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See detailExperience-dependent induction of hypnagogic images during daytime naps: a combined behavioural and EEG study.
Kussé, Caroline ULg; Shaffii, Anahita ULg; Schrouff, Jessica ULg et al

in Journal of Sleep Research (2011)

This study characterizes hypnagogic hallucinations reported during a polygraphically recorded 90-min daytime nap following or preceding practice of the computer game Tetris. In the experimental group (N ... [more ▼]

This study characterizes hypnagogic hallucinations reported during a polygraphically recorded 90-min daytime nap following or preceding practice of the computer game Tetris. In the experimental group (N = 16), participants played Tetris in the morning for 2 h during three consecutive days, while in a first control group (N = 13, controlling the effect of experience) participants did not play any game, and in a second control group (N = 14, controlling the effect of anticipation) participants played Tetris after the nap. During afternoon naps, participants were repetitively awakened 15, 45, 75, 120 or 180 s after the onset of S1, and were asked to report their mental content. Reports content was scored by three judges (inter-rater reliability 85%). In the experimental group, 48 out of 485 (10%) sleep-onset reports were Tetris-related. They mostly consisted of images and sounds with very little emotional content. They exactly reproduced Tetris elements or mixed them with other mnemonic components. By contrast, in the first control group, only one report out of 107 was scored as Tetris-related (1%), and in the second control group only three reports out of 112 were scored as Tetris-related (3%; between-groups comparison; P = 0.006). Hypnagogic hallucinations were more consistently induced by experience than by anticipation (P = 0.039), and they were predominantly observed during the transition of wakefulness to sleep. The observed attributes of experience-related hypnagogic hallucinations are consistent with the particular organization of regional brain activity at sleep onset, characterized by high activity in sensory cortices and in the default-mode network. [less ▲]

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See detailUnexpected entropy response to saline spraying at the end of posterior fossa surgery: a few cases report.
Clanet, Matthieu; BONHOMME, Vincent ULg; Lhoest, L. et al

in Acta anaesthesiologica Belgica (2011), 62(2), 87-90

The Spectral Entropy proposed to monitor the depth of anesthesia includes the State Entropy (SE) computed from the EEG (0.8-32 Hz frequency band), and the Response Entropy (RE) computed from EEG and ... [more ▼]

The Spectral Entropy proposed to monitor the depth of anesthesia includes the State Entropy (SE) computed from the EEG (0.8-32 Hz frequency band), and the Response Entropy (RE) computed from EEG and facial muscles activity (0.5-47 Hz frequency band). We report an unexpected Entropy response to saline spraying at the end of posterior fossa surgery. Six patients undergoing scheduled functional surgery of the posterior fossa were included in this report. They were anesthetized with propofol and remifentanil using TCI and received an intubation dose of rocuronium. At the end of surgery, saline spraying, performed for hemostatic purpose and wreckage elimination, resulted in a sustained increase in RE and SE without hemodynamic modification in four patients, while no change was observed in the two other ones. In one of the responding patients, 0.1 mg kg(-1) rocuronium attenuated the Entropy response. In the two non responders, repetition of spraying or rocuronium administration did not change Entropy value. Recovery from anesthesia was comparable in all patients and none of them complained from awareness. We conclude that Entropy can increase during posterior fossa surgery in non-paralyzed patients. This response probably reflects an increase in facial muscle activity rather than a change in depth of anesthesia, as far as it can be attenuated by a small dose of rocuronium. While this hypothesis requires further investigation, these observations suggest that saline spraying may confound interpretation of Entropy during posterior fossa surgery. [less ▲]

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See detailEfficacy and safety of strontium ranelate in the treatment of knee ostoarthritis : a randomized, double-blind, placebo-controlled international trial
Reginster, Jean-Yves ULg; Chapurlat, R.; Christiansen, C. et al

in Osteoporosis International (2011), 22(S5), 742-743

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See detailorigines de la vie: où, quand, comment?
Javaux, Emmanuelle ULg

Speech (2011)

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See detailInfluence of bridge deck shape on extreme buffeting forces
Flamand, Olivier; Denoël, Vincent ULg

in Proceedigs of 13th International Conference on Wind Engineering (2011)

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See detailBackground/BiResonant decomposition of the non Gaussian buffeting response
Denoël, Vincent ULg

in Proceedigs of 13th International Conference on Wind Engineering (2011)

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See detailLipomatous hypertrophy of the interatrial septum: the typical echographic aspect is worth being known
ROYER, Ludovic ULg; HANS, Grégory ULg; CANIVET, Jean-Luc ULg et al

in Acta Anaesthesiologica Belgica (2011), 62(3), 157-159

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See detailLa Prise de Narbonne, laboratoire d'exploration de parentés textuelles
Henrard, Nadine ULg

in Bazin-Tachella, Sylvie; De Carné, Damien; Ott, Muriel (Eds.) Le souffle épique. L'Esprit de la chanson de geste (2011)

Analyse de l'épisode de la prise de Narbonne dans trois mises en prose du milieu du XVe siècle (Le Roman de Guillaume en prose, les Croniques et Conquestes de Charlemaine de David Aubert, et la Geste de ... [more ▼]

Analyse de l'épisode de la prise de Narbonne dans trois mises en prose du milieu du XVe siècle (Le Roman de Guillaume en prose, les Croniques et Conquestes de Charlemaine de David Aubert, et la Geste de Garin de Monglane du ms. 3351 de l'Arsenal), revenant sur la question très discutée des rapports génétiques qu'entretiennent ces trois textes. Les résultats d'un examen serré des concordances textuelles rejoignent les conclusions qu'avait émises Fr. Suard dans son étude sur le Roman de Guillaume en prose: la version de la prise de Narbonne du ms. de l'Arsenal et celle de David Aubert remonteraient à un modèle commun perdu, dérivé du Roman de Guillaume en prose conservé et très proche de ce dernier. [less ▲]

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See detailEffects of light on cognitive brain responses depend on circadian phase and sleep homeostasis.
Vandewalle, Gilles ULg; Archer, Simon N; Wuillaume, Catherine et al

in Journal of biological rhythms (2011), 26(3), 249-59

Light is a powerful modulator of cognition through its long-term effects on circadian rhythmicity and direct effects on brain function as identified by neuroimaging. How the direct impact of light on ... [more ▼]

Light is a powerful modulator of cognition through its long-term effects on circadian rhythmicity and direct effects on brain function as identified by neuroimaging. How the direct impact of light on brain function varies with wavelength of light, circadian phase, and sleep homeostasis, and how this differs between individuals, is a largely unexplored area. Using functional MRI, we compared the effects of 1 minute of low-intensity blue (473 nm) and green light (527 nm) exposures on brain responses to an auditory working memory task while varying circadian phase and status of the sleep homeostat. Data were collected in 27 subjects genotyped for the PER3 VNTR (12 PER3(5/5) and 15 PER3(4/4) ) in whom it was previously shown that the brain responses to this task, when conducted in darkness, depend on circadian phase, sleep homeostasis, and genotype. In the morning after sleep, blue light, relative to green light, increased brain responses primarily in the ventrolateral and dorsolateral prefrontal cortex and in the intraparietal sulcus, but only in PER3(4/4) individuals. By contrast, in the morning after sleep loss, blue light increased brain responses in a left thalamofrontoparietal circuit to a larger extent than green light, and only so in PER3(5/5) individuals. In the evening wake maintenance zone following a normal waking day, no differential effect of 1 minute of blue versus green light was observed in either genotype. Comparison of the current results with the findings observed in darkness indicates that light acts as an activating agent particularly under those circumstances in which and in those individuals in whom brain function is jeopardized by an adverse circadian phase and high homeostatic sleep pressure. [less ▲]

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See detailReduction in incidence of vertebral fractures with once yearly zoledronic acid in men with osteoporosis
Boonen, S.; Kaufman, J. M.; Reginster, Jean-Yves ULg et al

in Journal of Bone and Mineral Research (2011), 26(S1), 23

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See detailUsing test station and on-farm data for the genetic evaluation of Piétrain boars used on Landrace sows for growth performance
Dufrasne, Marie ULg; Rustin, Maité; Jaspart, Véronique et al

in Journal of Animal Science (2011), 89

The aim of this study was to develop a new genetic evaluation model to estimate the genetic merit of boars for growth based on 1) performance of their crossbred progeny fattened in the test station and 2 ... [more ▼]

The aim of this study was to develop a new genetic evaluation model to estimate the genetic merit of boars for growth based on 1) performance of their crossbred progeny fattened in the test station and 2) their own performance or those of relatives from the on-farm testing system. The model was a bivariate random regression animal model with linear splines and was applied to Piétrain boars from the Walloon Region of Belgium mated with Landrace sows. Data contained 1) 12,610 BW records from the test station collected on 1,435 crossbred pigs from Piétrain boars and Landrace sows, and 2) 52,993 BW records from the on-farm testing system collected on 50,670 pigs with a breed composition of at least 40% Piétrain or Landrace. Since 2007, 56 Piétrain boars have been tested in the station. Data used to estimate variance components and breeding values were standardized for the age to take into account heterogeneity of variances and then pre-adjusted at 210 d of age to put all records on the same scale. Body weight records from the test station and from the on-farm testing system were considered as 2 different traits. The heterosis effect was modeled as fixed regression on the heterozygosity coefficient. As all test station animals were similarly crossbred, smaller variation in heterozygosity caused the sampling error of the regression estimate at 210 d to be larger in the test station than in on-farm data with estimates of 28.35 ± 14.55 kg and 9.02 ± 0.67 kg, respectively. Therefore, the most likely reason for the large differences in estimates was sampling. Heritability estimates ranged from 0.37 to 0.60 at 210 and 75 d, respectively, for test station BW and from 0.42 to 0.60 at 210 d and 175 d, respectively, for on-farm BW. Genetic correlation decreased when the age interval between records increased, and were greater between ages for test station than for on-farm data. Genetic correlations between test station and on-farm BW at the same age were high: 0.90 at 175 d and 0.85 at 210 d. For the 56 boars tested in the station, the average reliability of their EBV for ADG between 100 and 210 d was improved from 0.60 using only test station data to 0.69 using jointly test station and on-farm data. Based on these results, the new model developed was considered as a good method of detection of differences in growth potential of Piétrain boars based on test station and on-farm data. [less ▲]

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See detailESSENTIAL OIL COMPOSITION AND ANTIMICROBIAL ACTIVITY OF ARTEMISIA HERBA-ALBA ASSO GROWN IN MOROCCO
Imelouane, B.; El Bachiri, A.; Ankit, M. et al

in Banat's Journal of Biotechnology (2011), I(2),

Volatile components of Artemisia herba-alba Asso essential oil obtained by hydrodistillation growing in eastern Morocco (Taforalt) were investigated by GC/FID and GC-MS. The major components were found to ... [more ▼]

Volatile components of Artemisia herba-alba Asso essential oil obtained by hydrodistillation growing in eastern Morocco (Taforalt) were investigated by GC/FID and GC-MS. The major components were found to be camphor (43.07%), camphene (7.2%), 1,8-cineole (7.08%), filifolone (7.04%), borneol (4.88%), and bornyl acetate (3,79%).The essential oil has been tested for antimicrobial activity against Gram-negative and Gram-positive bacteria. Inhibition of growth was tested by the agar diffusion method. The minimal Inhibitory Concentration (MIC) was determined by the method of microtitration assay. [less ▲]

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See detail5-ALA-PDT induces RIP3-dependent necrosis in glioblastoma
Coupienne, Isabelle ULg; Fettweis, Grégory ULg; Rubio-Romero, Noemi ULg et al

in Photochemical & Photobiological Sciences (2011)

Glioblastoma constitute the most frequent and deadliest brain tumors of astrocytic origin. They are resistant to all current therapies and are associated with a high rate of recurrence. Glioblastoma were ... [more ▼]

Glioblastoma constitute the most frequent and deadliest brain tumors of astrocytic origin. They are resistant to all current therapies and are associated with a high rate of recurrence. Glioblastoma were previously shown to respond to treatments by 5-aminolevulinic acid (5-ALA)-based photodynamic therapy (PDT) mainly by activating a necrotic type of cell death. The receptor-interacting protein 3 (RIP3) has recently been outlined as a key mediator of this caspase-independent form of programmed cell death. In the present study, we analyzed the necrotic mechanism induced by 5-ALA-PDT in human glioblastoma cells and explored the role of RIP3 in this context. Our results show that PDT-induced necrosis is dependent on RIP3, which forms aggregates and colocalizes with RIP1 following photosensitization. We demonstrate that PDT-mediated singlet oxygen production is the cause of RIP3-dependent necrotic pathway activation. We also prove that PDT induces the formation of a pro-necrotic complex containing RIP3 and RIP1 but lacking caspase-8 and FADD, two proteins usually part of the necrosome when TNF-α is used as a stimulus. Thus, we hypothesize that PDT might lead to the formation of a different necrosome whose components, besides RIP1 and RIP3, are still unknown. In most cases, glioblastoma are characterized by a constitutive activation of NF-κB. This factor is a key regulator of various processes, such as inflammation, immune response, cell growth or apoptosis. Its inhibition was shown to further sensitize glioblastoma cells to PDT-induced necrosis, however, no difference in RIP3 upshift or aggregation could be observed when NF-κB was inhibited. [less ▲]

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See detailPlectolyngbya hodgsonii: a novel filamentous cyanobacterium from Antarctic lakes
Taton, Arnaud; Wilmotte, Annick ULg; Smarda, Jan et al

in Polar Biology (2011), 34

A special cluster of filamentous, false-branched cyanobacteria, isolated from littoral mat samples in coastal lakes of the Larsemann Hills region (coll. by D. Hodgson) was studied by a polyphasic approach ... [more ▼]

A special cluster of filamentous, false-branched cyanobacteria, isolated from littoral mat samples in coastal lakes of the Larsemann Hills region (coll. by D. Hodgson) was studied by a polyphasic approach. This morphotype has several characters corresponding to the traditional genera Leptolyngbya (morphology of trichomes), Pseudophormidium (type of false branching) or Schizothrix (occasional multiple arrangement of trichomes in the sheaths). However, this cluster of strains is distinctly isolated according to its phylogenetic position (based on 16S rRNA gene sequences), and thus, a separate generic classification is justified. The cytomorphology of this generic entity is also characteristic. Therefore, a new genus (Plectolyngbya with the type species P. hodgsonii) was described. [less ▲]

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See detailLa progression et les ruptures d'apprentissage en histoire. Les programmes d'éveil et de formation historique dans l'enseignement maternel, primaire et secondaire en Communauté française de Belgique : continuités et discontinuités
Jadoulle, Jean-Louis ULg

in DUFAYS, Jean-Louis; DE KESEL, Myriam; MEURANT, Alain (Eds.) Le « curriculum » en questions. La progression et les ruptures des apprentissages disciplinaires de la maternelle à l’université (2011)

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See detailLes différentes manières de dire "jamais" en grec ancien
Denizot, Camille ULg

in Bulletin de la Société de Linguistique de Paris (2011), 106(1), 183-220

Le grec ancien dispose d’au moins quatre manières d’exprimer la négation adverbiale temporelle «ne...jamais»: οὐ...ποτέ, οὐ...πώποτε (en un seul mot ou en deux mots), οὐδέποτε et οὐδεπώποτε. En nous ... [more ▼]

Le grec ancien dispose d’au moins quatre manières d’exprimer la négation adverbiale temporelle «ne...jamais»: οὐ...ποτέ, οὐ...πώποτε (en un seul mot ou en deux mots), οὐδέποτε et οὐδεπώποτε. En nous appuyant sur un corpus de prose oratoire classique (Lysias et Démosthène), nous tentons de rendre compte de l’emploi d’une série en πώποτε (souvent traduite par «ne...jamais encore») à côté d’une série en ποτέ. Pour ce faire, nous mettons en évidence des différences de plusieurs sortes entre les deux séries. Il existe en effet des différences syntaxiques, puisque πώποτε est un terme à polarité négative, tout comme πώ qui entre dans sa formation, et des différences sémantiques, particulièrement aspectuelles et modales, liées au sens de πώ (habituellement traduit par «ne...pas encore»). Avec la série en πώποτε, sur le plan aspectuel, le procès négatif est susceptible de devenir positif au-delà d’un moment de référence défini dans le discours, et sur le plan modal, ce procès négatif s’oppose à un procès positif auquel on aurait pu s’attendre. La particularité du grec ancien provient des cas où l’indéfini πώ, terme à polarité négative, impose une lecture de πώποτε comme un indéfini de libre choix («jamais, à quelque moment que ce soit») et non comme un adverbe de phase («jamais encore»). [less ▲]

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