References of "2011"
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See detailPattern granulomateux dans les pathologies inflammatoires cutanées
QUATRESOOZ, Pascale ULg

Scientific conference (2011)

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See detailSyllabus Histoire de la littérature néerlandaise I
Steyaert, Kris ULg

Learning material (2011)

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See detailMagnetic susceptibility evolution in the Eifelian-Givetian Baileux section (Baileux section): complex origin of the magnetic susceptibility signal
Da Silva, Anne-Christine ULg; Dekkers, Mark; Mabille, Cédric et al

in Koptikova, Leona; Hladil, Jindrich; Adamovic, Jiri (Eds.) Miroslav Krs conference: time, magnetism, records, systems and solution. The 2011 Annual IGCP-580 Meeting. Abstract volume (2011)

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See detailSafety and Performance of Stochastic Targeted (STAR) Glycemic Control of Insulin and Nutrition – First Pilot Results
Shaw, Geoffrey M.; Le Compte, Aaron; Evans, Alicia et al

in Intensive Care Medicine (2011)

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See detailCompte rendu de D. POTTER, Renaissance France at War
Masson, Christophe ULg

in Moyen Age (Le) (2011), CXVII

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See detailPreserved feedforward but impaired top-down processes in the vegetative state.
Boly, Mélanie ULg; Garrido, Marta Isabel; Gosseries, Olivia ULg et al

in Science (2011), 332(6031), 858-62

Frontoparietal cortex is involved in the explicit processing (awareness) of stimuli. Frontoparietal activation has also been found in studies of subliminal stimulus processing. We hypothesized that an ... [more ▼]

Frontoparietal cortex is involved in the explicit processing (awareness) of stimuli. Frontoparietal activation has also been found in studies of subliminal stimulus processing. We hypothesized that an impairment of top-down processes, involved in recurrent neuronal message-passing and the generation of long-latency electrophysiological responses, might provide a more reliable correlate of consciousness in severely brain-damaged patients, than frontoparietal responses. We measured effective connectivity during a mismatch negativity paradigm and found that the only significant difference between patients in a vegetative state and controls was an impairment of backward connectivity from frontal to temporal cortices. This result emphasizes the importance of top-down projections in recurrent processing that involve high-order associative cortices for conscious perception. [less ▲]

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See detailIndol-2-yl ethanones as novel indoleamine 2,3-dioxygenase (IDO) inhibitors.
Dolusic, Eduard; Larrieu, Pierre; Blanc, Sébastien et al

in Bioorganic & Medicinal Chemistry (2011), 19(4), 1550-61

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships ... [more ▼]

Indoleamine 2,3-dioxygenase (IDO) is a heme dioxygenase which has been shown to be involved in the pathological immune escape of diseases such as cancer. The synthesis and structure-activity relationships (SAR) of a novel series of IDO inhibitors based on the indol-2-yl ethanone scaffold is described. In vitro and in vivo biological activities have been evaluated, leading to compounds with IC(50) values in the micromolar range in both tests. Introduction of small substituents in the 5- and 6-positions of the indole ring, indole N-methylation and variations of the aromatic side chain are all well tolerated. An iron coordinating group on the linker is a prerequisite for biological activity, thus corroborating the virtual screening results. [less ▲]

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See detail1997–2007 CO trend at the high Alpine site Jungfraujoch: a comparison between NDIR surface in situ and FTIR remote sensing observations
Dils, B.; Cui, J.; Henne, S. et al

in Atmospheric Chemistry and Physics (2011), 11(13), 6735--6748

Within the atmospheric research community, there is a strong interest in integrated datasets, combining data from several instrumentations. This integration is complicated by the different characteristics ... [more ▼]

Within the atmospheric research community, there is a strong interest in integrated datasets, combining data from several instrumentations. This integration is complicated by the different characteristics of the datasets, inherent to the measurement techniques. Here we have compared two carbon monoxide time series (1997 till 2007) acquired at the high-Alpine research station Jungfraujoch (3580 m above sea level), with two well-established measurement techniques, namely in situ surface concentration measurements using Non-Dispersive Infrared Absorption technology (NDIR), and ground-based remote sensing measurements using solar absorption Fourier Transform Infrared spectrometry (FTIR). The profile information available in the FTIR signal allowed us to extract an independent layer with a top height of 7.18 km above sea level, appropriate for comparison with our in situ measurements. We show that, even if both techniques are able to measure free troposphere CO concentrations, the datasets exhibit marked differences in their overall trends (−3.21 ± 0.03 ppb/year for NDIR vs. −0.8 ± 0.4 ppb/year for FTIR). Removing measurements that are polluted by uprising boundary layer air has a strong impact on the NDIR trend (now −2.62 ± 0.03 ppb/year), but its difference with FTIR remains significant. Using the LAGRANTO trajectory model, we show that both measurement techniques are influenced by different source regions and therefore are likely subject to exhibit significant differences in their overall trend behaviour. However the observation that the NDIR-FTIR trend difference is as significant before as after 2001 is at odds with available emission databases which claim a significant Asian CO increase after 2001 only. [less ▲]

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See detailExtended safety observations from denosumab administration in postmenopausal women from FREEDOM and FREEDOM extension trials
Brown, J. P.; Bone, H. G.; Chapurlat, R. et al

in Arthritis and Rheumatism (2011), 63(S10), 431-432

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See detailPhenotypic evaluation of interspecific recombinant inbred lines (RILs) of Phaseolus species for their resistance to aluminum and tolerance to aluminum-toxic acid soil under greenhouse conditions
Butare, Louis; Rao, I. M.; Lepoivre, Philippe ULg et al

in Euphytica : International Journal of Plant Breeding (2011)

Aluminium (Al) toxicity limits common bean productivity in acid soil regions of the tropics. To improve Al resistance of common bean, Al-sensitive Phaseolus vulgaris (SER16) was crossed to Alresistant P ... [more ▼]

Aluminium (Al) toxicity limits common bean productivity in acid soil regions of the tropics. To improve Al resistance of common bean, Al-sensitive Phaseolus vulgaris (SER16) was crossed to Alresistant P. coccineus (G35346-3Q) to create 94 F5:6 recombinant inbred lines (RILs) of the pedigree SER16 9 (SER16 9 G35346-3Q). RILs were characterized for resistance to Al in a hydroponic system with 0 and 20 lM Al in solution, and for shoot and root growth response to Al-toxic infertile acid soil in 75 cm long soil cylinder system using an oxisol of low Al- (12.5%; pH 4.6; fertilized) and high Al-saturation (77%; pH 4.1; unfertilized). G35346-3Q increased its taproot elongation rate by 3.5% between 24 and 48 h under 20 lM Al in solution, while the best RIL, Andean genotype ICA Quimbaya, and sensitive genotype VAX1 expressed reductions of 2.6, 12.5, and 69.5%, respectively. In the acid soil treatment the correlation between leaf area and total root length was highly significant under high Al saturation (r = 0.70***). Genotypes that were Al resistant in the hydroponic system were not necessarily tolerant to Al-toxic acid soil conditions based on shoot and root growth responses. Phenotypic evaluation using both systems allows the identification of genotypes with Al resistance combined with acid soil adaptation. Two genotypes (ALB88 and ALB91) emerged as lines with multiple traits. Results suggest that inheritance of Al resistance and acid soil tolerance in G35346-3Q is complex. Results from this work will be useful for identification of molecular markers for Al resistance in Phaseolus species and to improve acid soil adaptation in common bean. [less ▲]

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See detailGenetic evidence for a TatC dimer at the core of the Escherichia coli twin arginine (Tat) protein translocase
Maldonado-Larrosa, Barbara Maria ULg

in Journal of Molecular Microbiology & Biotechnology (2011)

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See detailMechanobiology and cell tensegrity: the root of ethnic hair curling?
Pierard-Franchimont, Claudine; PAQUET, Philippe ULg; QUATRESOOZ, Pascale ULg et al

in Journal of Cosmetic Dermatology (2011), 10(2), 163-7

BACKGROUND: The hair shape, either straight, crimp, or curly, is basically under genetic influence. It is possibly altered by some drugs such as cytostatic agents. In addition, specific innate molecular ... [more ▼]

BACKGROUND: The hair shape, either straight, crimp, or curly, is basically under genetic influence. It is possibly altered by some drugs such as cytostatic agents. In addition, specific innate molecular characteristics are modulated by some cosmetic procedures to reshape the hair shafts. AIM: To revisit the possible implication of mechanobiology and cell tensegrity in shaping ethnic hair. MATERIALS AND METHODS: Optical and scanning electron microscopy of hairs. RESULTS: It is generally held that the cross-section shape of hair is related to differences in the global aspect of the hair shaft. A possible biologic link between these features may rely on shaping cell tensegrity at any portion of the hair shaft. Cell tensegrity encompasses all intrinsic and extrinsic forces responsible for the three-dimensional arrangement of intracellular macromolecules. CONCLUSION: We offer as a hypothesis that the hair shape in part depends on the organization of the cell proliferation in the hair matrix. This review gathers observations supporting the involvement of cell tensegrity in shaping the hair shaft. [less ▲]

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See detailGlycemic Variability, Hypoglycemia and Organ Failure in the Glucontrol Study
Penning, Sophie ULg; Le Compte, Aaron J.; PREISER, Jean-Charles ULg et al

in 10th Belgian Day on Biomedical Engineering (2011)

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See detailDes outils pour soutenir les apprenants en bachelier - Aide à la résolution de problèmes en physique. Aide à la maîtrise de la langue française.
Jacquet, Maud; Gourdange, Brigitte; Maes, Estelle et al

Report (2011)

Le rapport rend compte des actions mises en oeuvre pour soutenir les bacheliers dans leur apprentissage de la physique (en médecine) et du français (en logopédie). Ces actions sont supportées par des ... [more ▼]

Le rapport rend compte des actions mises en oeuvre pour soutenir les bacheliers dans leur apprentissage de la physique (en médecine) et du français (en logopédie). Ces actions sont supportées par des dispositifs d'apprentissage en ligne. [less ▲]

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See detailEffect of imputing markers from a low-density chip on the reliability of genomic breeding values in Holstein populations.
Dassonneville, Romain; Brondum, R. F.; Druet, Tom ULg et al

in Journal of Dairy Science (2011), 94(7), 3679-86

The purpose of this study was to investigate the imputation error and loss of reliability of direct genomic values (DGV) or genomically enhanced breeding values (GEBV) when using genotypes imputed from a ... [more ▼]

The purpose of this study was to investigate the imputation error and loss of reliability of direct genomic values (DGV) or genomically enhanced breeding values (GEBV) when using genotypes imputed from a 3,000-marker single nucleotide polymorphism (SNP) panel to a 50,000-marker SNP panel. Data consisted of genotypes of 15,966 European Holstein bulls from the combined EuroGenomics reference population. Genotypes with the low-density chip were created by erasing markers from 50,000-marker data. The studies were performed in the Nordic countries (Denmark, Finland, and Sweden) using a BLUP model for prediction of DGV and in France using a genomic marker-assisted selection approach for prediction of GEBV. Imputation in both studies was done using a combination of the DAGPHASE 1.1 and Beagle 2.1.3 software. Traits considered were protein yield, fertility, somatic cell count, and udder depth. Imputation of missing markers and prediction of breeding values were performed using 2 different reference populations in each country: either a national reference population or a combined EuroGenomics reference population. Validation for accuracy of imputation and genomic prediction was done based on national test data. Mean imputation error rates when using national reference animals was 5.5 and 3.9% in the Nordic countries and France, respectively, whereas imputation based on the EuroGenomics reference data set gave mean error rates of 4.0 and 2.1%, respectively. Prediction of GEBV based on genotypes imputed with a national reference data set gave an absolute loss of 0.05 in mean reliability of GEBV in the French study, whereas a loss of 0.03 was obtained for reliability of DGV in the Nordic study. When genotypes were imputed using the EuroGenomics reference, a loss of 0.02 in mean reliability of GEBV was detected in the French study, and a loss of 0.06 was observed for the mean reliability of DGV in the Nordic study. Consequently, the reliability of DGV using the imputed SNP data was 0.38 based on national reference data, and 0.48 based on EuroGenomics reference data in the Nordic validation, and the reliability of GEBV using the imputed SNP data was 0.41 based on national reference data, and 0.44 based on EuroGenomics reference data in the French validation. [less ▲]

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See detailOn Reflections and Reflexivity: Unpacking Research Dispositifs
Thoreau, François ULg

in Zülsdorf, Torben; Coenen, Christopher; Ferrari, Arianna (Eds.) et al Quantum Engagements: Social Reflections of Nanoscience and Emerging Technologies (2011)

Abstract. Science and Technology Studies (STS) scholars increasingly engage with science and technology (S&T) practitioners, scientists, engineers, and the like. The actual dynamics of these engagements ... [more ▼]

Abstract. Science and Technology Studies (STS) scholars increasingly engage with science and technology (S&T) practitioners, scientists, engineers, and the like. The actual dynamics of these engagements differ from one project, framework or school to the next. However, to be reflexive, such engagements need at some point to deal with the ambiguous relationship between ‘engager’ and ‘engaged’. In an attempt to disambiguate these interactive ties, this chapter takes inspiration from Vinciane Despret, a philosopher of science who has provided ethnographic studies of ethologists. It specifically draws on two of Despret’s arguments about experiments on animals, more precisely rats, and the paradoxical relationships to which they give rise. By means of analogy, it then illustrates the similar ways in which we, as STS scholars, might happen to frame our interactions with S&T practitioners. It argues that any experimental research dispositif necessarily implies a specific relationship dynamic with whoever is engaged. This should not be considered as an obstacle, but instead an opportunity for learning—yet only if the dispositif is open to protest. The analysis here took shape during an engagement study conducted at a large-scale R&D center in Flanders, Belgium. It is informed by ongoing involvement in a broader research project (STIR) that aims at fostering reflexivity among S&T practitioners. [less ▲]

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See detailResearch of Structural Health Monitoring Based on Mode Analysis for UAV Wings
Guo, Yingnan; Wan, Fangyi; Wu, Ling ULg et al

in Prognostics and System Health Management Conference (PHM-Shenzhen), 2011 IEEE Conference on (2011)

Unmanned Aerial Vehicle (UA V) structures are prone to damage during their service lives, caused by abominable environment factors. Its structural health monitoring can be effective in reducing ... [more ▼]

Unmanned Aerial Vehicle (UA V) structures are prone to damage during their service lives, caused by abominable environment factors. Its structural health monitoring can be effective in reducing maintenance costs and increasing service life to ensure safe and reliable operation. Two different damaged modal parameters based on modal analysis is discussed in this paper in order to develop an efficient damage identification technique for the UA V wing structures. Its structure modal is a natural attribute of structures, and apparently one of the most important parameters of structure dynamic characteristics. For a well designed aircraft wings structures, its modal pattern should be continuous without local mode. Therefore, based on the modal analysis utilizing numerical methods for a damaged structure, damages location and its extent can be revealed and damage level can be evaluated. All the numerical results illustrated these method are efficient and feasible for structural damage detection. And its can be utilized in structure [less ▲]

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See detailOstéroporose, le mal sournois
Reginster, Jean-Yves ULg

in Athena (2011), 276

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