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See detailPresbyastasie et application de la réhabilitation vestibulaire en gériatrie
Costa de Araujo, Pedro ULiege; DEMANEZ, Laurent CH P ULiege; Lechien, Jerôme et al

in Revue Médicale de Liège (2011), 66(3), 130-4

Balance disorders can have a major functional impact among the elderly. The main risk is falling. Three elements are implicated in the loss of balance: vision, proprioception and the vestibular system ... [more ▼]

Balance disorders can have a major functional impact among the elderly. The main risk is falling. Three elements are implicated in the loss of balance: vision, proprioception and the vestibular system. This article will discuss mainly vestibular damage and its implications. The assessment of balance disorders, particularly in geriatric patients, is based on validated scales composed of several items. These provide scores and are based on the results of chronometric measurements. They can be useful for the application of Vestibular Rehabilitation (VR ), a technique improving the adaptation and autonomy of these patients. Vestibular rehabilitation is therefore part of an overall support, the goal of therapy being to improve daily life and to reduce the risk of falls. [less ▲]

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See detailTémoignage 2: les mathématiques dans le programme du cursus en sciences biologiques
Thiry, Marc ULiege

Diverse speeche and writing (2011)

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See detailManipulation of Droplets onto a Planar Interface
Gilet, Tristan ULiege; Terwagne, Denis ULiege; Vandewalle, Nicolas ULiege et al

in miller, reinhard; liggieri, libero (Eds.) Progress in Colloid and Interface Science, 2 (2011)

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See detailPopulation of nonnative States of lysozyme variants drives amyloid fibril formation.
Buell, Alexander K.; Dhulesia, Anne; Mossuto, Maria F. et al

in Journal of the American Chemical Society (2011), 133(20), 7737-43

The propensity of protein molecules to self-assemble into highly ordered, fibrillar aggregates lies at the heart of understanding many disorders ranging from Alzheimer's disease to systemic lysozyme ... [more ▼]

The propensity of protein molecules to self-assemble into highly ordered, fibrillar aggregates lies at the heart of understanding many disorders ranging from Alzheimer's disease to systemic lysozyme amyloidosis. In this paper we use highly accurate kinetic measurements of amyloid fibril growth in combination with spectroscopic tools to quantify the effect of modifications in solution conditions and in the amino acid sequence of human lysozyme on its propensity to form amyloid fibrils under acidic conditions. We elucidate and quantify the correlation between the rate of amyloid growth and the population of nonnative states, and we show that changes in amyloidogenicity are almost entirely due to alterations in the stability of the native state, while other regions of the global free-energy surface remain largely unmodified. These results provide insight into the complex dynamics of a macromolecule on a multidimensional energy landscape and point the way for a better understanding of amyloid diseases. [less ▲]

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See detailLearning a motor skill: Effects of blocked versus random practice. A review
Merbah, Sarah ULiege; Meulemans, Thierry ULiege

in Psychologica Belgica (2011), 51

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See detailComputation of induced fields into the human body by using dual formulations
Scorretti, Riccardo; V Sabariego, Ruth ULiege; Morel, L. et al

(2011)

In this work we present the use of two dual formulations to compute Extremely Low frequency (ELF) induced fields into the human body. This allows to estimate the numerical error, as well as rigorously ... [more ▼]

In this work we present the use of two dual formulations to compute Extremely Low frequency (ELF) induced fields into the human body. This allows to estimate the numerical error, as well as rigorously bound the (global) co-energy. This method is here applied to the classical case of the exposure to a homogeneous magnetic field. [less ▲]

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See detailSurgical resection of a sphenoid wing meningioma in a patient with Glanzmann thrombasthenia.
WERTZ, Damien ULiege; Boveroux, Pierre ULiege; PETERS, Pierre ULiege et al

in Acta anaesthesiologica Belgica (2011), 62(2), 83-6

Glanzmann thrombasthenia (GT) is a rare autosomal recessive disorder characterized by a deficiency or functional defect of platelet glycoprotein (GP) IIb/IIIa. Physiologically, this platelet receptor ... [more ▼]

Glanzmann thrombasthenia (GT) is a rare autosomal recessive disorder characterized by a deficiency or functional defect of platelet glycoprotein (GP) IIb/IIIa. Physiologically, this platelet receptor mediates aggregation of activated platelets by binding the adhesive proteins, fibrinogen, von Willebrand factor (VWF) and fibronectin. This facilitates attachment and aggregation of platelets at sites of vascular injury. We reported the management of a pterional meningioma resection in a patient with Glanzmann thrombasthenia, with recombinant factor VIIa (rFVIIa - NovoSeven) as haemostatic agent. A 48-year-old woman suffering from Glanzmann thrombasthenia was scheduled for spheno-orbital meningioma en plaque surgery. Because of repeated platelet transfusions, this patient developed isoantibodies against missing GPIIbIIIa and alloantibodies against Human Leukocyte Antigen (HLA) leading to refractoriness to platelet transfusions. We observed that Novoseven offered sufficient haemostasis conditions. Therefore, we noticed a deep vein thrombosis. This imposed us to use low weight molecular heparin despite recent surgery. [less ▲]

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See detailTranscranial magnetic stimulation-evoked EEG/cortical potentials in physiological and pathological aging.
Casarotto, Silvia; Maatta, Sara; Herukka, Sanna-Kaisa et al

in Neuroreport (2011), 22(12), 592-7

The frontal cortex undergoes macrostructural and microstructural changes across the lifespan. These changes can be entirely physiological, such as the ones occurring in elderly individuals who are ... [more ▼]

The frontal cortex undergoes macrostructural and microstructural changes across the lifespan. These changes can be entirely physiological, such as the ones occurring in elderly individuals who are cognitively intact, or pathological, such as the ones occurring in patients with Alzheimer's disease. Here, we use simultaneous electroencephalography (EEG) and transcranial magnetic stimulation (TMS) to study how the excitability of the frontal cortex changes during healthy and pathological aging. Hence, we compared the TMS-evoked EEG potentials collected in healthy elderly individuals with the ones collected in healthy young individuals, and in patients with Alzheimer's disease. We have shown that the EEG response to TMS of the left superior frontal cortex is not affected by physiological aging but is markedly altered by cognitive impairment. [less ▲]

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See detailOral salt supplementation and long-distance exercise
Lehance, Cédric ULiege; Rodriguez de la Cruz, Carlos ULiege; Counet, Laurence ULiege et al

in British Journal of Sports Medicine (2011), 45

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See detailMultimodal neuroimaging in patients with disorders of consciousness showing "functional hemispherectomy".
Bruno, Marie-Aurélie ULiege; Fernandez-Espejo, D.; Lehembre, Remy ULiege et al

in Progress in Brain Research (2011), 193

Beside behavioral assessment of patients with disorders of consciousness, neuroimaging modalities may offer objective paraclinical markers important for diagnosis and prognosis. They provide information ... [more ▼]

Beside behavioral assessment of patients with disorders of consciousness, neuroimaging modalities may offer objective paraclinical markers important for diagnosis and prognosis. They provide information on the structural location and extent of brain lesions (e.g., morphometric MRI and diffusion tensor imaging (DTI-MRI) assessing structural connectivity) but also their functional impact (e.g., metabolic FDG-PET, hemodynamic fMRI, and EEG measurements obtained in "resting state" conditions). We here illustrate the role of multimodal imaging in severe brain injury, presenting a patient in unresponsive wakefulness syndrome (UWS; i.e., vegetative state, VS) and in a "fluctuating" minimally conscious state (MCS). In both cases, resting state FDG-PET, fMRI, and EEG showed a functionally preserved right hemisphere, while DTI showed underlying differences in structural connectivity highlighting the complementarities of these neuroimaging methods in the study of disorders of consciousness. [less ▲]

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See detailToxicologie clinique et médico-légale
Renaux, André; Renaux - Muylkens, Isabelle; Charlier, Corinne ULiege et al

in Beauthier, Jean-Pol (Ed.) Traité de Médecine légale (2011)

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See detailPerméabilité au gaz et aux ions chlore des mortiers à base de laitier de faible hydraulicité
Hadj Sadok, Ahmed; Kenaï, Saïd; Courard, Luc ULiege

in Innovation et Valorisation dans le génie civil et les matériaux de construction (2011)

La durabilité des bétons au laitier de haut fourneau dépend fortement de l’activité hydraulique du laitier. Dans cette étude, un laitier algérien, caractérisé par une faible hydraulicité, est utilisé dans ... [more ▼]

La durabilité des bétons au laitier de haut fourneau dépend fortement de l’activité hydraulique du laitier. Dans cette étude, un laitier algérien, caractérisé par une faible hydraulicité, est utilisé dans la fabrication de mortiers comme substituant du ciment à des taux de 0, 30 et 50%. En plus d’une caractérisation mécanique, l’effet du laitier sur la durabilité des mortiers est évalué par des essais de perméabilité à l’oxygène, de diffusion de chlorures en régime permanent ainsi que de conduction des ions chlore (essai accéléré ASTM). Les résultats montrent, malgré une faible réactivité du laitier, une amélioration de la perméabilité à l’oxygène à long terme (360 jours) pour les mortiers au laitier, particulièrement pour un taux de 50%. La présence du laitier réduit la perméabilité aux ions chlore, d’une part, en augmentant le temps de passage des chlorures à travers le mortier et, d’autre part, en diminuant le taux de diffusion. Par ailleurs, une faible conduction des chlorures est observée pour les mortiers au laitier, montrant une similitude avec les résultats d’essai de diffusion en régime permanent. [less ▲]

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See detailCardiometabolic Syndrome
Alkerwi, A; Albert, Adelin ULiege; Guillaume, Michèle ULiege

in Gasparyan, AY (Ed.) Cardiovascular Risk Factors (2011)

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See detailType III frontal sinusotomy: surgical technique, indications, outcomes, a multi-university retrospective study of 120 cases.
Eloy, P.; Vlaminck, S.; Jorissen, M. et al

in B-ENT (2011), 7 Suppl 17

Draf in 1991. The procedure--which is also known as the modified endoscopic Lothrop procedure--aims to create the largest possible anteroposterior and lateral to lateral opening between both frontal ... [more ▼]

Draf in 1991. The procedure--which is also known as the modified endoscopic Lothrop procedure--aims to create the largest possible anteroposterior and lateral to lateral opening between both frontal sinuses and the nasal cavities. This requires the resection of the medial floor of both frontal sinuses, the intersinus septum and the superior nasal septum. The authors present a retrospective study including a cohort of 120 patients who underwent surgery in six Belgian university ENT departments. Mean follow-up was 24.6 months (range: 5-36 months). This paper describes the surgical procedure and reviews the indications, comorbidities, outcomes and complications of the type III frontal sinusotomy. Some correlations are also established with the data published in the worldwide literature. The authors conclude that the Draf III is a demanding procedure requiring considerable expertise in endoscopic sinus surgery. The procedure is effective with a success rate of 87.5%. Indeed, 12.5% of patients only experienced closure of the neoostium while 20% of all the patients had unchanged or worse symptomatology. The percentage of post-operative complications is 7.5%. All complications were managed successfully. [less ▲]

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