References of "2011"
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See detailSexual arousal, is it for mammals only?
Ball, Gregory F; Balthazart, Jacques ULiege

in Hormones and Behavior (2011), 59(5), 645-55

Sexual arousal has many dimensions and has consequently been defined in various ways. In humans, sexual arousal can be assessed based in part on verbal communication. In male non-human mammalian species ... [more ▼]

Sexual arousal has many dimensions and has consequently been defined in various ways. In humans, sexual arousal can be assessed based in part on verbal communication. In male non-human mammalian species, it has been argued that arousal can only be definitively inferred if the subject exhibits a penile erection in a sexual context. In non-mammalian species that lack an intromittent organ, as is the case for most avian species, the question of how to assess sexual arousal has not been thoroughly addressed. Based on studies performed in male Japanese quail, we argue that several behavioral or physiological characteristics provide suitable measures of sexual arousal in birds and probably also in other tetrapods. These indices include, the performance of appetitive sexual behavior in anticipation of copulation (although anticipation and arousal are not synonymous), the activation of specific brain area as identified by the detection of the expression of immediate early genes (fos, egr-1) or by 2-deoxygucose quantitative autoradiography, and above all, by the release of dopamine in the medial preoptic area as measured by in vivo dialysis. Based on these criteria, it is possible to assess in birds sexual arousal in its broadest sense but meeting the more restrictive definition of arousal proposed for male mammals (erection in an explicit sexual context) is and will probably remain impossible in birds until refinement of in vivo imaging techniques such fMRI allow us to match in different species, with and without an intromittent organ, the brain areas that are activated in the presence of specific stimuli. [less ▲]

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See detailLe dosage de l'inuline: mise au point
DELANAYE, Pierre ULiege; Souvignet, Marie; Dubourg, Laurence et al

in Annales de Biologie Clinique (2011), 69(3), 273-84

L’inuline, polymère de fructose, reste le marqueur de référence du débit de filtration glomérulaire (DFG). Popularisé par les études de Smith et Shannon, son dosage n’en demeure pas moins complexe et ... [more ▼]

L’inuline, polymère de fructose, reste le marqueur de référence du débit de filtration glomérulaire (DFG). Popularisé par les études de Smith et Shannon, son dosage n’en demeure pas moins complexe et sujet à des interférences dont celle du glucose est la plus importante. Il existe deux grands types de dosages de l’inuline : les méthodes de dosage « acide » et enzymatiques. Le dosage « acide » consiste en un dosage colorimétrique du fructose obtenu après hydrolyse de l’inuline en milieu très acide. Le dosage du fructose englobe différentes méthodes de dosage dont la plus utilisée est la réaction à l’anthrone. Toutes ces méthodes présentent des interférences au glucose. Différentes méthodes « enzymatiques » ont été décrites au cours du temps. Celles-ci apparaissent plus précises et sans doute moins sujettes aux interférences même si peu d’études comparatives sont disponibles. Plusieurs auteurs ont également développé des dosages de type CLHP. Cette méthode spécifique et précise demeure cependant moins adaptée à la routine. Ainsi, si l’utilisation de l’inuline comme marqueur de référence n’est pas remise en cause, son dosage reste délicat, sujet aux interférences et à une certaine interprétation. Des études supplémentaires restent nécessaires pour valider analytiquement et comparativement les techniques de dosage de l’inuline. [less ▲]

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See detailH1N1 vaccines in a large observational cohort of patients with inflammatory bowel disease treated with immunomodulators and biological therapy.
Rahier, Jean-Francois; Papay, Pavol; Salleron, Julia et al

in Gut (2011), 60(4), 456-62

BACKGROUND: Safety data are lacking on influenza vaccination in general and on A (H1N1)v vaccination in particular in patients with inflammatory bowel disease (IBD) receiving immmunomodulators and/or ... [more ▼]

BACKGROUND: Safety data are lacking on influenza vaccination in general and on A (H1N1)v vaccination in particular in patients with inflammatory bowel disease (IBD) receiving immmunomodulators and/or biological therapy. AIMS AND METHODS: The authors conducted a multicentre observational cohort study to evaluate symptoms associated with influenza H1N1 adjuvanted (Pandemrix, Focetria, FluvalP) and non-adjuvanted (Celvapan) vaccines and to assess the risk of flare of IBD after vaccination. Patients with stable IBD treated with immunomodulators and/or biological therapy were recruited from November 2009 until March 2010 in 12 European countries. Harvey-Bradshaw Index and Partial Mayo Score were used to assess disease activity before and 4 weeks after vaccination in Crohn's disease (CD) and ulcerative colitis (UC). Vaccination-related events up to 7 days after vaccination were recorded. RESULTS: Of 575 patients enrolled (407 CD, 159 UC and nine indeterminate colitis; 53.9% female; mean age 40.3 years, SD 13.9), local and systemic symptoms were reported by 34.6% and 15.5% of patients, respectively. The most common local and systemic reactions were pain in 32.8% and fatigue in 6.1% of subjects. Local symptoms were more common with adjuvanted (39.3%) than non-adjuvanted (3.9%) vaccines (p < 0.0001), whereas rates of systemic symptoms were similar with both types (15.0% vs 18.4%, p = 0.44). Among the adjuvanted group, Pandemrix more often induced local reactions than FluvalP and Focetria (51.2% vs 27.6% and 15.4%, p < 0.0001). Solicited adverse events were not associated with any patient characteristics, specific immunomodulatory treatment, or biological therapy. Four weeks after vaccination, absence of flare was observed in 377 patients with CD (96.7%) and 151 with UC (95.6%). CONCLUSION: Influenza A (H1N1)v vaccines are well tolerated in patients with IBD. Non-adjuvanted vaccines are associated with fewer local reactions. The risk of IBD flare is probably not increased after H1N1 vaccination. [less ▲]

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See detailLes billes alginate-chitosane : un nouveau biomatériau pour la réparation des lésions du cartilage
Oprenyeszk, Frédéric ULiege; Sanchez, Christelle ULiege; Dubuc, Jean-Emile et al

in Revue du Rhumatisme (2011), 78(suppl 5), 129-130

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See detailPattern granulomateux dans les pathologies inflammatoires cutanées
QUATRESOOZ, Pascale ULiege

Scientific conference (2011)

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See detailSyllabus Histoire de la littérature néerlandaise I
Steyaert, Kris ULiege

Learning material (2011)

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See detailMagnetic susceptibility evolution in the Eifelian-Givetian Baileux section (Baileux section): complex origin of the magnetic susceptibility signal
Da Silva, Anne-Christine ULiege; Dekkers, Mark; Mabille, Cédric et al

in Koptikova, Leona; Hladil, Jindrich; Adamovic, Jiri (Eds.) Miroslav Krs conference: time, magnetism, records, systems and solution. The 2011 Annual IGCP-580 Meeting. Abstract volume (2011)

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See detailSafety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition – First Pilot Results
Shaw, Geoffrey M.; Le Compte, Aaron; Evans, Alicia et al

in Intensive Care Medicine (2011)

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See detailCompte rendu de D. POTTER, Renaissance France at War
Masson, Christophe ULiege

in Moyen Age (Le) (2011), CXVII

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See detailPreserved feedforward but impaired top-down processes in the vegetative state.
Boly, Mélanie ULiege; Garrido, Marta Isabel; Gosseries, Olivia ULiege et al

in Science (2011), 332(6031), 858-62

Frontoparietal cortex is involved in the explicit processing (awareness) of stimuli. Frontoparietal activation has also been found in studies of subliminal stimulus processing. We hypothesized that an ... [more ▼]

Frontoparietal cortex is involved in the explicit processing (awareness) of stimuli. Frontoparietal activation has also been found in studies of subliminal stimulus processing. We hypothesized that an impairment of top-down processes, involved in recurrent neuronal message-passing and the generation of long-latency electrophysiological responses, might provide a more reliable correlate of consciousness in severely brain-damaged patients, than frontoparietal responses. We measured effective connectivity during a mismatch negativity paradigm and found that the only significant difference between patients in a vegetative state and controls was an impairment of backward connectivity from frontal to temporal cortices. This result emphasizes the importance of top-down projections in recurrent processing that involve high-order associative cortices for conscious perception. [less ▲]

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See detailIndol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Dolusic, Eduard; Larrieu, Pierre; Blanc, Sébastien et al

in Bioorganic & Medicinal Chemistry (2011), 19(4), 1550-61

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships ... [more ▼]

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships (SAR) of a novel series of IDO inhibitors based on the indol-2-yl ethanone scaffold is described. In vitro and in vivo biological activities have been evaluated, leading to compounds with IC(50) values in the micromolar range in both tests. Introduction of small substituents in the 5- and 6-positions of the indole ring, indole N-methylation and variations of the aromatic side chain are all well tolerated. An iron coordinating group on the linker is a prerequisite for biological activity, thus corroborating the virtual screening results. [less ▲]

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See detail1997–2007 CO trend at the high Alpine site Jungfraujoch: a comparison between NDIR surface in situ and FTIR remote sensing observations
Dils, B.; Cui, J.; Henne, S. et al

in Atmospheric Chemistry and Physics (2011), 11(13), 6735--6748

Within the atmospheric research community, there is a strong interest in integrated datasets, combining data from several instrumentations. This integration is complicated by the different characteristics ... [more ▼]

Within the atmospheric research community, there is a strong interest in integrated datasets, combining data from several instrumentations. This integration is complicated by the different characteristics of the datasets, inherent to the measurement techniques. Here we have compared two carbon monoxide time series (1997 till 2007) acquired at the high-Alpine research station Jungfraujoch (3580 m above sea level), with two well-established measurement techniques, namely in situ surface concentration measurements using Non-Dispersive Infrared Absorption technology (NDIR), and ground-based remote sensing measurements using solar absorption Fourier Transform Infrared spectrometry (FTIR). The profile information available in the FTIR signal allowed us to extract an independent layer with a top height of 7.18 km above sea level, appropriate for comparison with our in situ measurements. We show that, even if both techniques are able to measure free troposphere CO concentrations, the datasets exhibit marked differences in their overall trends (−3.21 ± 0.03 ppb/year for NDIR vs. −0.8 ± 0.4 ppb/year for FTIR). Removing measurements that are polluted by uprising boundary layer air has a strong impact on the NDIR trend (now −2.62 ± 0.03 ppb/year), but its difference with FTIR remains significant. Using the LAGRANTO trajectory model, we show that both measurement techniques are influenced by different source regions and therefore are likely subject to exhibit significant differences in their overall trend behaviour. However the observation that the NDIR-FTIR trend difference is as significant before as after 2001 is at odds with available emission databases which claim a significant Asian CO increase after 2001 only. [less ▲]

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See detailExtended safety observations from denosumab administration in postmenopausal women from FREEDOM and FREEDOM extension trials
Brown, J. P.; Bone, H. G.; Chapurlat, R. et al

in Arthritis and Rheumatism (2011), 63(S10), 431-432

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See detailPhenotypic evaluation of interspecific recombinant inbred lines (RILs) of Phaseolus species for their resistance to aluminum and tolerance to aluminum-toxic acid soil under greenhouse conditions
Butare, Louis; Rao, I. M.; Lepoivre, Philippe ULiege et al

in Euphytica : International Journal of Plant Breeding (2011)

Aluminium (Al) toxicity limits common bean productivity in acid soil regions of the tropics. To improve Al resistance of common bean, Al-sensitive Phaseolus vulgaris (SER16) was crossed to Alresistant P ... [more ▼]

Aluminium (Al) toxicity limits common bean productivity in acid soil regions of the tropics. To improve Al resistance of common bean, Al-sensitive Phaseolus vulgaris (SER16) was crossed to Alresistant P. coccineus (G35346-3Q) to create 94 F5:6 recombinant inbred lines (RILs) of the pedigree SER16 9 (SER16 9 G35346-3Q). RILs were characterized for resistance to Al in a hydroponic system with 0 and 20 lM Al in solution, and for shoot and root growth response to Al-toxic infertile acid soil in 75 cm long soil cylinder system using an oxisol of low Al- (12.5%; pH 4.6; fertilized) and high Al-saturation (77%; pH 4.1; unfertilized). G35346-3Q increased its taproot elongation rate by 3.5% between 24 and 48 h under 20 lM Al in solution, while the best RIL, Andean genotype ICA Quimbaya, and sensitive genotype VAX1 expressed reductions of 2.6, 12.5, and 69.5%, respectively. In the acid soil treatment the correlation between leaf area and total root length was highly significant under high Al saturation (r = 0.70***). Genotypes that were Al resistant in the hydroponic system were not necessarily tolerant to Al-toxic acid soil conditions based on shoot and root growth responses. Phenotypic evaluation using both systems allows the identification of genotypes with Al resistance combined with acid soil adaptation. Two genotypes (ALB88 and ALB91) emerged as lines with multiple traits. Results suggest that inheritance of Al resistance and acid soil tolerance in G35346-3Q is complex. Results from this work will be useful for identification of molecular markers for Al resistance in Phaseolus species and to improve acid soil adaptation in common bean. [less ▲]

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See detailGenetic evidence for a TatC dimer at the core of the Escherichia coli twin arginine (Tat) protein translocase
Maldonado-Larrosa, Barbara Maria ULiege

in Journal of Molecular Microbiology & Biotechnology (2011)

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See detailMechanobiology and cell tensegrity: the root of ethnic hair curling?
Pierard-Franchimont, Claudine; PAQUET, Philippe ULiege; QUATRESOOZ, Pascale ULiege et al

in Journal of Cosmetic Dermatology (2011), 10(2), 163-7

BACKGROUND: The hair shape, either straight, crimp, or curly, is basically under genetic influence. It is possibly altered by some drugs such as cytostatic agents. In addition, specific innate molecular ... [more ▼]

BACKGROUND: The hair shape, either straight, crimp, or curly, is basically under genetic influence. It is possibly altered by some drugs such as cytostatic agents. In addition, specific innate molecular characteristics are modulated by some cosmetic procedures to reshape the hair shafts. AIM: To revisit the possible implication of mechanobiology and cell tensegrity in shaping ethnic hair. MATERIALS AND METHODS: Optical and scanning electron microscopy of hairs. RESULTS: It is generally held that the cross-section shape of hair is related to differences in the global aspect of the hair shaft. A possible biologic link between these features may rely on shaping cell tensegrity at any portion of the hair shaft. Cell tensegrity encompasses all intrinsic and extrinsic forces responsible for the three-dimensional arrangement of intracellular macromolecules. CONCLUSION: We offer as a hypothesis that the hair shape in part depends on the organization of the cell proliferation in the hair matrix. This review gathers observations supporting the involvement of cell tensegrity in shaping the hair shaft. [less ▲]

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See detailGlycemic Variability, Hypoglycemia and Organ Failure in the Glucontrol Study
Penning, Sophie ULiege; Le Compte, Aaron J.; PREISER, Jean-Charles ULiege et al

in 10th Belgian Day on Biomedical Engineering (2011)

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See detailDes outils pour soutenir les apprenants en bachelier - Aide à la résolution de problèmes en physique. Aide à la maîtrise de la langue française.
Jacquet, Maud; Gourdange, Brigitte; Maes, Estelle et al

Report (2011)

Le rapport rend compte des actions mises en oeuvre pour soutenir les bacheliers dans leur apprentissage de la physique (en médecine) et du français (en logopédie). Ces actions sont supportées par des ... [more ▼]

Le rapport rend compte des actions mises en oeuvre pour soutenir les bacheliers dans leur apprentissage de la physique (en médecine) et du français (en logopédie). Ces actions sont supportées par des dispositifs d'apprentissage en ligne. [less ▲]

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