; Szymanowski, Lech

in Physical Review. D : Particles and Fields (2011), 84

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See detailL'espace de jugement des compétences en arts de la scène. Analyse d'un dispositif d'insertion sur le marché du travail des comédiens
Brahy, Rachel ULg; Orianne, Jean-François ULg

in Revue Française de Socio-économie [=RFSE] (2011), 7

This article analyses a public instrument designed for the professional integration of young theatre performers in Belgium’s French Community: the “casting-training internship” (stage audition-formation ... [more ▼]

This article analyses a public instrument designed for the professional integration of young theatre performers in Belgium’s French Community: the “casting-training internship” (stage audition-formation). Drawing on the theoretical framework of the economy of conventions and on some empirical data from inquiries conducted in France, the authors study the innovative dimension of this instrument which allows for a variety of competences evaluation conventions. They also identify two major constraints affecting the conditions of a balanced skills assessment. [less ▲]

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See detailEl monje y la hija del verdugo
Bierce, Ambrose; Willson, Patricia ULg

Book published by Libros del Zorro Rojo (2011)

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See detailL'esthétique phénoménologique de Husserl : une approche contrastée
Steinmetz, Rudy ULg

Book published by Kimé (2011)

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See detailKurt Smith, Matter Matters. Metaphysics and Methodology in the Early Modern Period
Dubouclez, Olivier ULg

in Bulletin cartésien (2011)

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See detailGobernabilidad desde las agrupaciones usuarias del agua con fines agrícolas en 8 municipios del territorio de la Mancomunidad de Municipios de la cuenca del río Naranjo (MANCUERNA)
Estrada Orozco, Nick Kenner ULg; Mux, Victor

in Tikalia (2011), XXIX(1-2), 37-46

En Guatemala, para alcanzar los Objetivos de desarrollo del Milenio se implemen- tan Programas Conjuntos con el apoyo del Sistema de Naciones Unidas. Existen en la actualidad cinco Programas Conjuntos ... [more ▼]

En Guatemala, para alcanzar los Objetivos de desarrollo del Milenio se implemen- tan Programas Conjuntos con el apoyo del Sistema de Naciones Unidas. Existen en la actualidad cinco Programas Conjuntos apoyando temas de seguridad alimen- taria, construcción de la paz, cambio climático, género y gobernabilidad económi- ca del agua. En el marco del programa conjunto: “Gobernabilidad económica en agua y sanea- miento” se decidió realizar un estudio que permitiera conocer la gobernabilidad en el sector a partir de hacer un inventario de las agrupaciones usuarias de agua con fines agrícolas y conocer algunas de sus características, este estudio contó con la asesoría técnica de la Organización de las Naciones Unidas para la Agricultura y la Alimentación –FAO– y el apoyo en campo de las comunidades asociadas por el agua y el medio ambiente de la cuenca del río Naranjo –CADISNA– en coordina- ción con el Ministerio de Agricultura Ganadería y Alimentación –MAGA– y go- biernos locales. El estudio se realizó en 8 municipios, 3 del departamento de Quetzaltenango y 5 de San Marcos, se identificaron 126 grupos de riego, de ellos, 73 pudieron ser carac- terizados. Se conoció que el 92% de los 73 grupos tiene una junta directiva que vela por el funcionamiento del sistema y la producción se ve diversificada en al menos 14 diferentes hortalizas siendo la principal el cultivo de la Papa. Sin embar- go sólo el 45% paga una tarifa a su grupo y el 60% de los usuarios necesita crédito para poder producir, haciendo uso de al menos 271.99 Lts/seg de agua para fines agrícolas. [less ▲]

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See detailOnderneming en recht. Bedrijfsfiscaliteit
Peeters, Bart ULg

Book published by Knops Publishing (2011)

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See detailMultiparametric observation and analysis of the Sea
Alvera Azcarate, Aïda ULg; Poulain, Pierre-Marie

in Ocean Dynamics (2011)

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See detail"De la présomption et de la déclaration d'absence et de la déclaration judiciaire de décès"
Moreau, Pierre ULg

in Procédures particulières et droit judiciaire de la famille, 2ème édition, La jurisprudence du Code judiciaire commentée, P. Moreau (coord.), vol. III, G. de Leval (dir.) (2011)

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See detailAtlas linguistique de la Wallonie. Tome 17. Famille, vie et relations sociales
Baiwir, Esther ULg

Book published by PULg - Presses universitaires de Liège - Sciences Humaines (2011)

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See detailComparison between various methods for the evaluation of the fire resistance of concrete filled hollow steel columns
Fellah, Farid; Dotreppe, Jean-Claude ULg; Seridi, Ahcène et al

in Proceeding of the Romanian Academy. Series A, Mathematics, Physics, Technical Sciences, Information Science (2011), 12(4), 324-331

Hollow steel columns filled with bar-reinforced concrete are used extensively in the construction of high-rise buildings. Many research works devoted to the fire resistance of these profiles have been ... [more ▼]

Hollow steel columns filled with bar-reinforced concrete are used extensively in the construction of high-rise buildings. Many research works devoted to the fire resistance of these profiles have been performed in Europe and in North America. Though calculation methods are now proposed in codes, more practical tools are needed by the design engineers. It is not easy to develop such methods due to the large scatter of experimental results. In this article three methods based on quite different procedures are examined. Comparisons have been made between the results obtained by the three methods and test results. The potentialities of each method are examined, but also the domains in which they should be used with care, or even they should not be used. [less ▲]

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See detailStudying RNA-Protein Interactions In Vivo By RNA Immunoprecipitation
Selth, L. A.; Close, Pierre ULg; Svejstrup, J. Q.

in Methods in Molecular Biology (Clifton, N.J.) (2011), 791

The crucial roles played by RNA-binding proteins in all aspects of RNA metabolism, particularly in the regulation of transcription, have become increasingly evident. Moreover, other factors that do not ... [more ▼]

The crucial roles played by RNA-binding proteins in all aspects of RNA metabolism, particularly in the regulation of transcription, have become increasingly evident. Moreover, other factors that do not directly interact with RNA molecules can nevertheless function proximally to RNA polymerases and have significant effects on gene expression. RNA immunoprecipitation (RIP) is a powerful technique used to detect direct and indirect interactions between individual proteins and specific RNA molecules in vivo. Here, we describe RIP methods for both yeast and mammalian cells. [less ▲]

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