References of "2011"
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See detailDeterminants of high, median and low rates of caesarean deliveries in Belgium
Absil, Gaëtan ULg; Van Parys, A. S.; Bednarek, Stéphanie et al

Report (2011)

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See detailPresent day carbon dioxide fluxes in the coastal ocean and possible feedbacks under global change
Borges, Alberto ULg

in da Silva Duarte, P. M.; Santana Casiano, J. M. (Eds.) Oceans and the atmospheric carbon content (2011)

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See detailL'imperatrice. Le Molte Vite di Indira Gandhi
Maiorano, Diego ULg

in Storia della Storiografia (2011), 58

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See detailOptimal design of multi-subject blocked fMRI experiments.
Maus, Bärbel ULg; van Breukelen, Gerard J P; Goebel, Rainer et al

in NeuroImage (2011), 56(3), 1338-1352

The design of a multi-subject fMRI experiment needs specification of the number of subjects and scanning time per subject. For example, for a blocked design with conditions A or B, fixed block length and ... [more ▼]

The design of a multi-subject fMRI experiment needs specification of the number of subjects and scanning time per subject. For example, for a blocked design with conditions A or B, fixed block length and block order ABN, where N denotes a null block, the optimal number of cycles of ABN and the optimal number of subjects have to be determined. This paper presents a method to determine the optimal number of subjects and optimal number of cycles for a blocked design based on the A-optimality criterion and a linear cost function by which the number of cycles and the number of subjects are restricted. Estimation of individual stimulus effects and estimation of contrasts between stimulus effects are both considered. The mixed-effects model is applied and analytical results for the A-optimal number of subjects and A-optimal number of cycles are obtained under the assumption of uncorrelated errors. For correlated errors with a first-order autoregressive (AR1) error structure, numerical results are presented. Our results show how the optimal number of cycles and subjects depend on the within- to between-subject variance ratio. Our method is a new approach to determine the optimal scanning time and optimal number of subjects for a multi-subject fMRI experiment. In contrast to previous results based on power analyses, the optimal number of cycles and subjects can be described analytically and costs are considered. [less ▲]

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See detailNegations at Medinet Habu
Gillen, Todd Jonathan ULg

Conference (2011)

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See detailBrain natriuretic peptide in asymptomatic degenerative mitral regurgitation: determinants and impact on outcome.
Van de Heyning, C; Magne, Julien ULg; Mahjoub, H et al

Conference (2011)

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See detailA discrete competitive facility location model with variable attractiveness
Kucukaydin, Hande ULg; Aras, Necati; Altinel, I. Kuban

in Journal of the Operational Research Society (2011), 62(9), 1726-1741

We consider the discrete version of the competitive facility location problem in which new facilities have to be located by a new market entrant firm to compete against already existing facilities that ... [more ▼]

We consider the discrete version of the competitive facility location problem in which new facilities have to be located by a new market entrant firm to compete against already existing facilities that may belong to one or more competitors. The demand is assumed to be aggregated at certain points in the plane and the new facilities can be located at predetermined candidate sites. We employ Huff’s gravity-based rule in modelling the behaviour of the customers where the probability that customers at a demand point patronize a certain facility is proportional to the facility attractiveness and inversely proportional to the distance between the facility site and demand point. The objective of the firm is to determine the locations of the new facilities and their attractiveness levels so as to maximize the profit, which is calculated as the revenue from the customers less the fixed cost of opening the facilities and variable cost of setting their attractiveness levels. We formulate a mixed-integer nonlinear programming model for this problem and propose three methods for its solution: a Lagrangean heuristic, a branch-and-bound method with Lagrangean relaxation, and another branch-and-bound method with nonlinear programming relaxation. Computational results obtained on a set of randomly generated instances show that the last method outperforms the others in terms of accuracy and efficiency and can provide an optimal solution in a reasonable amount of time. [less ▲]

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See detailThe extension of the INCL model for simulation of shielding in space
Pedoux, Sophie ULg; Cugnon, Joseph ULg; Mancusi, Davide ULg et al

in Advances in Space Research (2011), 48(2), 383-389

Radiation hazard for space missions is mainly due to cosmic ray protons, helium nuclei and light ions, whose energy spectrum is maximum around 1 GeV per nucleon but remains non-negligible for energies up ... [more ▼]

Radiation hazard for space missions is mainly due to cosmic ray protons, helium nuclei and light ions, whose energy spectrum is maximum around 1 GeV per nucleon but remains non-negligible for energies up to 15 GeV per nucleon. Nuclear reactions induced by high energy protons are often described by intranuclear cascade plus evaporation models. The attention is focused here on the Liège Intranuclear Cascade model (INCL), which has been shown to reproduce fairly well a great deal of experimental data for nucleon-induced reactions in the 200 MeV to 2 GeV range, when coupled with the ABLA evaporation-fission code. In order to extend the model to other conditions relevant for space radiation, three improvements of INCL are under development. They are reported on here. First, the reaction model has been extended to nucleon-nucleus reactions at incident energies up to 15 GeV, mainly by the inclusion of additional pion production channels in nucleon-nucleon collisions during the cascade. Second, a coalescence mechanism for the emission of light charged particles has been implemented recently. Finally, the model has been modified in order to accommodate light ions as projectiles. First results are shown and compared with illustrative experimental data. Implications for issues concerning radiation protection in space are discussed. [less ▲]

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See detailImpaired Acquisition Of A Mirror-Reading Skill In Alzheimer’s Disease
Merbah, Sarah ULg; Salmon, Eric ULg; Meulemans, Thierry ULg

in Cortex : A Journal Devoted to the Study of the Nervous System & Behavior (2011), 47

Several studies using the mirror-reading paradigm have shown that procedural learning and repetition priming may be preserved in the early stages of Alzheimer's disease (AD) (e.g., Deweer et al., 1994 ... [more ▼]

Several studies using the mirror-reading paradigm have shown that procedural learning and repetition priming may be preserved in the early stages of Alzheimer's disease (AD) (e.g., Deweer et al., 1994). According to the classical interpretation, improved reading time for repeated words is sustained by a repetition priming effect, while procedural learning is demonstrated when this improvement is also observed for new words. Following Masson (1986), the hypothesis tested in the present study was that improved reading of new words could also be due to a repetition priming effect rather than to the acquisition of a mirror-reading skill. Indeed, because the same letters are presented throughout the task, a repetition priming effect for the letters could suffice to explain the improvement in performance. To test this hypothesis, we administered to 30 healthy young and elderly subjects and to 30 AD patients a new mirror-reading task in two phases: an acquisition phase comprising pseudo-words constructed with one part of the alphabet, and a test phase in which both pseudo-words constructed with the same part of the alphabet and pseudo-words constructed with another part of the alphabet were presented. If the new pseudo-words composed with repeated letters were read faster, it would reflect a repetition priming effect; if pseudo-words composed of ‘new’ letters were read faster, it would reflect a procedural learning effect. The results show comparable repetition priming effects in AD patients and in healthy elderly subjects, whereas only healthy subjects showed a procedural learning effect. These results suggest, contrary to previous studies, that the learning of a new perceptual skill may not always be preserved in AD. [less ▲]

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See detailFinal results of NKTR-102, a topoisomerase I inhibitor-polymer conjugate, in patients (Pts) with pretreated metastatic breast cancer (MBC) demonstrating significant antitumor activity
Garcia, A; Awada, A; Chan, S et al

in Journal of Clinical Oncology (2011), 29(supplement 27),

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See detailDe invloed van een muzikale opleiding op de perceptie van de prosodie van een vreemde taal: een verkennend onderzoek
Degrave, Pauline; Rasier, Laurent ULg; Hiligsmann, Philippe

in Rasier, Laurent; Van Heuven, Vincent; Defrancq, Bart (Eds.) et al Nederlands in het perspectief van uitspraakverwerving en contrastieve taalkunde (2011)

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See detailCharacterization of a knock-down mutant deficient for isocitrate lyase in Chlamydomonas reinhardtii
Remacle, Claire ULg

in Microorganisms for bio-fuel production from sunlight, ESF conference (2011)

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See detailHet geïntegreerde contrastieve onderzoeksdesign onder de loep
Hiligsmann, Philippe; Rasier, Laurent ULg

in Rasier, Laurent; Van Heuven, Vincent; Defrancq, Bart (Eds.) et al Nederlands in het perspectief van uitspraakverwerving en contrastieve taalkunde (2011)

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See detailConvergence of Logic of Cellular Regulation in Different Premalignant Cells by an Information Theoretic Approach
Kravchenko-Balasha, N.; Remacle, Françoise ULg; Gross, A. et al

in BMC Systems Biology (2011), 5

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See detailConstraining statistical-model parameters using fusion and spallation reactions
Mancusi, D.; Charity, R. J.; Cugnon, Joseph ULg

in European Physics Journal: Web of conferences (2011)

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See detailSubtrochanteric fractures after long-term treatment with bisphosphonates: a European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis, and International Osteoporosis Foundation Working Group Report.
Rizzoli, R.; Akesson, K.; Bouxsein, M. et al

in Osteoporosis International (2011), 22

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this ... [more ▼]

This paper reviews the evidence for an association between atypical subtrochanteric fractures and long-term bisphosphonate use. Clinical case reports/reviews and case-control studies report this association, but retrospective phase III trial analyses show no increased risk. Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is yet unproven. INTRODUCTION: A Working Group of the European Society on Clinical and Economic Aspects of Osteoporosis and Osteoarthritis and the International Osteoporosis Foundation has reviewed the evidence for a causal association between subtrochanteric fractures and long-term treatment with bisphosphonates, with the aim of identifying areas for further research and providing recommendations for physicians. METHODS: A PubMed search of literature from 1994 to May 2010 was performed using key search terms, and articles pertinent to subtrochanteric fractures following bisphosphonate use were analysed. RESULTS: Several clinical case reports and case reviews report a possible association between atypical fractures at the subtrochanteric region of the femur in bisphosphonate-treated patients. Common features of these 'atypical' fractures include prodromal pain, occurrence with minimal/no trauma, a thickened diaphyseal cortex and transverse fracture pattern. Some small case-control studies report the same association, but a large register-based study and retrospective analyses of phase III trials of bisphosphonates do not show an increased risk of subtrochanteric fractures with bisphosphonate use. The number of atypical subtrochanteric fractures in association with bisphosphonates is an estimated one per 1,000 per year. It is recommended that physicians remain vigilant in assessing their patients treated with bisphosphonates for the treatment or prevention of osteoporosis and advise patients of the potential risks. CONCLUSIONS: Bisphosphonate use may be associated with atypical subtrochanteric fractures, but the case is unproven and requires further research. Were the case to be proven, the risk-benefit ratio still remains favourable for use of bisphosphonates to prevent fractures. [less ▲]

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See detailInfluence of veneer thickness on residual stress profile in veneering ceramic: Measurement by hole-drilling.
MAINJOT, Amélie ULg; Schajer, G. S.; Vanheusden, Alain ULg et al

in Dental Materials (2011)

OBJECTIVES: The veneering process of frameworks induces residual stresses and can initiate cracks when combined with functional stresses. The stress distribution within the veneering ceramic as a function ... [more ▼]

OBJECTIVES: The veneering process of frameworks induces residual stresses and can initiate cracks when combined with functional stresses. The stress distribution within the veneering ceramic as a function of depth is a key factor influencing failure by chipping. This is a well-known problem with Yttria-tetragonal-zirconia-polycrystal based fixed partial dentures. The objective of this study is to investigate the influence of veneer thickness on the stress profile in zirconia- and metal-based structures. METHODS: The hole-drilling method, often used for engineering measurements, was adapted for use with veneering ceramic. The stress profile was measured in bilayered disc samples of 20mm diameter, with a 1mm thick zirconia or metal framework. Different veneering ceramic thicknesses were performed: 1mm, 1.5mm, 2mm, 2.5mm and 3mm. RESULTS: All samples exhibited the same type of stress vs. depth profile, starting with compressive at the ceramic surface, decreasing with depth up to 0.5-1.0mm from the surface, and then becoming compressive again near the framework, except for the 1.5mm-veneered zirconia samples which exhibited interior tensile stresses. Stresses in the surface of metal samples were not influenced by veneer thickness. Variation of interior stresses at 1.2mm from the surface in function of veneer thickness was inverted for metal and zirconia samples. SIGNIFICANCE: Veneer thickness influences in an opposite way the residual stress profile in metal- and in zirconia-based structures. A three-step approach and the hypothesis of the crystalline transformation are discussed to explain the less favorable residual stress development in zirconia samples. [less ▲]

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