References of "2011"
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See detailHet geïntegreerde contrastieve onderzoeksdesign onder de loep
Hiligsmann, Philippe; Rasier, Laurent ULg

in Rasier, Laurent; Van Heuven, Vincent; Defrancq, Bart (Eds.) et al Nederlands in het perspectief van uitspraakverwerving en contrastieve taalkunde (2011)

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See detailFinal results of NKTR-102, a topoisomerase I inhibitor-polymer conjugate, in patients (Pts) with pretreated metastatic breast cancer (MBC) demonstrating significant antitumor activity
Garcia, A; Awada, A; Chan, S et al

in Journal of Clinical Oncology (2011), 29(supplement 27),

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See detailSubtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.
Rizzoli, R.; Akesson, K.; Bouxsein, M. et al

in Osteoporosis International (2011), 22

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this ... [more ▼]

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this association, but retrospective phase III trial analyses show no increased risk. Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is yet unproven. INTRODUCTION: A Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the International Osteoporosis Foundation has reviewed the evidence for a causal association between subtrochanteric fractures and long-term treatment with bisphosphonates, with the aim of identifying areas for further research and providing recommendations for physicians. METHODS: A PubMed search of literature from 1994 to May 2010 was performed using key search terms, and articles pertinent to subtrochanteric fractures following bisphosphonate use were analysed. RESULTS: Several clinical case reports and case reviews report a possible association between atypical fractures at the subtrochanteric region of the femur in bisphosphonate-treated patients. Common features of these 'atypical' fractures include prodromal pain, occurrence with minimal/no trauma, a thickened diaphyseal cortex and transverse fracture pattern. Some small case-control studies report the same association, but a large register-based study and retrospective analyses of phase III trials of bisphosphonates do not show an increased risk of subtrochanteric fractures with bisphosphonate use. The number of atypical subtrochanteric fractures in association with bisphosphonates is an estimated one per 1,000 per year. It is recommended that physicians remain vigilant in assessing their patients treated with bisphosphonates for the treatment or prevention of osteoporosis and advise patients of the potential risks. CONCLUSIONS: Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is unproven and requires further research. Were the case to be proven, the risk-benefit ratio still remains favourable for use of bisphosphonates to prevent fractures. [less ▲]

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See detailContinuous-flow production of alkyl nitrites
Monbaliu, Jean-Christophe ULg; Jorda, Jeremy; Chevalier, Bérengère et al

in Chimica Oggi = Chemistry Today (2011), 29

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See detailImpact of Greenland and Antarctic ice sheet interactions on climate sensitivity
Goelzer, H.; Huybrechts, P.; Loutre, M.-F. et al

in Climate Dynamics (2011), 37(5-6), 1005-1018

We use the Earth system model of intermediate complexity LOVECLIM to show the effect of coupling interactive ice sheets on the climate sensitivity of the model on a millennial time scale. We compare the ... [more ▼]

We use the Earth system model of intermediate complexity LOVECLIM to show the effect of coupling interactive ice sheets on the climate sensitivity of the model on a millennial time scale. We compare the response to a 2xCO2 warming scenario between fully coupled model versions including interactive Greenland and Antarctic ice sheet models and model versions with fixed ice sheets. For this purpose an ensemble of different parameter sets have been defined for LOVECLIM, covering a wide range of the model's sensitivity to greenhouse warming, while still simulating the present-day climate and the climate evolution over the last millennium within observational uncertainties. Additional freshwater fluxes from the melting ice sheets have a mitigating effect on the model's temperature response, leading to generally lower climate sensitivities of the fully coupled model versions. The mitigation is effectuated by changes in heat exchange within the ocean and at the sea-air interface, driven by freshening of the surface ocean and amplified by sea-ice-related feedbacks. The strength of the effect depends on the response of the ice sheets to the warming and on the model's climate sensitivity itself. With the ensemble approach in this study we cover a wide range of possible model responses. [less ▲]

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See detailBenthic remineralization in the northwest European continental margin (northern Bay of Biscay)
Suykens, Kim; Schmidt, Sabine; Delille, Bruno ULg et al

in Continental Shelf Research (2011), 31

We report a dataset of sediment characteristics and biogeochemical fluxes at the watersediment interface at the northwest European continental margin (northern Bay of Biscay). Cores were obtained in June ... [more ▼]

We report a dataset of sediment characteristics and biogeochemical fluxes at the watersediment interface at the northwest European continental margin (northern Bay of Biscay). Cores were obtained in June 2006, May 2007 and 2008, at 18 stations on the shelf break (120 to 180 m), and at 2 stations on the continental slope (520 m and 680 m). Water-sediment fluxes of dissolved oxygen (O2), total alkalinity (TA), nitrate (NO3-), and dissolved silicate (DSi) were measured at a total of 20 stations. Sediment characteristics include: grain size, chlorophyll-a (Chl-a) and phaeopigment (Phaeo) content, particulate organic (POC) and inorganic (PIC) carbon content, and lead-210 (210Pb) and thorium-234 (234Th) activities. Sediments were sandy (fine to coarse) with organic matter (OM) (1.0 - 4.0 %) and Chl-a (0.01 - 0.95 μg g-1) contents comparable to previous investigations in the same region, and a relatively high PIC fraction (0.8 - 10.2 %). Water-sediment O2 fluxes (-2.4 to -8.4 mmol O2 m-2 d-1) were low compared to other coastal environments and correlated well with OM and Chl-a content. 234Th activity profiles indicated that Chl-a sediment content was mainly controlled by physical mixing processes related to local hydrodynamics. The correlation between water-sediment fluxes of O2 and NO3- indicated a close coupling of nitrification/denitrification and total benthic organic carbon degradation. Dissolution of biogenic silica (0.05 to 0.95 mmol m-2 d-1) seemed uncoupled from organic carbon degradation, as characterized by water-sediment O2 fluxes. The link between water-sediment fluxes of TA and O2 indicated the occurrence of metabolic driven dissolution of calcium carbonates (CaCO3) in the sediments (~ 0.33 ± 0.47 mmol m-2 d-1) which represented ~ 1 % of the pelagic calcification rates due to coccolithophores measured during the cruises. These CaCO3 dissolution rates were below those reported in sediments of continental slopes and of the deep ocean, probably due to the high over-saturation with respect to CaCO3 of the water column overlying the continental shelf sediments of the northern Bay of Biscay. Rates of total benthic organic carbon degradation were low compared to water column rates of primary production and aphotic community respiration obtained during the cruises. [less ▲]

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See detailIs there really an Azores diversity enigma? Insights from the phylogeography of the heather Erica scoparia s.l.
Desamore, Aurélie ULg

Poster (2011)

The Azorean flora, in contrast to that of other archipelagos, is characterized by a paucity of evolutionary radiations and the widespread distribution of most endemics. Several hypotheses, including ... [more ▼]

The Azorean flora, in contrast to that of other archipelagos, is characterized by a paucity of evolutionary radiations and the widespread distribution of most endemics. Several hypotheses, including isolation from the continent, recent age, ecological homogeneity, and limited paleoclimatic variations, have been proposed to account for this pattern. These hypotheses are tested here within the context of the molecular phylogeography of the heather Erica scoparia s.l., a Mediterraneo-Atlantic species complex distributed across Macaronesia, North Africa and southwestern Europe. The marked molecular radiation of this species in the Azores, including an array of single-island endemics, suggests that the apparent homogeneity of the Azorean flora might, in fact, conceal undetected patterns of endemism that are similar to those observed in the Canarian flora for morphological data. Haplotype richness was higher in the Azores than in the Canaries and extensive dispersal mediated allopatry is apparent at the molecular level. The Azores were colonized at least twice independently by E. scoparia, whereas the Canarian haplotypes are monophyletic, suggesting that the greater distance between the Azores and the continent does not necessarily hamper the chances of successful colonization. [less ▲]

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See detailEffect of the activating agent on physico-chemical and electrical properties of activated carbon cloths developed from a novel cellulosic precursor
Ramos, ME; Bonelli, PR; Blacher, Silvia ULg et al

in Colloids and Surfaces A : Physicochemical and Engineering Aspects (2011), 378(1-3), 87-93

Different chemical reagents (phosphoric acid, boric acid, ammonium citrate, sodium dihydrogen phosphate, potassium dihydrogen phosphate, disodium hydrogen phosphate and trisodium phosphate) were employed ... [more ▼]

Different chemical reagents (phosphoric acid, boric acid, ammonium citrate, sodium dihydrogen phosphate, potassium dihydrogen phosphate, disodium hydrogen phosphate and trisodium phosphate) were employed to develop activated carbon cloths (ACC) by chemical activation of a lyocell precursor, in an attempt to explore their effect on main physico-chemical characteristics and electrical behaviour of the resulting ACC. The activating agent markedly influenced yield, elemental composition, and textural properties of the ACC. The ACC obtained with phosphoric and boric acids were essentially microporous, whereas those developed with the other reagents presented mesoporosity development. Phosphoric acid-derived samples showed the highest specific surface area (976 m2/g). The results also highlight the relevance of correcting the external surface adsorption in order to obtain reliable estimates of micropore volume. All the ACC were electrically conductive, their resistivity being also strongly dependent on the nature of the activating agent. The electrical resistivity of the ACC obtained with all the phosphorous compounds was successfully correlated with their C/H ratio and micropore volume [less ▲]

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See detailSocietal Vulnerability and Troublesome Youth Group Involvement TYG): the Mediating Role of Violent Values and Low Self-Control
Pauwels, Lieven; Vettenburg, Nicole; Gavray, Claire ULg et al

in International Criminal Justice Review (2011), 2(3), 283-296

both violent values and a low self-control mediate the effect of societal vulnerability on TYG

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See detailL’allo-immunisation fœto-maternelle ABO peut être sévère
SENTERRE, Thibault ULg; Mignon, J.-M.; Rigo, Jacques ULg

in Archives de Pédiatrie (2011), 18

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See detailRelationship between bone mineral density changes and risk of fractures among patients receiving calcium with or without vitamin D supplementation: a meta-regression
Rabenda, Véronique ULg; Bruyère, Olivier ULg; Reginster, Jean-Yves ULg

in Osteoporosis International (2011), 22

Surrogate measures of fracture risk, such as effects on bone mineral density, may be of great interest to assess the efficacy of available osteoporosis treatments. Our results suggest that bone mineral ... [more ▼]

Surrogate measures of fracture risk, such as effects on bone mineral density, may be of great interest to assess the efficacy of available osteoporosis treatments. Our results suggest that bone mineral density (BMD) changes cannot be used as a surrogate of anti-fracture efficacy, among patients receiving calcium, with or without vitamin D. Introduction: The purpose of this study is to examine the association between changes in bone mineral density with reduction in the risk of fractures in patients receiving calcium with or without vitamin D. Methods: We selected all randomized placebo-controlled clinical trials of calcium with or without vitamin D supplementation. To be included in this analysis, the studies were required to report both BMD (hip/proximal femur and/or lumbar spine) and the incidence of fractures. Metaregression analyses were used to examine the associations of changes in BMD with reduction in risk of fracture over the duration of each study. The change in BMD was the difference between changes (from baseline) observed in the active treatment group and placebo group. Results: A total of 15 randomized trials (n=47,365) were identified, most of whom (77%) came from the Women’s Health Initiative trial. Results show that larger increases in BMD at the lumbar spine were not associated with greater reduction in fracture risk. Concerning hip BMD changes, we found a statistically significant relationship between hip BMD changes and reduction in risk. However, results were not quite significant after excluding the both largest studies, in which BMD changes were measured in very small subset of patients. These points may have largely biased our results. Conclusions: In conclusion, there was no evidence of a relationship between BMD changes and reduction in risk of fractures among patients receiving calcium with or without vitamin D supplementation. Calcium and/or Vitamin D may reduce fracture rates through a mechanism independent of bone density. [less ▲]

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See detailARM XIX-la séquence SI.LA2 2 = si-la2-min (NP) et quelques relectures de noms propres
Colonna d'Istria, Laurent ULg

in Nouvelles Assyriologiques Brèves et Utilitaires (2011)

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See detailÉnergie nécessaire au broyage de la biomasse et des produits densifiés
Temmerman, Michaël ULg

in Biotechnologie, Agronomie, Société et Environnement = Biotechnology, Agronomy, Society and Environment [=BASE] (2011)

La littérature concernant la consommation énergétique du broyage dans les industries minières montre que cette problématique a été, et est encore, étudiée par de nombreux auteurs. Différents modèles de ... [more ▼]

La littérature concernant la consommation énergétique du broyage dans les industries minières montre que cette problématique a été, et est encore, étudiée par de nombreux auteurs. Différents modèles de broyage sont donc disponibles pour ces industries, en particulier pour le broyage des minerais. Les principaux modèles et certaines de leurs évolutions sont repris dans la présente revue. Le broyage de la biomasse quant à lui a été bien moins étudié. Quelques études ont néanmoins porté sur la mesure des consommations énergétiques engendrées par le broyage de biomasses particulières, dans des systèmes particuliers. Rares sont celles qui prennent en compte suffisamment de paramètres relatifs à la matière entrante et sortante (granulométrie, humidité, origine, etc.) ou les caractéristiques du système de broyage. Pratiquement, aucun modèle de broyage de la biomasse n’a donc été proposé. Concernant le broyage des produits densifiés, aucune donnée ne semble disponible. À la lueur des théories de broyage de l’industrie minière, cette étude propose donc les paramètres à prendre en compte pour une éventuelle modélisation du broyage de la biomasse et des produits densifiés. Mots-clés. Broyage, biomasse, pellets, briquettes, théories [less ▲]

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See detailK-type geomagnetic index nowcast with data quality control
Stankov, Stanimir; Stegen, Koen; Warnant, René ULg

in Annals of Geophysics = Annali di Geofisica (2011), 54(3), 285-295

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See detailX-ray CT study of the influence of liquid viscosity on fluid phase distribution in modular catalytic packings
Aferka, Saïd ULg; Viva, Aurora; Brunazzi, Elisabetta et al

in Chemical Engineering Transactions (2011), 24

In the frame of the present study, the influence of liquid viscosity on liquid holdup distribution in a packed column equipped with the modular catalytic packing Katapak-SP 11 is measured. Water and an ... [more ▼]

In the frame of the present study, the influence of liquid viscosity on liquid holdup distribution in a packed column equipped with the modular catalytic packing Katapak-SP 11 is measured. Water and an aqueous solution of glycerine, the viscosity of which equals 10 cP, are used as feed liquids. The estimation of liquid holdup is of great interest due to its strong influence on pressure drop, on solid wetting and on heat and mass transfer coefficients. The experimental technique used is high energy X-ray tomography, which is a unique technique to visualize the local liquid distribution inside the complex structure of packings and to quantify the liquid holdup at different scales. [less ▲]

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See detailUrinary NGAL measurement : Biological variation and ratio to creatinine
Delanaye, Pierre ULg; Rozet, Eric ULg; Krzesinski, Jean-Marie ULg et al

in Clinica Chimica Acta (2011), 412(3-4), 390

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See detailSelf-DNA release mediates the adjuvant effects of aluminum salts
Marichal, Thomas ULg; Ohata, K; Bedoret, Denis et al

Poster (2011)

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See detailA new Barremian (Early Cretaceous) ichthyosaur from western Russia
Fischer, Valentin ULg; Masure, Edwige; Arkhangelsky, Maxim et al

in Journal of Vertebrate Paleontology (2011), 31(5), 1010-1025

A new ophthalmosaurid ichthyosaur, Sveltonectes insolitus gen. et sp. nov., is described from a sub-complete and three-dimensionally preserved specimen from the late Barremian of western Russia. This new ... [more ▼]

A new ophthalmosaurid ichthyosaur, Sveltonectes insolitus gen. et sp. nov., is described from a sub-complete and three-dimensionally preserved specimen from the late Barremian of western Russia. This new taxon is supported by 11 cranial, dental, and postcranial autapomorphies, and is also characterized by features previously considered as autapomorphic for some other Ophthalmosauridae, such as a processus narialis on the prefrontal and relatively long hindfins with pre- and postaxial accessory digits. We conducted a new phylogenetic analysis of Thunnosauria, which supports a ‘Stenopterygius-origin’ for Ophthalmosauridae. Sveltonectes is regarded as the sister taxon of Aegirosaurus, which shares a similar skull roof construction. Contrary to most other Cretaceous ichthyosaurs, Sveltonectes is characterized by delicate and sharply pointed teeth, confirming that the Ophthalmosauridae were ecologically highly diversified during the Early Cretaceous [less ▲]

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